Karolina L. Zapadka

University of Cambridge | Cam · Department of Chemistry

The number of biological therapeutic agents in the clinic and development pipeline has increased dramatically over the last decade and the number will undoubtedly continue to increase in the coming years. Despite this fact, there are considerable challenges in the development, production and formulation of such biologics particularly with respect t...

Abcam plc. - headquartered in Cambridge, UK, employs over 1,000 people across twelve locations globally and serves researchers and clinical communities in over 130 countries. The company provides highly validated antibodies, other binders and assays. Their catalogue offers more than 120,000 products and multi-lingual technical support. Abcam is a l...

The Milner Therapeutics Institute was officially launched on the 14th of March 2016 at Jesus College, University of Cambridge, UK. It is a new Institute that sits jointly within the School of Biological Sciences and the School of Clinical Medicine at the University of Cambridge, UK. The Institute has been made possible by a donation from an entrepr...

Innovation & Impact is an interdisciplinary Scientific Technology and Business Journal. The Journal presents exciting technology profiles, case studies and invited papers concerning the process of innovation, valorisation and its impact on society and Global Economy. The journal mission is to promote innovation & valorization. We aim to inspire res...

Selvita is an integrated drug discovery biotechnology company with HQ and laboratories in Krakow, Poland. The company has two primary focus areas: to serve the drug discovery market as a customer centric provider of high quality, integrated drug discovery services and as a drug discovery company engaged in the research and development of breakthrou...

Aggregation and amyloid fibril formation of peptides and proteins is a widespread phenomenon. It has serious implications in a range of areas from biotechnological and pharmaceutical applications to medical disorders. The aim of this study was to develop a better understanding of the mechanism of aggregation and amyloid fibrillation of an important...

Aggregation and amyloid fibril formation of peptides and proteins is a widespread phenomenon. It has serious implications in a range of areas from biotechnological and pharmaceutical applications to medical disorders. The aim of this study was to develop a better understanding of the mechanism of aggregation and amyloid fibrillation of an important...

This study has worked towards a better understanding of the mechanism of the aggregation and amyloid fibrillation of a model peptide (GLP-1). GLP-1 in a naturally occurring incretin hormone, where the biologically active form consists of 31 residues, which together with insulin and glucagon regulate the blood sugar levels in humans. Here, a variety...

The present invention provides an aqueous solution comprising an antibody protein at a concentration of at least about 10 mg/mL and a stabilizing amount of polyethyleneimine.

Single chains of the conjugated polymer MEH-PPV (poly(2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylenevinylene)) were studied with wide-field fluorescence microscopy (dispersion in inert polymer matrices) and with fluorescence correlation spectroscopy (chloroform solution). The fluorescence yield of individual molecules in matrices was found to be 1-2...