Klaus Gramann

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Verified

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• Prof. Dr.
• Chair at Technische Universität Berlin

Recent developments in EEG hardware and analyses approaches allow for recordings in both stationary and mobile settings. Irrespective of the experimental setting, EEG recordings are contaminated with noise that has to be removed before the data can be functionally interpreted. Independent component analysis (ICA) is a commonly used tool to remove a...

Objective. Electroencephalography (EEG) studies increasingly make use of more ecologically valid experimental protocols involving mobile participants that actively engage with their environment leading to increased artifacts in the recorded data (MoBI; Gramann et al., 2011). When analyzing EEG data, especially in the mobile context, removing sample...

Magneto- and electroencephalography (M/EEG) measurements record a mix of signals from the brain, eyes, and muscles. These signals can be disentangled for artifact cleaning e.g. using spatial filtering techniques. However, correctly localizing and identifying these components relies on head models that so far only take brain sources into account. We...

Although beacon- and map-based spatial strategies are the default strategies for navigation activities, today’s navigational aids mostly follow a beacon-based design where one is provided with turn-by-turn instructions. Recent research, however, shows that our reliance on these navigational aids is causing a decline in our spatial skills. We are pr...

As we move through the world, natural and built environments implicitly guide behavior by appealing to certain sensory and motor dynamics. This process can be motivated by automatic attention to environmental features that resonate with specific sensorimotor responses. This review aims at providing a psychobiological framework describing how enviro...

Neuroadaptive haptics offers a path to more immersive extended reality (XR) experiences by dynamically tuning multisensory feedback to user preferences. We present a neuroadaptive haptics system that adapts XR feedback through reinforcement learning (RL) from explicit user ratings and brain-decoded neural signals. In a user study, participants inte...

Objects in expected locations are recognised faster and more accurately than objects in incongruent environments. This congruency effect has a neural component, with increased activity for objects in incongruent environments. Studies have increasingly shown differences between neural processes in realistic environments and tasks, and neural process...

How do humans integrate landmarks to update their spatial position during active navigation task? Using immersive virtual reality and high-density mobile EEG, we investigated the neural underpinnings of landmark-based recalibration during path integration. Our findings reveal that a briefly presented intramaze landmark effectively corrected accumul...

Assistive wearable devices can significantly enhance the quality of life for individuals with movement impairments, aid the rehabilitation process, and augment movement abilities of healthy users. However, personalizing the assistance to individual preferences and needs remains a challenge. Brain-Computer Interface (BCI) offers a promising solution...

We designed an object interception task using virtual reality and Mobile Brain/Body Imaging totest two core hypotheses of ecological psychology and radical embodied cognitive (neuro)science:the ecological resonance hypothesis and the information-based control laws hypothesis. These twohypotheses define an alternative explanatory strategy that aims...

Introduction: Parkinson's disease (PD) is characterized by enhanced beta-band activity (13–30 Hz) in the motor control regions. Simultaneously, cortico-muscular (CM) connectivity in the beta-band during iso-metric contractions tends to decline with age, in various diseases, and under dual-task conditions. Objective: This study aimed to characterize...

Everyday human cognition and behaviour evolved in dynamic and ever-changing environments, but static paradigms still dominate experimental research despite concerns about generalisability of the results. In the case of attention, traditional stationary studies show that pre-orienting attention with spatial cues leads to faster, more accurate respon...

Everyday human cognition and behaviour evolved in dynamic and ever-changing environments, but static paradigms still dominate experimental research despite concerns about generalisability of the results. In the case of attention, traditional stationary studies show that pre-orienting attention with spatial cues leads to faster, more accurate respon...

To maintain a user's sense of agency (SoA) when working with a physical motor augmentation device, the actuation must align with the user's intentions. In experiments, this is often achieved using stimulus-response paradigms where the motor augmentation can be optimally timed. However, in the everyday world users primarily act at their own volition...

Background Due to technological advancements and the development of consumer-oriented head mounted displays (HMDs), virtual reality (VR) is used in studies on balance performance and balance trainability more and more frequently. Yet, it may be assumed that balance performance is affected by the physical characteristics of the HMD (e.g., weight) as...

