Khodabakhsh Niknam

Khodabakhsh Niknam
Persian Gulf University | PGU · Department of Chemistry

Prof.

About

154
Publications
21,851
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3,812
Citations
Citations since 2016
18 Research Items
1385 Citations
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200

Publications

Publications (154)
Article
Full-text available
The phosphine-free palladium-based catalytic system Pd(OAC)2/DABCO has been developed for the carbonylative transformations of aryl halides with formic acid. The DABCO acts as a base as well as N-donor ligand to coordinate with metal ions and stabilize Pd-catalytic sites during the reaction process. Using DCC as the activator of formic acid and PEG...
Article
A series of new quinazoline derivatives were designed and synthesized via a one-pot condensation reaction between isatoic anhydride and aromatic aldehydes with anilines using aluminum sulfate as a catalyst in refluxing ethanol. Their structures were confirmed by their physical, IR, 1H NMR, 13C NMR, and mass spectroscopy data and evaluated for some bi...
Article
Recent developments in nanofluids indicate that the addition of nanoparticles to water-based drilling muds can alleviate many drilling problems, including wellbore instability, lost circulation, torque and drag force, differential pipe sticking, and low drilling rates. In this study, the addition of hydrophilic Gilsonite nanoparticles (HGNs) to wat...
Article
Full-text available
The use of environmentally friendly methods is one of the new approaches in combating pathogens in aquaculture systems. The purpose of this research was the possibility evaluation of indirect use of Ag-NPs-coated porous ceramic in water filtration of culture system of shrimp post-larvae to control Vibrio harveyi. In this study, Ag-NPs-coated filter...
Article
In this study, hydrophilic gilsonite fine particles were produced by reaction of natural gilsonite with a mixture of sulfuric acid and nitric acid followed by a planetary ball mill process. The hydrophilic gilsonite was characterized using FTIR, XRD, FE-SEM, DLS, elemental analysis, and mass spectroscopy. All experiments showed that the characteris...
Conference Paper
Full-text available
Gilsonite is a natural fossil resource; gilsonite or natural bitumen is also known as natural asphalt. In this study, natural gilsonite becomes hydrophilic by its reaction to a mixture of sulfuric acid and nitric acid and then, its size reduced to nanoscale using planetary ball mill process under argon atmosphere. The hydrophilic gilsonite was char...
Article
2-(3-indolyl) - 4,5 di phynyl imidazole(IDPI), was used as a complexing agent in cloud point extraction for the first time and applied for selective pre-concentration of trace amounts of Aluminium. The method is based on the extraction of Aluminium at pH 3.5 by using non-ionic surfactant T-X114 and 2-(3-indolyl) - 4,5 di phenyl imidazole.(IDPI) as...
Article
Full-text available
Silver nanoparticles are the most important nanomaterials for antibacterial uses and are famous for their strong inhibitory and antibacterial effects. In recent years, extensive studies have been undertaken on the use of antimicrobial properties of silver, incorporated within aquaculture industry. To evaluate the scientific basis for the use of the...
Article
Full-text available
Solvent-free room temperature synthesis of tert-butyl peresters was achieved via copper-catalyzed oxidative-coupling of benzyl cyanides with tert-butyl hydroperoxide in short reaction times. Various derivatives of tert-butyl peresters were synthesized by this pathway in good to excellent yields. Further investigation revealed that the above-mention...
Article
A novel series of dihydropyrrol-2-one compounds bearing sulfonamide groups were synthesized and assayed for in vitro antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Streptococcus epidermidis bacteria. Antibacterial results showed that most of the compounds exhibited the antibacterial activity agai...
Article
Some new 2,3,4,5-tetrasubstituted pyrroles were synthesized via three-component condensation reaction of benzoin derivatives, 1,3-dicarbonyl compounds, and ammonium acetate using acidic Al2O3 as an efficient and reusable heterogeneous catalyst in refluxing ethanol in high yields. Also, acidic alumina was catalyzed 1,4-dihydro-tetraarylpyrazines by...
Article
Full-text available
Background: Nanotechnology is a field of applied science and technology covering a broad range of topics. Use of nanotechnology and especially silver nanoparticles in control of bacterial diseases and infections has been studied in the recent years. The aim of the present study was to investigate the in vitro antibacterial effect of filter media co...
Article
Silica-bonded ionic liquids is employed as a recyclable catalyst for the synthesis of spiro[indoline-3,4′-pyrano[2,3-c]pyrazoles] via one-pot condensation reaction of isatin, activated methylene reagents, and 3-methyl-l-phenyl-5-pyrazolone in refluxing aqueous medium in good to high yields. Also, these silica-bonded ionic liquids were used as catal...
