Karl-Heinz Kunzelmann

Karl-Heinz Kunzelmann
Ludwig-Maximilians-University of Munich | LMU · Department of Operative Dentistry and Periodontology

Prof. Dr.

About

276
Publications
26,405
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5,268
Citations
Additional affiliations
September 1992 - present
University Hospital München
Position
  • Managing Director
Description
  • Research, undergraduate and postgraduate education, clinical dentistry and dental science

Publications

Publications (276)
Article
Full-text available
Objectives This in vitro study aimed to investigate the optical attenuation of light at 405, 660 and 780 nm sent through sound and carious human enamel and dentin, including respective individual caries zones, as well as microscopically sound-appearing tissue close to a carious lesion. Materials and methods Collimated light transmission through se...
Preprint
Background The aim of this study was to evaluate the postbrushing tooth-whitening effect of toothpaste containing hydroxyapatite nanoparticles (nano-HAPs). The impact of the concentration on the whitening performance of nano-HAP toothpaste was also investigated. Methods Two concentrations of nano-HAP (10 wt% and 1 wt%) were incorporated in nonabras...
Article
Full-text available
Background This study evaluated the adhesion and whitening efficacy of a mixture of hydroxyapatite and P11-4 self-assembling peptide (HAP-peptide) on bovine enamel after pre-treatment with low-concentrated sodium hypochlorite (NaOCl). Methods Fifty-two caries-free bovine incisors were selected. 50 teeth were randomly allocated to five groups (n =...
Article
Objectives The fracture resistance of ultrathin computer-aided design and computer-aided manufacturing (CAD/CAM) occlusal veneers with different preparation designs was investigated under cycling mechanical loading and via finite element analysis (FEA). Methods Eighty molars were prepared with a circular enamel ring until complete exposure of the...
Article
Full-text available
Objectives This in vitro study analysed potential of early proximal caries detection using 3D range data of teeth consisting of near-infrared reflection images at 850 nm (NIRR). Materials and methods Two hundred fifty healthy and carious permanent human teeth were arranged pairwise, examined with bitewing radiography (BWR) and NIRR and validated...
Article
Purpose: To investigate the tooth-whitening effects of mouthrinses containing different sizes of hydroxyapatite (HAP) particles after prolonged application time and compare them with a commercial whitening mouthrinse. Methods: 50 bovine incisors were stained and randomly distributed into five groups: the HAP groups with 3 µm, 200 nm and 50 nm pa...
Article
Objectives: Upon initial proximal wall construction, the favorable C-factor of class-II cav- ities may become unfavorable. This study investigated the application method on bulk-fill resin composite polymerization shrinkage. Methods: Occluso-proximal class-II cavities were prepared in 40 molars and bonded with a self-etch adhesive (Adhese Universal...
Article
Full-text available
Objectives This investigation evaluated the effect of flowable liners beneath a composite restoration applied via different methods on the pattern of shrinkage vectors. Methods Forty molars were divided into five groups ( n = 8), and cylindrical cavities were prepared and bonded with a self-etch adhesive (AdheSe). Tetric EvoCeram Bulk Fill (TBF) w...
Article
The aim of the study was to investigate the wear of luting materials (Variolink Esthetic LC/DC, Multilink Automix, Panavia V5 paste) compared to a resin composite (Tetric EvoFlow) with an ACTA-machine (three-body-wear simulator) using steel and 3D-printed polymer wheels. Wear was measured (software Match3D) and statistically analyzed (ANOVA). Worn...
Preprint
Objectives: This in vitro study analysed potential of proximal caries detection using 3D range data of teeth consisting of near-infrared reflection images at 850 nm (NIRR). Materials and Methods: 250 healthy and carious permanent human teeth were arranged pairwise, examined with bitewing radiography (BWR) and NIRR and validated with micro-computed...
Article
Full-text available
Objectives The aim of this in vitro study was to evaluate the diagnostic potential of near-infrared reflection at 780 nm (NIRR 780nm ) for early proximal caries detection on the occlusal, buccal and oral surfaces of molars and premolars under simulated, clinically relevant conditions. The findings were validated by micro-computed tomography (µCT)....
