Kostas Markatos

Kostas Markatos
Salamina Medical Center · Orthopaedics

B.Sc., M.Sc., M.D., Ph.D.

About

106
Publications
60,493
Reads
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462
Citations
Introduction
Kostas Markatos currently works for the National Health System of Greece. Kostas does research in Surgery, Sports Medicine and Orthopedic Surgery and history of medicine and surgery. He specializes in the history of medicine and surgery in the years of the scientific revolution. He also practices orthopaedic surgery and orthopaedic medicine.
Additional affiliations
December 2016 - September 2020
Kapandriti Medical Center
Position
  • Orthopaedic Surgeon
Description
  • non-tenured orthopaedic consultant
January 2014 - December 2016
Henry Dunant Hospital
Position
  • Consultant
Description
  • Junior Consultant
November 2008 - June 2015
National and Kapodistrian University of Athens
Position
  • Resident in Orthopaedics- PhD Student
Education
June 2012 - September 2015
National and Kapodistrian University of Athens
Field of study
  • Orthopaedics- Neurosurgery- Spine Surgery
November 2008 - April 2013
October 2008 - May 2011
National Technical University of Athens
Field of study
  • Theory and Methodology of Science

Publications

Publications (106)
Article
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mHealth (mobile health) refers to mobile technologies that aid medical and public health practices. As of February 2019, 81% of Americans own a smartphone, and mHealth applications (apps) have become increasingly common with more than 400,000 mHealth applications currently available. Advancements in mobile technology now allow us to provide persona...
Article
Total hip replacement remains one of the most successful and popular operative techniques in orthopedic surgery. Over several decades, several patients have been benefited by this mechanical and surgical achievement. It is an innovation that stands among the most significant surgical and technological achievements of the 20th century. The purpose o...
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PurposeThe critical literature review investigates the extent to which the current evidence supports that three-dimensional printing (3DP) could play an important role in human anatomy education.Methods PubMed, ERIC, and Cochrane databases were searched for papers dealing with the outcomes of 3DP implementation in human undergraduate anatomy educat...
Article
PurposeTo summarize the available information from mythology, archeology, and classical literature aiming to compose the image of Asclepieia, Asclepius, and the Asclepiads, and to depict the atmosphere of medicine in its infancy.MethodA thorough literature search was undertaken in PubMed and Google Scholar as well as in physical books in libraries...
Article
Until the fifteenth century, the knowledge about anatomy and function of the nervous system had been significantly influenced by theological notions. Andreas Vesalius of Brussels (1514–1564), based on human cadavers’ dissections, criticized his predecessors and contributed to the construction of the current knowledge about functional neuroanatomy....
Book
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This is the 5th updated Edition of our book enlisting all literature in spine surgery by greek authors
Article
Introduction: Aim of the present study is to present an historical overview of the surgical techniques introduced for the treatment of the cancer of the optic nerve and orbit. Methods: From the late 19th and early 20th century there were introduced many novel surgical techniques for the treatment of the cancer of the optic nerve and orbit. The majo...
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The purpose of this study is to summarize the life and work of the French surgeon Jules Pean (1830-1898). Pean made an impact in the history of surgery through his work and especially with his innovative surgical techniques in abdominal surgery and in orthopedics as well as with the invention of numerous surgical instruments. He also made an impact...
Article
Aim of the study The purpose of this historic review is to summarize the life and work of Abulcasis (936–1013) and his contribution to surgery and orthopaedics. Method We conducted an extensive search in libraries as well as online in PubMed and Google Scholar. Results Abulcasis in his work combines the knowledge of ancient Greek and Roman physic...
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Background: There is an inadequacy of conventional means to assess the surgical outcomes of a bunion surgery. We used the Finite Element Analysis for evaluating the typical Mitchell's procedure outcomes with or without bio-absorbable pins. Methods: We developed a 3D FE model based on the CT images of a female volunteer with hallux valgus. A typi...
Article
Enhanced recovery after surgery or 'fast-track' methods are evidence-based protocols designed to standardize post-operative medical care, improve patient outcomes, promote early recovery, and reduce healthcare expenditure. Fast-track surgery is a multifunctional concept involving pre-, peri- and post-operative measures aiming to reduce the length o...
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Background Hamstring tendons are widely used in anterior cruciate ligament reconstruction. Improvements in fixation materials have increased the success of the reconstruction procedures using this type of graft. The main advantage of the hamstring tendon autograft is the lower donor site morbidity associated with its harvesting. On the other hand,...