Article
Silica-bonded S-sulfonic acid is employed as a recyclable catalyst for the synthesis of naphthoxazinone derivatives from the reaction of ß-naphthol, aromatic aldehydes and urea at 150°C under solvent-free conditions. The heterogeneous catalyst was recycled for five runs after the reaction of ß-naphthol, benzaldehyde and urea without losing its cata...
Article
Silica-bonded N-propylpiperazine sodium N-propionate is employed as a recyclable heterogeneous solid base catalyst for the synthesis of benzopyrano[2,3-d]pyrimidines through one-pot condensation reaction of salicylaldehydes, malononitrile, and secondary amines at room temperature under solvent-free conditions. The catalyst could be recycled several...
Article
Full-text available
A sensitive and selective solid phase extraction procedure for the determination of traces of Cd(II), Zn(II) and Ag(I) ions has been developed. An alumina-sodium dodecyl sulfate (SDS) coated on with 2,3 Di Hydro 2,3 paratolyl Qinazoline (1 H)- 4 one (DPTQO). The influences of the analytical parameters including pH and sample volume were investigate...
Article
Silica-bonded n-propyldiethylenetriamine sulfamic acid (SBPDSA) was found as an efficient solid acid for the synthesis of coumarins. Coumarin derivatives were obtained viathe Pechmann condensation reaction of phenols and β-keto-esters at 80 o C under solvent-free conditions. Also, biscoumarins were obtained viathe condensation of aldehydes and 4-hy...
Article
Full-text available
Abstract Silica-bonded N-propyltriethylenetetramine was used as a heterogeneous solid base catalyst for the synthesis of spirooxindole pyrimidines by a one-pot condensation reaction of isatin, activated methylene reagent, and barbituric acid or thiobarbituric acid in aqueous medium in good to high yields. Catalyst could be recycled for several time...
Article
Several new 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-ones were synthesized via the three-component condensation reaction of aldehydes, aromatic amines, and ethyl pyruvate under catalyst-free and solvent-free conditions. Also, 5-(4-hydroxyl-3-nitrophenyl)-1-(4-methoxy-phenyl)-3-(4-methoxyphenylamino)-1,5-dihydro-pyrrol-2-one was synthesized using ox...
Article
Full-text available
An efficient heterogeneous palladium catalyst system has been developed based on immobilization of Pd nanoparticles on silica-bonded N-propylpiperazine sodium N-propionate (SBPPSP) substrate. SBPPSP substrate can stabilize the Pd nanoparticles effectively so that it can improve their stability against aggregation. In addition, grafted piperazine sp...
Article
Silica-bonded N-propylpiperazine sodium n-propionate (SBPPSP) was found to act as an efficient solid base for the preparation of a series of 4H-benzo[b]pyran derivatives. SBPPSP was used as a recyclable heterogeneous solid base catalyst for the synthesis of 3,4-dihydropyrano[c]chromenes, 2-amino-4H-pyrans, 1,4-dihydropyrano[2,3-c]pyrazoles, and 2-a...
Article
A simple and efficient procedure for the preparation of 3-propyldiethylenetriaminesilica (PDTAS) by reaction of 3-chloropropylsilica with diethylene-triamine is described. 3-propyldiethylenetrianainesilica is employed as a recyclable base catalyst for the synthesis of 2-amino-4,6-diarylnicotininitrile from the reaction of acetophenone derivatives,...
Article
Silica-bonded N-propyltriethylenetetramine was prepared via the reaction between 3-silicapropyl chloride and triethylenetetramine. This heterogeneous solid base was used as a catalyst for the synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) by a one-pot condensation of aromatic aldehydes with 3-methyl-1-phenyl-5-pyrazolone in 72–93 % yields....
Article
Silica-bonded n-propyltriethylene-tetramine (SBNPTT) was found as an efficient solid base for the synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. Chromene derivatives were obtained via the three-component condensation reaction of aromatic aldehydes, malononitrile, and dimedone at 80 °C under solvent-free conditions. The heterogeneous so...
Article
A simple and sensitive spectrophotometric method to the simultaneous determination of Mn(2+) and Fe(3+) in foods, vegetable and water sample with the aid of artificial neural networks (ANNs) is described. It relies on the complexation of analytes with recently synthesised bis pyrazol base ligand as 4,4'[(4-cholorophenyl)methylene] bis(3-methyl-1-ph...
Article
An efficient heterogeneous Pd catalytic system has been developed, based on immobilization of Pd nanoparticles (PNPs) on a silica-bonded N-propylpiperazine (SBNPP) substrate. The SBNPP substrate effectively stabilizes the PNPs and improves their stability against aggregation. The catalytic activity of this catalyst was investigated in the cyanation...
