
Kaan Polatoglu- Ph. D.
- Professor (Assistant) at Altınbaş University, Faculty of Pharmacy
Kaan Polatoglu
- Ph. D.
- Professor (Assistant) at Altınbaş University, Faculty of Pharmacy
About
63
Publications
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Introduction
Goals:
1. Develop natural, environment friendly consumer products and industrial products that could be used in agriculture and food industry (including novel insecticides, rodenticides, beverages) from natural resources.
2. Develop new methods for isolation that increase quality and yield of essential oils.
3. Develop new methodologies for chemotype identification and merge natural product studies with these.
4. Develop new rapid and convenient methods for HPTLC - bioactivity assays.
Current institution
Altınbaş University, Faculty of Pharmacy
Current position
- Professor (Assistant)
Additional affiliations
September 2010 - August 2013
December 2001 - December 2009
Publications
Publications (63)
The essential oil composition of aerial parts of Ruta chalepensis L. was analyzed with GC-MS. Seventy-nine compounds were detected representing 85.93 ± 1.08% (n = 3) of the essential oil. The major components of the essential oil were 2-undecanone 21.52±0.21%, 2-nonanone 18.31 ± 0.27%, and 2-nonyl acetate 13.22%. The highest insecticidal contact to...
Previous reports clearly indicate that different chemotypes of Salvia heldreichiana, S. tomentosa and S. candidissima are present. In current study we have investigated essential oil composition of Salvia candidissima ssp. occidentalis, Salvia heldreichiana from Konya and Salvia tomentosa from Eskisehir, Turkey. In GC/MS analysis 89.30 ± 1.034 % (n...
The essential oil composition and biological activities of Chrysanthemum coronarium L. from three locations in Cyprus were investigated. A total of 35 components were identified in the oils representing 86.2 ± 0.7%–93.8 ± 0.0% (n = 3) of the oils. Camphor 25.2 ± 0.1%–9.1 ± 0.3%, santolinatriene 21.7 ± 0.1%–3.6 ± 0.1%, yomogi alcohol 12.6 ± 0.1%–3.6...
Salvia species are very well known for their uses as herbal tea as well as insecticidal activity of their essential oils against stored product insects. Due to their use as herbal tea, Salvia species could be considered as perfect candidates to develop safe natural insect management agents. In the scope of the present study, the essential oil of ae...
Volatile composition of Chenopodium murale from Değirmenlik and Salamis locations of Cyprus were trapped with headspace solid-phase microextraction (HS-SPME) technique and analyzed by GC-MS. Twenty-one compounds were identified comprising of 80.5% of the volatile sample from the Değirmenlik and twenty-six compounds were identified comprising of 82....
There are very few reports on the phytochemistry of the Arabis L. (Brassicaceae) species in the literature. Here we present essential oil composition of aerial parts of two endemic Arabis species from Cyprus. The essential oils of Arabis purpurea Sm. and Arabis cypria Holmboe afforded very low oil yields (< 0.01% (v/w) yield). Sixty six compounds w...
Crithmum maritimum L. (Apiaceae) is an edible plant that is used in salads or consumed as pickles in Cyprus. In our insecticidal screening study of the plant species of Cyprus, we have studied the insecticidal activity (contact and fumigant toxicity) of the essential oil of Crithmum maritimum against stored product pests Sitophilus granarius L., S....
The essential oil of aerial parts of Helichrysum conglobatum (Viv.) Steudel. (Asteraceae) from Cyprus was analyzed by GC and GC-MS. The essential oil yield was 0.01, v/w. Forty five compounds were identified in the oil comprising 96.1% of the total. The essential oil was mainly composed of sesquiterpene type compounds and oxygenated sesquiterpene d...
There is only a couple of reports indicating essential oil composition of Asphodelus species in the literature. However, from the members of this genus many non-volatile secondary metabolites were isolated. In Cyprus, Asphodelus aestivus Brot. can be found abundantly in all regions of the island. This plant has various ethnobotanical uses in Cyprus...
Essential oils obtained from flowers of Tanacetum mucroniferum Hub.-Mor. & Grierson, leaves of Tanacetum densum (Labill.) Heywood ssp. eginense Heywood, stems of Tanacetum densum (Labill.) Heywood ssp. sivasicum Hub.-Mor. & Grierson were investigated for their cytotoxicity, AChE inhibitory and PRAP activities. We have previously investigated chemic...
Lathyrus species including L. ochrus and L. sativus are known for their food, feed and horticultural uses. Despite their widespread uses and cultivation, there is limited information on their chemistry. Previously, only the essential oil composition of L. rotundifolius, L. vernus and volatiles of L. odoratus have been reported. In the present resea...
Since the mid-1980s significant attention has been given to essential oils for their potential use in alternative pest management of stored products. Existing synthetic pesticides including methyl bromide and phosphine which are used as fumigants for pest management of stored products have serious adverse properties. These include their toxicity ag...
