Julien Potet

Julien Potet
Doctors Without Borders · Access Campaign

About

27
Publications
7,751
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691
Citations
Citations since 2016
18 Research Items
606 Citations
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2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120

Publications

Publications (27)
Article
Full-text available
Snakebite envenoming is a public health concern in many countries affected by humanitarian crises. Its magnitude was recognized internationally but associations between snakebite peaks and humanitarian crises were never clearly established or analysed. This scoping review searched any available evidence of this hypothesized association between snak...
Article
Full-text available
Access to safe, effective, quality-assured antivenom products that are tailored to endemic venomous snake species is a crucial component of recent coordinated efforts to reduce the global burden of snakebite envenoming. Multiple access barriers may affect the journey of antivenoms from manufacturers to the bedsides of patients. Our review describes...
Article
Full-text available
Background Snakebite envenoming kills more than more than 20,000 people in Sub-Saharan Africa every year. Poorly regulated markets have been inundated with low-price, low-quality antivenoms. This review aimed to systematically collect and analyse the clinical data on all antivenom products now available in markets of sub-Saharan Africa. Methodolog...
Article
Full-text available
Objectives To understand stakeholders’ perceptions of the access barriers to quality-assured diagnostics and medicines for leishmaniasis in the high-burden region of eastern Africa, and to identify key bottlenecks to improve the supply of commodities for neglected tropical diseases. Design Desk reviews and qualitative in-depth interview study with...
Article
Full-text available
Background Snakebite has only recently been recognized as a neglected tropical disease by the WHO. Knowledge regarding snakebites and its care is poor both at the population level, and at the health care staff level. The goal of this study was to describe the level of knowledge and clinical practice regarding snakebite among health care staff from...
Article
Full-text available
Introduction Cutaneous leishmaniasis (CL) is the most frequent form of leishmaniasis, with 0.7 to 1.2 million cases per year globally. However, the burden of CL is poorly documented in some regions. We carried out this review to synthesize knowledge on the epidemiological burden of CL in sub-Saharan Africa. Methods We systematically searched PubMe...
Data
Key information from the studies included in this review. (DOCX)
Poster
Full-text available
Snakebite envenoming kills more than 20,000 people in sub-Saharan Africa every year. Three major syndromes are observed: cytotoxic, haematotoxic, and neurotoxic.
Article
Full-text available
Miltefosine, the only oral drug approved for the treatment of leishmaniasis—a parasitic disease transmitted by sandflies—is considered as a success story of research and development (R&D) by a public-private partnership (PPP). It epitomises the multiple market failures faced by a neglected disease drug: patients with low ability to pay, neglect by...
Article
Full-text available
Background: While our previous work has shown that replacing existing vaccines with thermostable vaccines can relieve bottlenecks in vaccine supply chains and thus increase vaccine availability, the question remains whether this benefit would outweigh the additional cost of thermostable formulations. Methods: Using HERMES simulation models of th...
Article
Full-text available
Somalia, ravaged by conflict since 1991, has areas endemic for visceral leishmaniasis (VL), a deadly parasitic disease affecting the rural poor, internally displaced, and pastoralists. Very little is known about VL burden in Somalia, where the protracted crisis hampers access to health care. We reviewed evidence about VL epidemiology in Somalia and...
Article
Full-text available
Background Malaria treatment is recommended for patients with suspected Ebola virus disease (EVD) in West Africa, whether systeomatically or based on confirmed malaria diagnosis. At the Ebola treatment center in Foya, Lofa County, Liberia, the supply of artemether–lumefantrine, a first-line antimalarial combination drug, ran out for a 12-day period...
Article
Full-text available
Of the 24 neglected tropical diseases (NTDs) and conditions listed by WHO, snakebite is among the top killers [1]. Tens of thousands of people die each year as a result of snakebite envenoming, with close to 50,000 deaths in India alone [2] and up to 32,000 in sub-Saharan Africa [3]. Yet there are few sources of effective, safe, and affordable anti...
Article
As a medical humanitarian organisation diagnosing and treating people with neglected diseases for almost 30 years,1 2 Medecins Sans Frontieres (MSF) understands only too well that the dearth of research and development for new tools to treat these diseases3 is directly attributable to insufficient funding and incentives. Innovative incentive mecha...
Article
Full-text available
Treatment of second-stage gambiense human African trypanosomiasis relied on toxic arsenic-based derivatives for over 50 years. The availability and subsequent use of eflornithine, initially in monotherapy and more recently in combination with nifurtimox (NECT), has drastically improved the prognosis of treated patients. However, NECT logistic and n...
Conference Paper
Full-text available
Background / Purpose: Buruli ulcer (BU) disease, a cutaneous infection caused by Mycobacterium ulcerans , is associated with significant morbidity and functional disability worldwide. The identification of alternative antimicrobials or novel agents with simplified delivery of care for BU treatment is a high priority. We aim to assess the current...
Article
Full-text available
Doctors Without Borders (Médecins Sans Frontières) has developed an advocacy agenda in Cameroon to better meet its patients' needs and to simplify control of Buruli ulcers. This agenda is based on 4 priorities: diagnostic (development of a clinical score), chemotherapeutic (to envision drug administration at home, without daily hospital visits), dr...
Article
Full-text available
Background Despite great progress towards malaria control, the disease continues to be a major public health problem in many developing countries, especially for poor women and children in remote areas. Resistance to artemisinin combination therapy (ACT) emerged in East Asia. Its spread would threaten the only effective malaria treatment currently...
Article
Full-text available
Human African trypanosomiasis (HAT), also known as “sleeping sickness”, is a parasitic disease that is fatal if left untreated. The disease is transmitted by the tsetse fly and is endemic to sub-Saharan Africa, where it mainly affects impoverished rural communities. There are two forms of HAT; the West African variant caused by Trypanosoma brucei g...
Article
Full-text available
Introduction: Leishmaniasis is a parasitic disease transmitted by phlebotomine sandflies. Between 700,000 and 1.2 million cases of cutaneous leishmaniasis and between 200,000 and 400,000 cases of visceral leishmaniasis (VL), which is fatal if left untreated, occur annually worldwide. Liposomal amphotericin B (LAMB), alone or in combination with oth...

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