Karine MarcotteUniversité de Montréal | UdeM · School of Speech Pathology and Audiology
Karine Marcotte
Ph.D. Biomedical sciences, speech language pathology option
About
91
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Introduction
Karine Marcotte currently works at the School of Speech Pathology and Audiology, Université de Montréal. Karine does research in Neuroplasticity in post-stroke aphasia as well as in primary progressive aphasia. I am also working on a project on the efficacy of a new mirror effect protocol in acute Bell's palsy.
Skills and Expertise
Publications
Publications (91)
BACKGROUND
Poststroke aphasia (PSA) recovery shows high variability across individuals and at different time points. Although diffusion biomarkers from the ventral and dorsal streams have demonstrated strong predictive power for language outcomes, it is still unclear how these biomarkers relate to the various stages of PSA recovery. In this study,...
Background
Recently, our research team developed an open source and free website called the MEPP website (for the Mirror Effect Plus Protocol) to efficiently provide mirror therapy for patients with facial palsy. Previous studies demonstrated that the first version of the MEPP website improved user experience and likely optimized patients’ performa...
Background
Over 50% of individuals with aphasia face ongoing word‐finding issues. Studies have found phonologically oriented therapy helpful for English speakers, but this has not yet been studied in French. It is essential to assess the effectiveness of such a therapy in French, considering the distinct linguistic typologies between both languages...
Background: Recently, our research team developed an open source and free website called the MEPP website (for the Mirror Effect Plus Protocol) to efficiently provide mirror therapy for patients with facial palsy. Previous studies demonstrated that the first version of the MEPP website improved user experience and likely optimized patients’ perform...
Objective: Limited normative data (including psychometric properties) are currently available on discourse tasks in non-dominant languages such as Laurentian (Quebec) French. The lack of linguistic and cultural adaptation has been identified as a barrier to discourse assessment. The main aim of this study is to document inter-rater and test-retest...
Background: Post-stroke aphasia (PSA) recovery shows high variability across individuals and at different moments during recovery. Although diffusion biomarkers from the ventral and dorsal streams have demonstrated strong predictive power for language outcomes, it is still unclear how these biomarkers relate to the various stages of PSA recovery. I...
Purpose: Early impairments in spoken discourse abilities have been identified in Alzheimer’s disease (AD). However, the impact of AD on spoken discourse and the associated neuroanatomical correlates have mainly been studied in populations with higher levels of education, although preliminary evidence seems to indicate that socioeconomic status (SES...
White matter (WM) is often severely affected after human ischemic stroke. While animal studies have suggested that various factors may contribute to WM structural damage after ischemic stroke, the characterization of damaging processes to the affected hemisphere after human stroke remains poorly understood. Thus, the present study aims to thoroughl...
Purpose
Main concept (MC) analysis is a well-documented method of discourse analysis in adults with and without brain injury. This study aims to develop a MC checklist that is culturally and linguistically adapted for Canadian French speakers and examine its reliability. We also documented microstructural properties and provide a normative referenc...
Contexte : Le programme de maîtrise professionnelle en orthophonie de l’Université de Montréal a connu une refonte complète de programme en 2020, et s’inscrit maintenant dans une approche par compétence. La formation par concordance de script (FpC) a été intégrée au programme de formation afin de contextualiser plus rapidement les apprentissages et...
Background:
Discourse analysis has recently received much attention in the aphasia literature. Even if post-stroke language recovery occurs throughout the longitudinal continuum of recovery, very few studies have documented discourse changes from the hyperacute to the chronic phases of recovery.
Aims:
To document a multilevel analysis of discour...
Background: Little is known about story retelling and comprehension abilities in groups with lower levels of education and socioeconomic status (SES). A growing body of evidence suggests the role of an extended network supporting narrative comprehension, but few studies have been conducted in clinical populations, even less in developing countries....
