Kenneth Mei Yee Leung

City University of Hong Kong | CityU · State Key Laboratory of Marine Pollution and Department of Chemistry

Fisheries resources in Hong Kong have been overexploited since the 1970s due to intensive bottom trawling and other fishing activities that have depleted stocks and destroyed marine habitat. To rehabilitate depleted fisheries resources, a permanent ban on trawling in Hong Kong territorial waters came into force on December 31, 2012. In order to det...

Conventionally, development of imposex, i.e., superimposition of male sexual characteristics on females, in marine neogastropods has been solely linked to exposure to synthetic organotin compounds, such as triphenyltin (TPT), in the marine environment. Here, our experimental results show that marine cyanobacteria can produce retinoic acids (RAs) an...

Microfibers of polyester and cotton might be significant for the transport and fate of chemical pollutants in the air due to the amounts emitted, as well as their capacities to sorb inorganic and organic compounds. It was hypothesized that household tumble driers could be atmospheric sources of these microfibers. This study quantified the number of...

Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the sca...

Ocean stratification plays a crucial role in many biogeochemical processes of dissolved matter, but our understanding of its impact on widespread organic pollutants, such as polycyclic aromatic hydrocarbons (PAHs), remains limited. By analyzing dissolved PAHs collected from global oceans and marginal seas, we found different patterns in vertical di...

Amphibians are sensitive biomonitors of environmental pollutants but reports regarding per- and polyfluoroalkyl substances (PFAS), a class of synthetic organofluorine substances, are limited. In this study, samples of water and Chinese toads (Bufo gargarizo) were collected in Chaohu Lake, China. Tissue-specific bioaccumulation characteristics of 39...

Due to their prevalence in urban contaminated water, the driving factors of organophosphate esters (OPEs) need to be well examined, and their related ecological impacts should include that of their transformation products (TPs). Additionally, a robust framework needs to be developed to integrate multiple variables related to ecological impacts for...

Halogenated flame retardants (HFRs) are a large class of chemical additives intended to meet flammability safety requirements, and at present, they are ubiquitous in the environment. Herein, we conducted the target analysis and suspect screening of legacy and novel HFRs and their metabolites in the blubber of finless porpoises (Neophocaena phocaeno...

The ban/elimination of legacy per- and polyfluoroalkyl substances (PFASs) has led to a dramatic increase in the production and use of various emerging PFASs over the past decade. However, trophodynamics of many emerging PFASs in aquatic food webs remain poorly understood. In this study, samples of seawaters and marine organisms including 15 fish sp...

Growing application of zinc oxide nanoparticles (ZnO-NPs) in global market has led to the concern over their potential environmental impacts. Filter feeders like mussels are prone to nanoparticles due to their superior filter-feeding ability. Temperature and salinity of coastal and estuarine seawaters often vary seasonally and spatially, and their...

Biochar-derived dissolved black carbon (DBC) molecules are dependent on the BC formation temperature and affect the fate of emerging contaminants in waters, such as polyvinyl chloride microplastic (MPPVC). However, the temperature-dependent evolution and MPPVC-interaction of DBC molecules remain unclear. Herein, we propose a novel DBC-MPPVC interac...

Legacy per- and polyfluoroalkyl substances (PFASs) have elicited much concern because of their ubiquitous distribution in the environment and the potential hazards they pose to wildlife and human health. Although an increasing number of effective PFAS alternatives are available in the market, these alternatives bring new challenges. This paper comp...

There is growing contamination of copper (Cu) in the marine environment, particularly after the ban of organotin compounds and the increase of the use of Cu-based antifouling paints. Although there are increasing research interests in temperature-dependent chemical toxicity to aquatic organisms, most existing studies focused on acute impacts of che...

Per- and polyfluoroalkyl substances (PFAS), widely used for industrial and commercial applications, are of worldwide concern due to their ubiquitous and persistent existence, possible toxic effects, and bioaccumulation potential. A good understanding of their environmental occurrence and fate can help assess the human exposure risk of PFAS. In this...

