Kirichuk Anatoly

• D.Sc.
• Head of Department at Peoples' Friendship University of Russia

Chitosan is a natural, biocompatible, biodegradable, and non-toxic polymer that has consistently garnered the attention of researchers in the development of new materials across various applications. Typically, to impart the desired properties to chitosan, chemical modification is necessary. Therefore, the development of simple and convenient metho...

Post-acidification is a common challenge for fermented dairy products, which can significantly reduce the shelf life. Herein, we developed metal nanoparticles based on chitosan and Mn(II) ions that can slow down post-acidification and stimulate the milk fermentation process. By systematic characterization and optimization using dynamic and electrop...

Introduction. The most popular education in Russian higher education institutions is among applicants from Central Asian countries, including Ka-zakhstan, Tajikistan, Turkmenistan, Uzbekistan and Kyrgyzstan. Students from this region make up more than half of all foreign citizens studying in Russian universities. Changed environmental conditions le...

Introduction. In previous years, RUDN University conducted a comparative analysis of the ionomic profiles of first-year students from Africa, Central Asia, Latin America, the Middle East, China and others, but a comparison of the elemental status of first-year RUDN University students from the Middle East and the Moscow region has not been describe...

Introduction. The most popular education in Russian higher education institutions is enjoyed by immigrants from Central Asian countries, including Kazakhstan, Tajikistan, Turkmenistan, Uzbekistan and Kyrgyzstan. They account for more than half of all foreign citizens studying in Russian universities. Changed environmental conditions lead to the dev...

A new pyridine-fused seleno­diazo­lium salt, 3-(phenyl­selan­yl)[1,2,4]selena­diazolo[4,5-a]pyridin-4-ylium chloride di­chloro­methane 0.352-solvate, C12H9N2Se2⁺·Cl⁻·0.352CH2Cl2, was obtained from the reaction between 2-pyridyl­selenenyl chloride and phenyl­seleno­cyanate. Single-crystal structural analysis revealed the presence of C—H⋯N, C—H⋯Cl⁻,...

The study was performed to determine Selenium level in a first year foreign students' biosubstrates who came for an education to Peoples' Friendship University of Russia - RUDN University. The number of students who participated in the study was in total 583 and contained of students from North and Tropical Africa, Latin America, the Near and Middl...

The synthesis and structural characterization of α-haloalkyl-substituted pyridinium-fused 1,2,4-selenadiazoles with various counterions is reported herein, demonstrating a strategy for directed supramolecular dimerization in the solid state. The compounds were obtained through a recently discovered 1,3-dipolar cycloaddition reaction between nitrile...

The objective of the present narrative review was to synthesize existing clinical and epidemiological findings linking manganese (Mn) exposure biomarkers to autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), and to discuss key pathophysiological mechanisms of neurodevelopmental disorders that may be affected by this...

One of the conditions for the normal functioning of a living organism is a constant supply of clean and high-quality drinking water. This is also true for the population. Therefore, during the study, the characteristics of the content of heavy metals in drinking water in the south of Central Siberia were studied. During the work, the following task...

In this study, Rhodamine B-containing chitosan-based films were prepared and characterized using their mechanical, photophysical, and antibacterial properties. The films were synthesized using the casting method and their mechanical properties, such as tensile strength and elongation at break, were found to be dependent on the chemical composition...

As it is known from numerous scientific data, human health is mainly influenced by the environment and food. As is known, the concentration of chemical elements in hair reflects the ecological state of the territory, which is formed under the influence of natural and/or anthropotechnogenic factors. The formation of causal relationships between the...

Today, studies of the content and effect of chemical elements on the body are relevant. It is especially important to conduct such research in areas exposed to negative environmental factors (for example, industrial pollution of the atmosphere, soil pollution with chemicals, etc.). At the same time, fluctuations in the content of trace elements in...

The analysis of the scientific literature on the subject of bioremediation in Latin America countries shows that due to the excessive and uncontrolled use of pesticides in agriculture, there are negative impacts on the environment, mainly on soil and water, as well as on human health. However, through processes such as bioremediation, which utilize...

The content of some chemical elements that support immune responses (selenium, zinc, iron, iodine) was analyzed among representatives of the ethno-demographic groups of the North-East of Russia - natives (Chukchi, Koryaks, Evens), mestizos, and newcomers. A potential risk group for the development of hyposelenoses is the Koryak ethnic group. The mi...

Contamination soils with heavy metals is a problem with high interest, because contamination with heavy metals affect food chains and human health by intake and accumulation in living beings. Although all of these methods not quite effective for recovering contaminated environments, however they are still good options for recovering contaminated so...

This comprehensive review illuminates the various methods of chitosan extraction, its antibacterial properties, and its multifarious applications in diverse sectors. We delve into chemical, physical, biological, hybrid, and green extraction techniques, each of which presents unique advantages and disadvantages. The choice of method is dictated by m...

