Khalid Olajide Adekoya

University of Lagos | Unilag · Department of Cell Biology and Genetics

Background Colour vision deficiency (CVD), also referred to as colour blindness, is the failure or decreased ability to distinguish between certain colours under normal lighting conditions. It is an X-linked genetic disorder with varying degrees of prevalence in different populations. There is presently no report on the prevalence of CVD among stud...

Background : Wenyonia Woodland, 1923 represents a monophyletic lineage of Caryophyllidean tapeworms that exclusively infect mochokid catfishes of the genus Synodontis . In Nigeria, information on the molecular characterization of Wenyonia sp tracing the phylogenetic relationship within the genus is lacking. This study was therefore aimed to evaluat...

Background Recent studies have shown parasites as accumulation indicators that give critical information about the bioavailability of pollutants. To further buttress parasites in the assessment of metal sink potentials, the parasite Cosmocerca sp. was analyzed in a total of 168 host toads, Sclerophrys regularis , from three (3) study stations sampl...

A subgroup among people living with HIV (PLHIV) experience viral suppression, sometimes to an undetectable level in the blood and/or are able to maintain a healthy CD4+ T-cell count without the influence of antiretroviral (ARV) therapy. One out of three hundred PLHIV fall into this category, and a large sample of this group can be found in areas wi...

This study was carried out to evaluate the effect of effluent and influent, from a beverage plant in Lagos state, using haematology, sperm assay, and impact of the physicochemical parameters on mice. The effluent and influent were collected in sterile bottles and were separately administered orally to 5 groups of mice at test concentrations of 6.5%...

Background Amphibian species are being threatened worldwide and chemical pollution is one of the leading causes of this decline. The use of agrochemicals such as organochlorine pesticides (OCPs) among the several health and ecological challenges it causes, the sharp amphibian population decline is most pressing. Toad specimens Amietophrynus regular...

Parasitic infection of fish is seen worldwide, and they are of particular interest in the tropics. Reports indicate that parasite infections in fishes lead to a disruption in aquaculture production. This study was undertaken to determine the association between physicochemical parameters and the abundance of Wenyonia sp Woodland, 1923 in Synodontis...

Background The human external ear is unique in every individual in terms of shape, size and dimension making it suitable in forensic anthropology for sex estimation and personal identification purposes. The study aimed to evaluate sexual dimorphism and ethnic specificity of the external ear in major Nigerian ethnic populations. Results There was v...

Immunogenomics studies have been largely limited to individuals of European ancestry, restricting the ability to identify variation in human adaptive immune responses across populations. Inclusion of a greater diversity of individuals in immunogenomics studies will substantially enhance our understanding of human immunology.

The degree of genetic variation in a population clearly specifies the structure of stocks and the probability of sustenance in future. The portunid crab, Callinectes amnicola, is presently managed as a single stock in Nigeria. Hence, genetic heterogeneity in this species from three interconnecting lagoons (Badagry, Lagos and Epe) was analysed using...

Abstract Background: COVID-19 pandemic caused by SARS-CoV-2 remains a global health threat. Assessment of the genetic relatedness of the genome sequence is a prerequisite to understanding the dynamics, which is important to improve diagnosis and preventive measures. This study determined genomic diversity and SNP characteristic of genomes of SARS-C...

Background: Amphibians are subjected to a variety of natural and artificial stresses that can compromise physiological balance. This study explored the variations in oxidative stress markers in Cosmocercan parasitized and non-parasitized Amietophrynus regularis in diverse conditions. The toad specimens were collected from natural habitats and dumps...

Variations in the CD4 and vimentin (cluster of differentiation 4) genes among Nigerian indigenous and commercial poultry species were investigated to reveal the evolutionary relationship among the poultry group. Genes amplifications were done from isolated DNA using polymerase chain reaction method (PCR) and sequenced. Amplicons of 125bp and 410bp...

Background A disturbance in eating behaviour (EB) is the hallmark of patients with eating disorders, and depicts a complex interaction of environmental, psychological and biological factors. In the present study, we propose a model of association of genetic susceptibility—represented by adiponectin ( ADIPOQ ) gene—with eating behavioural and psycho...

Morphogenetic traits are observable characters inherited by individuals from their parents in autosomal dominant or recessive manner and expressed differently among populations. The differences in inheritance and expression of these traits usually form the basis of diversity and variation among populations. This study was carried out to ascertain t...

The use of psychoactive substances for several reasons by commercial vehicle drivers has been documented as a major cause of increased incidences of traffic accidents globally. The study aimed at determining the prevalence of psychoactive substance use among Nigerian male commercial vehicle drivers randomly selected from the three major ethnic grou...

