Katia M'Bailara

Katia M'Bailara
University of Bordeaux

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94
Publications
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Publications

Publications (94)
Article
Background The FACE-BD cohort is an observational cohort of individuals with bipolar disorders (BD) who benefited from a systematic evaluation with evidence-based treatment recommendations and who were followed-up every year for 3 years in France. The objectives were to describe the lifetime course of BD, associated psychiatric and somatic comorbid...
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In patients with bipolar disorder (BD), pain prevalence is close to 30%. It is important to determine whether pain influences BD course and to identify factors associated with pain in BD in order to guide BD management. This naturalistic, prospective study used data on 880 patients with BD from the French FACE-BD cohort who were divided into two gr...
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In order to determine family functioning in the treatment of adults with bipolar disorders, guidelines are needed regarding the way family functioning may be assessed. The present systematic review aims to investigate how family functioning is assessed in this context. Following PRISMA guidelines, a total of 29 studies were reviewed. Results showed...
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Objectives: Childhood maltreatment, also referred as childhood trauma, increases the severity of Bipolar Disorders (BD). Childhood maltreatment has been associated with more frequent mood recurrences, however mostly in retrospective studies. Since scarce, further prospective studies are required to identify whether childhood maltreatment may be as...
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Résumé Introduction Le tabac et l’alcool sont les deux facteurs de risques principaux évitables de survenue de cancer et ont un impact non négligeable sur la mortalité, notamment chez les personnes atteintes de cancer du sein. Peu de recherches s’intéressent aux usages de substances psychoactives des femmes traitées pour un cancer du sein. Cette é...
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Objectives High rates of non-right-handedness (NRH) and mixed-handedness exist in neurodevelopmental disorders. Dysfunctional neurodevelopmental pathways may be implicated in the underlying pathophysiology of bipolar disorders (BD), at least in some subgroups. Yet little is known about correlates of NRH and mixed-handedness in BD. The objectives of...
Article
Mental imagery is often described as “seeing with the mind's eye” as it refers to perceptual experiences of sensory information in the absence of external sensory input (Kosslyn, Ganis, & Thompson, 2001). Mental imagery is known to be strongly related to emotion and is used in the context of therapy for the treatment of mood disorders, in particula...
Article
Objectives: The comorbidity of alcohol use disorder (AUD) and bipolar disorder (BD) has been repeatedly associated with poorer clinical outcomes than BD without AUD. We aimed to extend these findings by focusing on the characteristics associated with the sequence of onset of BD and AUD. Methods: 3,027 outpatients from the Fondamental Advanced Ce...
Article
OBJECTIVE To examine which characteristics predict the time to a first mood recurrence at three years in Bipolar Disorder type I (BD-I) and type II (BD-II). METHODS Individuals with BD were followed up to 3 years. Turbull’s extension of the Kaplan-Meier analysis for interval-censored data was used to estimate the cumulative probability of recurren...
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Background Postpartum period is associated with an increased risk of bipolar disorder diagnosis and relapse, mainly major depressive episode. Onset during this period might be associated with specific characteristics. Aim To compare the socio-demographic and clinical characteristics of parous women presenting with bipolar disorder and an index dep...
Article
Background: Bipolar disorder (BD) is a chronic and severe mental illness. It requires a non-discontinued pharmacological treatment to prevent mood recurrences but nonadherence to medication is frequent. To this date, medication adherence in BD has been mostly evaluated in cross-sectional studies and often considered as a stable trait. We aimed to s...
Poster
Objectifs : L’activation d’images mentales, renvoyant à la capacité de « voir ou entendre avec son esprit » (Kosslyn et Ganis, 2003) peut être associée à de fortes réponses émotionnelles (Ji et al., 2016). Cependant, si l’image mentale est décrite comme étant le langage des émotions immédiates (Goodwin et Holmes, 2009), la relation entre le contenu...