In this work, we focused on synthesizing and assessing novel chitosan-based antibacterial polymers and their nanoparticles by incorporating benzothiazole substituents. The growing resistance to antibiotics has necessitated the search for alternative antimicrobial compounds. This study aimed to synthesize and evaluate chitosan-based polymers and nan...

In this study, we elaborated new chitosan-based films reinforced by iron(III)-containing chitosan nanoparticles Fe(III)-CS-NPs at different concentrations. We found that the optimum concentration of Fe(III)-CS-NPs for the improvement of antibacterial and mechanical properties of the films was 10% (σb = ca. 8.8 N/mm2, εb = ca. 41%, inhibition zone f...

Antibacterial chitosan films, versatile and eco-friendly materials, have garnered significant attention in both the food industry and medicine due to their unique properties, including biodegradability, biocompatibility, and antimicrobial activity. This review delves into the various types of chitosan films and their distinct applications. The cate...

In this study, we prepared chitosan/Fe(III)/deferoxamine nanoparticles with unimodal size distribution (hydrodynamic diameter ca. 250 nm, zeta potential ca. 32 mV). The elaborated nanoparticles are characterized by outstanding in vitro and in vivo antibacterial activity, which exceeds even that of commercial antibiotics ampicillin and gentamicin. M...

Microorganisms, fermentation processes, and the resultant metabolic products are a key driving force in biotechnology and, in particular, in food biotechnology. The quantity and/or quality of final manufactured food products are directly related to the efficiency of the metabolic processes of producer microorganisms. Food BioTech companies are natu...

In this study, new Cu(II)/chitosan-based systems were designed via (i) the treatment of chitosan with sodium sulfate (1a) or sodium acetate (1b); (ii) the coating of 1a or 2a with a sodium hyaluronate layer (2a and 2b, correspondingly); (iii) the treatment of a cholesterol–chitosan conjugate with sodium sulfate (3a) or sodium acetate (3b); and (iv)...

Ciprofloxacin is one of the most effective antibiotics, but it is characterized by a range of side effects. Elaboration of drug-releasing systems which allow to diminish toxicity of ciprofloxacin is a challenging task in medicinal chemistry. The current study is focused on development of new ciprofloxacin releasing systems (CRS). We found that ultr...

Ultrasound-mediated reaction of chitosan with ciprofloxacin in the presence of N,N'-dicyclohexylcarbodiimide in water gives the chitosan–ciprofloxacin conjugates of carboxamide type. The conjugates show a mediate antibacterial effect and reduced cytotoxicity.

A practical method for the synthesis of 2-selenoxo-1,2,3,4-tetrahydro-4-quinazolinone was reported. The latter compounds were found to undergo facile oxidation with H2O2 into corresponding diselenides. Novel organoselenium derivatives were characterized by the ¹H, ⁷⁷Se, and ¹³C NMR spectroscopies, high-resolution electrospray ionization mass spectr...

The synthesis and structural characterization of a series of supramolecular complexes of bicyclic cationic pyridine-fused 1,2,4-selenodiazoles with various anions is reported. The binding of trifluoroacetate, tetrachloroaurate, tetraphenylborate, perrhenate, and pertechnetate anions in the solid state is regarded. All the anions interact with selen...

Novel triarylazoimidazoles containing strong electron donors (p-NEt2) or acceptors (p-NO2) by the azoaryl group, and their group 12 metal complexes were synthesized and fully characterized, including X-ray analysis for several complexes. Novel complexes exhibit red photo-luminescence emission (Φ up to 0.21) in a solution. Moreover, the antibacteria...

Ultrasonic approach to the synthesis of the first selenium-containing derivatives of chitin and chitosan has been developed. The synthetic procedure is simple, provides high yields, does not require harsh conditions, and uses water as the reaction medium. The elaborated chitin and chitosan derivatives and their based nanoparticles are non-toxic and...

Mild and ‘green’ ultrasound-assisted reaction of chitin with 3-(chloromethyl)[1,2,4]selenadiazolo[4,5-a]pyridin-4-ium bromide in water affords novel selenium-containing cationic chitin derivatives. The thus obtained chitin derivatives are water soluble and are characterized by high in vitro antifungal activity comparable with conventional antifunga...

Gold(I) isocyanide complexes featuring Au···Au interactions attract considerable attention because of their tunable photophysical properties. Although the synthetic exploration of isocyanide gold(I) complexes seems reasonable, their structural diversity is mainly limited to linear gold(I) derivatives. The synthesis and structural characterization o...

Цель исследования – выявление особенностей элементного статуса студентов первого курса из различных климатогеографических регионов мира, прибывших на обучение в Российскую Федерацию. Материалы и методы. Анализ исследуемых биологических образцов (волос и мочи) студентов из Российского университета дружбы народов (РУДН) выполнен методом масс-спектром...

The results of a study on the content of toxic metals in the hair of first-year students of the Peoples Friendship University of Russia who arrived for training from various climatogeographic regions of the world are presented. The research involved first-year students from Africa, Latin America, the Near and Middle East, and Southeast Asia. A grou...