Article
The purpose of this study is to summarize the life and work of the French anatomist and surgeon Antoine Ferrein (1693-1769). Ferrein made an impact in the history of anatomy and physiology through his work and especially with the description of phonation, renal anatomy, and liver and biliary structure. He also made an impact on ophthalmology with t...
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Microsurgery is a term used to describe the surgical techniques that require an operating microscope and the necessary specialized instrumentation, the three “Ms” of Microsurgery (microscope, microinstruments and microsutures). Over the years, the crucial factor that transformed the notion of microsurgery itself was the anastomosis of successively...
Book
Full-text available
This is the 4th updated Edition of our bookenlisting all literature in spine surgery by greek authors
Article
Full-text available
Guy de Chauliac, the most famous surgeon of the middle age, influenced the practice of surgery for centuries. His landmark work, in seven treatises, "Chirurgia Magna" was translated from Latin to French and became popular across Europe, educating hundreds of surgeons. In his book, a series of text fragments were dedicated in cancer such as breast t...
Article
Galen of Pergamum (129-216/217 AD), an important Greek physician, influenced the history of medicine for more than 1400 years. However, Andreas Vesalius (1514–1564), after performing dissections of human cadavers, remarked that Galen made several mistakes due to the fact that his dissections were on animals, particularly on apes. The current study...
Article
Aim of the study The purpose of this historic review is to summarize the life and work of Avicenna (980–1037) and his contribution to the diagnosis and treatment of spinal deformities and trauma. Method We conducted an extensive search in libraries as well as online in Pubmed and Google Scholar. Results Avicenna in his work Canon of Medicine comb...
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Pycnodysostosis or Maroteaux–Lamy syndrome is a genotypic bone disorder, with autosomal recessive inheritance, individualized by Lamy and Maroteaux in 1962. It is characterized by diffuse condensation of the skeleton with thickening of the cortex and narrowing of the medullary cavity. This condensation is reminiscent of the one observed in Albers-S...
Article
Pierre Franco (1505-1578) was a brilliant surgeon of the Renaissance, a contemporary of Ambroise Paré. He made an impact on the history of surgery with his innovative approaches in the treatment of hernia, lithotomy, and the use of the suprapubic incision. The purpose of this study is to present a detailed account of his work, innovations, and achi...
Article
Purpose To summarize pharmacies for pain and trauma in ancient Greece, to present several pharmaceutical/therapeutical methods reported in myths and ancient texts, and to theorize on the medical explanation upon which these pharmacies were used. Method A thorough literature search was undertaken in PubMed and Google Scholar as well as in physical...
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The objective of this article is to showcase the use of opium in ancient times, as well as the beliefs surrounding it, focusing on the opinion of Diagoras of Cyprus, a physician with great knowledge of pharmacology who probably practiced ophthalmology, composing a rose-based collyrium. Opium, a drug produced from poppy, used to have several uses su...
Article
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In the 19 th century medicine flourished in Paris thanks to the advent of the anatomo-clinical School which introduced new methods of clinical examination and diagnosis. Pathology , auscultation and percussion became a routine in medical practice and paved the way for the rising of specialties such as cardiology and oncology. Heart cancer cases wer...
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The concept of psychosomatic disorders, as defined by modern medicine, was difficult to be perceived by the ancient Greek physicians. Two main reasons contributed to this. One was that physicians in Greek antiquity had formed the idea that the mental illnesses that were recognized at that time, namely mania, melancholy, frenzy, caros, lethargy, apo...
Article
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Histone modification that occurs through the process of acetylation plays a key role in the epigenetic regulation of gene expression. The balance between histone deacetylases (HDACs) and histone acetyltransferases controls this process. Histone deacetylase inhibitors (HDACIs) can induce cancer cell cycle arrest, differentiation and cell death, redu...
Article
Purpose: Our intention with this article is to review current literature concerning the classification of the fractures of the odontoid process and present their treatment concerning classification with special emphasis to the Korres classification that we routinely use. In addition we intend to review and summarize the classification significance...
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This study aims to detect whether there remains valuable prognostic information in fluctuation of red cell distribution width (RDW) in hip fracture patients. Results show that this readily available parameter may provide a more effective strategy for assessment of mortality risk, therefore providing a reference for clinical planning and decision-ma...