Affordances, the opportunities for action offered by the environment to an agent, are vital for meaningful behaviour and exist in every interaction with the environment. There is an ongoing debate in the field about whether the perception of affordances is an automated process. Some studies suggest that affordance perception is an automated process...

We present an extension to the Brain Imaging Data Structure (BIDS) for motion data. Motiondata is frequently recorded alongside human brain imaging and electrophysiological data.The goal of Motion-BIDS is to make motion data interoperable across different laboratoriesand with other data modalities in human brain and behavioral research. To this end...

Electroencephalography (EEG) studies increasingly utilize more mobile experimental protocols, leading to more and stronger artifacts in the recorded data. Independent Component Analysis (ICA) is commonly used to remove these artifacts. It is standard practice to remove artifactual samples before ICA to improve the decomposition, for example using a...

The extension to the Brain Imaging Data Structure (BIDS) for motion data (Motion-BIDS) aims to standardize the organization of motion data for reproducible research in human brain and behavioral studies. Motion data is frequently recorded alongside brain imaging and electrophysiological data, and Motion-BIDS provides a common format and metadata st...

Objects in expected locations are recognised faster and more accurately than objects in incongruent environments. This congruency effect has a neural component, with increased activity for objects in incongruent environments. Studies have increasingly shown differences between neural processes in realistic environments and tasks, and neural process...

The migration of individuals to urban centers in the last century has coincided with a rise in stress-related mental health issues among city dwellers compared to their rural counterparts. Neurourbanism, a burgeoning field, seeks to comprehend the determinants of individual well-being within the urban context. This study investigated the impact of...

Achieving temporal synchrony between sensory modalities is crucial for natural perception of object interaction in virtual reality. While subjective questionnaires are currently used to evaluate users’ VR experiences, leveraging behavior and psychophysiological responses can provide additional insights. We investigated motion and ocular behavior as...

Based on increasing incidents of mental ill-health associated with living in dense urban environments, the field of Neurourbanism developed rapidly, aiming at identifying and improving urban factors that impact the health of city dwellers. Neurourbanism and the closely related field of Neuro-Architecture have seen a surge in studies using mobile el...

Objective. Brain–computer interface (BCI) technology is poised to play a prominent role in modern work environments, especially a collaborative environment where humans and machines work in close proximity, often with physical contact. In a physical human robot collaboration (pHRC), the robot performs complex motion sequences. Any unexpected robot...

We present an extension to the Brain Imaging Data Structure (BIDS) for motion data. Motion data is frequently recorded alongside human brain imaging and electrophysiological data. The goal of Motion-BIDS is to make motion data interoperable across different laboratories and with other data modalities in human brain and behavioral research. To this...

Efficient navigation is supported by a cognitive map of space. The hippocampus plays a key role for this map by linking multimodal sensory information with spatial memory representations. However, in human navigation studies, the full range of sensory information is often unavailable due to the stationarity of experimental setups. We investigated t...

Background Neuromuscular dysfunction is common in older adults and more pronounced in neurodegenerative diseases. In Parkinson's disease (PD), a complex set of factors often prevents the effective performance of activities of daily living that require intact and simultaneous performance of the motor and cognitive tasks. Methods The cross-sectional...

Example of data for using the code (git@github.com:BiomedicalEngineeringTechies/CLET.git) described in this article: CLET: Computation of Latencies in Event-related potential Triggers using photodiode on virtual reality apparatuses ( https://www.frontiersin.org/articles/10.3389/fnhum.2023.1223774/full). CLET is a semi-automated method to accurate...

To investigate event-related activity in human brain dynamics as measured with EEG, triggers must be incorporated to indicate the onset of events in the experimental protocol. Such triggers allow for the extraction of ERP, i.e., systematic electrophysiological responses to internal or external stimuli that must be extracted from the ongoing oscilla...

Affordances, the opportunity for action offered by the environment to an agent, are vital for meaningful behavior and exist in every interaction with the environment. Regarding its temporal mechanism, some studies suggest that affordance perception is an automated process that is independent from the visual context and bodily interaction with the e...

Affordances, the opportunity for action offered by the environment to an agent, are vital for meaningful behavior and exist in every interaction with the environment. There is an ongoing debate in the field about whether the perception of affordances is an automated process. Some studies suggest that affordance perception is an automated process th...

bold xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective . Mixed-Reality (XR) technologies promise a user experience (UX) that rivals the interactive experience with the real-world. The key facilitators in the design of such a natural UX are that the interaction has zero lag and that users experience...

