Karen Keane

Karen Keane
Galway-Mayo Institute of Technology | GMIT

BSc (Hons), MRes, PhD

About

47
Publications
9,371
Reads
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591
Citations
Citations since 2016
38 Research Items
588 Citations
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
Additional affiliations
February 2016 - present
Northumbria University
Position
  • Lecturer
Education
October 2013 - May 2017
October 2012 - September 2013
Robert Gordon University
Field of study
  • The effect of Selenium Supplementation and/or HIIT on antioxidant status and oxidative stress in active females.
September 2008 - June 2012
University of Limerick
Field of study
  • Sport and Exercise Sciences

Publications

Publications (47)
Article
Full-text available
To investigate the phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of selected phenolic acids on vascular smooth muscle cells in vitro. In a randomised, double-blinded, crossover design, 12 healthy males consumed either 30 or 60 mL of Montmorency tart cherry concentrate. Following analys...
Article
Cerebral blood volume and metabolism of oxygen decline as part of human ageing, and this has been previously shown to be related to cognitive decline. There is some evidence to suggest that polyphenol-rich foods can play an important role in delaying the onset or halting the progression of age-related health disorders such as CVD and Alzheimer’s di...
Article
Full-text available
Background: Tart cherries contain numerous polyphenolic compounds that could potentially improve endothelial function and reduce cardiovascular disease risk. Objective: We sought to examine the acute effects of Montmorency tart cherry (MC) juice on vascular function in subjects with early hypertension. Design: A placebo-controlled, blinded, cr...
Article
This study examined whether beetroot juice (BTJ) would attenuate inflammation and muscle damage following a marathon. Using a double blind, independent group design, 34 runners (each having completed ca. ∼16 previous marathons) consumed either BTJ or an isocaloric placebo (PLA) for 3 days following a marathon. Maximal isometric voluntary contractio...
Article
Aim: To determine if neuromuscular disturbances are modulated following a repeated bout of eccentric exercise METHODS: Following eccentric exercise performed with the elbow-flexors, we measured maximal voluntary force, resting twitch force, muscle soreness, creatine kinase and voluntary activation using motor point and motor cortex stimulation at...
Article
Full-text available
Background Sports science research in elite female Gaelic team sports has increased in recent years, but still a large disparity exists between the volume of studies involving male and female players. As a consequence of this, it is difficult for practitioners to develop an evidence-based approach when working with female players. Main body In thi...
Article
Full-text available
Background Circulating biomarkers are often used to investigate the bone response to an acute bout of exercise, but heterogeneity in factors such as study design, quality, selected biomarkers, and exercise and participant characteristics render it difficult to synthesize and evaluate available evidence. Objective The aim of this study was to quant...
Preprint
Full-text available
Circulating biomarkers are used to investigate the bone response to an acute bout of exercise, but heterogeneity in factors such as study design, quality, selected biomarkers and exercise and participant characteristics render it difficult to synthesize and evaluate available evidence. PURPOSE: To quantify the effects of an acute exercise bout on b...
Article
Full-text available
Background: Food high in (poly)phenolic compounds, such as anthocyanins, have the potential to improve exercise recovery and exercise performance. Haskap berries are rich in anthocyanins, but no research has examined the potential to improve human performance. The aim of this study was to determine the influence of Haskap berry on parameters of en...
Article
Full-text available
Tart Montmorency cherries (MC) are a particularly rich source of anthocyanins and other polyphenols that have been shown to elicit antioxidant, anti-inflammatory and vasomodulatory actions. This study aimed to determine the influence of chronic MC supplementation on cognitive function and mood. In a 3-month double-blinded, placebo-controlled parall...
Article
Full-text available
Background Red beetroot ( Beta vulgaris L. ) is a multifunctional functional food that reportedly exhibits potent anti-inflammatory, antioxidant, vasodilation, and cellular regulatory properties. This vegetable has gained a fair amount of scientific attention as a possible cost-effective supplement to enhance performance and expedite recovery after...
Article
Full-text available
Although physical activity is a health-promoting, popular global pastime, regular engagement in strenuous exercises, such as long-distance endurance running races, has been associated with a variety of detrimental physiological and immunological health effects. The resulting altered physiological state has previously been associated with fluctuatio...
Article
Full-text available
Montmorency tart cherries (MC) have been found to modulate indices of vascular function with interventions of varying duration. The objective of this preliminary study was to identify the chronic effects of MC supplementation on vascular function and the potential for urinary metabolomics to provide mechanistic evidence. We performed a placebo-cont...
Article
New Zealand blackcurrant (NZBC) extract is a rich source of anthocyanins and in order to exert physiological effects, the anthocyanin-derived metabolites need to be bioavailable in vivo. We examined the plasma uptake of selected phenolic acids following NZBC extract supplementation alongside maintaining a habitual diet (i.e. not restricting habitua...
Article
Full-text available
Background: Tart Montmorency cherries (MC) have been shown to be rich in anthocyanins and other phytochemicals known to have anti-inflammatory properties and influence pathways that might improve cardiometabolic health. However, there is limited evidence for the longer-term use of tart cherries on these indices. The aim of the current study was to...
Article
Full-text available
Runners commonly utilise cryotherapy as part of their recovery strategy. Cryotherapy has been ineffective in mitigating signs and symptoms of muscle damage following marathon running and is limited by its duration of application. Phase change material (PCM) packs can prolong the duration of cooling. This study aimed to test the efficacy of prolongi...
Article
Full-text available