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The purpose of this article is to summarize the work and pioneering achievements in the field of orthopedic surgery of the German orthopedic surgeon Karl Ludloff. Ludloff had an impact in the diagnostics, physical examination, orthopedic imaging, and orthopedic surgical technique of his era. He was a pioneer in the surgical treatment of dysplastic...
Article
Purpose: The purpose of this review is to summarize the life and work of Jean-Louis Petit, his inventions, his discoveries, and his impact on the evolution of surgery of his era. Method: A thorough search of the literature was undertaken in PubMed and Google Scholar as well as in physical books in libraries to summarize current and classic liter...
Article
Spleen in antiquity was considered by the Hippocratic medicine as a viscerous organ of spongy character, which could clear human body of the black bile. According to the Hippocratic doctrine of the 4 humors, black bile could cause a series of diseases. Both the anatomical position and shape of the spleen were also recognized. In the case of a splen...
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Purpose: The thorough knowledge of C2 lamina anatomy is essential for the avoidance of complications during screw fixation. We performed a review of the literature, aiming to detect what was found about anatomical feasibility of C2 translaminar fixation in different populations, along with possible recommendations for the avoidance of complication...
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Objective: Endometrial cancer is increasingly prevalent in western societies and affects mainly postmenopausal women; notably incidence rates have been rising by 1.9% per year on average since 2005. Although the early-stage endometrial cancer can be effectively managed with surgery, more advanced stages of the disease require multimodality treatme...
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In our article we present the anatomical work of the distinguished Renaissance anatomist Realdo Colombo, as well as, his contribution to the discovery of pulmonary circulation. Colombo was not the first to describe the pulmonary circulation, but he backed up this hypothesis with evidence after extensive dissection and vivisection. He paved the way...
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At the beginning of the 20th century, the relation of carcinoma in situ of the cervix to the invasive cancer was poorly understood, resulting in misdiagnosis of the disease and inappropriate treatment. The work of Richard Wesley TeLinde, chairman of Gynaecology at Johns Hopkins University for almost 21 years, contributed to delineate the diagnosis...
Article
Full-text available
Histone modification that occurs through the process of acetylation plays a key role in the epigenetic regulation of gene expression. The balance between histone deacetylases (HDACs) and histone acetyltransferases controls this process. Histone deacetylase inhibitors (HDACIs) can induce cancer cell cycle arrest, differentiation and cell death, redu...
Article
Introduction: The purpose of this study is to give a brief account of the life of John II Komnenos, his reign and to clarify the events and causes surrounding his death. Methods: A thorough search of the literature was undertaken in PubMed and Google Scholar as well as in history books through the internet and in History and Medical University libr...
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Advocate of Lister's antiseptic techniques, promoter of anesthesia , professor of the first chair of gynaecology in Medical School of Paris, academician, successful politician, art collector , friend and lover of the famous, Samuel Pozzi lived a fascinating life. His book "Treatise of clinical and surgical gynaecology" published in 1890 became the...
Article
Congenital anomalies of the limbs have been observed since ancient human civilizations, capturing the imagination of ancient physicians and people. The knowledge of the era could not possibly theorize on the biologic aspects of these anomalies; however, from the very beginning of civilization the spiritual status of people attempted to find a logic...
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The purpose of this study was to summarise the life and work of the Cypriot physician Apollonius of Citium (first century BC). His overall work on medicine is presented, and special emphasis is given to his work on the treatment of joint dislocations. The most famous work of Apollonius is Treatise On Joints, which was preserved on the whole in a ma...
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Non-small cell lung cancer constitutes the most common type of lung cancer, accounting for 85-90% of lung cancer, and is a leading cause of cancer-related death. Despite the progress during the past years, poor prognosis remains a challenge and requires further research and development of novel antitumor treatment. Recently, the role of histone dea...
Article
The original version of this article was revised: The published online version contain mistake in author list. The corrected name is shown above.
Article
The purpose of this study is to summarize the innovations of Ambroise Paré (1510-1590) on the treatment of war wounds and improving amputation technique through ligature in arteries and veins. Ambroise Paré debunked the widely accepted idea that gun powder was poisonous for wounds. He also minimized the use of cautery of wounds by his dressing meth...
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OBJECTIVE: Malformations of the lymphatic system are recognized as benign congenital tumors that affect infant and children in the perinatal era. In children, these abnormalities usually found in the neck and the axillary region, but they can present in other parts of the body such as mediastinum, pelvis, retroperitoneum as well as in solid organs...
