Kholoud Kahime

Kholoud Kahime
Cadi Ayyad University | UCAM · School of Technology

PhD
Professor Researcher

About

48
Publications
10,680
Reads
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485
Citations

Publications

Publications (48)
Chapter
Full-text available
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder of great concern of which no proven neuroprotective or neurorestorative therapies are available. It is characterized mainly by the degeneration of dopamine (DA) producing neurons in the substantia nigra (SN) pars compacta (SNpc) resulting in nigrostriatal pathway dysregul...
Chapter
The purpose of this chapter is to examine the evidence of a relationship between climatic changes and snake species distribution in relation with the snakebites risk increment against human populations. The global climatic change is a key factor leading to snake species behavioral changes mainly because of the rise of temperature. The variety of ve...
Article
Full-text available
The newly emerged 2019 coronavirus disease (COVID-19) has urged scientific and medical communities to focus on epidemiology, pathophysiology, and treatment of SARS-CoV-2. Indeed, little is known about the virus causing this severe acute respiratory syndrome pandemic, coronavirus (SARS-CoV-2). Data already collected on viruses belonging to the coron...
Chapter
In December 2019, the world saw the appearance of a severe acute respiratory syndrome, SARS-CoV-2, in Wuhan. The virus originated in bats and was transmitted to humans. The number of cases started increasing exponentially. According to the World Health Organization, the massive migration of Chinese during the Chinese New Year fuelled the epidemic....
Chapter
As a result of increased frequency and intensity of heat waves, increased floods and droughts, change in climate will affect biological, physical, and chemical components of water through different paths thus enhancing the risk of waterborne diseases. Identifying the role of weather in waterborne infection is a priority public health research issue...
Chapter
The incidence of emergence diseases including vector borne diseases, water diseases, and some physiologic impairment is considered sensitive to climate. Malaria, leishmaniasis, dengue, and viral encephalitis are among those diseases most influenced by climate. Variation in the incidence of vector borne diseases is associated with extreme weather ev...
Chapter
Every year, more than 1 million cases of scorpion envenomation are reported worldwide. Scorpions are thermophilic organisms. They are sensitive to weather and climate conditions, in such a way the ongoing trends of increasing temperature and more variable weather could lead to scorpionism spreading. There has been considerable debate as to whether...
Chapter
Climate change has an important impact on the environment. As it degrades the quality of water, soil, and area, it also spreads the distribution of many toxic elements, specifically heavy metals and pesticides. The impact of climate change on contamination with heavy metals and pesticides has been well investigated and discussed. The influence of t...
Chapter
Malaria is a mosquito-borne infectious disease caused by obligate intraerythrocytic protozoa of the genus Plasmodium. As one of the most devastating global health issues, malaria is a sensitive disease to weather and climate conditions, in such a way the ongoing trends of increasing temperature and more variable weather could lead to malaria transm...
Chapter
Moroccan ecosystems are considered endangered due to climate change that affects directly or indirectly different key features (biodiversity, snow cover, run-off processes, and water availability). The chapter describes the strategy for achieving collaboration between natural and social scientists, stakeholders, decision makers, and other societal...
Article
Full-text available
The global burden of viral infection, especially the current pandemics of SARS-CoV-2, HIV/AIDS, and hepatitis, is a very risky one. Additionally, HCV expresses the necessity for antiviral therapeutic elements. Venoms are known to contain an array of bioactive peptides that are commonly used in the treatment of various medical issues. Several peptid...
Chapter
Full-text available
Coronaviruses are a large family of viruses that usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. They were named according to the shape of glycoprotein spikes present on the viral surface and resembling to the solar corona. The first coronaviruses identified in human were HCoV 229E and the HCoV OC43, known al...
Chapter
Full-text available
This chapter presents a literature review on the effect of environmental changes factors exposure in the etiology of Alzheimer's and Parkinson's diseases. The use of pesticides is more intense and somehow erratic as it aims to face climate change consequences like drought and water scarcity. The rural population is getting to be more vulnerable to...
Article
Full-text available
In Morocco, cutaneous and visceral leishmaniases represent a public health concern. In this opinion paper, we propose to highlight chosen elements that have governed the drastic increase in the incidence of leishmaniases recorded in Morocco during the period between 1990 to 2010 in order to guide the prediction of the expansion of diseases and epid...
Presentation
De plus en plus mondialisé, financiarisé et interconnecté, le monde d’aujourd’hui dans lequel évoluent nos organisations et nos territoires nous invite à acter le changement et à réinventer de nouvelles pratiques pour répondre à des problématiques de plus en plus complexes. Émergent alors de nombreux discours sur le rôle de la créativité (Parmentie...
Presentation