Coastal eutrophication and hypoxia remain a persistent environmental crisis despite the great efforts to reduce nutrient loading and mitigate associated environmental damages. Symptoms of this crisis have appeared to spread rapidly, reaching developing countries in Asia with emergences in Southern America and Africa. The pace of changes and the und...

Microplastics (MPs) and nanoplastics (NPs) are widely detected in food and the human environment. More studies have begun to pay attention to the influence of MPs and NPs on genetics; in particular, exposure of paternal generation to MPs and NPs on epigenetic inheritance and the offspring of animal models have attracted considerable interest. In th...

To better understand the formation process of biogenic and anthropogenic secondary organic aerosols (BSOA and ASOA) in the marine atmosphere under the background of global warming, aerosol samples were collected over three summers (i.e., 2014, 2016 and 2018) from the Bering Sea (BS) to the western North Pacific (WNP). The results showed that tempor...

Amphioxus are a small group of cephalochordates inhabiting shallow-water coastal areas in both tropical and temperate oceans. In Hong Kong, only one study of the species composition and distribution of amphioxus was conducted in the 2000s. The present study aimed to provide up-to-date information on the diversity, seasonal abundance and distributio...

Organophosphate esters (OPEs), as flame retardants and plasticizers, have been numerously explored regarding the occurrence and ecotoxicology. Given their toxicity, persistency and bio-accumulative potential, however, they may pose negative effects on ecosystems, regarding which is a growing global concern. Accordingly, the present review systemati...

Environmental context Excessive amounts of retinoic acids (RAs), the main derivatives of vitamin A, cause developmental abnormalities in animals, yet information on their fate in the marine environment is limited. This study investigated the degradation of all-trans-RA in seawater and found that over 90% was degraded and transformed in unfiltered n...

Recent epidemiological investigations report that environmental factors, such as exposure to harmful substances and stress related to unhealthy lifestyles, can result in health risks to organisms. The involvement of paternal exposure to chemicals and stresses, which leads to a negative impact on physiological responses and developmental processes i...

Emerging contaminants such as nanoplastics and nanoparticles likely experience similar environmental behaviours, fate and effects but our knowledge of their combined toxicity is scanty. This study, therefore, investigated the joint toxicity of polystyrene nanoplastics (PNPs) and zinc oxide nanoparticles (ZnO-NPs) to an ecologically important rotife...

Most organophosphate esters (OPEs) enter the marine environment through atmospheric deposition and surface runoff, yet the role of particle-mediated transport in their inputs and loss processes remains poorly understood. To fill this knowledge gap, samples of size-segregated atmospheric particles, suspended particulate matter (SPM) in seawater, and...

Biogenic secondary organic aerosols (BSOA) are important components of the remote marine atmosphere. However, the response of BSOA changes to sea ice reduction over the Arctic Ocean remains unclear. Here we investigated isoprene and monoterpenes secondary organic aerosol (SOAI and SOAM) tracers in three years of summer aerosol samples collected fro...

Parkinson’s disease (PD) is characterized by dopaminergic neurodegeneration in nigrostriatal and cortical brain regions associated with pathogenic α-synuclein (αSyn) aggregate/oligomer accumulation. LRRK2 hyperactivity is a disease-modifying therapeutic target in PD. However, LRRK2 inhibition may be associated with peripheral effects, albeit with u...

Transformation of organophosphate esters (OPEs) in natural ambient air and potential health risks from coexposure to OPEs and their transformation products are largely unclear. Therefore, a novel framework combining field-based investigation, in silico prediction, and target and suspect screening was employed to understand atmospheric persistence a...

Phthalate esters (PAEs) are representative additives used extensively in plastics. In this study, 15 PAEs were investigated at the eight riverine outlets of the Pearl River Delta (PRD). The total concentrations of Σ15PAEs, including both the dissolved and particulate phases, ranged from 562 to 1460 ng/L and 679 ng/L-2830 ng/L in the surface and bot...

The release of microplastics from sewage treatment works (STWs) into the oceans around coastal cities is well documented. However, there are fewer studies on the microplastic abundance in stormwater drains and their emissions into the coastal marine environment via sewage and stormwater drainage networks. Here, we comprehensively investigated micro...