Article
Silica-grafted N-propyl-imidazolium hydrogen sulfate ([Sipim]HSO4) is employed as a recyclable heterogeneous ionic liquid catalyst for the synthesis of 3,4-dihydropyrano[c]-chromenes by the reaction of aromatic aldehydes, malononitrile and 4-hydroxycoumarin at 100°C under solvent-free conditions. Also, heterogeneous ionic liquid catalyst was used f...
Article
The title acid catalyzes the four-component condensation of benzil (I), aliphatic and aromatic amines (II), aromatic aldehydes (III), and ammonium acetate under solvent-free conditions, possibly by increasing the electrophilicity of the carbonyl group of (I) and (III).
Article
Full-text available
A simple, sensitive and selective cloud point extraction procedure is described for the preconcentration and atomic absorption spectrometric determination of Zn2+ and Cd2+ ions in water and biological samples, after complexation with 3,3',3",3'"-tetraindolyl (terephthaloyl) dimethane (TTDM) in basic medium, using Triton X-114 as nonionic surfactant...
Article
An efficient enrichment procedure based on the combination of flame atomic absorption spectrometry (FAAS) and flotation for determination of Cd(2+), Ag(+) and Zn(2+) ions in various biological samples using new collector is studied. The influence of pH, amount of 2-(((1H-benzo[d]imidazol-2-yl)methoxy)methyl)-1H-benzo[d]imidazole (HBIMMHBI) as colle...
Article
A simple and efficient procedure for the preparation of silica-bonded N-propylpiperazine sodium n-propionate (SBPPSP) by the hydrolysis of silica-bonded N-propylpiperazine methyl n-propionate (SBPPMP) in hydrochloric acid (0.5 mol/L) followed by treatment with saturated sodium bicarbonate is described. The SBPPMP was obtained by the reaction of 3-s...
Article
α-Aminonitriles were synthesized via a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide using silica-bonded N-propylpiperazine sulfamic acid (SBPPSA) as a recyclable solid acid at room temperature. SBPPSA showed much the same efficiency when used in consecutive reaction runs.
Article
A highly selective synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles from the reaction of o-phenylenediamine and aromatic aldehydes in the presence of silica-bonded propyl-S-sulfonic acid (SBSSA) at 80°C in water in good to excellent yields was developed.
Article
A simple and efficient procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid (SBPTETSA) by the reaction of silica-bound N-propyl triethylenetetramine (SBPTET) with chlorosulfonic acid in chloroform is described. Silica-bound N-propyl triethylenetetramine sulfamic acid was employed as a recyclable catalyst for the...
Article
Silica-bonded N-propyl diethylenetriamine sulfamic acid (SBPDSA) is employed as a recyclable catalyst to synthesize a-aminonitriles. These syntheses involved one-pot condensation of an aldehyde, an amine, and trimethylsilyl cyanide under mild reaction conditions at room temperature. SBPDSA was recycled seven times in the condensation of benzaldehyd...
Article
Full-text available
Reaction of 18-crown-6 with KI in ethanol solution followed by addition of iodine (I2) afforded a unique triiodide salt with a nanotube-like structure ({[K.18-Crown-6]I3}n). It is shown that this reagent may be used for the chemoselective trimethylsilylation of alcohols. The synthesis of the crystalline reagent is a good example of crystal engineer...
Article
Full-text available
An efficient heterogeneous palladium catalyst system has been developed based on immobilization of Pd nanoparticles on silica-bonded N-propylpiperazine (SBNPP) substrate. SBNPP substrate can stabilize the Pd nanoparticles effectively so that it can improve their stability against aggregation. Also, grafted piperazine species onto the silica backbon...
Article
Full-text available
In this research at first palladium nanoparticle attached to a new chemically bonded silica gel has been synthesized and has been characterized with different techniques such as X-ray diffraction (XRD), fourier transform infrared (FT-IR), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Then, this new sorbent (chemica...
Article
Sulfuric acid ([3‐(3‐silicapropyl)sulfanyl]propyl]ester (SASPSPE) is used as a recyclable catalyst for the synthesis of 1,2,4,5‐tetrasubstituted imidazoles. A range of various polysubstituted imidazoles was synthesized via four‐component condensation of benzil, aldehydes, amines, and ammonium acetate in the presence of SASPSPE under solvent‐free co...
Article
The one-pot, multi-component synthesis of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) by tandem Knoevenagel-Michael reaction of phenylhydrazine, ethyl acetoacetate and aldehydes in the presence of silica-bonded N-propylpiperazine sulfamic acid (SBPPSA) as a recyclable solid acid catalyst was reported. SBPPSA showed much the same efficiency when used...
Article
A simple and efficient procedure for the preparation of silica-bonded propylpiperazine-N-sulfamic acid (SBPPSA) by the reaction of 3-piperazine-N-propylsilica (3-PNPS) and chlorosulfonic acid in chloroform is described. Silica-bonded propylpiperazine-N-sulfamic acid is employed as a recyclable catalyst for the synthesis of highly substituted imidaz...
