K K Sardar

K K Sardar
Orissa University of Agriculture & Technology | OUAT · Department of Pharmacology & Toxicology

BVSc & AH, MVSc, PhD (IVRI)

About

65
Publications
18,536
Reads
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302
Citations
Introduction
Involved in teaching,research and extension in the field of veterinary and animal sciences. Area of specialization: Smooth muscle and molecular pharmacology, Pharmacokinetics, Pharmacodynamics, Indigenous medicinal plants and toxicodynamics
Additional affiliations
July 1993 - August 2016
College of Veterinary Science & Animal Husbandry, Bhubaneswar, India
Position
  • Professor
Description
  • Engaged in research on Molecular and Vascular Smooth Muscle Pharmacology, Pharmacokinetics, Pharmacodynamics, Indigenous Medicinal Pharmacology, Veterinary Toxicological studies
May 1993 - November 2016
Orissa University of Agriculture & Technology
Position
  • Professor (Full)

Publications

Publications (65)
Article
Full-text available
This study is conducted to examine the change in pattern of the antibiotic sensitivity profile of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa isolated from the recurrent bovine mastitis cases. A total of 75 mastitis milk samples were screened for the presence of S. aureus (n=52), E. coli (n=37) and Pseudomonas aeruginosa (n=1...
Article
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A study was undertaken to develop a western blot method for detection of immunogenic proteins of fish ectoparasite, Argulus siamensis for its further use as potential vaccine candidates. Argulus antigens were prepared by homogenization and injected to rohu (Labeo rohita) juveniles for development of immune serum. The serum was used to immunostain t...
Article
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Chromatographic techniques can be used to investigate the molecular fingerprinting of the herbal compounds. In the present study, we explore the HPLC-MS and HPTLC finger printing pattern of three fractions (methanol soluble, water soluble, and residual fraction) of hot water leaf extract of Astercantha longifolia (AL) Linn. Nees. Methanolic and res...
Article
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To venture into antibiotics resistance the challenge for the future to safeguard lives of many.
Article
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Aim The effects of N-P-K fertilizers in the form of urea, single super phosphate and muriate of potash on development of free-living stages of Haemonchus contortus were studied. Materials and Methods Five parasite free experimental plots of 1 m×1 m area, each of paddy leaves (15-day-old) and an equal number of Cynodon dactylon grass were infested...
Article
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Aim The present study was conducted to ascertain the prevalence of ketosis in dairy cows in dairy herds, milksheds, and mixed population of milk cows selected randomly in milkshed areas of Odisha state, India. Materials and Methods The investigation was conducted in 280 private dairy herds with variable herd size of 10-15 cows comprising crossbred...
Article
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The genetic architecture of 10 rural poultry populations in two distant tribal districts of Mayurbhanj and Kalahandi of Odisha state in India were studied for 15 quantitative and 11 qualitative characteristics through a field survey. Analysis of dispersion was conducted to test the simultaneous significance of mean differences in above characterist...
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Effect of chronic fluorosis on haemato-biochemical parameters and oxidant-antioxidant equilibrium in cattle of industrial fluorotic zones of district Angul, Odisha, India was studied. Ten fluorotic cattle of visible clinical signs of endemic area and ten healthy cattle of non-fluorotic area were selected for the present study. Plasma fluoride level...
Article
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The aim of this study was to investigate the prevalence and therapeutic management of indigestion in milch cows in and around Bhubaneswar, Odisha. Crossbred milch cows (n=257) with the history of anorexia presented to Teaching Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, OUAT, Bhubaneswar and in private herds in...
Article
In the present study, attempt was made to assess pharmaco-economics of drug administration and utilization pattern in the treatment of mastitis by minimizing irrational use of drug with cost effective supervision and management of mastitis in dairy cows. The drug administration and utilization pattern of treatment of mastitis was studied with mean...
Article
