Karol Andrea Mendez

• University of Applied and Environmental Sciences

Background Medication reconciliation is defined as ‘‘the process of identifying the most accurate list of all medications a patient is taking, including the name, dosage, frequency, and route of each medication, and using this list to provide the correct medications for the patient anywhere within the health care system”. It has been demonstrated t...

Background adverse drug reactions (ADRs) are events that may seriously affect the health of people who use drugs for therapeutic purposes.¹ In the case of patients with rheumatic diseases the existence of comorbidities, the use of DMARDs, or polymedication may increase the risk of developing any type of adverse drug reaction.² Objectives We aim to...

Background Osteoarthritis (OA) is a common joint disorder and may occur in any synovial joint in the body, the condition is common in hands, knees, hips and spine. Diacerein is a antraquinone derivate has shown the inhibition of cytokine interleukine 1-B (1). A Cochrane review published in in 2014 showed that diacerein could be effective for this c...

Background Immunosuppressants such as mycophenolate are widely used in people with systemic lupus erythematosus (SLE), but not all are specifically licensed by FDA, EMA (1) and in the case of Colombia the Regulatory Agency for Food and Drugs (INVIMA) has not approved it for this indication, only for the prevention of the rejection of some transplan...

Background Tofacinitib is an oral Janus Kinase for the treatment for rheumatoid arthritis (RA). The efficacy and safety of tofacitinib in monotherapy or in combination with other DMARDs has been demonstrated in clinical trials. However previous studies had report hematological changes and infections associated to the use of this medication (1, 2);...