K. Husnu Can Baser

Near East University · Department of Pharmacognosy

In this study, the essential oil and various extracts (n-hexane, ethyl acetate, and methanol) were obtained from Seseli libanotis W.D.J. Koch aerial parts. The essential oil was obtained via hydrodistillation and subjected to GC and GC/MS analysis. 42 compounds were identified as a major component of acorenone B (43.3%), following by cis-sesquisabi...

Wild growing Origanum majorana L. var. tenuifolium Weston was collected from three different locations (Om1: Avtepe, Om2: Alevkayası, Om3: Kozanköy) in North Cyprus. The essential oils were hydrodistilled and chemical composition analyses were simultaneously performed by GC-FID and GC-MS. The average yields of essential oils were 5.46-8.14%. Major...

Aim of the study is to evaluate the potential use of Thymus capitatus (L.) Hoffm. & Link and Origanum dubium Boiss. essential oils and their major constituents; thymol and carvacrol in cancer therapies. For this aim hMSC-telo1 cells and their tumorigenic counterpart were exposed to varying concentrations of Thymus capitatus (L.) Hoffm. & Link an...

Coldmix ® is a commercially available Eucalyptus aetheroleum and, Abies aetheroleum blend for medicinal applications. In this present study, the in vitro antiviral potential of Coldmix ® , and its major constituents 1,8-cineole and α-pinene were evaluated by using the in vitro ACE2 enzyme inhibition assay as well as the direct contact test against...

The genus Eucalyptus belonging to the Myrtaceae family, consists of tall, evergreen trees with leathery leaves. They are indigenous to Australia and contain about 900 species and subspecies. One important use is production of essential oils, which are valuable in both medicinal and pharmaceutical industries. There are about 62 species of Eucalyptus...

The genera Nigella and Garidella are two members of the Nigelleae tribe. Among all the taxa of the tribe, black cumin (Nigella sativa L.) is one of the most important plants concerning economic and medicinal uses. In this study, volatiles were analyzed in detail to elucidate the phytochemical profiles and to understand the taxonomic patterns of sec...

Anthemis cretica var. leucanthemoides

Rubia tinctorum

Two Lamiaceae species, Satureja icarica P.H. Davis collected from Gokceada (Canakkale) and Satureja pilosa Velen. collected from Kazdag Mt. (Balikesir) are new records for Turkey. Short morphological descriptions including illustrations of the species are given.

Thymus pulvinatus

Salvia smyrnea

Origanum onites L. (O. onites) is one of the cultivated Origanum species in Turkey. The aim of this study was to determine the cytotoxicity and cellular antioxidant effects of O. onites essential oil, carvacrol and p-cymene on HCT116 and HepG2 cells. O. onites essential oil components were analyzed by GC/MS and GC/FID. Cytotoxicity was analyzed via...

A growing number of investigations of essential oils, extracts or phytochemicals have been conducted to discover effective pesticidal agents against Aedes aegypti L., a major vector of yellow fever, Zika fever and dengue. The goal of this study was to enhance the knowledge about the activity of Erica manipuliflora and to discover effective pesticid...

This study was aimed to evaluate the essential oil composition of Chaerophyllum libanoticum fruits and its potential uses in the cosmetic industry. The essential oil was analyzed by Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC/MS) systems, simultaneously. The yield of essential oil was calculated as 0.22 % (v/w). Major compo...

Salvia species have lately gained significant interest as a result of their suitable utilization in various industries. In the current study, S. hydrangea, one of the most consumed sages in the eastern region of Turkey, has been evaluated for phytochemical composition as well as in vitro pharmacological potential comparatively for the first time. T...

Eucalyptus essential oils are well-known and used especially in upper respiratory tract pathologies or diseases as herbal drug preparations. In the present study, the in vitro angiotensin-converting enzyme 2 (ACE2) and lipoxygenase (LOX) enzyme inhibitory potentials of commercial Eucalyptus globulus Labill. and Eucalyptus citriodora Hook. essential...

Teucrium species that belong to the family Lamiaceae have been traditionally used for their medicinal properties. T. polium is one the most widespread members of the genus for its use in the treatment of several diseases. In this study, the essential oil and phenolic composition of the aerial parts from T. polium were assessed by GC-FID, GC/MS, and...