Electronic industry is one of the most prominent and advanced in the world, producing significant complex waste known as electronic-waste (e-waste). One of the challenges of e-wastes is the concern raised about the toxic effect of their components. This study investigates the effect of e-waste from Alaba International market in Lagos, Nigeria on Dr...

Length of toes and patterns of prints in humans have been variously associated with ancestry, astrology, Intelligence Quotient, personality and other genetic parameters. This link has not been sufficiently studied in Nigerian population. Morphology provides basis towards understanding genetics. The study is aimed at assessing the incidence of the d...

Length of toes and patterns of prints in humans have been variously associated with ancestry, astrology, Intelligence Quotient, personality and other genetic parameters. This link has not been sufficiently studied in Nigerian population. Morphology provides basis towards understanding genetics. The study is aimed at assessing the incidence of the d...

Aim: This study investigated relatedness among three indigenous chicken types using morphological features and morphological trait interdependence within three indigenous poultry species in Nigeria. Study Design: A complete Random sample design was employed in this study to investigate morphological relatedness. Place and Duration of the Study: Bir...

The degree of genetic variation in a population clearly specifies the structure of stocks and the probability of sustenance in future. Genetic diversity in the Lagoon Crab, Callinectes amnicola populations from three interconnecting lagoons (Badagry, Lagos and Epe) was analysed using randomly amplified polymorphic DNA technique. The DNA yield and p...

Background Adiponectin plays key roles in regulating appetite and food intake. Altered circulating adiponectin levels have been observed in human eating disorders such as anorexia nervosa, bulimia nervosa or binge eating. In addition, an association between circulating adiponectin levels and human eating behaviour (EB) has been reported. Interestin...

The population distribution of fingerprint minutiae is necessary to improve efficiency of fingerprints in identifying individuals in a population-specific manner. The objective of the study was to determine the distribution of different types of minutiae fingerprint feature in two Nigerian ethnic populations. Fingerprints from forty-four (44) Igbo...

The natural resistance-associated macrophage protein 1 (NRAMP1) gene in chickens, which exists on chromosome 7, is thought to play a significant role in disease resistance. Variations in this gene have been documented and have played crucial roles in the variations in the resistance and/or susceptibility that is expressed by individuals and differe...

Y-chromosome short tandem repeats (Y-STRs) are specialized class of short tandem repeats located on human Y (male) chromosomes and are passed unchanged (barring a mutation) from one generation to the next. They are widely used in population genetic studies, forensics, paternity and genealogical DNA testing. The non-recombining nature of these loci...

The Acrididae exhibits a stable karyotypic uniformity or conservatism and are typical specimen for cytological and meiotic investigations. Despite the diversity and cytotaxonomic value of this family, however, there are only few studies on their karyology. This paper is therefore aimed at describing the karyotype and meiotic behaviors of chromosome...

Pharmaceutical effluents contain toxic xenobiotics capable of contaminating aquatic environments. Untreated effluents are illegally discharged into aquatic environment in most developing countries. Pharmaceutical effluent induced alterations in biomarkers of genetic and systemic damage on rodents. However, information is relatively scarce on the po...

Solanum L., is the largest genus of the family Solanaceae with over 2,000 species. Considering their worldwide distribution, a remarkably high level of morphological diversity has manifested at the species, the cultivar and the generic levels. This coupled with the crossability affinities between S. melongena and other distantly related Solanum spe...

Entomology Journal publishes original research papers and reviews from any entomological discipline or from directly allied fields in ecology, behavioral biology,

Garcinia kola is an important indigenous fruit tree that has a huge medicinal and economic value in Nigeria. It is often referred to as 'wonder plant' because all its parts have specific medicinal properties and have been employed traditionally for the treatment of diverse ailments. This study is aimed to determine the genetic variation that exists...

The objective of this study was to assess the leaf epidermal micro-morphology in some Vernonia species in Nigeria. .In–situ morphological characterization was carried out on 61 field samples consisting of 14 Vernonia species collected from Nigeria. Light microscopic studies of the foliar epidermal micromorphology were undertaken on the 14 Vernonia...

The three major ethnic groups of Nigeria namely the Hausa, Igbo and Yoruba make up 29, 21 and 18% of the total population, respectively. To provide genetic information necessary for forensic analysis, this study was carried out to determine STR allele frequencies in 102 Hausa, 128 Igbo and 134 Yoruba individuals in Nigeria using 21 STR loci includi...

In the original paper author Alani Sulaimon Akanmu was erroneously omitted from the author list. Prof. Akanmu has now been added as 4th author. Prof. Akanmu acted as an academic supervisor of the study and additionally contributed to the publication by reading, commenting and editing the manuscript.