Article
Full-text available
Objectives This study evaluated the adhesion and whitening effects of a combination of P11-4 self-assembling peptide and hydroxyapatite (peptide-HAP) on bovine enamel. Methods Forty-six caries-free bovine teeth were selected, and 40 teeth were randomly allocated to one of five groups (n = 8). First, the effects of application frequency, exposure t...
Article
Purpose: The aim of this study was to compare different concepts of direct composite restorations in class II cavities using bulk-fill composites and a conventional composite with different layer thicknesses in a clinical study over a period of 2 years. Materials and Methods: A low-viscosity (SDR), a high-viscosity bulk-fill (Tetric EvoCeram Bulk...
Article
Full-text available
IntroductionThe aim of this study was to experimentally investigate the potential of different light wavelengths to distinguish between healthy and carious tissue using a two-circle goniometer.Materials and methodsTooth slices were prepared from extracted human teeth that were caries free (n = 15) or had occlusal caries lesions (n = 10). The tooth...
Article
Full-text available
Objectives Sufficient depth of cure allows bulk-fill composites to be placed with a 4-mm thickness. This study investigated bulk versus incremental application methods by visualizing shrinkage vectors in flowable bulk-fill and conventional composites.Materials and methodsCylindrical cavities (diameter = 6 mm, depth = 4 mm) were prepared in 24 teeth...
Preprint
Objectives: The aim of this in vitro study was to evaluate the diagnostic potential of near-infrared reflection at 780 nm (NIRR 780nm) for early proximal caries detection on the occlusal, buccal and oral surfaces of molars and premolars under simulated, clinically relevant conditions. The findings were validated by micro-computed tomography (µCT)....
Article
Bulk-fill composites can be placed at a thickness of 4 mm due to their sufficient depth of cure. The aim of this study was to investigate the effects of bulk versus incremental application methods on the shrinkage vectors and the percentage of volumetric polymerization shrinkage of the composites. Twelve molars were divided into three groups (n = 4...
Article
Full-text available
The aim of this study was to assess near-infrared transillumination with high dynamic range imaging (NIRT-HDRI) for occlusal caries detection in vitro and to compare it with visual inspection using the International Caries Detection and Assessment System II (ICDAS) and digital bitewing radiography (BWR). Sixty-one extracted permanent molars with so...
Article
Objectives We aimed to compare the diagnostic accuracy of two intraoral digital X-ray sensors—the charged-coupled device (CCD) and complementary metal-oxide-semiconductor (CMOS)—for proximal caries detection in permanent molar and premolar teeth. Micro-computed tomography served as the reference standard. Methods Two hundred fifty samples were mou...
Article
Full-text available
Objectives The corona disease (COVID-19) is developing into one of the greatest challenges for healthcare professionals around the world. In this article, we report the detailed actions taken in the Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians-University (LMU), Munich, Germany, during the early ph...
Article
Objectives The aim of this study was to evaluate the bonding of an universal adhesive to residual affected dentin after polymer bur excavation of natural caries lesions in human teeth. Materials and methods Caries excavation with a polymer bur and with a carbide bur were compared. A microtensile bond strength (μ-TBS) test was performed in a split-...
Article
Full-text available
Objectives Cryopreservation is discussed as a viable method of preserving teeth for determined autogenous tooth transplantation. Unchanged physical properties of hard tooth tissues are crucial for functional healing. Due to different thermal expansion coefficients of enamel and dentin or the crystallization process, the freezing process may lead to...
Article
Full-text available
The aim of this study was the in‐vitro validation of VistaCam iX HD, which uses near‐infrared reflection (NIRR), for proximal caries detection. It was compared with digital bitewing radiography (BWR), and micro‐computed tomography (µCT) was used as the reference standard. One‐hundred teeth with either sound (n = 54) or carious (n = 46) proximal sur...
Article
Full-text available
Objectives The aim of the present in vitro study was to determine the ability of Diagnocam to detect caries at an early stage and to compare it with digital radiography. Materials and methods One hundred twenty proximal surfaces composed equally of sound and decayed surfaces were evaluated by assessing images captured with Diagnocam (Kavo, Biberac...
Article
Objective: The aim of this study was to investigate the three-body wear of different additively manufactured temporary materials, one temporary PMMA material for CAD/CAM milling and one resin-based composite for direct restorations as a control group by using an ACTA machine. Methods: Specimens (n=8) of the 3D printing materials 3Delta temp, Nex...