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Asteracantha longifolia, a semi aquatic plant, is distributed widely throughout India including Nepal, Sri Lanka, Burma and Malaysia. The yield of fresh stem of Asteracantha longifolia at i ts pre-flowering stage was observed to be 13.43±0.29%. The hot water extracts yielded 12.95±0.06% of dry weight of stem. The proximate analysis values of stem o...
Article
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The present study is aimed at identification of the traditional medical practices being adopted by the rural folks in the treatment of small ruminant diseases in Bhawanipatna block in Kalahandi district of Odisha state. Extensive field survey in 12 villages (Manoharpur, Medinpur, Sujanpur, Jammunabahal, Balarampur, Sagadia, Ichchapur, Sanakhairamal...
Article
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Aim: The present study was conducted to investigate the important climatic variables affecting production and reproduction in a broiler breeder flock. Materials and Methods: The experiment was conducted for a period of 1 year on colored synthetic female line male and female poultry birds. 630 female progeny and 194 male progenies from 69 sires and...
Article
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in and around Bhawanipatna was carried out through 36 regular and repeated informal visits, and 160 informants residing in these villages were consulted through participatory rural appraisal method. Information was gathered through open interaction and door to door interview, and through personal interrogation. A total of 23 species of herbal plant...
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Aim: The aim was to evaluate and compare the clinico-physiological, hemodynamic and hematobiochemical effects in response to different total intravenous anaesthesia techniques using xylazine or dexmedetomidine with propofol in canine patients. Materials and Methods: Under a prospective randomized blinded clinical study, 12 apparently healthy adult...
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Out of 541 dogs (181 pet and 360 stray) belonging to either sex examined in and around Bhubaneswar during a period of one year (Aug 2011- July 2012) 57 (10.54%) were found positive for haemoprotozoan parasites. Babesia gibsoni, Babesia canis, Hepatozoon canis and Trypanosoma evansi were the four species recorded with percentage of incidence 4.81%,...
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An adverse drug reaction (ADR) is a serious concern for practicing veterinarians and other health professionals, and refers to an unintended, undesired and unexpected response to a drug that negatively affects the patient's health. It may be iatrogenic or genetically induced, and may result in death of the affected animal. The ADRs are often compli...
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A 7 year old Labrador bitch showed the symptoms of polyphagia, polydipsia and bilateral opacity of the lens. The performed clinical and laboratory analysis suggested that the dog was suffering from type-II diabetes mellitus. Following administration of oral hypoglycemic agents viz, glimepiride and acarbose, there was no fall of blood glucose level...
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Aim: To study the prevalence of tick infestation in dogs in and around Bhubaneswar. Materials and Methods: Atotal of 610 dogs (360 stray dogs & 250 pet dogs) in and around Bhubaneswar belonging to either sex were examined for tick infestation during a period of one year (Aug 2011-July 2012). Standard parasitological procedures were followed for col...
Article
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A dog suffering from cutaneous haemangioma was successfully treated with antineoplastic drug cytocristine vinca alkaloid (vincristine - 1ml dose @ 0.025mg/kg body wt) intravenously weekly along with multivitamin and liver supportive on alternate days. The animal was recovered completely after 7 weeks.
Article
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Shorea robusta Gaertn. f. (Sal) is one of the most important traditional Indian medicinal plants. The resin of the plant has been used in the treatment of inflammation in folklore medicine. In the present study, ethanolic extract (70%) of S. robusta resin (SRE) was investigated for its anti-inflammatory and antipyretic activities. Acute inflammatio...
Article
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Shorea robusta (Sal), an important traditional Indian medicinal plant used in various ailments and rituals and the indigenous use of the resin of this plant as a medicament for treatment of various inflammatory conditions is well documented in literature. In the present study, ethanolic extract of S. robusta resin (SRE) was evaluated for its analge...
Article