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Background A crucial health issue is to understand the remission heterogeneity of Bipolar Disorders by considering symptomatology as well as functioning. A new perspective could be elements of the construction of individual identity. This exploratory study aimed to explore the remission heterogeneity of patients with BD in terms of Early Maladaptiv...
Article
Objective We aimed at identifying distinct trajectories of functioning and at describing their respective clinical characteristics in a cohort of individuals with bipolar disorders. Methods We included a sample of 2351 individuals with bipolar disorders who have been followed-up to 3 years as part as the FondaMental Advanced Centers of Expertise i...
Article
Au 6e rang mondial des handicaps [1], les troubles bipolaires concernent 2,4 % de la population [2]. On estime à 10 ans en moyenne le temps écoulé entre un premier épisode du trouble et l’instauration d’un traitement adapté [3]. La Fondation FondaMental a créé le réseau des centres experts (CEF) avec pour ambition d’éviter l’aggravation des trouble...
Article
Introduction La normothymie n’est pas indemne de toute perturbation émotionnelle, les patients ayant un trouble bipolaire rapportent en effet une labilité émotionnelle, une réactivité émotionnelle intense [1] et des difficultés dans la régulation des émotions [2]. Cependant, une hétérogénéité de profils existe et peu de travaux se sont attachés à c...
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Introduction Nombre de patients ayant un trouble bipolaire ont un haut niveau de handicap en période intercritique (Roux et al., 2017). Comprendre cette hétérogénéité clinique sur les plans symptomatique et fonctionnel est un enjeu clinique important. Les schémas précoces inadaptés (SPI) sont une piste pertinente à explorer. En effet, ce sont des p...
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Objectives: Clinical heterogeneity during euthymic states is a crucial issue in bipolar disorders. Indeed, actual data are not sufficient to understand why some patients are unharmed by subthreshold symptoms and have functional impairments whereas others have a functional remission but have subthreshold symptoms. Based on the Ball model, cognitive...
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Objectives: The patient with bipolar disorder and his family are caught in a reciprocal interaction: on one hand, the pathology leads to family sufferings and on the other hand, family behavior affects the disease of the patient and its development. Therefore, it seems of core importance that the psychologist should work with the family on their pe...
Article
Les difficultés d’observance médicamenteuse chez les personnes souffrant de troubles bipolaires sont fréquentes et ont un fort retentissement sur leur fonctionnement et leur qualité de vie. Bien qu’il soit cliniquement admis que la qualité de l’observance fluctue chez les personnes souffrant de trouble bipolaire, aucune étude ne s’est encore intére...
Article
The aim of this study was to assess the respective weight of individual and environmental factors on quality of life (Qol) of parents of children with autism spectrum disorders (ASD). Few studies have investigated both individual and environmental predictors of Qol but to our knowledge, none of them has considered the child's and parents' character...
Article
Background Cognitive deficits are a well-established feature of bipolar disorders (BD), even during periods of euthymia, but risk factors associated with cognitive deficits in euthymic BD are still poorly understood. We aimed to validate classification criteria for the identification of clinically significant cognitive impairment, based on psychome...
Article
Objective Remitted bipolar disorder (BD) patients frequently present with chronic mood instability and emotional hyper‐reactivity, associated with poor psychosocial functioning and low‐grade inflammation. We investigated emotional hyper‐reactivity as a dimension for characterization of remitted BD patients, and clinical and biological factors for i...
Article
Therapeutic Education (TE) is now acknowledged as a useful intervention by French law Hospital, Patients, Health and Territory and the public health code. Yet despite the guidelines, the implementation of this model is still not very widespread as is also the case of the support devices of parents of children with Autism Spectrum Disorder (ASD). Th...
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Résumé La dépression constitue à l’heure actuelle un réel problème de santé publique associé à des coûts de santé très élevés et à des répercussions importantes dans la vie du patient et de son entourage. Un des enjeux est d’identifier les prises en charge les plus adaptées en fonction du stade de la maladie et de préciser la place des différents a...