Atmospheric particulate matter, especially in urban and industrial environments, can act as a source of different organic pollutants that can pose significant health impacts to residents. However, the pollution status and transport mechanisms of fine particle-bound polycyclic aromatic hydrocarbons (PAHs) in indoor and outdoor environments are uncer...

Per- and polyfluoroalkyl substances (PFAS) have been applied in numerous industrial and consumer products, the majority of which flow into waste management infrastructures (WMIs) at the end of their life cycles, but little is known about atmospheric releases of PFAS from these facilities. In this study, we addressed this key issue by investigating...

Excessive intake of retinoic acids (RAs) and the oxidative metabolites, 4-oxo-RAs, can lead to abnormal morphological development in animals. This study investigated spatiotemporal variations of concentrations and compositions of these compounds in Hong Kong's seawater and during algal blooms. Total concentrations of the studied compounds in seawat...

Organophosphate esters (OPEs) widely exist in the environment, raising increasing concerns about their potential health risks. This comprehensive review surveyed the occurrence of OPEs over the last decade in indoor microenvironments (i.e. residence, in-vehicle, office, and school/daycare center), outdoors, foodstuffs, drinking water, and human-rel...

Liquid crystal monomers (LCMs), commonly used in screens of electronic devices, have recently been identified as a group of emerging chemicals of concern associated with e-waste. They are potentially persistent, bioaccumulative, and toxic substances, and may pose a threat to the marine ecosystem. The Pearl River Estuary (PRE) receives organic conta...

Marine ecosystems are currently subjected to dual stresses of chemical pollution and climate change. Through a series of laboratory experiments, this study investigated the impact of exposure to chemical contaminant such as DDT or copper (Cu), in combination with cold or warm temperature extremes on the marine medaka fish Oryzias melastigma. The re...

Urban stormwater is an important pathway for transporting anthropogenic pollutants to water bodies. Phthalate esters (PAEs) are endocrine disruptors owing to their estrogenic activity and potential carcinogenicity and their ubiquitous presence has garnered global interest. However, their transportation by urban stormwater has been largely overlooke...

This study investigated the concentration fluctuation of organotin compounds in the Turbidity Maximum Zone (TMZ) of the Yangtze Estuary within a tidal cycle. Organotin concentrations varied greatly during the tidal cycle with dissolved organotins ranged from 39 to 682 ng Sn·L⁻¹ and 40–1588 ng Sn·L⁻¹, and particulate organotins ranged from 59 to 467...

Being a class of vitamin A’s main derivatives, retinoic acids (RAs) are important to animals’ growth and development. Previous studies demonstrated that exposure of excessive amounts of RAs would lead to malformation and abnormal development in aquatic animals such as amphibians and fishes. Currently, there are only limited toxicity data of RAs ava...

Strain KY-37 possessed the capacities of Zn(II)-resistance and BPA degradation. • The aerobic denitrifier, strain KY-37, showed strong auto-aggregation traits. • Strain KY-37 provided diverse functional groups to accelerate zinc removal. • The BPA degradation pathways were proposed through the intermediates. A B S T R A C T High concentrations of h...

Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the sca...

Phthalate esters (PAEs) are predominant additives in plastics, their widespread contamination in aquatic environments has raised global concern. Here, twelve plastic products were prepared as microplastics to investigate their release behaviors of PAEs. Six out of 15 PAEs were quantified after 14 days of incubation in water. The leaching potentials...

Significance Despite growing evidence of the deleterious effects on ecological and human health, little is known regarding the global occurrence of pharmaceuticals in rivers. Studies assessing their occurrence are available for 75 of 196 countries, with most research conducted in North America and Western Europe. This leaves large geographical regi...

Surgical masks (SMs) are the most commonly used personal protective equipment during the COVID-19 pandemic. Due to their vast use and inappropriate disposal worldwide, SMs could potentially cause serious microplastic (MP) pollution in coastal marine environments. This study aimed to investigate the kinetic release of MPs from polypropylene SMs (PP-...

