Jure Mirat

Jure Mirat
University of Osijek | UNIOS · Poliklinika Kardioton

Prof. MD PhD, FESC

About

40
Publications
7,386
Reads
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270
Citations
Additional affiliations
February 2013 - present
Poliklinika Kardioton
Position
  • Direktor
May 1997 - July 2003
Klinička bolnica Dubrava
Position
  • Head of Interventional Cardiology
March 1991 - April 1997
General Hospital Sveti Duh
Position
  • Cardiologist

Publications

Publications (40)
Article
Full-text available
Background: Measuring the quality of life (QoL) of women with breast cancer is an important aspect of measuring treatment success. In Croatia, no QoL studies have been carried out with a focus on patients after mastectomy. The aim of this study was to examine QoL 1 month and 1 year after mastectomy. Methods: This cross-sectional single-center st...
Article
Novel oral anticoagulants (NOACs) are becoming a therapy of choice in everyday clinical practice after almost 50 years during which warfarin and related coumarin derivatives were used as the main anticoagulants. Advantages of NOACs over standard anticoagulants include their predictable pharmacodynamics and pharmacokinetics, stable plasma concentrat...
Article
Background: Minimally invasive direct coronary artery bypass grafting (MIDCAB) was developed to decrease perioperative morbidity, some of which may be related to the use of cardiopulmonary bypass and to cross-clamping of the aorta. We report our initial experience with multivessel MIDCAB via distal mini-sternotomy (DIMS). DIMS is performed to gain...
Data
Full-text available
The Republic of Croatia, with a gross domestic product per capita of US$11,554 in 2008, is an economically less-developed Western country. The goal of the present investigation was to prove that a well-organized primary percutaneous coronary intervention network in an economically less-developed country equalizes the prospects of all patients with...
Conference Paper
Full-text available
A change of the paradigm in the treatment of some diseases rarely changed so radically as the strategy for the treatment of acute myocardial infarction (AMI) has changed over the last few decades. A long period with a completely passive and expectative attitude was followed by two radical revolutions. The first occurred in the eighties by introduci...
Article
Objective of this study was to assess platelet response to clopidogrel and its association with certain single nucleotide polymorphisms (SNPs) of the P2RY12 gene. Several studies have shown that patients with poor in vitro response to clopidogrel have worse outcomes after coronary interventions. Pharmacological response to clopidogrel is mediated b...
Article
Full-text available
The aim of the study was to evaluate the influence of door-to-balloon time and symptom onset-to-balloon time on the prognosis of patients with acute ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) in the Croatian Primary PCI Network. A total of 1190 acute STEMI patients treated with primary P...
Article
Full-text available
Radna skupina za bolesti srËanih zalistaka, Hrvatsko kardioloπko druπtvo Hrvatsko druπtvo za kardiotorakalnu kirurgiju i anesteziologiju A cquired valvular heart diseaes are less common than coronary artery disease (CAD), heart failure and hy-pertension 1 . However, significant changes in occurren-ce of acquired heart valve diseaes have occurred ov...
Article
The aim of this article was to investigate the prevalence of overweight and obesity using selected anthropometric variables in a sample of hospitalized coronary heart disease (CHD) patients in Croatia (N = 1,298). Prevalence of overweight and obesity in surveyed patient population was high: 48.2% of participants were overweight and 28.6% were obese...
Article
Full-text available
The Republic of Croatia, with a gross domestic product per capita of US$11,554 in 2008, is an economically less-developed Western country. The goal of the present investigation was to prove that a well-organized primary percutaneous coronary intervention network in an economically less-developed country equalizes the prospects of all patients with...
Article
Full-text available
Although osteoporosis in men is an increasing health problem, studies on osteoporosis in males are still scarce. The aim of our study was to determine the characteristics of bone tissue and bone turnover in men with idiopathic osteoporosis. Transiliac crest bone samples were histomorphometrically analyzed after double tetracycline labeling in 32 me...
Article
Full-text available
Interrupted aortic arch (IAA) is a congenital defect characterized by loss of luminal continuity between the ascending and descending aorta1. It is a rare malformation with an estimated incidence of perinatally diagnosed cases of 3 per million live births3. The condition is considered extremely rare in adults. However, its true prevalence in this p...
Article
Full-text available
Acute coronary syndrome, although unique in its pathophysiologic mechanism, in its different clinical presentations is characterized by different diagnostic and therapeutic approaches. Conservative approach is complementary rather than competitive to modern invasive percutaneous procedures on coronary arteries. The guidelines are clear but have bee...
Article
Full-text available