Purpose
During the COVID-19 pandemic, clinicians and researchers have increasingly used remote online assessments to pursue their activities, but mostly with tests not validated for videoconference administration. This study aims to validate the remote online administration of picture description in Canadian French neurotypical speakers and to expl...
The general objective of these reviews will be to assess the psychometric properties of the measures used for the assessment of rehabilitation technologies and related services. This general objective will answer following question: What is the quality of measures that were used to assess the usability (effectiveness, efficiency, satisfaction) of r...
Diffusion imaging (DWI) is considered an optimal technique to detect hyperacute cerebral ischemia and has thus enriched the clinical management of patients with suspected stroke. Researchers have taken this technique beyond with Diffusion Tensor Imaging (DTI)-extracted measures, which have been proposed as biomarkers of stroke progression. A large...
Objective
To study the effects of the “Mirror Effect Plus Protocol” (MEPP) on global facial function in acute and severe Bell's Palsy.
Design
Single blind and randomized controlled trial to compare the effects of basic counseling (control group) versus MEPP (experimental group) over one year.
Setting
Outpatient clinic following referrals from Eme...
Objective
Individuals with a stroke in either the left hemisphere (LH) or the right hemisphere (RH) often present macrostructural impairments in narrative abilities. Understanding the potential influence of low education and low socioeconomic status (SES) is critical to a more effective assessment of poststroke language. The first aim was to invest...
White matter hyperintensities (WMHs) are frequently observed on structural neuroimaging of elderly populations and are associated with cognitive decline and increased risk of dementia. Many existing WMH segmentation algorithms produce suboptimal results in populations with vascular lesions or brain atrophy, or require parameter tuning and are compu...
Purpose
An open source and free website called Mirror Effect Plus Protocol (MEPP)-website was developed with features to diminish cognitive load and support motor learning during facial exercises. Assessing patient’s perceptions is crucial when developing rehabilitation tools because patients’ willingness to use the tools strongly affect engagement...
Purpose: An open source and free website called Mirror Effect Plus Protocol (MEPP)-website was developed with features to diminish cognitive load and support motor learning during facial exercises. Assessing patient's perceptions is crucial when developing rehabilitation tools because patients' willingness to use the tools strongly affect engagemen...
This article has been accepted for publication in the American Journal of Speech-Language Pathology (August 12th 2021)
Abstract
The main aim of the current study is to provide French-Canadian reference data for quantitative measures extracted from connected speech samples elicited by the Western Aphasia Battery-Revised (WAB-R) Picnic scene, a disc...
Theatre has come to be one of the main artistic ways to convey the voices of people with disability to the general audience, and this includes people with language and communication disorders. This article aims to describe and discuss the activities of Le Théâtre Aphasique, a non-profit organization located in several cities in Quebec that delivers...
Genesis of development of our web tool MEPP website 2.0
White matter hyperintensities (WMH) are frequently observed on structural neuroimaging of elderly populations and are associated with cognitive decline and increased risk of dementia. Many existing WMH segmentation algorithms produce suboptimal results in populations with vascular lesions or brain atrophy, or require parameter tuning and are comput...
Background
Previous findings have demonstrated the importance of discourse analysis in post-stroke aphasia, as it allows for in-depth examination of language impairment and represents key components of functional communication. However, little is known about the recovery of discourse over time.
Aims
The main aim of this study is to measure the lon...
Long term effects of MEPP on Bell's Palsy
Results of our longitudinal study about MEPP on BP patients
Background
A growing body of literature has demonstrated the importance of discourse assessment in patients who suffered from brain injury, both in the left and right hemispheres, as discourse represents a key component of functional communication. However, little is known about the relationship between gray matter density and macrolinguistic proce...
A growing body of literature has demonstrated the importance of discourse assessment in patients who suffered from brain injury, both in the left and in the right hemisphere, as discourse represents a key component of functional communication. However, little is known about the relationship between grey matter density and macrolinguistic processing...