Background: Neuromuscular dysfunction is common in older adults and more pronounced in neurodegenerative diseases. In Parkinson's disease (PD), a complex set of factors often prevents the effective performance of activities of daily living that require intact and simultaneous performance of the motor and cognitive tasks. Methods: The cross-sectiona...

During listening to music, the brain expects specific acoustic events based on learned musical rules. During music performance expectancy is additionally created based on motor action by linking keypresses to their sounds. We investigated EEG (Electroencephalography) signals to auditory expectancy violations in piano performance and perception. In...

Background: Neuromuscular dysfunction is common in older adults and more pronounced in neurodegenerative diseases. In Parkinson's disease (PD), a complex set of factors often prevents the effective performance of activities of daily living that require intact and simultaneous performance of the motor and cognitive tasks. Methods: The cross-sectiona...

About one of two people older than 65 years experiences age-related decline in hearing. This negatively impacts psycho-social wellbeing, economic independence, and general quality of life due to cognitive, social and physical aspects. Hearing-impairments also affect the walking performance especially when dual-tasking (DT). Thus, this study investi...

There is conflicting evidence about how interference control in healthy adults is affected by walking as compared to standing or sitting. Although the Stroop paradigm is one of the best-studied paradigms to investigate interference control, the neurodynamics associated with the Stroop task during walking have never been studied. We investigated thr...

The continuous assessment of pedestrians’ cognitive load during a naturalistic mobile map-assisted navigation task is challenging because of limited experimental control over stimulus presentation, human-map-interactions, and other participant responses. To overcome this challenge, the present study takes advantage of navigators’ spontaneous eye bl...

Understanding the changes in cognitive processing that accompany changes in posture can expand our understanding of embodied cognition and open new avenues for applications in (neuro)ergonomics. Recent studies have challenged the question of whether standing up alters cog-nitive performance. An electronic database search for randomized controlled t...

Objective. Magneto- and electroencephalography (M/EEG) measurements record a mix of signals from the brain, eyes, and muscles. These signals can be disentangled for artifact cleaning e.g. using spatial filtering techniques. However, correctly localizing and identifying these components relies on head models that so far only take brain sources into...

Immersive virtual reality (VR) allows its users to experience physical space in a non-physical world. It has developed into a powerful research tool to investigate the neural basis of human spatial navigation as an embodied experience. The task of wayfinding can be carried out by using a wide range of strategies, leading to the recruitment of vario...

The frequent use of GPS-based navigation assistance is found to negatively affect spatial learning. Displaying landmarks effectively while providing wayfinding instructions on such services could facilitate spatial learning because landmarks help navigators to structure and learn an environment by serving as cognitive anchors. However, simply addin...

Advancements in hardware technology and analysis methods allow more and more mobility in electroencephalography (EEG) experiments. Mobile Brain/Body Imaging (MoBI) studies may record various types of data such as motion or eye tracking in addition to neural activity. Although there are options available to analyze EEG data in a standardized way, th...

In our increasingly complex world, many objects in our environment do not readily afford their intended use case. From a designer’s viewpoint, the challenge then is to design for easily perceived utility. In this essay, we discuss a system to implement affordances on the user directly. We present the idea to leverage brain activity and actuation ha...

Introduction Spatial navigation is a complex cognitive function that declines in older age. Finding one’s way around in familiar and new environments is crucial to live and function independently. However, the current literature illustrates the efficacy of spatial navigation interventions in rehabilitative contexts such as pathological aging and tr...

Hearing impaired older adults exhibit a reduced walking performance under dual-task (DT) conditions compared to healthy controls or younger adults. The Mobile Brain/ Body Imaging approach (MoBI) allows for the parallel analysis of brain and body during unrestricted movement. Applying this method during different DT conditions in this target group e...

Mental rotation and mental folding are established as archetypal mental spatial transformation tasks. Yet, it is uncertain as to whether these tasks rely on a general spatial transformation mechanism or on dedicated processes. We scrutinized benchmark mental spatial transformation findings for and against the concept of a shared mechanism in two EE...

