Khamsah Mohd

Sultan Zainal Abidin University | unisza · Faculty of Bioresources and Food Industry

Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti-inflammatory, antioxidant, antibacterial, antifungal, anti-hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malay...

Recently, stingless bee propolis has gained attention in the food market, mainly due to its pharmacological properties. Previous studies have reported the higher antioxidant properties of Geniotrigona thoracica propolis extract. In this paper, we report on the bioassay-guided fractionation of the active n-hexane fraction of G. thoracica propolis an...

Background: The herb Melastoma malabathricum is used widely in Malaysia and other Asian countries for its health benefits and quality control of the herb is vital as there are closely resembling species. This study used morphologically authenticated samples to study the feasibility of ATR-FTIR spectroscopy in combination with chemometrics to differ...

The growing demand for agricultural products for food requirements caused the use of excessive inorganic chemical fertilisers, insecticides, fungicides, and pesticides for a quick and simple way to maximise and boost crop yield. This practice harmed food safety and caused the degradation of environmental, physical, and biological conditions. It has...

Phytochemical investigation through cytotoxicity bioassay-guided isolation of Geniotrigona thoracica propolis led to the identification of five cycloartane-type triterpenes, including mangiferonic acid 1, ambonic acid 2, mangiferolic acid 3, ambolic acid 4 and cycloartenol 5. Their structures were established based on detailed spectroscopic analysi...

Maize breeding appears to be a key strategy to ensure global food security. Improving the grain yield and nutritional quality of maize can progress through breeding programs, where hybridization between two genetically contrasting inbreds might lead to producing superior hybrids. This phenomenon occurs as the developed hybrids are 100% heterozygous...

Piper sarmentosum was found to have various phytochemicals such as polyphenols and flavonoids but also contains asarone isomers, which were reported as carcinogenic in several preclinical studies. Therefore, reducing asarone isomers from this functional food is important while retaining its functional properties. This study compares the total pheno...

Stingless bees or locally known as Kelulut is a special of bees that already been part of people livelihood around the world since ancient time. Even through they are not as honey bees, their contribution as pollinators to thousands of plant species are not trivial. In comparison to other group of bees, stingless bees are more diverse and versatile...

Malaysia is blessed with various medicinal plants that can potentially treat multiple diseases. One of the most studied plants is the misai kucing plant. Orthosiphon stamineus Benth (Misai Kucing) is a herbal plant from Southeast Asia, including Malaysia. Several studies have been conducted, and many findings have been discovered about the efficacy...

Geniotrigona thoracica is a stingless bee species of Trigona genus. Propolis resinous is a natural product obtained from a honeybees hive with geographical and floral specifications or exudate as such by-products resulting from a variety of botanical processes. Despite its long use for a variety of health conditions, the toxicity profile of propoli...

The present study was carried out to evaluate the effects of different rates of macronutrients as a foliar spray on the growth performance, yield, and nutrient content of sweet corn grown in the Rengam soil series. The treatments consisted of five rates of macronutrients as a foliar fertilizer at 0, 25, 50, 75, and 100 % NPK. Foliar NPK was applied...

Cadmium (Cd) is one of the highly toxic, non-essential heavy metals that inhibit plant growth and development by prompting chlorophyll loss and affecting photosynthetic activities. This study investigated the efficacy of Spirulina platensis and Sargassum polycystum extracts in alleviating Cd stress in Pak Choi at morpho-biochemical, anatomical, and...

Propolis is a natural substance produced by the bees to protect their hive. The present work reports the utilization of chemical profiling and fingerprinting combined with multivariate analysis for discrimination of the geographical origin of Malaysian stingless bee propolis. High Performance Thin Layer Chromatography (HPTLC) has been performed to...

Cucumber (Cucumis sativus L.) is an important vegetable crop in the world and the third largest vegetable crop in Malaysia in terms of planting area. Available hybrids in the market reached a yield plateau due to insufficient exploitation of hybrid vigour and susceptibility to Begomoviruses. The present study aimed to evaluate 20 cucumber F1 hybrid...

