Kevwe Esievo

• Doctor of Philosophy
• Research Fellow at National Institute for Pharmaceutical Research and Development, Abuja Nigeria

The methanol extracts of Brachiaria sabia, and Brachiaria marandu leaves were evaluated for its ability to scavenge free radicals, reduce ferric iron, and function as an iron chelator. The extracts were subjected to HPLC analysis. The two Brachiaria species possessed strong antioxidant activity, with B. marandu had a higher percentage (%) of phenol...

Natural dyes are becoming increasingly common for practical finishes that encourage an eco-friendly lifestyle. Natural dyes are renewable materials safe for the environment and do not cause toxicity, cancer, or allergic reactions. Transdermal Drug Delivery offers a pain-free method for delivering medication systemically by administering a drug form...

Background: Oxidative injury plays a pivotal impact in the development of human diseases, and it is a major component of the pathophysiology of several inflammation-linked human medical disorders. Objective: The focus of this study was to evaluate the cytotoxicity and antioxidant potential of the fruit of Lagenaria breviflora (Benth.) Roberty (LB)....

Aim: The aim of this research is to investigate the pharmacognostic characteristics, antioxidant potential, and anticholinesterase activity of Piliostigma thonningii (Schum.) Milne-Redh. This study seeks to evaluate its potential applications for neuroprotection and cognitive health enhancement. Place and Duration of Study: This study was carried o...

IntroductionPavetta crassipes is a medicinal plant with various documented biological activities. It has a folkloric use as an anti-viral therapy and pharmacologically documented anti-microbial activity. However, its immune modulatory property has not been explored. The study is designed to evaluate the phytochemical profile as well as the anti-oxi...

The purpose of this study is to investigate the knowledge, attitude, and practice of Nigerian health care practitioners regarding the use of herbal medications in the therapy of COVID-19. This was an online survey of Nigerian healthcare practitioners. To assess the level of relationship among research variables, descriptive statistics and chi-squar...

The outbreak of the COVID-19 pandemic came along with a lot of challenges including the absence of precautionary measures towards the prevention of the disease observed in market places around FCT. Also, herbal medicine practitioners became first point of call by locals even in advent of the disease. The perception regarding COVID-19 among herbal m...

In Nigerian ethnomedicine, various herbs including Thonningia sanguinea and Khaya senegalensis are part of medication (s) commonly used for viral infection (s) and inflammatory diseases. Preliminary investigations into their activities showed no significant viral inhibition. Their continuous use in natural antiviral remedies points to a possible im...

Background: The use of herbal medicine is believed to be on the increase. There is a gradual shift from the use of crude drugs to well packaged, developed and registered herbal medicinal product. Evidence of this trend in Nigeria is seen in the increasing number of herbal medicine products on store shelves. Objectives: The aim of the survey was to...

Most of the apples consumed across Nigeria are imported from South Africa, Europe and United States of America. Despite the epicuticular hydrophobic wax naturally produced by the fruit which makes it resistant to external spoilage factors, extra coating is usually employed by producers for protection against biotic and abiotic attack during storage...

Chemo-microscopic analysis of Lantana camara Linn revealed the presence of lignin, starch, cellulose, oxalate crystals, tannin, oils, proteins and absence of mucilage in the leaves while the flowers showed the presence of all tested metabolites except mucilage and lignin. The GC-MS analysis of volatile oils of different parts (leaves, flowers, frui...

Many claims from herbal medicines have been developed to manage COVID-19. Tests for identity and purity are important parameters in the quality assurance of herbal medicines. The aim of this study is to confirm the presence of Artemisia annua as a component of COVID-ORGANICS, an acclaimed herbal product for the management of COVID-19 in comparism w...

Introduction/Objective of study: Kigelia africana (Bignoniaceae) is enriched with bioactive constituents and has thus found various uses in African folklore. This study aims to evaluate the pharmacognostic, physicochemical, chromatographic and antiproliferative properties of K. africana.Methodology: Standard methods were used to determine the quali...

CHEMO-MICROSCOPY OF THE LEAVES AND GC-MS ANALYSES OF OILS FROM DIFFERENT PARTS OF LANTANA CAMARA LINN. GROWN IN NIGERIA *1Ugbabe, Grace E; 1Okhale, Samuel E; 1, 2 Thani Reshammah J; 1Esievo, KB and 1Fatokun OT. 1Medicinal Plant Research and Traditional Medicine (MPR and TM) Department, National Institute for Pharmaceutical Research and Developmen...

Most of the apples consumed across Nigeria are imported from South Africa, Europe and United States of America. Despite the epicuticular hydrophobic wax naturally produced by the fruit which makes it resistant to external spoilage factors, extra coating is usually employed by producers for protection against biotic and abiotic attack during storage...

The chemical composition of the essential oil of Dysphania ambrosioides and the antibacterial properties of the oil against two clinical isolates and two typed isolates (one each of Gram positive and Gram negative bacteria) of Bacillus subtilis, Staphylococcus aureus ATCC 25923; Escherichia coli, Pseudomonas aeruginosa ATCC 27853 was studied. The e...

Medicinal plants with anticancer properties have shown cytotoxicity and antiproliferative effects on fast growing meristematic cells. Abutilon mauritianum popularly called African mallow is a shrubby perennial plant with stems that usually become woody, used ethnomedicinally for managing viral infections and as an immune booster, and also to treat...

Ficus capensis Thumb (Moraceae) also known as the Cape fig plant belongs to the mulberry family and is a native of tropical Africa and the Cape Islands. Pharmacological studies have validated significant actions of different extracts as antimicrobial, relaxation of gastrointestinal tract, antioxidant and immune-booster agents, thus supporting some...

Introduction: Cassia tora Linn (Leguminosae-Caesalpinioideae), commonly known as Fotid in English and Tafasa in Hausa, is a perennial tree native to Africa. It has been reported to be used to manageskin infections, haemorrhoids, stomach ache and coughtraditionally. C. Tora leaves have been shown to possess anti-hepatotoxic, anti-allergic, anti-muta...

Annona senegalensis, also known as wild custard apple and wild soursop is a member of Annonaceae family. It is a fruit tree native to Senegal and found in semi-arid to subhumid regions of Africa, with a long history of traditional use. Numerous ethnomedicinal uses have been attributed to different parts of A. senegalensis, as well as its use as foo...