Vernonia Schreb. is a genus in the family Asteraceae. It has over 1000 species which may be trees, shrubs, woody climbers or herbs. Some of the species are economically important as sources of food and herbal medicine as well as for industrial purposes. This study was carried out to assess the genetic diversity of Vernonia species in Nigeria. Molec...

Global demand for seafood products alone is projected to increase by 70 percent in the next 30 years as harvests from traditional capture fisheries either remain stable or continue to decline. At the same time, coastal marine ecosystems worldwide that support wild shellfisheries are threatened by pollution, habitat degradation, overharvesting and a...

The robustness of short tandem repeats for use in forensic and paternity depends on their high polymorphism and mutation rate. This study tried to determine the event of mutation of two miniSTR loci in the Yoruba population. Blood samples were collected from five father-motherchild trios of Yoruba origin. Two DNA extraction methods, an homemade met...

Humans in modern society are exposed to an ever-increasing number of electromagnetic fields (EMFs) and some studies have demonstrated that these waves can alter brain function but the mechanism still remains unclear. Hence, this study sought to investigate the effect of 2.5 Ghz band radio-frequency electromagnetic waves (RF-EMF) exposure on cerebra...

The advent of Wi-Fi connected high technology devices in executing day-to-day activities is fast evolving especially in developing countries of the world and hence the need to assess its safety among others. The present study was conducted to investigate the injurious effect of radiofrequency emissions from installed Wi-Fi devices in brains of youn...

Setcreasea purpurea Boom (Wandering Jews) belongs to the family Commelinaceae of order commelinales. The family made of 38 genera and about 600 species occur mostly in the tropical and warm regions of the world. Many are popular as garden or house ornamentals. It is a flower-bearing plant yet it is mostly propagated vegetatively due to formation of...

Background: The association of obesity with adiponectin gene has been reported in different populations with various inconsistencies. Data from Nigeria is very scanty on the association. Aim: We investigated possible associations of adiponectin gene (ADIPOQ) single nucleotide polymorphisms (SNPs) rs2241766 (+45T>G in exon 2), rs266729 (-11377C>G in...

The forensic identification of closely related individuals genetically has often been difficult probably due to strong phenotypic concordances. Short tandem repeats (STRs) have been used in kinship tracing, identifying missing person and skeletal remains, paternity testing and mass disasters victim identification. This research was performed to det...

Fruit drinks are a perfect fast food for today's eat on the run lifestyle. In this study, Drosophila melanogaster flies were exposed to three local and common orange flavoured drinks (Nutri-C, Sari-C and Eve). The Drosophila melanogaster flies were fed on a Banana-Garri medium containing the test substances in varying concentrations (1, 2, 5, 10, 2...

Short tandem repeats (STRs) are presently the most widely used genetic markers in forensic DNA investigations, paternity testing and human identification testing. These genetic markers forming a DNA profile are found at different frequencies in the population. Aim: To determine STR allele frequencies for the Hausa, Yoruba and Ibo population in 15 S...

Objective: The study aim was to determine the hemoglobin genotypic and allelic distributions in fetal population, and to quantitatively evaluate the effect of heterozygous maternal DNA contamination of homozygous fetal DNA in chorionic villi, on fetal hemoglobin genotypes. Materials and Methods: A descriptive, cross sectional study of amplification...

Obesity and food intake have been shown to impact academic performance in younger students, but data for university students are sparse. The purpose of this study was to investigate effect of obesity, as measured by body mass index (BMI) and food intake on academic performance of university students. Four hundred biology undergraduates in a Nigeria...

ABSTRACT Setcreasea purpurea Boom (Wandering Jews) belongs to the family Commelinaceae of order commelinales. The family made of 38 genera and about 600 species occur mostly in the tropical and warm regions of the world. Many are popular as garden or house ornamentals. It is a flower-bearing plant yet it is mostly propagated vegetatively due to for...

Solanum L., the largest genus of the family Solanaceae with over 2,000 species includes perennial shrubs, herbs, or trees, with or without spines, glabrous or pubescent with unbranched or branched, often glandular hairs. Considering their worldwide distribution, a remarkably high level of morphological diversity has manifested at the species, the c...

Background: There is unprecedented increase in the processing and packaging of many plant materials into food supplements, herbal medicine, skincare and cosmetic products for human needs. Baphia nitida is used for topical skincare products. Toluene, a toxic aromatic solvent, is increasingly being used in the production of these skincare and cosmeti...

The common name “Eggplant” is given to vegetables of several Solanum L. species that are important for human diet and health. The taxonomy and phylogenetic relationships among these taxa are currently unclear due to its large size and tropical center of diversity. This study assessed the genetic diversity in forty nine eggplant and related Solanum...