The purpose of this study was to examine the impact of age and education on the neural and behavioral correlates of verbal fluency. Forty-eight healthy adult participants were included: high-educated young and elderly, low-educated young and elderly. Participants performed semantic and phonemic and a control task during fMRI scanning. The phonemic...
Background
Small but interesting evidences suggest that facial rehabilitation for acute Bell Palsy (BP) could improve facial outcomes in patients who benefited from optimal medication, but whose symptoms are still severe two weeks after BP’s onset.
Aims
This study aimed to provide preliminary evidence of the long-term effects of a new facial retra...
A longitudinal study of narrative discourse in post-stroke aphasia
Synkinesis is a distressing sequela of peripheral facial palsy (PFP). Thisstudy aimed to translate and validate the Synkinesis Assessment Questionnaire (SAQ), a reliable patient-reported outcome evaluation tool for synkinesis, in French. The SAQ was translated following a standard forward-backward translation procedure. After a cognitive debriefing...
Objective:
The present study aims to assess the relationship between quantitative measures of connected speech production and performance in confrontation naming in early post-stroke aphasia (8-14 days post-stroke). Method: We collected connected speech samples elicited by a picture description task and administered a confrontation naming task to...
Sleep spindles are an essential part of non-rapid eye movement sleep, notably involved in sleep consolidation, cognition, learning, and memory. These oscillatory waves depend on an interaction loop between the thalamus and the cortex, which relies on a structural backbone of thalamo-cortical white matter tracts. It is still largely unknown if the b...
Introduction: Bell’s palsy has significant physical, functional and social consequences. Our team has recently developed the Mirror Effect Plus Protocol (MEPP) which seems to demonstrate promising effects in reducing the symptoms of acute Bell's palsy. To date, most studies on Bell's palsy only assess physical symptoms and do not report the impact...
Intro: Les effets psychologiques et fonctionnels de la paralysie de Bell sont dévastateurs. Or, peu de données existent sur l'efficacité des interventions en phase aiguë de Paralysie de Bell. Il existe même une certaine résistance des milieux cliniques à offrir de la rééducation précoce, vu la difficulté à distinguer les effets de la réadaptation d...
Background: The greatest degree of language recovery in post-stroke aphasia takes place within the first weeks. Aphasia severity and lesion measures have been shown to be good predictors of long-term outcomes. However, little is known about their implications in early spontaneous recovery. The present study sought to determine which factors better...
Combining early facial exercises with medication may help patients with acute Bell's palsy recover significantly faster and better than patients treated with medication alone. To date, exercise therapy in acute Bell's palsy consists mostly of transferring facial rehabilitation techniques that were developed for chronic Bell's palsy, despite the dif...
Considération de la perception des patients à propos de leurs difficultés fonctionnelles et sociales pendant la thérapie MEPP
Background: Discourse analysis allows the examination of functional and ecological language impairment in post-stroke aphasia. Given its complexity, various methods of analysis have been developed to measure the multiple components of discourse. Clinical assessment usually includes discourse analysis, but how clinicians should assess recovery of di...
Background: The greatest degree of language recovery in post-stroke aphasia takes place within the first weeks. Aphasia severity and lesion measures have been shown to be good predictors of long-term outcomes. However, little is known about their implications in early spontaneous recovery. The present study sought to determine which factors better...
Narrative discourse recovery in the acute stage of post-stroke aphasia
The restorative function of sleep partly relies on its ability to deeply synchronize cerebral networks to create large slow oscillations observable with EEG. However, whether a brain can properly synchronize and produce a restorative sleep when it undergoes massive and widespread white matter damage is unknown. Here, we answer this question by test...
High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments. However, test-retest reliability measurements are essential to ascertain that the longitudinal va...
Despite the growing evidence regarding the importance of intensity and dose in aphasia therapy, few well-controlled studies contrasting the effects of intensive and non-intensive treatment have been conducted to date. Phonological components analysis (PCA) treatment for anomia has been associated with improvements in some patients with chronic apha...
