Kalpana Baghel

• Doctor of Philosophy
• ICMR-Research Associate at Dr. Hari Singh Gour University

Knowledge of the endemic parasite fauna in freshwater fish is of great importance. Parasites may work together to stress the health of their hosts. Therefore, the present study aimed to focus on the impact of nematode parasitism on Clarias batrachus (C. batrachus) fish health. The objectives of the present study are to evaluate injury to tissues an...

Due to its astounding ability to restore injured tissues using biobased nanomaterials, regenerative medicine has engrossed higher consideration in recent years. The physicochemical properties of nanoparticles can be rationally tuned to cause the right biological responses. Cell-to-cell and cell-to-matrix communications require appealing surface cha...

Diabetes is a metabolic disorder whose prevalence has become a worrying condition in recent decades. Chronic diabetes can result in serious health conditions such as impaired kidney function, stroke, blindness, and myocardial infarction. Despite a variety of currently available treatments, cases of diabetes and its complications are on the rise. Th...

Background Niosomes hold promise as drug delivery systems for cancer treatment, with niosome size impacting stability, biodistribution, and effectiveness. This study optimized methotrexate (MTX)-loaded niosome formulation by studying the effects of components and processing conditions on size. The niosomes formulation was made by the thin-film hydr...

Abstract Problem: Reproductive performance of animals gets affected by nutritional restrictions which act as potential stressors leading to hormonal imbalance and testicular inflammation, the major causes of infertility. Withania somnifera (WS), well-known traditional medicinal plant, has been used as antistress and infertility treatment. Therefore...

Packaging has a major impact on ensuring the purity and safety of food, reducing waste and spoilage. Biopolymer-based packaging is a modern alternative to traditional plastic packing systems that is gaining popularity. Cellulose, a material often used in the development of biodegradable/compostable polymers, has become a popular choice for food pac...

Diabetes mellitus (DM) is a chronic metabolic disease, characterized by persistent hyperglycemia resulting from diminished insulin secretion or insulin resistance. The present study evaluated the ameliorative effects of Withaferin-A (WA) on DM-induced reproductive dysfunction in mice. For the same, mice were intraperitoneally injected with Streptoz...

Light has a very important function in the regulation of the normal physiology including the neuroendocrine system, biological rhythms, cognitive behavior, etc. The variation in photoperiod acts as a stressor due to imbalance in endogenous hormones. Estrogen and its receptors ER alpha and beta play a vital role in the control of stress response in...

Osteoporosis is a systemic skeletal disease characterised by low bone mineral density (BMD), degeneration of bone micro-architecture, and impaired bone strength. Cissus quadrangularis (CQ), popularly known as Hadjod (bone setter) in Hindi, is a traditional medicinal herb exhibiting osteoprotective potential in various bone diseases, especially oste...

An increased risk of fracture can be attributed to osteoporosis, which is observed to be caused due to a decrease in bone mass. The incidence and mortality rates of osteoporosis have steadily increased over the world as the world’s population ages. For instance, the overall prevalence of hip fractures has increased by 200% in the previous 30 years,...

In nature, food availability stimulates hypothalamo-pituitary-gonadal (HPG) axis while its scarcity induces stress, which further stimulates hypothalamo-pituitary-adrenal (HPA) axis producing a detrimental effect on the avian reproductive physiology. The present experiment was designed to examine the interaction of stress like food restriction and...

Bone disorders are increasing day by day due to various clinical situations, dietary habits, and the western lifestyle. One such bone defect, resulting in earlier fractures, morbidity, and mortality, is the osteoporosis. From the last two decades, the scientific community is making much effort to prevent and treat osteoporosis and the related bone...

Biomedical wastes (BMWs) are generated by the treatment of living organism as well as during research activities. With the increase of population in developing countries, generation of BMWs is increasing, but with inappropriate disposal management technologies. BMWs pose threats to the humans and also degrade the quality of environment. Handling of...

Light plays important function in the regulation of reproduction in vertebrates including birds. The prolonged long day length exposure causes reproductively inactive state or photorefractoriness in many avian species including Japanese quail. Withania somnifera (WS) is a medicinal plant known to have beneficial effects on stress and infertility. T...

Food and water are closely associated with reproductive willingness in vertebrates. These are important for animals and their non‐availability act as stressors which decrease sex steroid secretion suppressing reproductive behaviour. Oestrogen plays a crucial role in reproduction via its receptors alpha (ERα) and beta (ERβ). This study tested the hy...

Estrogen plays a key role in the regulation of reproductive behavior and control of the neuroendocrine system in both males and females. However, excessive quantity of exogenous estrogen produces a deleterious effect on the male reproductive system. To elucidate the mechanism by which estrogen modulates its receptor alpha (ESR1) in immature chicken...