Kalpana Patil

KLE College of Pharmacy | KLEU · Department of Pharmacognosy

On October 20 to 22, 1994, an interim annual meeting was hosted by the American Society of Pharmacognosy in San Jose, Costa Rica. During the symposium, subject experts from all over the nation shared their insights on issues adjoining intellectual property rights in kith and kin of drug development from naturally derived compounds, plant conservati...

The present is to evaluate the pharmacognostic character of Muntingia Calabura and estimation of quercetin in flavonoid rich leaves and fruit fractions. Pharmacognostic studies were carried out in terms of morphological, microscopic characters, physicochemical parameters and HPLC fingerprint analysis of leaf and fruit extracts of Muntingia calabura...

Background Oxalis corniculata is a well-known medicinal plant used in folk medicine for the management of many diseases. The aim is to determine the physico-chemical properties, microscopic study, phytochemical properties, in-silico, in-vitro antioxidant and anticancer activity on human Hepatocarcinoma (Hep-G2) cell line of O. corniculata plant ext...

Ayurveda is one of the oldest holistic traditional systems of medicine. Tridax procumbens known as “Jayanti Veda” which is weed found throughout India. It shows number of pharmacological activities like Hepatoprotective, Anti-inflammatory, Wound healing, Antioxidant, Antimicrobial, Antidiabetic. The present study was carried out to evaluate antioxi...

In ayurveda Ipomoea cairica has its own importance to treat various health problems. It is tropical plant and a wild relative of sweet potato (Ipomoea batatas), which is considered as one of China's most invasive alien species. Ipomoea cairica is a climber plant in the Convolvulaceae family that is frequently used as a medicinal herb in India and W...

Pharmacognosy deals with the natural drugs obtained from organisms such as most plants, microbes, and animals. It gives immense pleasure to introduce “Text book of Pharmacognosy”, this book contains the detail about various crude drugs obtained from nature along with multiple choice questions, short and long answer question and sample question pape...

Herbal drugs are increasing overall noticeable quality because of their particular points of interest. Creating nations have begun investigating the ethnopharmacological methodology of medication disclosure and have started to document patents on herbal medicines. Worldwide, herbal drug manufacturing units are congregating to these bazaars in an en...

Herbal drugs are increasing overall noticeable quality because of their particular points of interest. Creating nations have begun investigating the ethnopharmacological methodology of medication disclosure and have started to document patents on herbal medicines. Worldwide, herbal drug manufacturing units are congregating to these bazaars in an en...

To study the morpho-anatomy of the aerial parts of Trichosanthes lobata (Cucurbitaceae) to increase the knowledge and standardization parameters of these plants. Morpho-anatomical studies of leaves have been carried out by free hand. The different types of histochemical test were performed by using staining reagents. Phytochemical and quantitative...

Objective: To study the pharmacognostic characters and phytochemical investigation of medicinally important crude drug, Uvaria narum (Dunal) Wall. Ex Wight (Annonaceae) Methods: Organoleptic characters, microscopic evaluation, leaf constants, quantitative physico-chemical evaluations (Ash value, extractive value, moisture content), preliminary phyt...

The aim of the present work is to investigate the possible therapeutic potential of Trichosanthes lobata in paracetamol induced hepatic damage in rats. The hepatotoxicity was induced in rats by administration of paracetamol at higher dose (2 gm/kg) reflected in term of increase lipid peroxidation, impairment in antioxidants [Superoxide Dismutase (S...

Present study was carried out to document plant-based preparations used as abortifacient in three district of North Maharashtra. Data were collected by interviewing local traditional medicinemen, tribals as well as rural people of different villages. A total of twenty claims were obtained. Information on local names, plant parts and different forms...

Objective To study the Hepatoprotective activity of ethanol, chloroform and aqueous extracts of Mentha arvensis leaves against CCL4 induced liver damage in rats.Methods Hepatotoxicity was induced by CCL4 and the biochemical parameters such as serum glutamate pyruvate transminase (sGPT), serum glutamate oxaloacetate transaminase (sGOT), alkaline pho...

Whole plant powder of Kalmegh (Andrographis paniculata) was exposed to gamma irradiation at doses of 5 and 10 kGy in a Co 60 irradiator. Irradiated and unirradiated samples were stored at room temperature. Microbial load of whole plant powder were evaluated at 0, 6 and 12 months of storage. Results indicated that gamma irradiation reduced the total...

In India, a number of medicinal plants and their formulations are used to cure hepatic disorders in traditional systems of medicine. No systemic study has been done on protective effect of Cucumis trigonus Roxb. (Cucurbitaceae) to treat hepatic diseases. Protective action of C. trigonus fruit extracts was evaluated in this study in animal model of...