De plus en plus mondialisé, financiarisé et interconnecté, le monde d’aujourd’hui dans lequel évoluent nos organisations et nos territoires nous invite à acter le changement et à réinventer de nouvelles pratiques pour répondre à des problématiques de plus en plus complexes. Émergent alors de nombreux discours sur le rôle de la créativité (Parmentie...
Chapter
Full-text available
Malaria is a mosquito-borne infectious disease caused by obligate intraerythrocytic protozoa of the genus Plasmodium. As one of the most devastating global health issues, malaria is a sensitive disease to weather and climate conditions, in such a way the ongoing trends of increasing temperature and more variable weather could lead to malaria transm...
Book
Full-text available
The faster climate change affects the globe, the faster individuals will see the negative consequences, which include the decline of general human health. Comprehension of all climate change-related etiologies is essential to understanding the importance of global environmental stability. The Handbook of Research on Global Environmental Changes an...
Book
Full-text available
The purpose of this chapter is to examine the evidence of a relationship between climatic changes and snake species distribution in relation with the snakebites risk increment against human populations. The global climatic change is a key factor leading to snake species behavioral changes mainly because of the rise of temperature. The variety of ve...
Chapter
Every year, more than 1 million cases of scorpion envenomation are reported worldwide. Scorpions are thermophilic organisms. They are sensitive to weather and climate conditions, in such a way the ongoing trends of increasing temperature and more variable weather could lead to scorpionism spreading. There has been considerable debate as to whether...
Chapter
Leishmaniasis is a complex disease comprised of multiple organisms in association. Each of these organisms responds differently to external factors. The environmental and socioeconomic associations contribute to the dynamics and emergence of leishmaniasis across the globe. Ecological dynamics of the vector-parasite-host system of leishmaniasis infl...
Chapter
The incidence of emergence diseases including vector borne diseases, water diseases, and some physi-ologic impairment is considered sensitive to climate. Malaria, leishmaniasis, dengue, and viral encepha-litis are among those diseases most influenced by climate. Variation in the incidence of vector borne diseases is associated with extreme weather...
Chapter
Full-text available
This chapter presents a literature review on the effect of environmental changes factors exposure in the etiology of Alzheimer's and Parkinson's diseases. The use of pesticides is more intense and somehow erratic as it aims to face climate change consequences like drought and water scarcity. The rural population is getting to be more vulnerable to...
Chapter
Full-text available
Climate change has an important impact on the environment. As it degrades the quality of water, soil, and area, it also spreads the distribution of many toxic elements, specifically heavy metals and pesticides. The impact of climate change on contamination with heavy metals and pesticides has been well investigated and discussed. The influence of t...
Chapter
As a result of increased frequency and intensity of heat waves, increased floods and droughts, change in climate will affect biological, physical, and chemical components of water through different paths thus enhancing the risk of waterborne diseases. Identifying the role of weather in waterborne infection is a priority public health research issue...
Article
Full-text available
The proliferation of vector-borne diseases are predicted to increase in a changing climate and Leishmaniases, as a vector-borne diseases, are re-emerging diseases in several regions of the world. In Morocco, during the last decade, a sharp increase in cutaneous leishmaniases cases has been reported. Nevertheless, in Morocco, leishmaniases are a maj...
Article
The ecological, environmental and socioeconomic importance of the Marrakech-Tensift-Al Haouz region in Morocco faces several challenges to climate change. This region suffers mainly from water scarcity and unsustainable management of water resources. Nonetheless, the institutional and technological solutions dedicated are insufficient. Thus, the de...
Article
Full-text available
Human visceral leishmaniasis one of the seven most neglected tropical diseases in the world. In Morocco, HVL is widespread in all regions; but it is more common in the northern part with sporadic cases observed in the South. During the period between 2004 and 2013, the most affected Moroccan provinces were Taounate province, with 220 cases (16.09%...
Chapter
Africa, a continent at the dawn of its development, is therefore the least polluting one. The economic and social well-being of present and future African populations is heavily dependent on good governance and regionalization based on efficiency to meet specific needs and also on mutual assistance. On the other hand, good environmental policy will...
Chapter
Human societies are rapidly increasing in size, driving with them the level of appropriation of Earth’s resources, including land use. Today, human influence has reached global proportions and has altered ecosystems with consequences for local and regional climates. These changes in climates often alter the biosphere’s ecosystem services and social...
Chapter
The world is experiencing today a period of deep change whose pace is on growing. It lives in a period of instability heralding the advent of a society marked by the uncertainty and the turbulence. Currently, the consideration of environment and the necessity to react quickly are required. The importance of those elements is linked to the subjectiv...
