Kai Faehrmann

Kai Faehrmann
German Center for Neurodegenerative Diseases | DZNE · RG Axon Growth and Regeneration (Bonn)

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Mitochondrial dysfunction is critically involved in Parkinson's disease, characterized by loss of dopaminergic neurons (DaNs) in the Substantia nigra (SNc), while DaNs in the neighboring ventral tegmental area (VTA) are much less affected. In contrast to VTA, SNc DaNs engage calcium channels to generate action potentials, which leads to oxidant str...

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