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Fractions of hot water extract of Asteracantha longifolia Nees leaf and aerial parts were subjected to qualitative and quantitative screening of different phytochemicals and for quantitative determination of different micro and macro elements. Dried leaf powder was analyzed for proximate composition and quantitative determination of different micro...
Article
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The ethanolic extract of S. robusta resin (10 and 30 % w/w applied locally in excised and incised wounds) produced a dose-dependent acceleration in wound contraction and increased hydroxyproline content and tensile strength of wounds in rats. The results demonstrate wound healing activity of ethanolic extract of S. robusta resin.
Article
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Hygrophila spinosa contains several phytoconstituents viz. phytosterols, polyphenols, proanthocyanins, mucilage, alkaloids, flavonoids, terpenoids, glycosides, etc. having haematinic, antidiabetic, anti-nociceptive, hepato-protective, antioxidative and androgenic property with no side effects. In the present text, literatures about ethnomedicinal i...
Article
We investigated egg yolk and albumen for protein, cholesterol, zinc, iron, copper, manganese and potassium from three breeds of backyard poultry. CARI Shyama contained significantly higher percent of albumen (58.57±2.36) than Black Rock (51.74±1.14) and showed lower percent albumen volume than that of Gramapriya (68.47±1.20), Vanaraja (62.50± 1.19)...
Article
Study revealed that the soil of the Jaipur district was deficient in calcium and phosphorus. None of the pasture samples was found to be deficient in any of the macrominerals. Prevalence of deficiencies of Ca and P in the serum was calculated to be 94 and 70% respectively.
Article
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Isolated goat detrusor muscle exhibited spontaneous contractility with an irregular amplitude and frequency. The spontaneity of detrusor muscle exhibited a mean amplitude as 11.99 +/- 0.83 mm and frequency as 1.37 +/- 0.16/min. KATP-channel openers namely, cromakalim or pinacidil (10(-7) - 10(-4) M) added cumulatively, elicited a concentration-rela...
Article
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Nitrovasodilators-sodium nitroprusside (SNP; 10(-9)-10(-4) M) and 3-morpholino-sydnonimine (SIN-1; 10(-9)-10(-4) M) produced concentration-dependent relaxation of the fourth generation sheep pulmonary artery, preconstricted with 5-hydroxytryptamine (1 microM). Oxidizing agents [oxidized glutathione (GSSG, 1 mM) and CuSO4 (5 and 20 microM)] and redu...
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It is concluded that the D-Bloat MPS, a preparation containing synthetic surfactant (Di-methyl polysiloxane) and vegetable essential oils was successful in the treatment of bloat in cattle.
Article
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Segmental heterogeneity in relaxation response to nitric oxide (NO) was examined using NO donor sodium nitroprusside (SNP) in second- (medium) and fourth-generation (small) ovine isolated intralobar pulmonary arteries. In vessels precontracted with serotonin, NO donors SNP and S-nitroso-N-acetylpenicillamine (SNAP) were more potent in relaxing medi...
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The mechanisms of relaxation to nitric oxide (NO)-independent soluble guanylyl cyclase (sGC) activator BAY 41-2272 [5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]pyrimidin-4-ylamine] were investigated in isolated ovine pulmonary artery. BAY 41-2272 (1 nM-10 microM) produced concentration-dependent relaxation of endothelium-de...
Article
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Berenil (diminazene diaceturate) is used extensively to combat trypanosomiosis and babesiosis in cattle, buffalo, sheep and several other domestic animals (Milne et al., 1955; Verma et al., 1973; Pandey and Mishra, 1978; Arowolo and Ikede, 1980 and Singh et al., 1980). The drug contains strongly basic groups which bind the kinetoplast DNA by non-in...
Article
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Aqueous leaf extracts of Eupatorium odoratum Linn. were screened for wound healing effects in rabbits antibacterial effect in different isolates of bacteria. Complete filling and healing of wounds was observed by 11th - 13th day after daily application of the aqueous leaf extract in experimentally created wounds. Similar findings were also observed...

Projects

Project (1)
Project
Documentation of native chicken birds in the districts Identification of desirable phenotypic and genotypic characteristics of native chicken Conservation and propagation of native chicken Registration of native chicken of the district under ICAR-NBAGR Registration of breeders society for farmers’ benefit Future utility of the bird