Accuracy of production of treated and untreated words as a function of treatment condition.
La paralysie de Bell (PB) entraine une perte subite de la fonction musculaire du visage. La récupération est incomplète voire absente pour 30% des patients. Des changements neuroanatomiques significatifs, notamment dans les aires d'intégration sensorimotrices, sont observées dès les premiers jours suivant la PB, et suggèrent que les modifications c...
Lengthening temporalis myoplasty is a surgical procedure to restore the smile in patients with irreversible facial nerve paralysis. The temporalis muscle is detached from its upper end and attached to the labial commissure. Following surgery, facial rehabilitation by speech-language pathologists is necessary to achieve a functional smile. More spec...
Purpose:
The Functional Assessment of Verbal Reasoning and Executive Strategies (FAVRES; MacDonald, 2005) test was designed for use by speech-language pathologists to assess verbal reasoning, complex comprehension, discourse, and executive skills during performance on a set of challenging and ecologically valid functional tasks. A recent French ve...
Differential patterns of white matter disruption have recently been reported in the non-fluent (nfvPPA) and semantic (svPPA) variants of primary progressive aphasia (PPA). No single measure is sufficient to distinguish between the PPA variants, but connected speech allows for the quantification of multiple measures. The aim of the present study was...
Effets de la rééducation du sourire post myoplastie d'allongement du temporal
Anomia, or impaired word retrieval, is the most widespread symptom of aphasia, an acquired language impairment secondary to brain damage. In the last decades, functional neuroimaging techniques have enabled studying the neural basis underlying anomia and its recovery. The present study aimed to explore maladaptive plasticity in persistent verb anom...
Differential patterns of impairment with respect to noun and verb production have been observed in the nonfluent and semantic variants of primary progressive aphasia. However, the factors influencing this discrepancy remain unclear. The present study evaluates verb retrieval in primary progressive aphasia using a naming task and a story completion...
This study aimed at investigating the neural basis of word learning as a function of age and word type. Ten young and ten elderly French-speaking participants were trained by means of a computerized Spanish word program. Both age groups reached a similar naming accuracy, but the elderly required significantly more time. Despite equivalent performan...
Previous research on participants with aphasia has mainly been based on standard functional neuroimaging analysis. Recent studies have shown that functional connectivity analysis can detect compensatory activity, not revealed by standard analysis. Little is known, however, about the default-mode network in aphasia. In the current study, we studied...
The study of the neural basis of syntactic processing has greatly benefited from neuroimaging techniques. Research on syntactic processing in bilinguals has used a variety of techniques, including mainly functional magnetic resonance imaging (fMRI) and event-related potentials (ERP). This paper reports on a functional near-infrared spectroscopy (fN...
Relatively few studies have analyzed the mechanisms underlying the cognitive changes that affect language in the elderly, and fewer have done so for narrative discourse. The goal of this study was to explore the neurofunctional changes associated with aging for different components of narrative discourse. Functional near-infrared spectroscopy (fNIR...
Bilinguals must focus their attention to control competing languages. In bilingual aphasia, damage to the fronto-subcortical loop may lead to pathological language switching and mixing and the attrition of the more automatic language (usually L1). We present the case of JZ, a bilingual Basque-Spanish 53-year-old man who, after haematoma in the left...
This event-related functional magnetic resonance imaging (fMRI) study reports on the impact of semantic feature analysis (SFA) therapy on the neural substrate sustaining the recovery from severe anomia in two patients: one participant was diagnosed with primary progressive aphasia (PPA) 2 years before this study; the other participant acquired apha...
This study investigated the neural correlates of second-language lexical acquisition in terms of learning phase and word type. Ten French-speaking participants learned 80 Spanish words-40 cognates, 40 non-cognates-by means of a computer program. The learning process included the early learning phase, which comprised 5 days, and the consolidation ph...