Propolis is a natural remedy used in folk medicine and believed to have a broad spectrum of biologically active with therapeutic properties. Propolis consists of several different materials collected by the bees including resin, wax, latex etc and used to protect their hive from predator and microorganism. In order to harness its therapeutic benefi...

Growth improvement of the medicinal plant, Ficus deltoidea (Mas Cotek) under drought conditions is a vital issue in Malaysia since it is a slow-growing plant and disposed to leaf damage under the stresses of drought. Therefore, investigation was done to examine the outcomes of hydrogen peroxide (H2O2) application on Rubisco gene expression and meta...

Lemon trees (Citrus lemon L.) are among the trees scattered in Southeast Asia, especially Malaysia, The importance of lemons has increased in recent times, especially after the spread of the Covid-19 epidemic around the world, as lemon juice rich in vitamin C is fortified for the immunity of the human body. Also, it is an important source of Flavon...

The wax apple or jambu madu, is a non-climacteric tropical fruit from Myrtaceae family and widely cultivated in South East Asia. The limited availability of good quality seedlings of wax apple is the main problem to development of flourish it's market share in the current fruit industry. Therefore, in order to produce good quality planting material...

Highlights Poultry dung enhances the vegetative growth and plant physiology of pumpkins. AGR, RGR, LAI, LAR, LAD, and biomass of pumpkin affect positively by poultry dung. Poultry dung stimulates the flowering, fruit formation, and quality of pumpkin. Abstract A field study was carried out to examine the effects of organic amendment on the morpho-p...

Cadmium (Cd) is one of non-essential heavy metals which is released into environment naturally or anthropogenically. It is highly persistent toxic metals that are exceptionally distressing industrial and agriculture activities by contaminating soil, water and food. Its long-duration endurance in soil and water results in accumulation and uptake...

The wax apple or jambu madu, is a non-climacteric tropical fruit from Myrtaceae family and widely cultivated in South East Asia. The limited availability of good quality seedlings of wax apple is the main problem to development of flourish it’s market share in the current fruit industry. Therefore, in order to produce good quality planting material...

Due to their role in cell growth and survival, HDAC (II), JAK 2 and EGFR receptors are important targets in many chemotherapies that aim to produce their biological response in malignancy solid tumors. In this work, several 4-hydroxybenzamide analogues coupled with 1,3-benzodioxole, a,ß-unsaturated carbonyl, and tert-butyl ester bases small molecul...

Seaweeds are plants found in sea that have tremendous applications in the fields of agriculture and environment. It comprises of three giant classes with a large number of different species. their ability to adopt to various conditions qualifies them more applicable to various environmental and agricultural arena. Agriculturally, both three classes...

Sejak penularan wabak pandemik COVID-19, dunia menyaksikan peralihan norma baharu yang sangat drastik, termasuklah dalam aspek pendidikan. Penularan COVID-19 pada akhir bulan Januari di Malaysia telah meletakkan aktiviti pendidikan di semua peringkat berada dalam keadaan luar daripada kebiasaan. Seluruh jentera di bawah Kementerian Pendidikan Malay...

Hydrogen peroxide (H2O2) is a broad-range chemical catalyst that is receiving rapidly increasing attention recently due to its role as a signaling molecule in various plant physiological and biochemical processes. A study was carried out to investigate the effects of H2O2 on the plant physiology, root growth, mineral nutrient accumulation, root ana...

With the increasing demand for safe and clean fruits free of substances harmful to human health, bio-fertilizers are conceder one of the active factors in this direction. Microorganisms, whether fungi (Arbuscular mycorrhiza) or bacteria (Plant Growth Promoting Bacteria) provided enhancing growth, development, and fruit quality. Trichoderma harzianu...

This study was conducted to evaluate the potential effects of branch bending angle on the plant physiological characteristics, mineral nutrients accumulation and fruit quality of wax apple. Different treatments with five replicates each by Randomized Complete Block Design (RCBD) layouts were arranged in this study. All the treatments represent diff...

