Justin JM Wong

Justin JM Wong
Queen's University | QueensU · Department of Pathology and Molecular Medicine

BSc(Honours, Biochemistry)

About

6
Publications
392
Reads
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51
Citations
Citations since 2016
6 Research Items
51 Citations
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Introduction
A PhD at Queen’s University, Department of Pathology and Molecular Medicine, with a skillset specific to the healthcare and scientific research field including experience with SickKids Hospital, University of Toronto, the Oakville Trafalgar Memorial Hospital, and St John’s Ambulance/Toronto EMS. I am currently writing software to investigate miRNA profiles in neuroendocrine tumors. Last updated May 2018. Full CV available on my website: http://justinjmwong.github.io
Additional affiliations
January 2018 - present
Queen's University
Position
  • PhD Student
January 2018 - April 2018
Queen's University
Position
  • Research Assistant
Description
  • Path 828 - Bioinformatics for Cancer Research
September 2016 - December 2016
Queen's University
Position
  • Research Assistant
Description
  • Biol 205 - Mendelian and Molecular Genetics
Education
January 2018 - December 2022
Queen's University
Field of study
  • Pathology and Molecular Medicine
January 2016 - December 2017
Queen's University
Field of study
  • Pathology and Molecular Medicine
September 2011 - December 2015
Queen's University
Field of study
  • Biochemistry

Publications

Publications (6)
Article
Full-text available
Lung carcinoids are variably aggressive and mechanistically understudied neuroendocrine neoplasms (NENs). Here, we identified and elucidated the function of a miR-375/yes-associated protein (YAP) axis in lung carcinoid (H727) cells. miR-375 and YAP are respectively high and low expressed in wild-type H727 cells. Following lentiviral CRISPR/Cas9-med...
Article
Full-text available
Lung neuroendocrine neoplasms (NENs) can be challenging to classify due to subtle histologic differences between pathological types. MicroRNAs (miRNAs) are small RNA molecules that are valuable markers in many neoplastic diseases. To evaluate miRNAs as classificatory markers for lung NENs, we generated comprehensive miRNA expression profiles from 1...
Article
Full-text available
Neuroendocrine neoplasms (NENs) are clinically diverse and incompletely characterized cancers that are challenging to classify. MicroRNAs (miRNAs) are small regulatory RNAs that can be used to classify cancers. Recently, a morphology-based classification framework for evaluating NENs from different anatomical sites was proposed by experts, with the...
Article
Human brain is a complex organ comprising multiple cell types of differing function. Although histological evaluation remains the mainstay approach for evaluating tissue, comprehensive molecular characterization is now possible due to advanced -omic approaches. microRNAs (miRNAs) are small (~22 nt) RNA molecules that regulate gene expression and me...
Article
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) can be challenging to evaluate histologically. microRNAs (miRNAs) are small RNA molecules that often are excellent biomarkers due to their abundance, cell-type- and disease-stage specificity, and stability. To evaluate miRNAs as adjunct tissue markers for classifying and grading well-different...

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Projects

Project (1)
Project
We use small RNA-sequencing to generate profiles of neuroendocrine neoplsams, and data mine these profiles to find predictors of grade, metastasis, and pathological type.