Book
Le changement climatique est maintenant reconnu comme un risqué sérieux pour le développement et peut même neutraliser les efforts déployés dans ce domaine dans le passé et le futur aussi. Dans les pays où le développement dépend des ressources naturelles et des facteurs climatiques, on prévoit que le changement climatique aura des impacts négatifs...
Chapter
Climate change is expected to affect the distribution, prevalence and life cycle of several infectious diseases. This scenario is relevant to Morocco since the country is considered by many IPCC assessments reports as a climate change hotspot with a high vulnerability to many expected impacts. Given this existing vulnerability, this chapter aims to...
Chapter
Climate change is expected to affect the distribution, prevalence and life cycle of several infectious diseases. This scenario is relevant to Morocco since the country is considered by many IPCC assessments reports as a climate change hotspot with a high vulnerability to many expected impacts. Given this existing vulnerability, this chapter aims to...
Chapter
Full-text available
Climate change is expected to affect the distribution, prevalence and life cycle ofseveral infectious diseases. This scenario is relevant to Morocco since the countryis considered by many IPCC assessments reports as a climate change hotspot witha high vulnerability to many expected impacts. Given this existing vulnerability, thischapter aims to hig...
Article
Full-text available
It is predicted that the life cycle, incidence and spread of several infectious diseases will be increasingly and adversely affected by climate change. Morocco, designated as an area of significant impact by numerous reports of Intergovernmental Panel on Climate Change, is notably susceptible to such drastic climate-related health consequences. The...
Article
Full-text available
Leishmania infantum (Kinetoplastida: Trypanosomatidae) infection is transmitted by an infected female sand fly (Diptera: Psychodidae, Phlebotominae) of the subgenus Larroussius: Phlebotomus ariasi, Phlebotomus perniciosus, and Phlebotomus longicuspis in the Mediterranean basin. In Morocco, the vectorial role of P. ariasi was demonstrated, while tha...
Chapter
Full-text available
Human societies are rapidly increasing in size, driving with them the level of appropriation of Earth's resources including land use. Today human influence has reached global proportions and has altered local ecosystem services with consequences for local and regional climates. These changes in climates often alter the biosphere's ecosystem service...
Article
Full-text available
Background: Cutaneous Leishmaniasis (CL) is one of the most neglected tropical diseases in Morocco. Leishmania major and L. tropica are the main culprits identified in all endemic foci across the country. These two etiological agents are transmitted by Phlebotomus papatasi and P. sergenti, the two most prevalent sand fly species in Morocco. Previo...
Article
Phlebotomine sand flies (Diptera: Psychodidae, Phlebotominae) are of considerable public health importance because of their ability to transmit several human parasites, mainly as vectors of Leishmania spp. Over the past decade, the epidemiological situation of cutaneous leishmaniasis (CL) has significantly increased with its geographic expansion to...
Article
Full-text available
Objective: To describe and compare the epidemiological features of anthroponotic cutaneous leishmaniasis (ACL) caused by Leishmania tropica, and zoonotic cutaneous leishmaniasis (ZCL) due to Leishmania major in Morocco. Methods: We performed a retrospective study of ZCL and ACL cases reported during the last ten years in Morocco (2004–2013). Epidem...
Article
Full-text available
Commensal rodents as well as wild ones may present a potential risk to public health. They are reservoirs or vectors of many pathogens. This review provides an update on their epidemiological role in the spread of leishmaniasis in Morocco. In Morocco, the order Rodentia is represented by 7 families and 32 species of which Rattus norvegicus, Psammom...
Article
Visceral and cutaneous leishmaniases are the main endemic vector-born diseases in Morocco. Human Visceral Leishmaniasis (HVL), by Leishmania infantum, currently presents a significant health problem throughout the country and may constitute factor for death, especially among children with less than 15 years old. In the past, HVL has been basically...
Article
Full-text available
The Bactrocera oleae Rossi fly is the most important olive pest. It is of major economic importance in the olive production area of Essaouira, where weather conditions are optimal for the conduct of the various stages of its life cycle. The lack of phytosanitary treatments worsens this situation. The development of the larval stages and different g...
Article
Full-text available
Leishmaniasis, a highly neglected disease, currently presents a significant health problem throughout Africa. This review presents a summarized analysis of its epidemiology in Moroccan context, a Mediterranean location in which leishmaniasis is prevalent and where both cutaneous and visceral leishmaniasis have been reported. This study aims to dete...
Article
Full-text available
Shifts in surface climate may have changed the dynamic of zoonotic cutaneous leishmaniasis (ZCL) in the pre-Saharan zones of North Africa. Caused by Leishmania major, this form multiplies in the body of rodents serving as reservoirs of the disease. The parasite is then transmitted to human hosts by the bite of a Phlebotomine sand fly (Diptera: Psyc...

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