The study was intended to evaluate the anti-inflammatory activity of non-irradiated and gamma-irradiated (dose 5KGy and 10KGy) samples of Andrographis paniculata in carageenan induced rat paw oedema in Wistar rats at a dose level of 200mg / kg body weight administered orally. Significant anti-inflammatory activity was observed in aqueous extracts o...

The effect of gamma irradiation on pharmacological activity of non-irradiated and gamma-irradiated (at doses of 5 KGy and 10 KGy) samples of Ashwagandha were examined. Investigations were performed to study the anti-stress activity by forced swim endurance test in Albino Swiss mice at a dose level of 100mg / kg b.w. administered orally. Significant...

Aqueous extract of roots of Baliospermum montanum was evaluated on preliminary basis for immunomodulatory activity by studying neutrophil phagocytic function. The different concentration of (25, 50, 100 mug/ml) of aqueous extract of roots of Baliospermum montanum was subjected to study its effect on different in vitro methods of phagocytosis such a...

In the present study aqueous and alcohol extracts of leaves of Melia azedarach Linn. (Meliaceae) were screened for antiulcer activity in aspirin induced and pylorus – ligated rats. The effect was assessed by parameters like pH, free acidity, total acidity and ulcer index. Aqueous extract and alcohol extract of M. azedarach leaves (250 mg/kg b.w., p...

Petroleum ether, chloroform, alcoholic and aqueous extracts of leaves of Gossypium arboreum were screened for anti-ulcer activity in Aspirin induced and Pylorus legated rats. The effect was assessed by parameters like pH, free acidity, total acidity, ulcer index. Oral administration of the extracts chloroform, alcoholic, aqueous at 500 mg/kg proved...

The objective of the present investigation was to study hepatoprotective activity of alcohol, chloroform and aqueous extract of roots of Baliospermum montanum paracetamol induced liver damage model in rats. Liver damage in rats was produced by paracetamol (2 g/kg, po) in tween 80. Alcohol, chloroform, aqueous extracts of roots of the plant was admi...

Objective: To study the effect of aqueous extract of leaves of Enhydra fluctuans on neutrophil phagocytic function. Methods: The different concentrations of (25,50, 100μg/ml) of extract of leaves of Enhydra fluctuans was subjected to study its effect on different in-vitro methods of phagocytosis such as neutrophil locomotion, chemotaxis, immunostim...

Objective: To study the anti-arthritic activity of leaves of Calotropis gigantea. Materials and methods: Petroleum ether (40-60°), ethyl acetate, ethanol and aqueous extract of Calotropis gigantea leaves were tested for various preliminary phytoconstituents and were screened for anti-arthritic activities using Freund's adjuvant arthritis in albino...

Objective: To study the effect of methanol extract of Ipomoea batatas root on neutrophils phagocytic function. Methods: Different concentrations (10, 20,50,100,1000 μg/ml) of methanol extract of Ipomoea batatas root was subjected to study its effect on different in vitro methods of phagocytosis such as neutrophils locomotion and chemotaxis test, in...

Petroleum ether (40-600), chloroform, alcohol and aqueous extract of Lagenaria vulgaris fruits have been evaluated for its anti-ulcer activity by using pylorus ligation method in rats. Doses for the different extracts were selected based on the results of acute toxicity studies. The effect was assessed by ulcer index, total acidity and free acidity...

Obejective: To study the effect of hydroalcoholic extract of aerial parts of Achyranthes aspera on neutrophil phagocytic function. Methods: The different concentrations (25,50 and 100 mg/ml) of extract of aerial parts of Achyranthes aspera was subjected to study its effect on different in vitro methods of phagocytosis such as neutrophil locomotion...

Objective: To study the hypoglycaemic properties of Ficus glomerata fruits in alloxan induced diabetic rats. Materials and methods: Petroleum ether, benzene, chloroform, ethanol and aqueous extracts of F. glomerata fruits were screened for hypoglycemic properties in alloxan-induced diabetic rats. The effect was assessed by blood glucose, serum chol...

Objective: To study the anti-ulcer activity of stem bark of Shorea tumbuggaia in pylorus ligation method. Materials and method: Petroleum ether (60-80°), chloroform, ethanol and aqueous extract of Shorea tumbuggaia stem bark were tested for various preliminary phytoconstituents and were screened for anti-ulcer activities in pylorus ligation method...

Objective: To screen the wound healing activity of different extracts of leaves of Lawsonia alba on excision, incision wound models in albino rats. Materials and methods: Crude extracts of the leaves of Lawsonia alba obtained by successive solvent extraction with petroleum ether (40-60°C), chloroform, ethanol 95% and finally maceration with chlorof...

Wound healing potential of different extracts of leaves of Lawsonia alba Lam. (Lythraceae) was evaluated on the rat excision and incision wound models. Different routes of administration (oral and topical) were studied in view to evaluate their efficacy in wound management. The naphthaquinone derivative, lawsone was isolated from the leaves and scr...