Waste from the food is a challenge to the environment all over the globe, hence there is need to be recycled. Vegetables and fruits biomass is a resource of renewable energy with significant fuel source potential for the production of electricity and steam, fuel for consumption and laboratory solvents. Bioethanol derived from biomass contributed 10...

The present study was carried out to investigate the effects of hydrogen peroxide (H 2 O 2) on the growth, photosynthesis, leaf histology, mineral uptake, phytochemical accumulation, and Rubisco gene expression in Ficus deltoidea var. deltoidea, a slow growing medicinal plant. The F. deltoidea plants were spray-treated with 0 (control), 8, 16, 30 a...

This study was carried out to investigate the regulatory effects of hydrogen peroxide (H2O2) on the growth, photosynthesis, biochemical properties, leaf anatomy and Rubisco gene expression in Ficus deltoidea var. deltoidea, a slow-growing medicinal herb. Results showed that 20-mM H2O2 treatment increased plant height, net photosynthetic rate, stoma...

Background: Uterine fibroids are a common type of solid tumor presenting in women of reproductive age. There are very few alternative treatment available from conventional treatment involving surgeries. Labisia pumila var. alata or locally known as 'Kacip Fatimah' was widely used as traditional medicine in Malaysia. This plant has been used to mai...

Heterotrigona itama is one of common stingless bee species in Malaysia. Similar to sting bee, stingless bee also produce honey, propolis and beebread in their hive. Propolis and beebread of Malaysian stingless bee were less explored compared to honey. This work examine nutritional content, antioxidant activity and chemical profiling of honey, propo...

Hydrogen peroxide (H2O2) is defined as a reactive oxygen species (ROS), able to cause damage to a variety of cellular structures. On the other hand, recent work has demonstrated that H2O2 can also act as a potent signalling molecule that mediates various physiological and biochemical processes in plants. This study was carried out to investigate th...

Propolis is a sticky material manufactured by stingless bees to build and protect their hive. This material is known to be a rich source of biologically active constituents. Chemical composition that is attribute to its biological activities is highly dependent on plant sources and geographical origin. Chemical profiling was performed on Malaysian...

Importin-α serves as an adaptor linking importin-β to proteins carrying a nuclear localization sequence (NLS). During interphase, this interaction enables nuclear protein import, while in mitosis it regulates spindle assembly factors (SAFs) and controls microtubule nucleation, stabilization and spindle function. Here, we show that human importin-α1...

This study was designed to assess the effects of different types of organic matter on the quality and biochemical properties of red seedless watermelon. The research was a single factor experiment, which involved six (6) treatments and four (4) replications. Watermelon grown and harvested from five (5) different organic matter sources, namely; verm...

Propolis is a plant-derived substance collected by stingless bee's product from various sources, including plant resins with combination of bee's saliva and wax. Propolis has been used to treat several diseases since ancient times and it is an important source of bioactive natural compound and drug derivatives. The aim of this study was to evaluate...

Propolis is a mixture of resin collected by the bees to build their hive. These mixtures contain natural remedy and used to treat variety of health-related problems. Unlike honeybee propolis, the study of stingless bee propolis still lacking. The important part of propolis study is the optimization of extraction procedures. The aim for this study i...

Propolis is a sticky substance made up of mixture of plant resin, wax and bee saliva. Propolis has been used in various health related problems as well as cosmetic ingredient. This work was evaluating chemical fingerprint of Malaysian stingless bee propolis produced by two species, Heterotrigona itama (HI) and Geniotrigona thoracica (GT). Chemical...

Propolis has been used as therapeutic agent since ancient time and considered as high value materials. In order to obtain maximum yiel d of extract production with excellent biological activity, extraction techniques need to be established. This study aimed to optimize extraction protocol and screen total phenolic, total flavonoid and antioxidant a...