Essential oils obtained from flowers of Tanacetum mucroniferum Hub. - Mor. & Grierson, leaves of Tanacetum densum (Labill.) Heywood ssp. eginense Heywood, stems of Tanacetum densum (Labill.) Heywood ssp. sivasicum Hub. - Mor. & Grierson were investigated for their AChE inhibitory and PRAP activities. We have previously investigated chemical composi...
The essential oil of Inula viscosa (L.) Aiton [Syn.: Dittrichia viscosa (L.) Greuter] (Asteraceae) from Cyprus was investigated for the first time. The aerial parts of the plant (100g) afforded 0.01 mL of essential oil. The composition of the oil was identified by GC, GC-MS analysis. Fifty two compounds were identified in the oil corresponding to 7...
Salvia veneris HEDGE. (Lamiaceae) is an endemic species of Cyprus. This species finds use as an herbal tea in the region by the misidentification instead of S. officinalis. There is no information on the biological activity of S. veneris in the literature. Here we report the biological activities of ethanol extract of this species. The cytotoxicity...
Insecticides of the natural origin are an important alternative to the synthetic insecticides that are being employed for the preserving stored products. The volatiles obtained from T. cinerariifolium (=Pyrethrum cinerariifolium) is being used for many types of insecticidal applications; however there is a very little information on the insecticida...
A further investigation on Tanacetum chilliophyllum var. monocephalum ethyl acetate extract afforded a new triterpene lactone Ulubelenolide (olean-12-ene-3β,10β-olide) (1).The structure of (1) was determined with spectral analysis including FTIR, 1 H, 13 C NMR, APT, DEPT, COSY, HMQC, HMBC, and APCI-MS.
Essential oil composition of Centaurea stenolepis Kerner flowers and stems were investigated
with GC, GC-MS. Flowers and stems of C. stenolepis had very low essential oil yield <0.01 % (v/w). Twenty
eight compounds were identified in the flower oil which represent 53.5 % of the oil. Main components of the
flower oil include caryophyllene oxide 12.6...
Essential oil composition of Centaurea kilaea flowers, stems and C. cuneifolia flowers were investigated by GC, GC/MS. Flowers and
stems of C. kilaea afforded very low essential oil yield <0.01% (v/w). Nineteen and twenty compounds were identified in the flower
and stem oils which represent 59.5% and 77.6% of the C. kilaea oil respectively. The mai...
C. coronarium is a member of Asteraceae family which has extensive edible, folk medicinal, insecticidal uses. This species grows abundantly in vast areas of every region of Cyprus. In order to provide an economic value to this species various biological activity tests were conducted. Extracts of C. coronarium were obtained with various solvents inc...
Salvia veneris Hedge. is an endemic species of Cyprus which finds an ethnobotanical use as an herbal tea in the region. This use is probably misidentification of this species instead of S. officinalis. In the literature there is no information related to any kind of biological activity of this species. Here we report DPPH scavenging, PRAP and AChE,...
Essential oil of edible Lathyrus ochrus L. from Cyprus was investigated by simultaneous GC, GC/MS analyses under the same conditions. Trace amount of oil (0.01> mL) was obtained by hydro distillation of 200 g fresh plants and trapped in 1 mL n-hexane. Twenty components were detected representing 91.5 ± 0.5 % of the oil. The main components of the o...
Water-distilled essential oils from aerial parts of Tanacetum abrotanifolium Druce, and T. macrophyllum (Waldst. & Kit.) Schultz Bip. from Turkey were investigated for their insecticidal and biological activity. Highest contact toxicity against S. granarius was observed for the leaf oil of T. macrophyllum (88.93%). Significantly lower but considera...
Essential oil composition of Centaurea stenolepis Kerner flowers and stems were investigated with GC, GC/MS. Flowers and stems of C. stenolepis had very low essential oil yield <0.01% (v/w). Twenty eight compounds were identified in the flower oils which represent 53.5% of the oil. Main components of the flower oils include caryophyllene oxide 12.6...
Salvia veneris Hedge is an endemic plant of Cyprus which is reported to occur in a very limited region around Kythrea (Değirmenlik) village. In our field studies we have observed this species in a wide area occurring in small but continuous populations between Taşkent to Buffavento in the sides of the mountain road unlike the previous reports. This...
Tanacetum chiliophyllum (Fisch. & Mey.) var. oligocephalum (D.C.) Sosn. collected in Turkey was subjected to phytochemical and biological evaluations in this study. Pure compounds were obtained from ethyl acetate extracts of the stems of the plant material. Structures of isolated compounds were determined using spectral methods. Seven known flavone...
Previous reports on folk medicinal uses and insecticidal activity of the genus Achillea prompted us to investigate selected Achillea species in our ongoing biological activity screening of Asteraceae family. Three Achillea species A. biebersteinii Afan. (collected from two different locations), A. vermicularis Trin. and A. teretifolia Willd. essent...
Water-distilled essential oil from flowers of Tanacetum mucroniferum from Turkey were analyzed by GC and GC-MS. The flower oil of T. mucroniferum was characterized with oxygenated monoterpenes and oxygenated sesquiterpenes. Main components of the oil were 1,8-cineole 21.9 % and camphor 6.4 %. Antioxidant activity of the oil was determined at variou...
