Julien HeringTree of Science · Science 2.0 - Open Science
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CEO & founder of Tree of Science (www.treeofscience.com), PhD in neuroscience with 10 years experience in research and academic teaching – Training, consulting, coaching in digital research tools and scientific networks (science 2.0), professional networking, digital strategy for all researchers (from PhD students, academic PhDs to R&D researchers) and research organizations.
May 2009 - June 2012
- Specialist in electrophysiology and ion channels
- - Expertise in electrophysiology and ion channels - Up to date awareness of the state-of-the-art theories, scientific knowledge, technological developments, and competitive aspects in electrophysiology and ion channels.
November 2000 - June 2004
Université Pierre et Marie Curie (Paris VI)
Field of study
Open science and science 2.0 : the keys for the future of biomedical researches Biomedical researchers are facing stronger challenges every year since the never-ending increase of complexity in life sciences. Basic, pharmaceutical, and medical researchers need to find a way to overcome the huge costs of experiments, the reproducibility crises that...
Ca2+ entry into neuronal cells is modulated by the activation of numerous G-protein-coupled receptors (GPCRs). Much effort has been invested in studying direct G-protein-mediated inhibition of voltage-dependent CaV2 Ca2+ channels. This inhibition occurs through a series of convergent modifications in the biophysical properties of the channels. An i...
Despite the marked influence on neuronal physiology of the low-voltage activated T-type Ca(2+) currents, little is known about the intracellular pathways and neurotransmitters involved in their regulations. Here, we report that in thalamocortical neurons a phosphorylation mechanism induces an increase both in the current amplitude (1.5 +/- 0.27-fol...
T-type calcium channels (the Ca(V)3 channel family) are involved in defining the resting membrane potential and in neuronal activities such as oscillations and rebound depolarization. Their physiological roles depend upon the channel activation and inactivation kinetics. A fast inactivation that stops the ionic flux of calcium in tens of millisecon...
Intracellular Ca2+ concentration controls a number of physiological functions some of which are initiated at quite negative membrane potentials (-80 mV to -50 mV). Such is the case for the oscillations recorded in thalamic neurons, but also in non-excitable cells, for spermatozoid capacitation, terminal differentiation of myoblasts or aldosterone s...
De nombreux processus physiologiques sous le contrôle du Ca2+ intracellulaire surviennent à des potentiels membranaires proches du potentiel de repos. A ces potentiels, les canaux calcium de type T sont des acteurs privilégiés du contrôle calcique, capables d’engendrer soit un courant dépolarisant de grande amplitude mais transitoire, soit un coura...
" A 'nano' era for electrophysiology" (Nature Methods) - A new powerful approach to study individual role of neurons in a network (or cardiomyocytes) by long -lasting intracellular recordings. Interesting to follow up !
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