Background: Calcium hydroxide is a routinely used material for root canal disinfection during root canal treatment. Natural products have great potential in terms of their antibacterial effects. This study aimed to establish an effective alternative intracanal medicament using Origanum dubium (O. dubium) and Mentha spicata (M. spicata) essential o...

Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercially Origanum majorana, O. minutiflorum, O. vulgare, and O. onites essential oils, and their prominent constituent carvacrol was evaluated for their in vitro and in silico angiotensin-converting enzyme 2 (ACE2) and lipoxygenase (LOX) enzyme...

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive deterioration of cognitive functions (dementia) and represents a growing public health concern since the population in the age groups at risk is increasing. The latter raises an urgent need to translate research findings in the basic brain and behavioral sciences...

The potential applications of Achillea species in various industries have encouraged the examination of their phytochemical components along with their biological potential. In the present study, phenolic contents and essential oil compositions together with the in vitro biological activities of the aerial parts from Achillea biebersteinii Afan. an...

3,3-Dimethylcyclohexyl methyl ketone (Herbac®) is a fine fragrance compound used in the cosmetic industry. In this study, the biological derivatisation of the substrate 3,3-dimethylcyclohexyl methyl ketone by 18 fungal cultures was carried out to obtain new derivatives. Among the evaluated, the plant fungus Aspergillus niger ATCC 10549, biotransfor...

This study was aimed to evaluate the potential uses of Ferulago longistylis Boiss. essential oils in cosmetic applications. The air dried roots and fruits were subjected to water distillation by using a Clevenger apparatus for 3 h. Both essential oils were analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry(GC/MS) syste...

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive deterioration of cognitive functions (dementia) and represents a growing public health concern since the population in the age groups at risk is increasing. The latter raises an urgent need to translate research findings in the basic brain and behavioral sciences...

As the sixth-largest Angiosperm family, Lamiaceae contains more than 245 genera and 7886 species that are distributed worldwide. It is also the third-largest family based on the number of taxa in Turkey where it is represented by 46 genera and 782 taxa with a high endemism ratio (44%). Besides, Lamiaceae are rich in plants with economic and medicin...

Cedramber (cedrol methyl ether) (1) is a fragrance compound used in cosmetics such as soap, detergents, creams, lotions and perfumes. New cedrol derivatives are of interest in this context. Here we report the first biotransformation reaction of cedramber by Aspergillus niger ATCC 10549. The conversion afforded two known cedrol derivatives namely, 1...

Kişniş (Coriandrum sativum) Kişniş (Coriandrum sativum L.), maydanozgiller (Apiaceae) ailesin-den, 30-90 cm'ye yükselen, tüysüz, aromatik, tek yıllık, otsu bitkidir. Meyveleri, küre biçiminde, 2-7 cm çapında, esmer sarı renkli, özel ko-kulu, baharlı, tatlımsı ve yakıcı lez-zetlidir. Meyvelerinden elde edilen uçucu yağ, koku-tat maddesi ola-rak önem...

Objective: Natural plant products are considered as a source of novel and effective compounds for the treatment of leishmaniasis. In this study, the in vitro activities of essential oils obtained from Origanum dubium (OD), Origanum majorana (OM), Salvia fruticosa (SF) and Laurus nobilis (LN) plants in Northern Cyprus were investigated against Leis...

Zika, dengue, and Yellow fever are transmitted primarily by Aedes aegypti mosquitoes. Investigations to find more natural but highly effective pesticidal agents against Ae. aegypti have increased in the last few years. Plant-based compounds have been the source of several current pesticides and have provided models for creation of synthetic derivat...

24 bağbahçe 95 (mayıs-haziran) 2021 Demirhindi (Tamarindus indica L.), baklagiller (Leguminosae) ailesinden, herdem yeşil ağaçtır. İngilizce, "Tamarind" olan ismi; Farsça, "Hint hurması" anlamında, "Tamar-ı Hind" sözcüğünden gelir. Vatanı Madagaskar olan bit-ki, Mısır, Sudan, Hindistan dâhil, dünyanın tropik ve ılıman kuşaklarında yetiştirilmektedi...

