Kamelia Mirdamadi

• Doctor of Philosophy
• PhD Student at University of Toronto

Activated T helper 17 (Th-17) cytokines play a role in the pathophysiology of autoimmune and infectious diseases. While these diseases affect many women of childbearing age, little is known about the effect of these cytokines on placental transporters. As several pro-inflammatory cytokines impact the expression of ABC and SLC placental transporters...

ackground: Sleep disturbances during pregnancy are associated with higher risks of maternal depression, hypertension, gestational diabetes and preterm labor. Nocturnal plasma melatonin levels are known to increase as pregnancy proceeds, reaching their peak near term. While insomnia is frequently seen in pregnancy, the possible role of maternal mela...

Background Autoimmune arthritic diseases affect many women of child-bearing age. Tumour necrosis factor (TNF)-α inhibitors are currently used for the treatment of various immune-mediated diseases during pregnancy. However, there has been no evaluation of safety in the treatment of arthritic diseases during gestation. Objective To analyze the risk o...

Insomnia in pregnancy is associated with depression, preeclampsia, gestational diabetes, and preterm labor. In normal pregnancies, maternal plasma melatonin levels increase significantly as pregnancy proceeds, reaching its peak near term. However, the role of melatonin in insomnia during pregnancy is not known. The objective of this study was to me...

Mental health disorders such as schizophrenia and bipolar disorder are common among the women of child bearing age. Obstetric complications and infant outcome of untreated psychiatric illnesses have been studied. Meanwhile there is limited information on the safety of psychotropic medications in pregnancy. Studies demonstrated that treatment with c...

Question: I have been encouraging pregnant women to receive both the H1N1 and influenza vaccines since I became aware of Health Canada's guidelines. However, some of the women in my practice have heard conflicting information, often from media sources, and they are hesitant to be vaccinated. What is the evidence behind these guidelines, and should...

During the H1N1 influenza pandemic in 2009, The Motherisk Program, a counselling service providing teratology information, received many calls from pregnant women inquiring about the safety of the H1N1 vaccine. We wished to explore pregnant women's perception of risk and the factors associated with deciding whether or not to receive the vaccine. Pr...