Article
Objective: The fracture resistance of different ultrathin occlusal computer-aided design/computer-aided manufacturing (CAD/CAM) veneers was investigated under cyclic mechanical loading to restore combined enamel-dentin defects. Methods: Eighty-four molars were reduced occlusally until extensive dentin exposure occurred with a remaining enamel ri...
Patent
The invention is about a non-oxidizing method to whiten teeth. The working mechanism is increase of diffuse reflection and, to a minor part, fluorescence. Hydroxyapatit- or calcium-phosphate-particles of a certain size are attached to the tooth surface with a matrix protein with a high affinity to calcium.
Article
Full-text available
Objectives Bond strength to enamel and dentin depends on the bonding approach or condition. This study investigated the effects of the boundary conditions, in terms of the bonding substrate and the bonding condition, on the shrinkage vectors of a flowable composite. Materials and methods An experimental cylindrical cavity (diameter = 6 mm, depth =...
Article
Full-text available
Objectives This study aimed to assess the effects of fiber incorporation on the contraction stress (CS), time to gelation (TG), and temperature rise (TR) features of two experimental resin-based composites (RBCs) in comparison to those of bulk-fill RBCs and conventional RBCs in simulated, clinically relevant cavities. Materials and methods CS over...
Article
Immobilization of proteins has been examined to improve implant surfaces. In this study, titanium surfaces were modified with nanofunctionalized denosumab (cDMAB), a human monoclonal anti-RANKL IgG. Noncoding DNA oligonucleotides (ODN) served as linker molecules between titanium and DMAB. Binding and release experiments demonstrated a high binding...
Article
Full-text available
Aim The aim of the present randomized, controlled trial was to compare the impact of the regular use of a fluoride‐free microcrystalline hydroxyapatite (HAP) dentifrice and a 1400 ppm fluoride control dentifrice on caries progression in 150 highly caries‐active orthodontic patients. Methods The primary outcome was the occurrence of lesions with In...
Article
This study evaluated surface gloss, roughness and color change of six current flowable composites after simulated toothbrushing, including four traditional flowable composites (i.e. GrandioSO Flow, Arabesk Flow, Kerr Revolution Formula 2 and Gradia Direct LoFlo), one self-adhering flowable composite (Kerr Vertise Flow) and one universal injectable...
Presentation
Objective: Previously we reported the rapid silica thin film coating method on enamel surface. The purpose of this study was to evaluate the wear resistance, surface roughness and microhardness of the silica thin-film. Methods: 10 % of preceramic polymer perhydropolysilazane (PHPS; AZ Electronic Materials, Tokyo, Japan) solution was used. Polish...
Conference Paper
The ever increasing sizes of 3D micro and nano CT images challenge established image registration approaches that require images to fit into random access memory (RAM). The aim of this work is to overcome this limitation by using modern solid-state disks (SSD) in combination with a novel image encoding scheme and on-the-fly compression thus allowin...
Article
Full-text available
Objective: The objective of this study was to investigate the effects of cavity configuration on the shrinkage vectors of a flowable resin-based composite (RBC) placed in occlusal cavities. Materials and methods: Twenty-seven human molars were divided into three groups (n = 9) according to cavity configuration: "adhesive," "diverging," and "cyli...
Article
Objectives: The aim of this combined in vitro and in vivo study was to evaluate the efficacy of tooth whitening using a mixture of Self- Assembling Peptide Matrix (SAPM) and hydroxyapatite (HA). Methods: The mixture was applied on stained bovine teeth, and the tooth color was measured using a spectrophotometer; mean changes in L*a*b values betwe...
Preprint
Recent evidence for a significant interference of microcrystalline hydroxapatite (HAP) particles with re- and demineralisation processes at the tooth-biofilm interface suggested, that they may be promising candidates for efficacious caries prevention. This multicenter randomized controlled non-inferiority trial evaluated the impact of the 2 x daily...
Article
The purpose was to develop an in vitro model for the validation of near-infrared transillumination (NIRT) for proximal caries detection, to enhance NIRT with high-dynamic-range imaging (HDRI), and to compare both methods, using micro-computed tomography (µCT) as a reference standard. Both proximal surfaces of 53 healthy or decayed permanent human t...