Article
Résumé Au quotidien, les Troubles du spectre de l’autisme (TSA) nécessitent des aménagements spécifiques pour la personne handicapée, mais aussi un accompagnement pour les proches-aidants. Dans cette optique, le dernier Plan Autisme 2013–2017 insiste sur la nécessité de former les familles, afin notamment d’éviter les situations d’épuisement. L’édu...
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Objectives: Poor adherence to medication is frequent in bipolar disorder (BD) and has been associated with several factors. To date, the relationship between low adherence and neuropsychological functioning in BD is still unclear. As age and neuropsychological functioning might have opposing influences on adherence, our aim was to investigate this...
Article
Objectives: Inter-episode mood instability has increasingly been considered in bipolar disorder. This study aimed to investigate emotional reactivity as a major dimension for better characterizing remitted bipolar patients with subthreshold mood symptoms and functional status. This study also aimed to investigate whether high-sensitivity C-reactiv...
Article
Background: Childhood trauma has been associated with a more severe clinical expression of bipolar disorder (BD). However, the results that specifically associated traumatic events and psychotic features in BD have been inconsistent, possibly due to the low resolution of the phenotypes being used. Methods: 270 normothymic patients with BD comple...
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This study aimed to identify parental stress predictors in ASD by considering individual and environmental factors in an ecological approach. Participants were 115 parents of children with ASD aged from 3 to 10 years. Multiple regression analyses were conducted to determine the best predictors of parental stress among child-related, parent-related...
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Raising a child with an autism spectrum disorder (ASD) implies significant stress levels and changes in family functioning. Most studies deal with parental difficulties, whereas those focusing on parental self-reported support needs related to ASD are fewer, especially in France. Our objective was to explore in a French sample the needs of parents...
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Autism Spectrum Disorders (ASD) are associated with higher levels of anxiety for parents [1]. Provide medical information about autism etiology is the first step to help parents to understand the child disorder and to cope with it. The medical current community accepts that autism is a neurodevelopmental disorder in which genes play a role but that...
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La réactivité émotionnelle est définie par l’intensité émotionnelle avec laquelle un individu réagit à son environnement. Il est désormais admis que les patients ayant reçu un diagnostic de trouble bipolaire ont, en moyenne, une réactivité émotionnelle de base plus intense que les sujets n’ayant pas la pathologie [1–3]. Afin d’affiner cette observa...
Article
Vivre au quotidien avec un trouble bipolaire ou vivre avec un patient atteint d’un trouble bipolaire génère un stress familial intense [1]. Les recommandations de la Haute Autorité de santé (HAS) et le développement parallèle de l’éducation thérapeutique du patient proposent 3 axes prioritaires de prise en charge des aidants familiaux : l’informati...
Article
La période intercritique des troubles bipolaires, jusque récemment considérée comme indemne de troubles thymiques avérés fait l’objet depuis quelques années d’une attention particulière dans les recherches scientifiques. Les travaux montrent que nombre de patients rapportent des symptômes résiduels, une hyperréactivité émotionnelle [1], des difficu...
Article
L’accompagnement des parents d’enfants avec un trouble du spectre autistique (TSA) présente de multiples enjeux tant d’un point de vue clinique [3] que dans une perspective médico-économique [1]. Le nouveau plan Autisme 2013–2017 ainsi que les recommandations de la Haute Autorité de santé de 2012 insistent sur la nécessité de proposer un accompagne...
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To assess the association between mind wandering (thinking unrelated to the task at hand) and the risk of being responsible for a motor vehicle crash. Responsibility case-control study. Adult emergency department of a university hospital in France, April 2010 to August 2011. 955 drivers injured in a motor vehicle crash. Responsibility for the crash...
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To better explore the clinical heterogeneity of bipolar mood states, we developed a dimensional scale for assessing all mood episodes (depressive, hypomanic, manic, mixed states) using the same tool. The Multidimensional Assessment of Thymic States (MATHYS) (Henry et al., 2008) provides two scores, a total score measuring a level of activation and...
