Julio Fuchs

Julio Fuchs
Universidad de Buenos Aires | UBA · Department of Biological Chemistry

About

26
Publications
6,403
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456
Citations
Citations since 2017
7 Research Items
253 Citations
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201720182019202020212022202301020304050

Publications

Publications (26)
Preprint
Co-exposure soil studies of pollutants are necessary for an appropriate ecological risk assessment. Here, we examined the effects of two-component mixtures of metal oxide nanoparticles (NPs, ZnO or goethite) with chlorpyrifos (CPF) under laboratory conditions in short-term artificial soil assays using Eisenia andrei earthworms. We evaluated effects...
Article
Full-text available
A novel assay technique that involves quantification of lysozyme (Lys) through machine learning is put forward here. This article reports the tendency of the well- documented Ellington group anti-Lys aptamer, to produce aggregates when exposed to Lys. This property of apta-aggregation has been exploited here to develop an assay that quantifies the...
Article
Full-text available
The effects of mixtures of nanoparticles (NPs) and other chemicals have been poorly studied in terrestrial invertebrates. In this study, we investigated the effects of binary mixtures of goethite (α-FeOOH) NPs and metallic (Cd and Pb) or organic (chlorpyrifos, CPF) contaminants in Eisenia andrei earthworms. We used the filter paper contact test to...
Article
Lead (Pb) is an environmental and industrial contaminant that still represents a public health problem. In this paper, we investigated the effect of Pb on proliferation, lipid peroxidation and the number of micronucleated cells in exponentially growing 3T3-L1 fibroblasts, a cell line previously used to evaluate different environmental contaminants....
Data
Table S1. Questions submitted from Latin American scientists and engineers and examined during a synthesis workshop in Buenos Aires, Argentina.
Preprint
Full-text available
The Global Horizon Scanning Project (GHSP) is an innovative initiative that aims to identify important global environmental quality research needs. Here we report 20 key research questions from Latin America (LA). Members of the Society of Environmental Toxicology and Chemistry (SETAC) LA and other scientists from LA were asked to submit research q...
Article
Full-text available
The Global Horizon Scanning Project (GHSP) is an innovative initiative that aims to identify important global environmental quality research needs. Here we report 20 key research questions from Latin America (LA). Members of the Society of Environmental Toxicology and Chemistry (SETAC) LA and other scientists from LA were asked to submit research q...
Article
Contamination by 2,4,6-trinitrotoluene (TNT) is a global environmental problem at sites of former explosive production, handling, or storage, and could have deleterious consequences for human and ecological health. We investigated its sublethal effects to Eisenia fetida, using two nonspecific biomarkers. In coelomocytes of earthworms exposed 24, 48...
Article
Full-text available
The objective of this work was to evaluate the effects of chlorpyrifos on earthworms and on soil functional parameters. An integrated laboratory-field study was performed in a wheat fi eld in Argentina, sprayed with chlorpyrifos at two recommended application rates (240 or 960 g ha-1 a.i.). Laboratory tests included neutral red retention time, come...
Article
Full-text available
Background, Aim and ScopeContinuous application of pesticides may pollute soils and affect non-target organisms. Soil is a complex ecosystem; its components can modulate the effects of pesticides. Therefore, it is recommended to evaluate the potential environmental risk of these compounds in local conditions. We performed an integrated field-labora...
Article
Full-text available
The contamination of soils and groundwater with explosives represents an important public health and environmental problem. Among the different classes of explosives trinitrotoluene (TNT) constitutes an important contaminant. It has caused toxicity to exposed workers. As in recent times knowledge was gained that the disposal of TNT produced at the...
Article
Full-text available
Estudios anteriores demostraron que extractos metanólicos de hojas verdes de Vallesia glabra presentan propiedades anti-insectos y toxicidad aguda en Artemia salina, posiblemente por interferencia con las fuentes de energía celular. En este trabajo se presentan resultados de estudios de genotoxicidad mediante el Ensayo Cometa de extractos de la mis...
Article
La electroforesis alcalina de células aisladas en gel de agarosa o “Ensayo Cometa”, es un procedimiento de elevada sensibilidad con el que se puede determinar la frecuencia de roturas de simple cadena y sitios modificados en el ADN de las células expuestas a la acción de un agente contaminante genotóxico. En este trabajo se evalúo la sensibilidad y...
Conference Paper
he alkaline single cell gel electrophoresis (Comet assay), is a highly sensitive procedure, which allows quantitating the frequency of DNA single strand breakage and alkali labile sites, on cells exposed to a genotoxic contaminant. In this work, we evaluated the sensitivity and reproducibility of the Comet Assay on coelomocytes of earthworms expose...

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