Article
Die Kariesexkavation ist fester Be- standteil der restaurativen Versorgung kariöser Läsionen. Vor dem Hintergrund der Vitalerhaltung der Pulpa wird der Um- gang mit pulpanahen Dentinläsionen seit vielen Jahren kon- trovers diskutiert. Das therapeutische Spektrum umfasst da- bei alle Aspekte vom weitgehenden Erhalt kariös veränderten Dentins bis zum...
Article
Polymerization shrinkage of dental resin composites leads to stress build-up at the tooth-restoration interface that predisposes the restoration to debonding. In contrast to the heterogeneity of enamel and dentin, this study investigated the effect of boundary conditions in artificial cavity models such as ceramic and Teflon. Ceramic serves as a ho...
Article
Purpose: To evaluate the effect of simulated toothbrush abrasion on the surface gloss, the surface roughness and the color stability of incrementally-filled and bulk-fill composites. Methods: 48 dimensionally standardized composite specimens (n= 8/group) were made from four incrementally-filled composites (Tetric EvoCeram, IPS Empress Direct Ena...
Article
Full-text available
This study investigated the color stability and microhardness of five composites exposed to four beverages with different pH values. Composite discs were produced (n=10); Filtek Z250 (3M ESPE) and Filtek P90 (3M ESPE) were applied in two layers (2 mm, 20 seconds), and Tetric N-Ceram Bulk Fill (TetricBF, Ivoclar Vivadent) and SonicFill (Kerr) were a...
Article
Full-text available
Background/purpose: For light-initiated dental hybrid composites, reinforcing particles are much stiffer than the matrix, which makes the surface rugged after inadequate polish and favors bacterial adhesion and biofilm redevelopment. The aim of the study was to investigate the polishing mechanism via the geometric optics approach. Methods: We de...
Article
Purpose: To investigate the in vitro shear bond strength of two adhesives to bovine dentin contaminated with various astringents. Methods: 120 adult bovine incisors were collected and cut to obtain 240 specimens. The specimens were randomly divided into a self-etch adhesive group (N = 120) and a total-etch adhesive group (N = 120). Both of the g...
Conference Paper
In order to systematically develop ultrathin occlusal ve- neers, an experimental fatique simulation has been complemented with a finite element analysis (FEA) based on micro CT images of the very same specimen. Based on free software, a tool chain for preprocessing, FEA and visualisation has been established and successfully applied.
Patent
The invention is about a non-oxidizing method to whiten teeth. The working mechanism is increase of diffuse reflection and, to a minor part, fluorescence. Hydroxyapatit- or calcium-phosphate-particles of a certain size are attached to the tooth surface with a matrix protein with a high affinity to calcium.
Presentation
Objectives: As bonding to enamel is stronger than bonding to dentin, the aim of this study was to determine enamel’s influence as a bonding substrate on the direction of shrinkage vectors.Methods: 36 human teeth were divided into 4 groups (n=9); first, according to the cavity form into experimental (EXP) and cylindrical (CYL) groups, then subdivide...
Presentation
Objectives: Sufficient depth of cure allows bulkfill composites to be placed in 4mm thickness but little is known about its shrinkage vectors. The aim of this study was to investigate shrinkage vectors in the bulkfill restorative material Smart Dentin Replacement (SDR, Dentsply). Methods: 16 teeth were divided into two groups (n=8): SDR-bulk (SB)...
Poster
Objectives: To evaluate how hydroxyapatite (HAP) suspended in a self-assembling peptide matrix contributes to tooth whitening. Methods: In the literature two alternative explanations are offered how HAP contributes to the whitening of teeth: Niwa at al. (2001) suggest that remineralization processes make surfaces of teeth smoother and glossier, w...
Article
Objective: This in vitro study aimed to evaluate occlusal caries extension in relation to visual and radiographic diagnostic criteria and their clinical value to indicate operative or preventive dental care. Methods: A total of 196 third molars with clinically sound occlusal fissures or noncavitated lesions were collected. Before microcomputed t...
Article
Objectives: The aim of this in vitro study was to consecutively determine the effect of three bonding agents on the prevention of enamel demineralisation at the bracket-periphery and to compare the suitability of micro-computed tomography (μCT) scans and quantitative light-induced fluorescence (QLF) to detect changes within subsurface lesions. Ma...