Article
Objective: Duration of untreated illness represents a potentially modifiable component of any diagnosis-treatment pathway. In bipolar disorder (BD), this concept has rarely been systematically defined or not been applied to large clinically representative samples. Method: In a well-characterized sample of 501 patients with BD, we estimated the d...
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BACKGROUND: Pattern analysis can aid understanding of trajectories of symptom evolution. However, most studies focus on relatively homogeneous disorders with a restricted range of outcomes, prescribed a limited number of classes of medication. We explored the utility of pattern analysis in defining short-term outcomes in a heterogeneous clinical sa...
Article
Assessment of emotional reactivity, defined as rapid emotional responses to salient environmental events, has been neglected in mood disorders. This article reviews data showing the relevance of using emotional reactivity to better characterize bipolar mood episodes. We reviewed clinical data on emotional reactivity during all phases of bipolar dis...
Article
The clinical presentation, course, and comorbidities of bipolar disorder type I are highly heterogeneous, and this variability remains poorly predictable. Certain onset characteristics (eg, age and polarity at onset) may delineate subgroups differing in clinical expression and outcome. We retrospectively investigated the association between both ag...
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Objective: The clinical presentation, course and comorbidities of bipolar disorder type I (BD1) are highly heterogeneous and this variability remains poorly predictable. Certain onset characteristics (e.g. age and polarity at onset) may delineate subgroups differing in clinical expression and outcome. Method: We investigated the association between...
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Despite its obvious importance in mood disorders, characterization of emotional reactivity has been neglected in bipolar disorders. Concerning manic states and the current classification, the main criterion is the presence of an elevated or expansive mood. In contrast to this characteristic and often prolonged mood state, emotional reactivity refer...
Article
EUthymic states in bipolar disorders are generally considered to be devoid of severe symptoms. However, bipolar patients present subsyndromal symptoms for half of their life, and often have comorbid psychiatric disorders. If we go beyond the concept of temperamental features, can we identify certain emotional characteristics distinguishing normothy...
Article
Group-based trajectory modeling (GBTM) is a statistical method created to explore the heterogeneity of clinical groups based on their longitudinal outcomes by identifying distinct trajectories of change. This model can be applied to assess heterogeneity in responses to treatment. This pilot study explored the relevance of the GBTM associated with t...
Article
Objectives: Mood state heterogeneity in bipolar disorder leads to confusion in diagnosis and therapeutic strategies. Recently, the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) showed that two-thirds of bipolar-depressed patients had concomitant manic symptoms, these characteristics being linked to a more severe form of b...
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Background Euthymic states in bipolar disorders are usually considered to be lacking serious psychiatric disorders. Moreover, recent results prove the need to take an interest in a potential emotional dysregulation during these intercrisis periods. Therefore, it seems relevant not only to focus on the emotions tonality (sadness/euphoria) felt by pa...
Article
Full-text available
Euthymic states in bipolar disorders are usually considered to be lacking serious psychiatric disorders. Moreover, recent results prove the need to take an interest in a potential emotional dysregulation during these intercrisis periods. Therefore, it seems relevant not only to focus on the emotions tonality (sadness/euphoria) felt by patients, but...
Article
Los trastornos bipolares suelen definirse por estados de humor alternativos, pero una caracterización más precisa del periodo eutímico podría proporcionar una comprensión adicional de la fisiopatología de estos trastornos. Sorprendentemente, pocos estudios han investigado las dimensiones afectivas esenciales en pacientes bipolares eutímicos. En el...
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Full-text available
Background: Normothymic states in bipolar disorders are generally considered to be devoid of severe symptoms. However, bipolar patients present subsyndromal symptoms for half of their lives, and often have comorbid psychiatric disorders. If we go beyond the concept of temperamental features, can we identify certain emotional characteristics distin...