Spatial navigation is a complex multisensory process that requires the integration of visual, somatosensory and vestibular input and re-afferents from the motor system with mnemonic representations of the environment. Despite this complexity, most human adaptations of the Morris water maze (MWM, Morris et al., 1982) in spatial navigation studies ar...

Einleitung Räumliche Orientierung ist von altersbedingten Abbauprozessen betroffen. Während die Orientierungsfähigkeit in vertrauten Umgebungen erhalten bleibt, verringert sie sich in unbekannten Umgebungen [1]. Dies wird besonders beim Umzug in die stationäre Pflege relevant. Hier bleibt der Bewegungsradius von Pflegebedürftigen oft auf das eigene...

People spend a large portion of their time inside built environments. Research in neuro-architecture—the neural basis of human perception of and interaction with the surrounding architecture—promises to advance our understanding of the cognitive processes underlying this common human experience and also to inspire evidence-based architectural desig...

Objective. Neural interfaces hold significant promise to implicitly track user experience. Their application in virtual and augmented reality (VR/AR) simulations is especially favorable as it allows user assessment without breaking the immersive experience. In VR, designing immersion is one key challenge. Subjective questionnaires are the establish...

Objective: Electroencephalography (EEG) is a non-invasive technique used to record cortical neurons’ electrical activity using electrodes placed on the scalp. It has become a promising avenue for research beyond state-of-the-art EEG research that is conducted under static conditions. EEG signals are always contaminated by artifacts and other physio...

Objective: Evaluate changes in brain activity of trainees during laparoscopic surgical training from electroencephalographic (EEG) signals in an ecological scenario with few restrictions for the user. Design Longitudinal study with two follow-up measurements in the first and last session of a 4-week training with LapSim laparoscopic surgery simula...

Electroencephalography (EEG) is a non-invasive technique used to record cortical neurons' electrical activity using electrodes placed on the scalp. It has become a promising avenue for research beyond state-of-the-art EEG research that is conducted under static conditions. EEG signals are always contaminated by artifacts and other physiological sig...

In the article discussed in this chapter, the authors describe a framework of neuroaesthetics for architectural experiences that considers sensory feedback stemming from movement central for the experience of the built environment. As we move through space when experiencing architecture, our sensory impressions change, rendering the body and the br...

The augmentation of landmarks in auditory navigation instructions has been shown to improve incidental spatial knowledge acquisition during assisted navigation. Here, two driving simulator experiments are reported that replicated this effect even when adding a three-week delay between navigation and spatial tasks and varying the degree of detail in...

Landmarks support navigation and spatial learning of environments by serving as cognitive anchors. However, little research has been done to investigate how the design of landmarks on mobile maps affects cognitive processing. To address this gap, the present study utilized a within-subjects design to experimentally examine how three different landm...

Advances in Mobile Brain/Body Imaging (MoBI) technology allows for real-time measurements of human brain dynamics during every day, natural, real-life situations. This special issue Time to Move brings together a collection of experimental papers, targeted reviews and opinion articles that lay out the latest MoBI findings. A wide range of topics ac...

Neuroscience joins the long history of discussions about aesthetics in psychology, philosophy, art history, and the creative arts. In this volume, leading scholars in this nascent field reflect on the promise of neuroaesthetics to enrich our understanding of this universal yet diverse facet of human experience. The volume will inform and stimulate...

Background: Hearing impairments are associated with reduced walking performance under Dual-task (DT) conditions. Little is known about the neural representation of DT performance while walking in this target group compared to healthy controls or younger adults. Therefore, utilizing the Mobile Brain/Body Imaging approach (MoBI), we aim at gaining de...

A sedentary lifestyle in nursing home residents is often accompanied with reduced life space mobility and in turn affects satisfaction with life. One of the reasons for this may be limited ability to find one’s way around the care facility and its environment. However, spatial orientation exercises might reduce these problems if they are integrated...

The retrosplenial complex (RSC) plays a crucial role in spatial orientation by computing heading direction and translating between distinct spatial reference frames based on multi-sensory information. While invasive studies allow investigating heading computation in moving animals, established non-invasive analyses of human brain dynamics are restr...

The parallel execution of two motor tasks can lead to performance decrements in either one or both of the tasks. Age-related declines can further magnify the underlying competition for cognitive resources. However, little is known about the neural dynamics underlying motor resource allocation during dual-task walking. To better understand motor res...

