Julien Guevar

Julien Guevar
Universität Bern | UniBe · Department of Clinical Veterinary Science

DVM MVM DECVN MRCVS

About

67
Publications
13,127
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
371
Citations

Publications

Publications (67)
Article
Objectives: The main aim of this study was to evaluate the feasibility of minimally invasive stabilization with polyaxial screws-rod using neuronavigation and to assess accuracy and safety of percutaneous drilling of screw corridors using neuronavigation in thoracolumbar spine and compare it between an experienced and a novice surgeon. Study desi...
Article
Background: As they have been seldomly described in the veterinary literature, the aims of this retrospective study were to describe the clinical presentation, MRI findings and long-term outcome after medical or surgical treatment of dogs presenting with foraminal and far lateral thoracolumbar intervertebral disc herniations. Methods: Retrospect...
Article
Full-text available
Background: Lymphoma is the most common spinal cord neoplasm and second most common intracranial tumor in cats, but description of specific magnetic resonance imaging (MRI) features is lacking. Objective: Describe the clinical and MRI features of lymphoma affecting the central (CNS) or peripheral (PNS) nervous system or both in cats. Animals:...
Article
A 3‐year‐old spayed female German Shepherd dog was presented for investigation and treatment of a firm slow growing mass over the right surface of the skull. Computed tomography (CT) of the head revealed a proliferative, rounded and well‐defined compact bone mass expanding extracranially. A right rostrotentorial craniectomy was performed with ‘en b...
Article
Objective The aim of this study was to validate an imaging technique for evaluation of spinal surgery accuracy and to establish accuracy and safety of freehand technique in the thoracolumbar spine of large breed dogs. Study Design After thoracolumbar spine computed tomography (CT), 26 drilling corridors were planned then drilled to receive 3.2 mm p...
Article
OBJECTIVE To describe a modified approach to neurologic examination of African pygmy hedgehogs (Atelerix albiventris). ANIMALS 12 adult hedgehogs (7 males and 5 females). PROCEDURES Aspects of the standard neurologic examination of dogs and cats were evaluated for use with awake hedgehogs, and modified approaches to evaluating their normal behavi...
Article
Full-text available
A 7-month-old, spayed female, domestic longhair cat with L-2-hydroxyglutaric aciduria (L-2-HGA) was investigated. The aim of this study was to investigate the clinical signs, metabolic changes and underlying genetic defect. The owner of the cat reported a 4-month history of multiple paroxysmal seizure-like episodes, characterized by running around...
Article
Objective To assess the accuracy of three‐dimensionally (3‐D) printed drill guides in constraining the trajectory of drill tracts for implants in canine thoracic vertebrae. Study design Experimental ex vivo study. Sample population Five canine thoracic vertebral column specimens. Methods Guides to constrain drill trajectories were designed on th...
Article
Objective To evaluate the safety and accuracy of a unilateral three‐dimensionally printed animal‐specific drill guide (3DASDG) design for unilateral stabilization in the thoracolumbar vertebral column of dogs compared to a bilateral design. Study design Cadaveric study. Sample population Fifty‐two corridors in one canine cadaver. Methods Two 3DA...
Article
Objectives To evaluate and describe brainstem auditory‐evoked response measurements in healthy African pygmy hedgehogs (Atelerix albiventris). Materials and Methods Brainstem auditory‐evoked response measurements were performed in 12 adult African pygmy hedgehogs (seven males, five females) under general anaesthesia. Waveform morphology was assess...
Chapter
"All learning is in the learner, not the teacher." Plato was right. The adage has passed the test of time and is still true in an era where technology accompanies us in not only professional but also recreational life every day, everywhere. On the other hand, the learner has evolved and so have the sources being used to satisfy curiosity and learni...
Article
Full-text available
Background Cerebrospinal fluid (CSF) lactate concentrations increase after seizure activity in many human patients independent of the underlying disease process. The effect of seizure activity on CSF lactate concentration in dogs is unknown. Hypothesis/Objectives Cerebrospinal fluid lactate concentration is unaffected by seizure activity in dogs a...
Article
Spinal subarachnoid diverticula are fluid dilations of the subarachnoid space that can cause a compressive myelopathy in dogs. These diverticula are usually associated with high motion areas in the cervical and caudal thoracic spine. The definitive etiopathogenesis has not been determined but likely involves congenital or acquired causes. Pugs, Fre...
Article
Full-text available
Background Traumatic skull fractures (TSF) are relatively frequent in dogs and cats, but little information is available regarding their clinical and imaging features. Hypothesis/Objectives To describe the neurological and computed tomographic (CT) features of a large cohort of dogs and cats with TSF. Animals Ninety‐one dogs and 95 cats with TSF...
Preprint
In Press, Journal of the American Veterinary Medical Association; 24 Apr 2020; see comments section for link to supplementary video figures. Objective: To describe a modified approach to the neurologic examination in African pygmy hedgehogs (Atelerix albiventris). Design: Descriptive study Animals: 12 adult hedgehogs (7 males, 5 females) Proc...
Article
The purpose of this study was to report the findings of clinical and genetic evaluation of a 3-month old male Boykin spaniel (the proband) that presented with progressive weakness. The puppy underwent a physical and neurological examination, serum biochemistry and complete blood cell count, electrophysiological testing, muscle biopsy and whole geno...
Article
Objective To describe the safety and feasibility of a minimally invasive spine surgery technique to access the thoracolumbar vertebral canal in dogs. Study design Prospective study. Animals Six healthy research dogs. Methods Dogs were placed under anesthesia for MRI to evaluate vertebral column and spinal cord integrity. Minimally invasive surge...