Article
Objectives The aim of this study was to assess the effect of two sealants and two varnishes on the prevention of enamel demineralization, as well as the effect of inattentive surplus enamel-etching by a self-etching primer (SEP). Materials and methods The sealants ProSeal and Clinpro and the varnishes Protecto and FluorProtector were investigate...
Article
The purpose of this study is to investigate the in vitro tribological behavior of modern nonmetallic restorative materials. Specimen prepared of IPS e.max Press lithium disilicate glass ceramic, IPS Empress Esthetic leucite-reinforced glass ceramic, Everest ZS Blanks yttria-stabilized zirconia and Lava Ultimate composite were subjected to wear usin...
Conference Paper
Objective: This study was carried out to evaluate the tensile strength and wear loss of the experimental light-cured composites containing spherical fillers treated with a novel 3-(3-methoxy-4- methacryloyloxyphenyl)propyltrimethoxysilane (p-MBS) which has a phenyl group as a hydrophobic group. Methods: Experimental light-cured composites were fo...
Article
Full-text available
Purpose: To evaluate gloss and surface roughness (Ra-value) of four universal nanohybrid composites and four flowable nanohybrid composites before and after toothbrush abrasion. Methods: 64 dimensionally standardized specimens (n= 8/group) were prepared from four universal nanohybrid composites (i.e. Filtek Supreme XTE Universal, Grandio, Tetric...
Article
Purpose: To evaluate and compare the use of micro-computed tomography (microCT) to investigate the mineral concentration of the treated dentin surface after caries removal with fluorescence-aided caries excavation (FACE) and conventional excavation. Methods: 20 extracted human teeth with dentin caries were bisected through the lesion center into...
Article
The purpose of our study was to evaluate the effects of surface treatment on the microtensile bond strength (MTBS) of silorane-based composites (Filtek Silorane, 3M ESPE) repaired with methacrylate-based composites (Ceram X, Dentsply). The MTBS were measured before or after thermo-mechanical fatigue simulation (FS). The surface conditioning regimes...
Article
The aim of this in-vitro study was to evaluate the efficacy of tooth whitening using different calcium phosphate-based formulations. Teeth were treated with three different hydroxyapatite preparations at different concentrations and with two control preparations; each tooth was treated a total of three times. After application of the last material,...
Conference Paper
Glass ionomer cements (GIC) are widely used in dental practice . However, GIC tend to fracture due to their inherent brittleness which is influenced by porosity. The aim of the image processing methods presented in this contribution is to automatically visualise and quantify GIC porosity from volumetric micro CT images. The final aim is to relate p...
Article
Objective: The aim of this in vitro study was to compare fluorescence-aided caries excavation with conventional excavation based on the Martens and Vickers hardness of dentin at the cavity floor after caries removal. Materials and methods: In total, 20 extracted human teeth with dentin caries were bisected through the lesion center into two halv...
Article
Intentional cranial deformations (ICD) have been observed worldwide but are especially prevalent in preColombian cultures. The purpose of this study was to assess the consequences of ICD on three cranial cavities (intracranial cavity, orbits, and maxillary sinuses) and on cranial vault thickness, in order to screen for morphological changes due to...
Poster
Objectives : The objectives of this study were to evaluate the gloss and the surface roughness (Ra) of four nanohybrid composites and four flowable nanohybrid composites before and after toothbrush simulation. Methods : Sixty-four dimensionally standardized specimens (n=8/group) were prepared from four nanohybrid composites (i.e., Tetric EvoCeram...
Presentation
Objective: To visualize polymerization shrinkage of a light-initiated resin-composite in form of displacement vector fields (DVF) and to detect the effect of different cavity-configurations on shrinkage direction in relation to light-source. Method: 27 human teeth were divided into three groups (n=9) according to cavity-configuration into adhesi...
Presentation
Objective: The application of an adhesive monomer to the surface of glassionomer cements (GIC) is recommended to improve their mechanical properties. The purpose of this study was to investigate the efficiency of two different light-cured nanofilled coating materials with regard to the wear of GIC. Method: Tested materials were: GC Equia (EQ, GC Co...