Article
Full-text available
A very simple cloud point extraction (CPE) methodology for the preconcentration of trace amounts of silver and magnesium as a prior step for their determination by flame atomic absorption spectrometry (FAAS) has been developed. The method is based on the extraction of silver and magnesium at pH 10 by using non-ionic surfactant Triton X-114 and 4 me...
Article
Full-text available
Preparation of N-(3-silicapropyl) imidazolium hydrogen sulfate ([Sipim]HSO4) as a heterogeneous acidic ionic liquid is described. This heterogeneous ionic liquid was used as catalyst for the synthesis of α-aminonitriles by a one-pot condensation of aldehydes, amines, and trimethylsilyl cyanide at room temperature. Catalyst could be recycled for sev...
Article
Full-text available
A stable organic tribromide, [H2-cryptand 222]2+(Br3–)2 was utilized as an active catalyst for the trimethylsilylation/ tetrahydropyranylation of alcohols. The method is general for the preparation of OH-protected aliphatic (acyclic and cyclic), aromatic, primary, secondary and tertiary alcohols.
Article
Sulfuric acid ([3-(3-silicapropyl)sulfanyl]propyl)ester is employed as a recyclable catalyst for the condensation reaction between aromatic aldehydes and 3-methyl-l-phenyl-5-pyrazolone. This condensation reaction was performed in ethanol under refluxing conditions giving 4,4′-alkylmethylene-bis(3-methyl-5-pyrazolones) in 74-90% yields. The heteroge...
Article
A highly selective synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles from the reaction of o-phenylene-diamine and aromatic aldehydes in the presence of sulfuric acid {[3-(3-silicapropyl)sulfanyl]propyl}ester (SASPSPE) in water and at 80°C in good to excellent yields.
Article
Full-text available
2,3-Dihydroquinazolin-4(1H)-one derivatives were synthesized via a one-pot, three component reaction of isatoic anhydride and an aromatic aldehyde with ammonium acetate or primary amine catalyzed by silica-bonded S-sulfonic acid in ethanol at 80°C. The reaction work-up is simple and the catalyst is easily separated from the products by filtration....
Article
2,3-Dihydroquinazolin-4(1H)-one derivatives are synthesized via a one-pot, three component reaction of isatoic anhydride and an aromatic aldehyde with ammonium acetate or primary amine catalyzed by silica-bonded N-propylsulfamic acid (SBNPSA) in refluxing ethanol.
Article
Full-text available
Iodine and iodine supported on polyvinylpyrrolidone (betadine) have been used as catalysts for ring opening of epoxides and as reagent for ring-opening dimerization of thiiranes in alcohols, water, and acetic acid. The reactions occur with high regio-, chemo-, and stereoselectivity. The reaction of R-(+)-styrene oxide with I2 supported on PVP in me...
Article
Full-text available
Reaction of 18-crown-6 with KI in ethanol solution followed by addition of iodine (I
Article
A method of separation and preconcentration for the determination of Zn, Cu, and Mn in natural water was described and real samples studied using flame atomic absorption spectrometry. The method is based on the adsorption of Mn2+, Cu2+ and Zn2+onto 3-((1H-Indol-3-yl)(3-nitrophenol)methyl)-1H indole (INMI) that is loaded onto Triton X-100-coated pol...
Article
Full-text available
Bis((1H-benzo[d]imidazol-2yl)methyl)sulfane (BHIS) was used as a complexing agent in cloud point extraction for the first time and applied for selective pre-concentration of trace amounts of silver. The method is based on the extraction of silver at pH 8.0 by using non-ionic surfactant T-X114 and bis((1H-benzo[d]imidazol-2yl)methyl)sulfane as a che...
Article
The proposed research describes the application of cloud point extraction (CPE) methodology for the preconcentration of ultra-trace amounts of Cu 2+, Co 2+, Zn 2+, and Mn 2+ ions prior to their determination. In this technique, non-ionic surfactant Triton X-114 in the presence of (2-(pyridin-2-yl)-1H-benzo[d]imidazole) (PBI) as chelating agent has...
Article
A number of macrocyclic diamides have been synthesized from the reaction of a diacid dicarboxylic dichloride with primary diamino compound in the presence of magnesium oxide‐silica gel at room temperature in good yields. Using urea and thiourea as well as diamines to produce the corresponding macrocycles in the range of 52–56% yields are also inclu...
Article
Silica-supported tin chloride and titanium tetrachloride were prepared by the reaction of tin chloride and titanium tetrachloride with activated silica gel in refluxing toluene. These solid acids have been employed as the catalysts for the synthesis of bis-dihydropyrimidin-2(1H)-ones from aromatic dialdehydes, 1,3-dicarbonyl compounds and urea at 9...