Aim This study was performed to determine whether the ratio (Q =A/B) of area A under the curve of exercise systolic blood pressure(SBP) increase and area B under curve of recovery SBP decreaseis predictive of angiographic coronary artery disease (CAD).Methods Patients who performed exercise testing and subsequentlyunderwent coronary angiography, wi...
Article
Full-text available
The aim of this study was to determine the association of bleeding as a complication of warfarin therapy with polymorphism of CYP2C9 gene (alleles 1, 2 and 3). The CYP2C9 is the main enzyme for warfarin metabolism. Study included 181 patients receiving warfarin for at least one month. Allele 1 of CYP2C9 gene (in 94.5%) and genotype *1/*1 (57.5%) pr...
Article
Full-text available
The aim of this investigation was to determine the effect of exercise training on the levels of plasma cytokines and acute phase reactants in the early post acute myocardial infarction (AMI) period. Sixty patients were enrolled into this three-week cardiac rehabilitation study. The mean time from AMI was 7.08 +/- 1.60 days, and the patient mean age...
Article
Full-text available
The aim of this investigation was to determine the seroprevalence of H. pylori in patients with coronary artery disease (CAD). Patients with coronary artery disease (n = 90) and control group (n = 90) were enrolled into this randomized, multi-centre study. CAD risk factors analyzed included age, male gender, diabetes mellitus, systemic hypertension...
Article
Full-text available
The aim of the study was to assess the relationship between systolic blood pressure during maximal treadmill test (SBP9mtt)) and flow-mediated vasodilation (FMD). Abnormal rise of SBP(mtt) is the phenomenon more frequent in hypertensive persons but it could be found in normotensive subjects too. 199 subjects referred to treadmill test were enrolled...
Article
Full-text available
Erectile dysfunction is a common problem whose relation to cardiovascular diseases has scientifically been proved, but it has not been studied sufficiently in patients recovering from myocardial infarction. The objective of this study was to establish the frequency of erectile dysfunction in patients recovering from myocardial infarction. We examin...
Article
Cardiovascular diseases represent the leading health problem of the modern age. They are the first cause of mortality in developed as well as in transition countries. Physical activity has a beneficial impact on the cardiovascular system, both directly by improving endothelial function and indirectly by normalizing risk factors of atherosclerosis,...
Article
Endothelial dysfunction (ED) is actively involved in the mechanism of occurrence, development and progression of all the degrees of atherosclerosis. The established impact of ED on the progress and outcome of cardiovascular diseases, together with convincing indications of a possible successful therapeutic modification, necessitate the changeover o...
Article
Endothelial dysfunction is the essential occurrence in an early phasis of atherogenic process, pointing at the first functional disturbances of cardiovascular system at endothelial level. By the assessment of endothelial dysfunction, subjects with the increased risk for cardiovascular incidents in preclinical phasis, can be selected. Non-invasive a...
Article
Inflammation is a component of atherosclerotic plaque, but it is also a possible pathogenetic factor of acute coronary event responsible for coronary instability. Inflammatory markers are considered as new risk factors for atherosclerosis. Among others (C-reactive protein (CRP) is the best known marker of inflammatory response which is most frequen...
Article
The incidence of atrial fibrillation (AF) is growing worldwide and producing significant morbidity and mortality. Biatrial pacing has been shown to reduce AF and we hypothesized that pacing the atrial septum using an active fixation lead would produce a similar result by pacing both atria simultaneously.
Article
The aim of this study was to determine prevalence of vascular incidents (myocardial infarction and stroke) in parents of subjects who have hipertensive reaction (HR) during exercise testing.
Article
The aim of this study was to examine relationships between total cholesterol, LDL, HDL cholesterol, triglycerides and age, gender, and cigarette smoking in 190 patients (132 men and 58 women) aged 34-87 years with first AMI. The control group included 103 patients (57 men and 46 women) aged 29-90 years without a history of angina pectoris or AMI. H...
Article
Unlabelled: The effects of magnesium (Mg) on the incidence of arrhythmias and on mortality were evaluated in 61 patients with documented acute myocardial infarction (AMI), in a randomized, double blind placebo controlled study. During the first 24 hours 31 patients received infusion of 1000 ml isotonic saline with 17 g MgSO4 and 30 ones received o...
Article
During the period of air-raid alarms in Zagreb (September 1991), the influence of war-induced stress on the incidence and mortality of acute coronary artery disease was investigated. Control periods were September 1989 and September 1990. Among 2903 patients admitted to Emergency Care Units, 369 (13%) were examined for suspect acute coronary artery...

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