Article
The purpose of this historical review is to summarize the work of Paul of Aegina and especially his contribution to the treatment of neurosurgical disorders and trauma. Paul performed trephinations for head injuries in the tradition of the Egyptian and the Greek schools of medicine. However he was an innovator in the treatment of several spine inju...
Article
Introduction: The purpose of this study is to review and summarize the life and work of Juan Valverde de Amusco (1525–1588), his impact on the anatomy of the sixteenth century and focus on his controversy with Andreas Vesalius. Methods: A thorough search of the literature was undertaken in PubMed and Google Scholar as well as in history books throu...
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For centuries several hypotheses were formulated on can-cer's pathogenesis such as contagiousness, melancholy, heredity and sexuality. In the 18 th and 19 th century, despite the advent of medical thought and practice, cancer was considered an incurable and contagious disease. Hospitals were refusing to treat cancer patients while the social stigma...
Article
Aim of study: This article aims to summarize the treatment methods for shoulder dislocations supported by Ambroise Paré, and his clinical and academic contribution to this subject. Introduction: Ambroise Paré (1510-1590) was one of the most prominent surgeons of his time, and one of the most significant innovators of the Renaissance in the field...
Article
The purpose of this historical review is to summarize the most significant theories on the cause of death of King Henry II of France (1519-1559) and the circumstances under which it occurred. Although the testimonies are inconclusive and vague, post mortem analysis showed that the cause of death of the King was meningoencephalitis, caused by haemat...
Article
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Esophageal cancer is one of the deadliest cancers due to its aggressive behavior and poor survival. It was mentioned in the works of ancient Chinese and Arabo-islamic physicians , centuries before the recognition of high incidence in the Asian esophageal cancer belt. Till the 19 th century the disease was considered incurable and the main goal of t...
Article
The purpose of this review article is to summarize the views presented in the Hippocratic Corpus of Medicine regarding injuries of the spine, their effect on the spinal cord and the optimal treatment modulus. It is shown that the treatment dilemmas of ancient times in these injuries remain modern since Hippocrates suggested that conservative treatm...
Article
The purpose of this manuscript is to summarize the reign, life and death of Charles VIII of France. Also the authors intend to investigate current views on his cause of death, contradictions and opinions of his biographers. Poisoning, disease and injury are the possible causes of his death but, according to the literature, cranial trauma was the mo...
Article
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Fractures of the odontoid process seem to have an unclear and not well-understood behavior. This is well demonstrated in the literature as there is a disagreement in many fields, including the patterns of fractures, the percentage of pseudarthrosis or the appropriate treatment that is required. This situation makes the fracture itself a “challengin...
Article
Full-text available
Laryngeal cancer was a well known entity since antiquity and its treatment evolved through several phases. The lack of knowledge in anatomy and pathology as well as the absence of anesthesia and proper instrumentation made the treatment almost impossible. Ancient physicians were performing laryngotomy or tracheotomy in an attempt to prevent the suf...
Article
Louis-Léopold-Xavier-Édouard Ollier (1830-1900) was a pioneer in orthopedics considered as the founder of modern orthopedic surgery. He was a skillful and experimenter surgeon. He invented many new surgical techniques in orthopedic surgery and many new surgical instruments. His most known discovery is Ollier’s disease.
Article
The purpose of this historical review is to summarize the work of the Dutch physician, chemist and anatomist Gerard Blaes (Blasius). A detailed account of his life and work is presented with emphasis on his contribution to anatomy. In particular, special reference is made to his innovative description of the spinal cord and spinal nerves. The contr...
Article
Full-text available
The purpose of this historical review is to summarize the work of Paul of Aegina and especially his contribution to the treatment of Spine disorders and trauma. A major review of the literature was undertaken with emphasis on the treatise of Paul himself as well as those of later scholars and historians. Paul expanded the horizons of surgery of his...
Article
The purpose of this historic review is to summarize the life, work and contribution to anatomy of Charles Estienne (also known by the Latin name Carolus Stephanus). Charles Estienne was an early exponent of the science of anatomy in France. Although he remained under the influence of the Galenic tradition of medicine, anatomy and surgery throughout...
Article
Full-text available
OBJECTIVE: Malformations of the lymphatic system are recognized as benign congenital tumors that affect infant and children in the perinatal era. In children, these abnormalities usually found in the neck and the axillary region , but they can present in other parts of the body such as mediastinum, pelvis, retroperito-neum as well as in solid organ...