The synthesis of 2-pyridyltellurenyl bromide via Br2 oxidative cleavage of the Te–Te bond of dipyridylditelluride is reported. Single-crystal X-ray diffraction analysis of 2-pyridyltellurenyl bromide demonstrated that the Te atom of 2-pyridyltellurenyl bromide was involved in four different noncovalent contacts: Te⋯Te interactions, two Te⋯Br ChB, a...

Several metal nanoparticles have been developed for medical application. While all have their benefits, gold nanoparticles (AuNPs) are ideal in cancer therapy and diagnosis as they are chemically inert and minimally toxic. Several studies have shown the potential of AuNPs in the therapeutic field, as photosensitizing agents in sonochemical and phot...

Correction for ‘Novel cationic 1,2,4-selenadiazoles: synthesis via addition of 2-pyridylselenyl halides to unactivated nitriles, structures and four-center Se⋯N contacts’ by Victor N. Khrustalev et al. , Dalton Trans. , 2021, 50 , 10689–10691, DOI: 10.1039/D1DT01322J.

2-Pyridylselenyl halides undergo facile coupling with a triple CN bond of unactivated nitriles. Unprecedented heterocyclization allowed the preparation of novel class of cationic 1,2,4-selenadiazoles in remarkably high yields. Cationic 1,2,4-selenadiazoles...

The objective of the study is investigation of the impact of magnesium on psycho-emotional stress and functional activity of the cardiovascular system in foreign male students of African origin. A total of 33 male first course students were involved in the study. The examinees were supplemented with 150 mg/day of magnesium. Evaluation of serum and...

Introduction. The objective of the study is an assessment of dietary iron, iodine, and zinc content in school dinners in Tajik schoolchildren, as well as the influence of the use of fortified products supplied by the UN World Food Programme. Material and methods. The investigation is performed in two types of schools located in Penjikent and Ayni r...

The objective of the present study was to assess the markers of arsenic, cadmium, mercury, and lead exposure in first-year RUDN University students of different geographic origins. A total of 274 first-year students of the RUDN University originating from Russia (n = 65), Asia (n = 57), Middle East (n = 84), Africa (n = 40), and Latin America (n =...

The aim of the study was to perform a comparative analysis of hair content of toxic metal in foreign students originating from different regions.Material and methods. An examination of first-year students of the RUDN University originating from Russia, Asia, the Middle East, Africa, and Latin America was performed in the study. Assessment of hair a...

The objective of the study was to assess selenium and other elements levels in Indian Roti bread from Se-rich maize and rice using inductively coupled plasma mass-spectrometry. Se levels in Roti bread from Se-rich maize and rice exceeded those in the control samples by a factor of more than 594 and 156, respectively. Using Se-enriched maize increas...

The objective of the present study was to assess hair and urinary levels of cobalt (Co) and manganese (Mn) in foreign students of RUDN University in comparison to the Russian counterparts. A total of 272 first-year students of the RUDN University originating from Russia, Asia, Middle East, Africa, and Latin America were enrolled in the study. Evalu...

Представлены результаты изучения влияния неблагоприятных факторов внешней среды и социальных условий московского мегаполиса на характер адаптационных реакций студентов из различных стран мира. Проведенные исследования показали, что студенты из стран Латинской Америки, приехавшие на учебу в Москву, имеют значительно больший процент неблагоприятных а...

The purpose of this study was to study the elemental status of first-year students of the Russian University of Friendship of Peoples who arrived to study from various climatogeographic regions of the world. Studies have shown that first-year students who came to study from different climatogeographic regions of the world are characterized by signi...

The aim of the study was to study the relationship between the level of essential trace elements and the functional state of the cardiovascular system (CVS) in freshmen from foreign countries compared with freshmen from Russia (control group). The CVS study was conducted by the AngioScan-01 hardware-software complex (AIC). The level of essential el...

The objective of the present study was to assess the levels of Se, as well as other essential and toxic trace elements in wheat grains and traditional Roti-bread from whole-grain flour in a seleniferous area of Punjab (India) using inductively-coupled plasma mass-spectrometry. Wheat grain and bread selenium levels originating from seleniferous area...

Background: The objective of the study was to assess hair trace element and mineral content in children undergoing WFP UN and the governmental programs of school nutrition in Tajikistan. Methods: WFP program included provision or wheat flour fortified with micronutrients including Fe and Zn, and iodized salt, whereas within the governmental progra...

The objective of the present study was investigation of the selenium (Se) levels in environmental samples, main consumed food products, as well as human hair in the areas of the Orenburg region. Se levels in the environmental objects (water, soil, wheat), frequently consumed food products (wheat bread, ryebread, beef, pork, chicken, milk, cottage c...

The identification of causation and incidence between the impact of environmental factors and changes in the human adaptive potential is one of the urgent tasks of ecological and biological monitoring. The aim: a comparative assessment of the state activity of functional systems, imbalance and the nature of adaptation reactions of the body in forei...