A great number of research articles have been focused describing variation in the secondary metabolites of the organisms as chemotypes or chemovariation. However, the present definition and nomenclature of chemotype portray some problems such as: 1) low repeatability of natural product studies if a mixture of chemotypes is used in isolation studies...
Cited By (since 1996):2, Export Date: 18 October 2014
Water-distilled essential oil from flowers of Tanacetum mucroniferum from Turkey were
analyzed by GC and GC-MS. The flower oil of T. mucroniferum was characterized with oxygenated monoterpenes
and oxygenated sesquiterpenes. Main components of the oil were 1,8-cineole 21.9 % and camphor 6.4 %.
Antioxidant activity of the oil was determined at variou...
Water-distilled essential oils from aerial parts of Tanacetum densum (L.) Heywood ssp. eginense Heywood, from Turkey was analysed by GC and GC-MS. T. densum ssp. eginense flower, stem and leaf oils were characterized with camphor (30.9%, 25.7%, 27.7%), 1,8-Cineole (12.4% flower oil), camphene (10.6%, %7.0, flower and leaf oils), bornyl acetate, (9....
Water-distilled essential oils from aerial parts of Tanacetum chiliophyllum (Fisch. & Mey.) Schultz Bip. var.
monocephalum Grierson from Turkey were analyzed by GC and GC/MS. The flower and stem oils were characterized by
camphor (17.3%, 10.4%), 1,8-cineole (8.3%, 2.5%) and unknown compounds M+ 218 (6.6%, 10.4%), M+ 220 (Stem: 9.2%).
Root oil was c...
Water-distilled essential oils from aerial parts of Tanacetum chiliophyllum (Fisch. & Mey.) Schultz Bip. var. chiliophyllum, from two different localities in Turkey were analyzed by GC and GC/MS. The flower and stem oils of T. chiliophyllum var. chiliophyllum collected from Van-Muradiye location were characterized with camphor (32.5%, 36.2%), 1,8-c...
Extracts from aerial parts and roots of Tanacetum L. (emend. Briq.) chiliophyllum (Fisch. & Mey.) var. monocephalum Grierson from Turkey were investigated for their DPPH scavenging activity and contact toxicity against Sitophilus granarius. The ethyl acetate extract of aerial parts yielded a new sesquiterpene lactone 1-epi-chiliophyllin (1) which i...
Extracts from aerial parts and roots of Tanacetum L. (emend. Briq.) chiliophyllum (Fisch. & Mey.) var.
monocephalum Grierson from Turkey were investigated for their DPPH scavenging activity and contact
toxicity against Sitophilus granarius. The ethyl acetate extract of aerial parts yielded a new sesquiterpene
lactone 1-epi-chiliophyllin (1) which i...
In this study, water-distilled essential oils from the flowers of Tanacetum zahlbruckneri and flowers and stems of Tanacetum tabrisianum from Turkey were analysed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The flower oil of T. zahlbruckneri was characterised by the sesquiterpenes germacrene D (29.7%) and spathuleno...
Water-distilled essential oils from aerial parts of Tanacetum argenteum ssp. argenteum and T. densum ssp. amani from Turkey were analyzed by GC and GC/MS. The essential oil of T. argenteum ssp. argenteum was characterized with alpha-pinene 36.7%, beta-pinene 27.5% and 1,8-cineole 9.8%. T. densum ssp. amani was characterized with beta-pinene 27.2%,...
Water-distilled essential oils from flowers and stems of Tanacetum argyrophyllum var. argyrophyllum from Turkey were analyzed by GC and GC/MS. The flower oil of T. argyrophyllum var. argyrophyllum was characterized with camphor 29.7%, borneol 12.0%, 1,8-cineole 8.4% and bornyl acetate 6.1%. Stem oil was characterized with camphor 26.6%, 1,8-cineole...
Water-distilled essential oils from herbal parts of Tanacetum parthenium from two different localities in Turkey were analyzed by GC and GC/MS. The essential oil of T. parthenium collected from Davutpasa-Istanbul location were characterized with camphor 49%, trans-chrysanthenyl acetate 22.1% and camphene 9.4%. Second plant sample is collected from...
Water-distilled essential oils from the aerial parts of Tanacetum densum (L.) Heywood ssp. sivasicum Hub.-Mor. et Grierson from Turkey were analyzed by GC and GC/MS. Tanacetum densum ssp. sivasicum flower and stem oils were characterized with 1,8-cineole (21.1% and 28.3%, respectively), camphor (19.2% and 16.4%, respectively), and borneol (5.8% and...
Water-distilled essential oils from aerial parts of Tanacetum cadmeum (Boiss.) Heywood ssp. orientale Grierson, from two different localities in Turkey, were analyzed by GC and GC/MS. The flower, stem and root oils of T. cadmeum ssp. orientale collected from the Adana location were characterized with α-thujone (25%, 5.2%), cis-linalool oxide (6.8%,...