In this study, the occurrence and distribution of 15 phthalate esters (PAEs) in seawater and sediment from the northern South China Sea (NSCS) were investigated for the first time to improve understanding on the contamination status of PAEs in this region. The concentrations of total PAEs (∑15 PAEs) were found to range from 68.8 to 1500 ng/L, 46.0...

Wastewater treatment plants (WWTPs) are important sources of antibiotic resistance genes (ARGs). Increasing attention has been paid to extracellular ARGs in cell-free form due to their horizontal gene transfer via transformation. However, the fate of the adsorbed form of extracellular ARGs that exist in extracellular polymeric substances (EPS) of a...

Circulating adiponectin (APN) levels decrease with age and obesity. On the other hand, a reduction in APN levels is associated with neurodegeneration and neuroinflammation. We previously showed that aged adiponectin knockout (APN−/−) mice developed Alzheimer’s like pathologies, cerebral insulin resistance, and cognitive impairments. More recently,...

Sewage treatment plants (STPs) are important in densely populated megacities like Hong Kong to control the release of harmful pollutants from households and industries into the receiving water bodies and maintain water quality for supporting various beneficial uses. This study investigated the occurrence of the teratogenic retinoic acids (RAs) and...

Water quality standards (WQS) are derived to give scientifically-robust and legally-binding guidance on acceptable risks of chemical contaminants with a view to protecting aquatic ecosystems and biodiversity. In China, anthropogenic chemical pollution of water bodies is a major threat to aquatic life. China, therefore, urgently needs to establish a...

Biodiversity of benthic brachyuran crustaceans have long been recorded from Hong Kong since the 1850s, and their assemblages reflect conditions of marine ecosystems. In the course of investigating potential recovery of fisheries resources in Hong Kong, performed from 2012 to 2018, after a territory-wide trawl ban in Hong Kong in effective since 31...

Crustaceans were among the most valuable fishery resources in Hong Kong. However, the unrestricted and intensive use of different fishing gears, especially bottom trawling, has led to the depletion of commercially important crustaceans in Hong Kong since the 1980s. This study investigated whether commercial crustaceans recovered after the implement...

Trawl fisheries have been shown to cause overfishing and destruction of benthic habitats in the seabed. To mitigate these impacts, a trawling ban has been enforced in Hong Kong waters since December 31, 2012 to rehabilitate the ecosystem and enhance fisheries resources. Previous studies demonstrated that reduced trawling activities would increase t...

The coronavirus disease 2019 (COVID-19) pandemic has brought unprecedented public health, and social and economic challenges. It remains unclear whether seasonal changes in ambient temperature will alter spreading trajectory of the COVID-19 epidemic. The probable mechanism on this is still lacking. This review summarizes the most recent research da...

Triphenyltin (TPT) is widely used as an active ingredient in antifouling paints and fungicides, and continuous release of this highly toxic endocrine disruptor has caused serious pollution to coastal marine ecosystems and organisms worldwide. Using bioassays and transcriptome sequencing, this study comprehensively investigated the molecular toxicit...

Maritime activities in the subarctic and Arctic Ocean are predicted to substantially increase in the future due to climate change and declining sea ice cover. Inevitably, the consequences will be seen in impacts on marine ecosystems in this region at many different levels, such as increased pollution load due to antifouling biocides, polycyclic aro...

The coronavirus disease 2019 (COVID-19) pandemic is challenging the current public health emergency response systems (PHERSs) of many countries. Although environmental factors, such as those influencing the survival of viruses and their transmission between species including humans, play important roles in PHERSs, little attention has been given to...

Bottom trawling, which is highly detrimental to seabed habitats, has been banned in some jurisdictions to mitigate the problems of habitat destruction and overfishing. However, most reports of ecosystem responses to trawling impacts originate from temperate latitudes, focusing on commercial species, and recovery of invertebrate macrobenthos from tr...

Nickel laterite ore deposits are becoming increasingly important sources of nickel for the global marketplace and are mainly found in tropical and sub‐tropical regions including Indonesia, the Philippines, Papua New Guinea, Cuba, and New Caledonia. There are few legislatively derived standards or guidelines for the protection of aquatic life for ni...