Keivan Javanshiri

Keivan Javanshiri
Lund University | LU · Department of Pathology

MD PhDc

About

13
Publications
1,178
Reads
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64
Citations
Citations since 2017
13 Research Items
64 Citations
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2017201820192020202120222023051015
Introduction
Keivan Javanshiri has a PhD from research conducted at the Department of Pathology in Lund, Lund University, Sweden where he focused on: 1 - Cardiovascular disease and risk factors in major neurocognitive disorders. 2 - Cardiac alpha-synuclein and its role in the cause of death in alpha-synucleinopathies. Keivan is also a MD at Skane University Hostpital in Lund, currently doing his residency in Oncology.
Additional affiliations
August 2018 - present
Lund University
Position
  • PhD Student
Description
  • Working within the neuropathology-group in Lund with a project about cardiovascular and cerebrovascular disease in dementia.
January 2017 - June 2018
Lund University
Position
  • Lecturer
Description
  • Lectured and educated MD students in autopsy and anatomy as an eminent senior student. Responsible for the education and management of other student tutors.
Education
August 2018 - August 2022
Lund University
Field of study
  • Translational Pathology
January 2013 - January 2019
Lund University
Field of study
  • Medicine

Publications

Publications (13)
Article
Full-text available
The purpose of this study was to investigate the cause of death in subjects with α-synucleinopathies (ASs) and the confirmed presence of cardiac α-synuclein (α-syn), compared to non-AS disorders in a neuropathologically confirmed cohort. In total, 78 neuropathologically confirmed AS cases positive for cardiac α-syn were included in the study. Indiv...
Thesis
Full-text available
The prevalence and association of cardiovascular disease on autopsy, hypertension and type 2 diabetes mellitus in Alzheimer's disease, Lewy body disease, mixed dementia, and vascular dementia. The prevalence of cardiac alpha-synuclein and its role in the cause of death in alpha-synucleinopathies.
Article
Full-text available
Background There is a need for the development of accurate, accessible and efficient screening instruments, focused on early-stage detection of neurocognitive disorders. The Geras Solutions cognitive test (GSCT) has showed potential as a digital screening tool for cognitive impairment but normative data are needed.Objective The aim of this study wa...
Article
Full-text available
Background: There are few studies on the locus coeruleus (LC) in frontotemporal lobar degeneration (FTLD) and the potential differences in the LC related to the underlying proteinopathy. Objective: The aim of this study was to investigate the LC in FTLD subgroups. Methods: Neuropathological cases diagnosed with FTLD were included. The subgroup...
Article
Full-text available
Background: Alpha-synucleinopathies (AS) are characterized by pathologic aggregations of alpha-synuclein (α-syn) in the central nervous system, and comprise dementia with Lewy bodies, Parkinson's disease, and multiple system atrophy. Previous studies on AS have reported findings of α-syn pathology in the peripheral nervous system of multiple organ...
Article
Full-text available
Background: Research concerning the potential roles of cardiovascular disease (CaVD) and diabetes mellitus (DM) as risk factors for Lewy body disease (LBD) is limited. These disorders are, however, established risk factors for vascular dementia (VaD) and have been proposed as risk factors for Alzheimer’s disease (AD). Objective: The aim of this stu...
Experiment Findings
We examined and compared the prevalence of atherosclerosis in the coronary arteries and the aorta, heart hypertrophy, heart infarction, nephrosclerosis, hypertension and diabetes in neuropathologically confirmed cases of Alzheimer´s disease, vascular dementia and mixed dementia respectively. The macro- and microscopical findings were obtained thro...
Experiment Findings
We examined and compared the prevalence of atherosclerosis in the coronary arteries and the aorta, heart hypertrophy, heart infarction, nephrosclerosis, hypertension and diabetes in neuropathologically confirmed cases of Alzheimer´s disease, vascular dementia and mixed dementia respectively. The macro- and microscopical findings were obtained thro...
Experiment Findings
We examined and compared the prevalence of atherosclerosis, heart hypertrophy, heart infarction, nephrosclerosis, hypertension and diabetes in neuropathologically confirmed cases of Alzheimer´s disease, vascular dementia and mixed dementia respectively. The macro- and microscopical findings were obtained through autopsy reports and neuropathologic...
Experiment Findings
We examined and compared the prevalence of atherosclerosis, heart hypertrophy, heart infarction, nephrosclerosis, hypertension and diabetes in neuropathologically confirmed cases of Alzheimer´s disease, vascular dementia and mixed dementia respectively. The macro- and microscopical findings were obtained through autopsy reports and neuropathologic...
Article
Full-text available
Background: Alzheimer's disease (AD) is the most prevalent cause of dementia with vascular dementia (VaD) being second alongside with mixed AD and VaD, according to some. For some time, it has been proposed that cardiovascular disease (CaVD), hypertension, and diabetes mellitus (DM), which are known risk factors for VaD, also are associated with a...

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Projects

Project (1)
Project
The goal of this project is to: 1- Increase the knowledge of different risk factors and cardiovascular disease in major neurocognitive disorders and specifically their association with Alzheimer's disease and Lewy body disease. Additionally, we will investigate the prevalence of cardiac alpha-synuclein, its effect on cardiac function, and the cause of death in alpha-synucleinopathies. All research will be based on individuals who have undergone a thorough neuropathological examination.