Abstract The genus Artedia L. (Apiaceae) is represented in Turkey by 485 species and altogether 511 taxa. The rate of species endemism in Turkey is 37.7%. The plant material was collected from the province of Kahramanmaraş, Turkey. The essential oils from fruits and aerial parts were obtained by hydrodistillation using a Clevenger type apparatus. C...

Bisabolol is one of the bioactive constituents of chamomile. It was aimed to biotransform (–)-α-bisabolol by different fungi for the production of new bioactive metabolites, which was converted to α-bisabolol oxide A and B by Thamnidium elegans. Additionally, the biotransformation by Penicillium neocrassum yielded a new metabolite, which was charac...

Dunya'nin Bitki ve Mantarlarinin Durumu - 2

Rosa damascena Mill. is a traditional and promising agricultural plant used for manufacturing essential oil in Saudi Arabia. The present study aims at studying the chemical composition, sensory evaluation and antimicrobial activity of some samples of rose oils (Rosa damascena Mill.) from the region of Taif. The chemical composition was determined b...

A headspace-solid phase microextraction (HS-SPME) procedure for isolation and investigation of volatile compounds in hybrid "limequat" and parents "Mexican lime and kumquat" fruits using Gas Chromatography-Mass Spectrometry (GC-MS) for the separation and identification of the volatiles was employed in the present study. Each of mature, fresh and wh...

Boswellia sacra Flueck essential oil is obtained from frankincense obtained from Boswellia sacra trees. The aim of this study was to investigate the in vitro anti-cancer activity of Boswellia sacra (BS) essential oil in CD133+ and CD133- Colo-320 cells. Essential oil was analyzed by GC-MS. CD133+ cells, cancer stem cells, were obtained from the Col...

State of the Plants and Fungi 2020

The chemical composition, free radical scavenging, α-amylase inhibitory, and 5-lipoxygenase inhibitory activity of the essential oil obtained from the aerial parts of Centaurea pterocaula Trautv. were examined. Twenty-nine compounds corresponding to 93.2% of the oil were identified in the oil of C. pterocaula. Hexadecanoic acid (13.9%), caryophylle...

Citrus fruits are cultivated and used as fresh fruits or for the production of juices Worldwide. These fruits are of great interest as raw materials for pharmaceutical, cosmetics and food industries due to their aromatic properties. Residues of the production of citrus juice, such as peels, membranes and seeds, possess a large variety of phytochemi...

In this study two different extraction techniques namely, conventional hydrodistillation (HD) and micro-steam distillation-solid-phase microextraction (MSD-SPME), were used to analyze the volatile constituents from the leaves and the galls of Salvia fruticosa Mill. by gas chromatography (GC-FID) and gas chromatography coupled to mass spectrometry (...

26 bağbahçe 91 (eylül-ekim) 2020 Ginseng (Panax ginseng C.A. Mey. [Araliaceae] [sin. Aralia ginseng Baill., Panax verus Oken]) bitkisinin kökleridir. Asya ginsen-gi, Çin'in kuzeydoğusu, Kore ve Rusya Federasyonu'nun en doğu bölgelerinde yetişmektedir. Çin, Japonya, Kore ve Rusya'da tarımı yapılmaktadır. Bitki, dördüncü yaşında çiçek açmaya başlar v...

In vitro cholinesterase inhibition, antioxidant and anticancer potentials of the essential oils and extracts of flowers and aerial parts of Salvia verticillata subsp. amasiaca have been studied. The GC-MS and GC-FID analyses found that major components of the essential oils were caryophyllene oxide, caryophylladienol II, spathulenol, hexahydrofarne...

The chemical compositions of the essential oils obtained by hydrodistillation from aerial parts of five subspecies of Scutellaria orientalis L. (subsp. carica, subsp. haussknechtii, subsp. macrostegia, subsp. orientalis and subsp. santolinoides) were analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS), simultane...

This investigation displays antioxidant potential of Cymbocarpum erythraeum essential oils and their biological effects like cytotoxic and anticholinesterase. The antioxidant capacities of the essential oils were estimated by DPPH, TBA, TOS assays. The anticholinesterase activity of essential oils was estimated utilizing Ellman method. The human U-...

