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22
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Introduction
Current institution
Leipzig
Current position
- Medical Doctor
Publications
Publications (22)
In obesity, hypertrophic adipocytes secret high amounts of adipocytokines resulting in low-grade inflammation- amplified by infiltrating pro-inflammatory macrophages, oxidative stress, hypoxia and lipolysis. It is known, that these chronic pro-inflammatory conditions support the development of type II diabetes and cardio vascular diseases, while me...
Background:
Extracorporeal photopheresis (ECP) is commonly performed via peripheral venous access catheter. If this is not possible, a tunneled central venous catheter may be considered. However, this access mode may be associated with high complication rates. Port catheters and permanent arteriovenous fistulas in principle could serve as alternat...
Impaired cross talk between keratinocytes and immune cells is believed to contribute to the pathogenesis of chronic inflammatory skin diseases, such as psoriasis. We have previously identified keratinocytes as a rich source of the serpin protease inhibitor vaspin (serpinA12), originally described as an adipokine in adipose tissue. Herein, we studie...
An accurate characterization of glioma heterogeneity is essential when determining tumor grade and the most appropriate therapy target. Non-invasive imaging modalities such as MR perfusion imaging (PWI) and 2D proton MR spectroscopic imaging (MRSI) can provide functional and metabolic information about the tumor to assist in this task. Using a voxe...
Background:
Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown aetiology which can manifest in ulcerative skin lesions and is widely recognised in association with diabetes. We evaluated in total 100 patients to improve knowledge about the epidemiology and clinical course of NL. Additionally we focused on treatment options acco...
Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown etiology which can manifest in ulcerative skin lesions and is widely recognised in association with diabetes mellitus. Our aim was to improve knowledge about the epidemiology and clinical course of NL and evaluate treatment approaches. This multicentre retrospective study covere...
Psoriasis is an inflammatory skin disease often associated with obesity. The anti-inflammatory adipokine vaspin, a suggested serine proteinase inhibitor of the serpin family, is discussed as a new link between inflammation and obesity. Here, we demonstrate that - different from healthy controls - vaspin serum levels in patients with psoriasis were...
ejd.2011.1627 Auteur(s) : Katharina Vester1 katharina.vester@medizin.uni-leipzig.de, Regina Treudler1, Uwe Paasch1, Cornelia Becker2, Andre Liebmann3, Jan Christoph Simon1, Claudia Wickenhauser4, Manfred Kunz1 1 Departments of Dermatology, Venereology and Allergology, 2 Hematology, Oncology and Hemostaseology 3 Radiation Oncology, and 4 Institute o...
This dissertation aims at the investigation of the relationship between metabolites concentration and perfusion parameters of MR-imaging in the evaluation of primary malign brain tumours using ROI-analysis and pixel-by-pixel-analysis. Objective of this study on 31 patients is to analyse whether both spectroscopic imaging and MR perfusion imaging in...