The repeated use of navigation assistance systems leads to decreased processing of the environment. Previous studies demonstrated that auditory references to landmarks in navigation instructions can improve incidental spatial knowledge acquisition when driving a single route through an unfamiliar virtual environment. Based on these results, three e...

Background and Objective: The reliability of low-cost mobile systems for recording Electrocardiographic (ECG) data is mostly unknown, posing questions regarding the quality of the recorded data and the validity of the extracted physiological parameters. The present study compared the BITalino toolkit with an established medical-grade ECG system (Br...

Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which...

Coupling behavioral measures and brain imaging in naturalistic, ecological conditions is key to comprehend the neural bases of spatial navigation. This highly‐integrative function encompasses sensorimotor, cognitive, and executive processes that jointly mediate active exploration and spatial learning. However, most neuroimaging approaches in humans...

Coupling behavioral measures and brain imaging in naturalistic, ecological conditions is key to comprehend the neural bases of spatial navigation. This highly-integrative function encompasses sensorimotor, cognitive, and executive processes that jointly mediate active exploration and spatial learning. However, most neuroimaging approaches in humans...

Learning to navigate uncharted terrain is a key cognitive ability that emerges as a deeply embodied process, with eye movements and locomotion proving most useful to sample the environment. We studied healthy human participants during active spatial learning of room‐scale virtual reality (VR) mazes. In the invisible maze task participants wearing a...

Action is a medium of collecting sensory information about the environment, which in turn is shaped by architectural affordances. Affordances characterize the fit between the physical structure of the body and capacities for movement and interaction with the environment, thus relying on sensorimotor processes associated with exploring the surroundi...

Spatial navigation is one of the fundamental cognitive functions central to survival in most animals. Studies in humans investigating the neural foundations of spatial navigation traditionally use stationary, desk‐top protocols revealing the hippocampus, parahippocampal place area (PPA), and retrosplenial complex to be involved in navigation. Howev...

Conducting neuroscience research in the real world remains challenging because of movement‐ and environment‐related artifacts as well as missing control over stimulus presentation. The present study overcame these restrictions by using mobile electroencephalography (EEG) and data driven analysis approaches during a real‐world navigation task. Durin...

Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which...

The augmentation of landmarks in auditory navigation instructions had been shown to improve incidental spatial knowledge acquisition during assisted navigation. Here, two driving simulator experiments are reported that replicated this effect even when adding a three-week delay between navigation and spatial tasks and varying the degree of detail in...

Detecting and correcting incorrect body movements is an essential part of everyday interaction with one's environment. The human brain provides a monitoring system that constantly controls and adjusts our actions according to our surroundings. However, when our brain's predictions about a planned action do not match the sensory inputs resulting fro...

Background In nursing home residents, the combination of decreasing mobility and declining cognitive abilities, including spatial orientation, often leads to reduced physical activity (PA) and life-space (LS) mobility. As a consequence of sedentary behavior, there is a lack of social interaction and cognitive stimulation, resulting in low quality o...

Action is a medium of collecting sensory information about the environment, which in turn is shaped by architectural affordances. Affordances characterize the fit between the physical structure of the body and capacities for movement and interaction with the environment, thus relying on sensorimotor processes associated with exploring the surroundi...

Little is known about the neurophysiological processes underlying visual processing during active behavior and how these change over the life span. This study investigated early (P1) and later (P3) event-related potentials of the electroencephalogram associated with visual perception in older and younger adults while sitting, standing, and walking....

When walking in our natural environment, we often solve additional cognitive tasks. This increases the demand of resources needed for both the cognitive and motor systems, resulting in Cognitive‐Motor Interference (CMI). A large portion of neurophysiological investigations on CMI took place in static settings, emphasizing the experimental rigor but...

Conducting neuroscience research in the real world remains challenging because of movement-and environment-related artifacts as well as missing control over stimulus presentation. The present study demonstrated that it is possible to investigate the neuronal correlates underlying visuo-spatial information processing during real-world navigation. Us...

Distinct cognitive processing stages in mental spatial transformation tasks can be identified in oculomotor behavior. We recorded eye movements whilst participants performed a mental folding task. Gaze behaviour was analyzed to provide insights into the relationship of task difficulty, gaze proportion on each stimulus, gaze switches between stimuli...