Kiran Vema

Kiran Vema
Mohan Babu University

Doctorate in Pharmaceutical Sciences

About

18
Publications
2,594
Reads
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161
Citations
Additional affiliations
February 2010 - present
Sree Chaitanya Institute of Pharmaceutical Sciences, Karimnagar
Position
  • Professor (Associate)
Education
December 2013
Jawaharlal Nehru Technological University Anantapur
Field of study
  • pharmaceutical sciences

Publications

Publications (18)
Article
Full-text available
A cost-effective and innovative reverse phase high performance liquid chromatography (RP-HPLC) technique has been devised to accurately and precisely measure the quantity of Atomoxetine Hydrochloride in both large quantities and solid dosage forms. The separation process was conducted using an Xterra RP 18 column with dimensions of 250 mm × 4.6 mm...
Article
Full-text available
The present study deals with the antidiabetic and antihyperlipidemic activities of Murraya koenigii, commonly known as curry leaves, extract on STZ-induced diabetic rats. The given dose of the extract to the rats in this study was 500 mg/kg body weight for 37 days and then estimated its effects on blood glucose and HbA1c levels and lipid profile. R...
Article
Full-text available
This study aimed to develop and characterize transdermal patches for rucaparib using a Box-Behnken design (BBD), evaluating drug permeation at 8, 12, and 24 hours, with optimization through Design Expert software. The patches were formulated with HPMC K15, ethyl cellulose, and PVP K30. The physicochemical properties and drug infusion were tested an...
Article
Full-text available
Prasugrel hydrochloride functions as an agent that inhibits platelet activity and prevents the formation of blood clots. The mortality rate attributed to thrombosis has been increasing, therefore highlighting the need to develop methodologies for the evaluation of pharmaceutical interventions. The objective of this study was to develop a Prasug...
Article
Full-text available
The present work was designed and characterized nicardipine solid lipid nano-particulars and formulated into capsule. The formulation was evaluated and stability also as per the specified limits. The nanoparticles were prepared by solid hydrophilic adsorbents. The obtained ratio of 1:1:1:2 of drugs, soy PC, DMPC, and labrasol shows the highest diss...
Research
Full-text available
A cost-effective and innovative reverse phase high performance liquid chromatography (RP-HPLC) technique has been devised to accurately and precisely measure the quantity of Atomoxetine Hydrochloride in both large quantities and solid dosage forms. The separation process was conducted using an Xterra RP 18 column with dimensions of 250 mm × 4.6 mm...
Article
Full-text available
This study introduces a novel approach involving the formulation of controlled-release ketorolac gels, which have demonstrated efficacy when administered topically. The investigation delves into the potential of these gels as carriers for the delivery of ketorolac. The release pattern of the drug in vitro, across all formulations, followed a diffus...
Article
Full-text available
Orally Disintegration Tablet (ODTs) are solid dosage forms containing active pharmaceutical ingredient (API) which disintegrate rapidly, usually less than 60 seconds without the need of water when placed on the tongue. Metoprolol, which is practically water insoluble, shows low bioavailability. weighed 100mg Propranolol was dissolved in 100ml of me...
Chapter
Full-text available
In a daily life, wounds on skin and tissues due to several reasons are quite common and hence the pathophysiology of wound healing is extensively reported in the literature. The research focus on wound dressings has also been tremendously enhanced due to its significant commercial market value. Numerous biopolymers have already been investigated as...
Chapter
Full-text available
Alginates are the biodegradable natural biopolymeric group of alginic acid salts extensively exploited in the designing of various pharmaceutical dosage forms to deliver drugs. Alginates have also been used by the dental practitioners for over years as dental biomaterial. Many successful attempts have been accomplished for the use of sodium alginat...
Article
Full-text available
Aim Present study aims at preparation and evaluation of buccal patches for combination drugs for Paracetamol and tramadol which are used in pain management. The patches were developed by using HPMC, Carbopol as polymers. Such dosage forms helps in repeated administration of dosage forms and patient acceptance. Method Buccal Patches of combination d...
Article
Present study describes the development of a new formulation of levonorgestrel and ethinylestradiol based on double emulsion-solvent evaporation technique using poly(epsilon-caprolactone) (PCL) as biodegradable polymer. The effect of polymer concentration on microspheres and entrapment of drug into microspheres were studied. PCL was selected becaus...

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