Kevin DamriCity University of New York - Bernard M. Baruch College | Baruch College · Department of Natural Sciences
Kevin Damri
Bachelor of Arts
About
7
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Introduction
Publications
Publications (7)
The TIM23 complex is a hub for translocation of preproteins into or across the mitochondrial inner membrane. This dual sorting mechanism is currently being investigated, and in yeast appears to be regulated by a recently discovered subunit, the Mgr2 protein. Deletion of Mgr2p has been found to delay protein translocation into the matrix and accumul...
Despite containing their own genome, mitochondria are not autonomous organelles. Over 1,146 of the known mitochondrial proteins are encoded in nuclear DNA and therefore must be imported from the cytosol. The process has been extensively studied and is known to involve several protein complexes spanning the outer and the inner mitochondrial membrane...
Cancer transformation involves reprograming of mitochondrial function to avert cell death mechanisms, monopolize energy metabolism, accelerate mitotic proliferation, and promote metastasis. Mitochondrial ion channels have emerged as promising therapeutic targets because of their connection to metabolic and apoptotic functions. This mini review disc...