Koffi Camille

• PhD, Pharmacology
• Laboratory Assistant at Université Félix Houphouët-Boigny

Local food products are used in poultry feed in Côte d'Ivoire. The aim of the study was to assess the impact of cashew oilcake on haematological parameters in broilers. Using standard broiler feeds, experimental start-up, growth and finishing rations were formulated by substituting soybean meal for cashew meal at 0%, 25%, 50%, 75% and 100%. For 6 w...

Introduction: Kabran01, a traditional medicinal recipe is proposed by the traditional healers for treatment of diabetes in Côte d’Ivoire without scientific proof of its tolerance in humans. The aim of our work was to carry out acute toxicity tests at 2000 and 5000 mg/kg of Kabran01. Material and methods: Kabran01’s recipe includes the fresh leaves...

Objective was to compare the quality of life of herbal medicine users with those of anti-diabetic treatments in real life in type II of diabetes. Methods: This retrospective parallel group study, focused on the follow-up datas from medical record of the nine months preceding the survey-day of consenting diabetic type 2 patients included. The SF-36...

Previous studies showed that methanol extracts of Cassia siamea leaves (MLCS) reduced hyperglycemia in animal diabetic models. This study was to investigate the effect of MLCS on intestinal glucose absorption. Acute toxicity of methanol extracts of C. siamea leaves was evaluated according to OCDE 423 method in Wistar rat. Anti-hyperglycemia effect...

Native to Mexico, Persea americana Mill. (avocado) is a fruit tree whose different parts (leaf, bark, roots, and stone) are used in traditional medicine especially against diabetes mellitus. The aim of this study was to investigate the beneficial effects of 28-day treatment with aqueous, ethanolic, and methanolic leaf extracts on glucose homeostasi...

Despite long traditional utilization and some reports on the antihyperglycemic and antihyperlipidemic action of Cassia siamea, the mechanisms involved have not been investigated yet. Thus, the objective of the present study was to investigate whether and how oral administration of the ethanolic extract of Cassia siamea Lam leaves (LECS) improves gl...

Traditional remedies prepared from Lannea microcarpa leaves, barks, roots, and fruits are used to treat many diseases including hypertension. This study investigated whether oral administration of the ethyl acetate fraction of Lannea microcarpa trunk barks (LMAE) corrects angiotensin (Ang) II-induced hypertension in mice. Its effects on vascular fu...

Background: Phyllanthus amarus (Schum & Thonn), a plant belonging to the family of Euphorbiaceae is used in Ivorian traditional medicine to treat cardiovascular disorders such as hypertension. However, although this plant has been described as a diuretic agent, the underlying mechanism remains unclear. Therefore, the aim of the present study was to...

Background: Phyllanthus amarus (Schum & Thonn), a plant belonging to the family of Euphorbiaceae is used in Ivorian traditional medicine to treat cardiovascular disorders such as hypertension. However, although this plant has been described as a diuretic agent, the underlying mechanism remains unclear. Therefore, the aim of the present study was t...

Obstructive sleep apnea is characterized by intermittent hypoxia (IH) which alters endothelial function, induces inflammation and accelerates atherosclerosis-induced cardiovascular diseases. The non-muscular myosin light chain kinase (nmMLCK) isoform contributes to endothelial cell-cell junction opening. Deletion of nmMLCK protects mice from death...

Background and Objective: The leaves of Cassia siamea Lam. (Fabaceae) have been widely used in folklore medicine for the treatment of diabetes and hypertension. This study aimed to investigate if aqueous extract of C. siamea leaves can protect against hyperglycemia in experimental diabetes. Materials and methods: Preliminary, acute toxicity of a...

The aim of the present study was to compare the effect of Phyllanthus amarus extracts and its fractions on urinary excretion. Aqueous extract of Phyllanthus amarus was prepared by decoction of the whole plant and lyophilized. Ethanolic fraction and chloroformic fraction of Phyllanthus amarus were obtained from aqueous extract. Animal were divided i...

Persea americana Mill. or avocado plant tree is well-known to people from the sub-Saharan part of Africa. Studies carried out earlier reported on the use of leaf extracts of the named plant to cure diabetes and other diseases in the south of Côte d'Ivoire. This study aimed to assess both acute toxicity and hypoglyceamic activity together with perfo...

Cymbopogon citratus (DC.) Stapf is a perennial aromatic herb belonging to Poaceae (Gramineae) traditionally used to treat various diseases. Many studies have shown that this plant has an antimicrobial, antifungal, anti-inflammatory, antineoplastic, antidiabetic, antioxidant, cardiovascular, insecticide and pesticide properties. The most important m...

Cassia siamea is a shrub belonging to the Fabaceae family, native of Southeast Asia and better known in folklore medicine, feeding, agriculture and manifacture all over the world including Côte d’Ivoire. C. siamea has recently been shown to have antimicrobial, antimalarial, antidiabetic, anticancer, hypotensive, diuretic, antioxidant, laxative, ant...

Cassia siamea is a shrub belonging to the Fabaceae family, native of Southeast Asia and better known in folklore medicine, feeding, agriculture and manifacture all over the world including Côte d’Ivoire. C. siamea has recently been shown to have antimicrobial, antimalarial, antidiabetic, anticancer, hypotensive, diuretic, antioxidant, laxative, ant...

Phyllanthus amarus is a species used to treat many ailments. The hypotensive effect reported by the pharmacopoeia has been demonstrated for the aqueous extract. This effect is reduced in the presence of atropine. The aim of this work is to evaluate two fractions of P. amarus aqueous extract (EAPA), the aqueous fraction (FAPA) and ethanolic fraction...