Background Bone is a plastic tissue that is responsive to its physical environment. As a result, exercise interventions represent a potential means to influence the bone. However, little is currently known about how various exercise and participant characteristics interact to influence bone metabolism. Acute, controlled, interventions provide an in...
Article
The aim of this study was to investigate if videos created by teaching staff had a positive impact on student learning of integrative physiological concepts. Eighteen undergraduate students enrolled on a sport and exercise science degree attended an introduction to immunology short course. All students were taught together and then split into two g...
Article
Full-text available
Endurance athlete performance is greatly dependent on sufficient post-race system recovery, as endurance races have substantial physiological, immunological and metabolic effects on these athletes. To date, the effects of numerous recovery modalities have been investigated, however, very limited literature exists pertaining to metabolic recovery of...
Article
The aim of this study was to determine the efficacy of tart cherry (TC) supplementation on recovery following strenuous exercise. A systematic review and meta-analysis were conducted using studies investigating TC supplementation on measures of muscle soreness, muscular strength, muscular power, creatine kinase, C-reactive protein, Interleukin-6, a...
Presentation
The effect of consuming red and orange cherry tomatoes on blood-borne circulating biomarkers in free-living normotensive males: a randomised cross-over trial - Volume 78 Issue OCE2 - H. M. Cheng, G. Koutsidis, J.K. Lodge, K. Keane, M. Siervo, J. Lara
Article
There is a dearth of information regarding the reliability of non-invasive measures of vascular function taken in a single testing session. This study aimed to determine the test-retest reliability of a test battery of vascular function measures: automated blood pressure (BP), laser Doppler imaging with iontophoresis (LDI), digital volume pulse (DV...
Article
Full-text available
Introduction Endurance races have been associated with a substantial amount of adverse effects which could lead to chronic disease and long-term performance impairment. However, little is known about the holistic metabolic changes occurring within the serum metabolome of athletes after the completion of a marathon. Objectives Considering this, the...
Article
The purpose of this study was to compare anthropometric and lower body power measurements between current professional and amateur male rugby union players. The present study also sought to determine which anthropometric and physical performance variables were predictive of playing standard. Thirty professional and 30 amateur RU players performed W...
Presentation
The effect of consuming red and yellow cherry tomatoes on endothelial function in free-living normotensive males: a randomised cross-over trial - Volume 77 Issue OCE4 - H.M. Cheng, G. Koutsidis, J.K. Lodge, K. Keane, M. Siervo, J. Lara
Article
Accumulating evidence suggests flavonoid intake is associated with reduced risk of non-communicable diseases. We aimed to systematically determine and quantify the potential association between dietary anthocyanin intake and risk of cardiovascular diseases (CVD). A systematic literature search of studies reporting anthocyanin intake and risk of fat...
Article
Full-text available
The purpose of this study was to investigate the effects of Montmorency tart cherry juice (MC) on nitric oxide (NO) biomarkers, vascular function and exercise performance. In a randomized, double blind, placebo (PLA) – controlled, crossover study, 10 trained cyclists (mean ± SD; V̇O2peak 59.0 ± 7.0 ml/kg/min) acutely ingested 30 mL of either MC or...
Article
Full-text available
The purpose of this study was to examine student use and perceptions of technology enhanced learning tools (TELTs), including their value for learning. Students enrolled onto a 12-week undergraduate science module had access to four TELTs each week, (i) a recording of the lecture (Panopto™), (ii) an animated mini review of the lecture (ShowMe), (ii...
Article
Full-text available
Purpose: To evaluate the plasma bioavailability of betanin and nitric oxide (NOx) after consuming beetroot juice (BTJ) and whole beetroot (BF). BTJ and BF were also analysed for antioxidant capacity, polyphenol content (TPC) and betalain content. Methods: Ten healthy males consumed either 250 ml of BTJ, 300 g of BF or a placebo drink, in a rando...
Article
Maximal eccentric contractions induce an immediate strength loss that results from skeletal muscle damage, the symptoms of which can persist for several days after the exercise insult. The repeated bout effect (RBE) refers to the acute adaptive response precipitated from a single bout of eccentric contractions that result in an attenuated damage re...
Article
The repeated bout effect (RBE) refers to the prophylactic effect from damaging exercise following a single prior bout of exercise. There is a paucity of data examining the RBE in females, and investigations employing exercise paradigms beyond isolated eccentric contractions are scarce. In light of the limited literature, this investigation aimed to...
Article
Full-text available
There is a paucity of studies investigating exercise-induced muscle damage (EIMD) in females and only one in response to dance-type exercise. This study sought to firstly elucidate the physiological profile of EIMD following a dance-specific protocol, and second to compare the magnitude of damage to that experienced following a sport-specific proto...
Article
Exercise induced muscle damage (EIMD) is a well-investigated area, however there is a paucity of data surrounding the damage response in females. The aim of this study was to examine the damage responses from a sport-specific bout of repeated sprints in female athletes. Eleven well-trained females (mean ± SD; age 22 ± 3 y, height 166.6 ± 5.7 cm, ma...
Conference Paper
Full-text available
Background: Research examining the repeated bout effect (RBE) following muscle-damaging exercise is well established; however there is a paucity of any data directly examining this phenomenon in females. Similarly investigations employing exercise paradigms beyond isolated eccentric contractions using isokinetic dynamometry are scarce. The external...

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Projects

Project (1)
Project
1. Investigate the altered human serum metabolome induced by a marathon. 2. Elucidate the natural metabolic recovery trend of athletes after a marathon. 3. Determine the effects of beetroot juice supplementation on the altered serum metabolome after a marathon.