Kazemi Nezhad

Kazemi Nezhad
Shahid Chamran University of Ahvaz | scu · Department of Genetics

PhD (Dr.rer.nat)

About

15
Publications
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Publications

Publications (15)
Article
Breast cancer is one of the most prevalent known cancers in women with the incidence rate of annually 7000 cases in Iran. MicroRNAs (miRNAs) are a group of non-coding RNAs with 20–25 nucleotides length, which can effect on cancer development. There is low information about the influence of anti-cancer drugs on the expression levels of miRNAs. The p...
Article
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Background: Colorectal cancer (CRC), is the third most common cancer type. MicroRNAs and their roles in cancer progression have gained considerable attention in the scientific community. miR-485-3p has been identified to be abnormally expressed in different types of cancer, but its expression level, biological function, and underlying pathways are...
Article
Systemic sclerosis (SSc) and Rheumatoid arthritis (RA) are types of autoimmune diseases. Susceptibility to these diseases depends on a complex interaction between environment and genetic factors. It is likely that common underlying genes are involved in mentioned diseases. In recent years, researchers focused on the genes encoding immune regulatory...
Article
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Linkage studies and epidemiological findings indicate that some possible genes in schizophrenia (SCZ) and bipolar mood disorder (BPD) are common. Numerous evidences for linkage of two diseases on chromosome 22 have been found. These findings suggest that one or more genes in the 22q11.21 region may be involved in the development of both disorders....
Article
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Schizophrenia is a complex disorder with polygenic inheritance. The MTHFR gene (OMIM: 607093) plays an important role in the folate metabolism. It has been suggested that C677T (rs1801133) and A1298C (rs1801131) genetic polymorphisms in the MTHFR gene lead to the decreased activity of the methylenetetrahydrofolate reductase enzyme which may have si...
Article
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To estimate the genetic diversity of the hawksbill turtle populations, the mitochondrial DNA control region was used as a matrilineal marker. Captured turtles (69 samples) were obtained from three different islands in the Persian Gulf. From all the samples DNA was isolated. Primers were selected based on a specific sequence in control region of mit...
Article
Diabetes Mellitus is characterized by chronic hyperglycemia and associated with an increased production of reactive oxygen species (ROS). Oxidative stress is the result of accumulation of free radicals in tissues which specially affects beta cells in pancreas. Glutathione S-transferases (GSTs) are a family of antioxidant enzymes that include severa...
Article
In Iranian coastal waters of the Persian Gulf as a result of both direct and indirect human impacts such as uncontrolled or illegal hunting, sea turtle populations are drastically declining. Information on the genetic structure of marine species is essential for stock enhancement programs. To estimate the genetic diversity of the hawksbill turtle p...
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Abstract Background: Spinal muscular atrophy (SMA) is the second mo st common lethal autosomal recessive disease. It is a neuromuscular disorder caused by degenerative of lower motor neurons and occasionally bulbar neurons leading to progressive limb paralysis and muscular atrophy. The SMN1 gene is recognized as a SMA causing gene while NAIP has be...
Article
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common hereditary enzymatic disorders in human, increases the vulnerability of erythrocytes to oxidative stress. It is also characterized by remarkable molecular and biochemical heterogeneity. According to previous investigations, G6PD Cosenza (G1376C) is a common G6PD mutation...
Article
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most frequent genetic enzymatic disorder in humans. G6PD is inherited as an X-linked recessive gene and encodes a vital housekeeping enzyme. The predominant variant of G6PD is named Mediterranean, often associated with Favism. Most G6PD-Mediterranean subjects also have a silent trans...
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C untilfurther use. Genomic DNA was extracted from whole bloodof the G6PD deficient subjects using DNA extraction kit(Roche Molecular Biochemicals, Switzerland). All sampleswere analysed by PCR-RFLP method for the G1003A muta-tion in exon 9 which is characteristic of G6PD Chatham. ForPCR reaction, the forward and reverse primers were: 5 -CAAGGA GCC...
Article
Full-text available
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most frequent genetic enzymatic disorder in human, which is inherited as an X-linked gene. It encodes a housekeeping enzyme, which is vital for cell survival. Accord-ing to previous investigations, Mediterranean mutation (C563T) of g6pd gene is the most prevalent mutation in som...
Article
Full-text available
Oenocytes of the cricket, Gryllus bimaculatus, were characterized by a continuously high secretion of ecdysteroids over several hours. A factor extracted from heads of the male adults caused the oenocytes to enhance immunoreactive ecdysteroid secretion in vitro. This factor was isolated by high performance size exclusion chromatography. Its molecul...