The taxonomy of Solanum melongena L. also known as brinjal eggplant has remained difficult because previous studies to establish genetic relationships among taxa are mainly based on morphological features, which are insufficient to establish genetic affinities. In the present investigation, five highly polymorphic random amplified polymorphic DNA p...

Solanum L., the largest genus of the Solanaceae family, vary morphologically, is diverse in number and is ecogeographically distributed. In Nigeria, previous studies had focused mainly on chromosome morphology, genome description and medicinal values, which are insufficient for genetic affinities. This study used four highly polymorphic random ampl...

The Prevalence of lethal yellowing disease (LYD), insect vectors and premature nut fall of the coconut palms have been studied within the locations and states visited in Nigeria. The locations were fields with mixture of dwarfs, hybrids and West African tall coconut palms including decapitated coconut stems. The prevalence of LYD was higher in the...

The relationship between dermatoglyphics and multiple intelligences (MIs) were investigated in this study. 210 subjects from seven secondary schools in Lagos State, Nigeria were examined on heritable MIs; linguistic, logic/Math, intrapersonal, interpersonal, kinesthetic, musical and natural intelligences. The ten fingerprint patterns were captured...

The relationship between dermatoglyphics and multiple intelligences (MIs) were investigated in this study. 210 subjects from seven secondary schools in Lagos State, Nigeria were examined on heritable MIs; linguistic, logic/Math, intrapersonal, interpersonal, kinesthetic, musical and natural intelligences. The ten fingerprint patterns were captured...

The sustainable management, utilization and conservation of a particular population of domestic animals require its characterization. Standard characterization and evaluation of particular populations of domestic animals may be carried out by using different methods, including traditional practices such as the use of descriptor lists of morphologic...

In this study, a cowpea breeding programme was set up to develop varieties with long pods that may combine early maturing and pest resistance. The strategies were to combine the early maturing characters of cultivated cowpea (Vigna unguiculata ssp. unguiculata cv-gr unguiculata) with long pod characters of yard long bean (V.unguiculata ssp. unguicu...

The ameliorative impact of salicylic acid (SA) and ethylene diamine tetraacetic acid (EDTA) on cytogenetic and growth changes induced in Allium cepa by toxic concentration of copper (Cu) was investigated. Onion bulbs were treated with solutions prepared from different combinations of these substances: Cu (100.79 mmol l-1), Cu + EDTA (1273.75 mmol l...

Pigmentation plays important adaptation and physio- logical efficiency roles in animals. In the sequence of a 648 bp fragment representing intron 1, exon 2, and part of intron 2 of the MLPH mammalian pigmenta- tion gene, we identified a novel g.469C > G mutation in intron 2, and genotyped it in 266 Nigerian goats using PCR-RFLP analysis. The C alle...

Populations of Nigerian Drosophila are hardly distinguishable in morphology but reproductively isolated. Spectrophotometric analysis of genomic DNA of the fruitflies reveals that the DNA extraction protocol used yielded genomic DNA good enough for polymerase chain reaction, confirming claims that polymerase chain reaction is possible even when amou...

The agouti-signaling protein (ASIP) plays a major role in mammalian pigmentation as an antagonist to melanocortin-1 receptor gene to stimulate pheomelanin synthesis, a major pigment conferring mammalian coat color. We sequenced a 352 bp fragment of ASIP gene spanning part of exon 2 and part of intron 2 in 215 animals representing six goat breeds fr...

Three adult local chicken types in Nigeria (wild type. Ibile; naked neck, Abolorun, and frizzled feather; Asaa; and three exotic types; Bovans near, Isa Brown and Cobb) were characterized using twenty morphological traits. The descriptive analysis: group means and the standard deviation values of the 20 traits studied showed significant differences...

The genus, Amaranthus, is a typical annual flowering plant valued as vegetables, grains and ornamentals. It exhibits a high degree of interspecies variability and as such enhances biodiversity. Two common grain types (A. caudatus and A. cruentus) and three major weedy types (A. hybridus, A. spinosus and A. viridis) were studied. Phenotypic traits w...

Allium cepa assay has been used extensively to determine the cytotoxicity and genotoxicity of compounds on plants and animals. The cytogenetic effects of two commonly used food preservatives, sodium benzoate and sodium metabisulphite were evaluated using the A. cepa assay. The parameters scored for the different concentrations of the compounds test...

The genus, Amaranthus, is a typical annual flowering plant valued as vegetables, grains and ornamentals. It exhibitsa high degree of interspecies variability and as such enhances biodiversity. Two common grain types (A. caudatus and A. cruentus) and three major weed types (A. hybridus, A. spinosus and A. viridis) were studied. Phenotypic traits wer...