Propolis is a sticky material manufactured by bees to build and protect their hive. Propolis had been used worldwide for years in folk medicine. The aim of this paper is to give information about traditional uses, phytochemical screening and pharmacological studies of propolis in the world by using secondary references such as journals and articles...

The study was conducted to identify the best eating quality of some common fruits in the Malaysian local market. The selected market fruits such as papaya, mango, banana, wax apple (jambu madu) and tomato were collected from local markets located in Besut, Terengganu, Malaysia at different ripening stages. The qualities of these fruits were determi...

A study was conducted at the teaching and research farm of the Faculty of Bioresources and Food Industry at Universiti Sultan Zainal Abidin (UniSZA) with an objective of determining the best rates for vermicompost application on red seedless watermelon var. Crimson sweet. In this research, watermelon crimson red flesh seedless variety was used as p...

Objectives The effects of water and 50% ethanolic-water extracts of Orthosiphon stamineus Benth (OS) on cell proliferation and apoptotic activity against uterine leiomyosarcoma (SK-UT-1) cells were investigated. Methods Anti-proliferation effect was evaluated through cell cycle analysis whereas apoptotic activity was determined via screening and q...

Pattern based approach has been used for quality control for identification and authentication of herbal medicines including plant that having varietal issue, Ficus deltoidea Jack (FD). Chemical fingerprinting of FD varieties were profiled by Gas Chromatography-Mass Spectrometry (GC-MS). The aim was to profile and classify the untargeted volatile c...

Propolis is a sticky material manufactured by bees to build and protect their hive. Propolis had been used worldwide for years in folk medicine. The aim of this paper is to give information about traditional uses, phytochemical screening and pharmacological studies of propolis in the world by using secondary references such as journals and articles...

Propolis is a gum-like product that collected by bees from plants and it varies in colour range from light yellow to dark brown. The chemical composition of propolis depends on various factors such as vegetation, season and environmental conditions of the sample collection. The aim of the study was to determine the chemical profile and antioxidant...

Soil-based cultivation is presently confronting dire challenges to the lack of land availability, massive escalation rate of industrialization and intense urbanization. Land-related agriculture is at stake due to irrepressible climate vicissitudes, relentless soil degradation, unbefitting management practices and other adversative effects. The sett...

This study evaluates the primary and secondary metabolite profiles of Jack (EL) stems and leaves to the roots. A total of six types of extracts were tested. The extracts showed high content of glycosaponins, polysaccharides, proteins and phenolics. The presence of flavonoids and phospholipids was also detected. High Performance Thin Layer Chromatog...

This paper investigates the effect of processing and antioxidant activity of Malaysian Chromatography (HPTLC) analysis compounds were degraded or affected by extraction method extraction methods significantly affect chemical profiles. antioxidant activity were in agreement with possesses significantly higher This finding shows that metabolite profi...

This study aim to evaluate gravimetric parameters and physicochemical of raw materials of Orthosiphon stamineus in order to ascertain the quality of plant materials and achieved standardized material. Anti-uterine fibroid potential was investigated by cytotoxicity test on uterine leiomyosarcoma cell SK-UT-1. Gravimetric analysis showed that all par...

Ficus deltoidea Jack (FD) is a highly potential herb. However, there is serious confusion on selecting the right plant as FD occurs in several varieties. In this study, a high-performance thin layer chromatography (HPTLC) method was developed to determine the discriminating factors of FD varieties. Eight varieties of methanol extract, five varietie...

Ficus deltoidea Jack (FD) is a plant belonging to the Moraceae family and found in tropical and subtropical countries. Reports indicate that 13 varieties of this plant can be found in Malaysian forest. Scientific evidences revealed that FD possesses several biological activities such as antioxidant, anti-inflammatory and antidiabetic. The issue on...

The aim of this study is to evaluate chemical and biological profile of methanol extracts from Malaysian propolis produced by two commonly found stingless bee species, Heterotrigona itama (MHI) and Geniotrigona thoracica (MGT). Test samples were analyzed for physicochemical parameters such as moisture, fat, crude fibre, crude protein, carbohydrate...