The volatile oils of fresh and air-dried buds of 3 different varieties of Cannabis, namely, high cannabidiol (CBD) chemotype, intermediate CBD/tetrahydrocannabinol (THC) chemotype, and high THC chemotype were prepared by hydrodistillation. Gas chromatography analysis of the volatile oils resulted in the identification of 71 compounds, of which 33 w...

Karabuğday (Buckwheat)

In the current work the flowers of green and dark purple Ocimum basilicum L. varieties cultivated in Uzbekistan were comparatively studied in terms of chemical composition of the lipids, essential oils and fatty acids by using TLC, GC-FID and GC-MS techniques. The lipid composition of flowers both basil varieties comprised biologically active subst...

The oxidant, cholinesterase, and carbonic anhydrase inhibitions of essential oils and their major compounds of Leiotulus dasyanthus and molecular docking studies of α-pinene and ™-3-carene were evaluated in this study. Phenolic constituents and antioxidant activity of samples were determined by Folin-Ciocalteu’s, DPPH, and TBA processes. Cholineste...

The genus Bunium (Apiaceae) comprises about 50 species spreading in Asia, Europe and North Africa. It is encountered in almost every region of Turkey, especially in the Mediterranean, Southeastern Anatolia and Eastern Anatolia regions. It has various therapeutic effects on digestive and urinary tract disorders. In traditional medicine, it has been...

The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase activities were performed. The oil was analyzed both by gas chromatography-mass spectrometry and gas chromatography-flame ionization d...

The present study reports chemical composition, antidiabetic, anti-inflammatory and antioxidant potential of essential oils from leaves and twigs of Myrtus communis L. subsp. communis from Turkey. Essential oils were obtained separately from leaves and twigs of Myrtus communis subsp. communis (MC) by hydrodistillation using a Clevenger-type apparat...

28 bağbahçe 88 (mart-nisan) 2020 Bamya (Abelmoschus esculentus [L.] Moench. [Sin. Hibiscus esculentus L.; Abelmoschus bammia Webb]), ebegümecigiller (Malvaceae) familyasına dâhil, otsu bitkidir. Vatanının, Etiyopya olduğuna inanılan bitkinin; Türkiye, Güney Avrupa, Batı Afrika, Orta Doğu, Hindistan, Çin ve Amerika kıtasında, yaygın tarımı yapılmakt...

Sedir yağı (Cedri aetheroleum)

Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential of Turkish Origanum onites L. oil and its major constituents against a panel of parasitic protozoa. The essential oil was obtained by hydrodistillatio...

Non-polar and polar compounds were isolated from the leaves and chemical composition of the essential oil from aerial parts of Sideritis cypria endemic in Northern Cyprus was also determined. The structures of all the isolated compounds were elucidated by means of spectroscopic (UV, NMR: 1D and 2D-NMR: 1H, 13C, COSY, HSQC, HMBC) methods and compari...

The genus Nigella L. s.l. (Ranunculaceae) is one of the most important plants in respect of economic and medicinal usage. Fatty acid compounds have been researched in detail for the taxa of Nigella s.l., naturally growing in Turkey. Among them, 19 Nigella taxa were researched in respect of 18 fatty acid compounds. These were acquired by the way of...

Essential oil and lipids from leaves of Ferula kuhistanica Korovin (Apiaceae; syn. F. jaeschkeana auct. non Vatke) growing in Uzbekistan were studied for the first time using GC-MS. Essential oil consisted of 51 constituents (99.8% total with mostly α-pinene, 72.9%). Enantioselective analysis of essential-oil constituents found the enantiomeric exc...

Havuç (Daucus carota L. [Maydanozgiller, Apiaceae]) 20-60 cm'ye kadar büyüyen, iki yıllık, çiçekli bitkidir. Bitkinin, kızıl-turuncu renkli kazık kökü, karotence zengindir ve sebze olarak kullanılır. Avrupa'da, Asya'nın batısında ve Pakistan'da doğal olarak yetişir. Halen tüm dünyaya yayılmış olan bitkinin, her yerde tarımı yapılmaktadır. Havuç mey...