Article
Full-text available
A 2‐year‐old male domestic shorthair cat was presented for a progressive history of abnormal posture, behavior, and mentation. Menace response was absent bilaterally, and generalized tremors were identified on neurological examination. A neuroanatomical diagnosis of diffuse brain dysfunction was made. A neurodegenerative disorder was suspected. Mag...
Article
A large variety of etiologies is considered to be the cause of nerve root syndrome in dogs. Lateralized disc herniation, foraminal stenosis and malignant as well as benign nerve sheath tumors are some of the most important triggers described. The clinical signs of a nerve root syndrome are characterized by monoparesis in combination with progressiv...
Article
Full-text available
Background: Cerebrospinal fluid (CSF) lactate is frequently used as a biomarker in humans with inflammatory central nervous system (CNS) disorders including bacterial meningitis and autoimmune disorders such as multiple sclerosis. Hypothesis: Cerebrospinal fluid lactate concentrations are increased in a subset of dogs with inflammatory CNS disorder...
Article
Objective To report the successful treatment of intervertebral disc protrusion with minimally invasive microsurgery in a large breed dog. Study design Retrospective case report. Animal A 4‐year‐old, neutered male, German shepherd dog presented with chronic progressive ambulatory paraparesis and thoracolumbar pain; lumbar intervertebral disc protr...
Article
Full-text available
Neuroanatomy can be challenging to both teach and learn within the undergraduate veterinary medicine and surgery curriculum. Traditional techniques have been used for many years, but there has now been a progression to move towards alternative digital models and interactive 3D models to engage the learner. However, digital innovations in the curric...
Article
Full-text available
Background Experimental evidence shows benefit of rehabilitation after spinal cord injury (SCI) but there are limited objective data on the effect of rehabilitation on recovery of dogs after surgery for acute thoracolumbar intervertebral disc herniations (TL‐IVDH). Objective Compare the effect of basic and intensive post‐operative rehabilitation p...
Article
Full-text available
Congenital vertebral malformations (CVM) are common in brachycephalic ‘screw-tailed’ dogs; they can be associated with neurological deficits and a genetic predisposition has been suggested. The purpose of this study was to evaluate radiography as a screening method for congenital thoracic vertebral malformations in brachycephalic ‘screw-tailed’ dog...
Article
Full-text available
Background: A congenital syndrome of hearing loss and vestibular dysfunction affects Doberman Pinschers. Its inheritance pattern is suspected to be autosomal recessive and it potentially represents a spontaneous animal model of an autosomal recessive syndromic hearing loss. Hypothesis/objectives: The objectives of this study were to use whole ge...
Article
Spinal cord injury (SCI) due to acute intervertebral disc extrusions (IVDE) is common in dogs and is treated by surgical decompression. Dogs with sensorimotor complete injuries have an incomplete recovery. Pulsed electromagnetic fields (PEMF) reduce postoperative pain through anti-inflammatory effects and there is growing evidence for neuroprotecti...
Data
VIDEO 1 Neurological examination of the proband, a 12‐week‐old Doberman Pinscher affected with deafness and vestibular syndrome
Data
TABLE 1 List of private variants in the affected dog
Data
Supplementary Data 2: Rehabilitation protocol details, and feasibility scoring Basic rehabilitation protocol
Article
Between January 2006 and June 2016, 96 ruminants with neurological signs were donated to the Scottish Centre for Production Animal Health and Food Safety (SCPAHFS), University of Glasgow, by veterinarians in the field representing 5.4 per cent of all submissions. Forty-seven different neurological presenting signs were reported with 79 per cent of...
Article
In humans, abnormalities of the vertebral venous system are considered rare but significant causes of radiculopathy and myelopathy. Published information on abnormalities of the canine vertebral venous system is currently lacking. Aims of this retrospective descriptive study were to characterize magnetic resonance imaging (MRI) abnormalities of the...
Article
A six-month-old entire male dogue de Bordeaux weighing 39·5 kg was referred for evaluation of intermittent neck pain and an abnormal “clicking” noise at the cranio-cervical junction at three weeks after being kicked in the head by a horse. Clinical and neurological examination only identified hyperaesthesia on palpation and manipulation of the neck...
Article
Full-text available
Current methods used to communicate and present the complex arrangement of vasculature related to the brain and spinal cord is limited in undergraduate veterinary neuroanatomy training. Traditionally it is taught with 2-dimensional (2D) diagrams, photographs and medical imaging scans which show a fixed viewpoint. 2D representations of 3-dimensional...
Article
Full-text available
Background: The term meningoencephalocele (MEC) describes a herniation of cerebral tissue and meninges through a defect in the cranium, whereas a meningocele (MC) is a herniation of the meninges alone. Hypothesis/objectives: To describe the clinical features, magnetic resonance imaging (MRI) characteristics, and outcomes of dogs with cranial MC...
Data
Figure S2. Box‐and‐whisker plot diagram representing the subjective grading of MEC compared with ratio between MEC volume and intracalvarial brain volume in dogs with intranasal MEC.
Data
Table S4. Results of CSF analysis in dogs with abnormal CSF examination.
Data
Table S5b. Treatment and outcome of dogs with parietal/frontal MC/MEC and with concurrent intranasal and parietal MC/MEC.
Data
Figure S1. Three‐dimensional reconstruction of the intracalvarial brain (purple) and intranasal meningoencephalocele (green) based on transverse, sagittal and dorsal T2‐weighted magnetic resonance imaging sequences.
Data
Table S1. Overview of the signalment, presenting complaint and diagnosis for all cases of MC/MEC.
Data
Table S3. MRI findings in dogs with meningocele and meningoencephalocele (Case 22 is mentioned twice as it had an intranasal MEC and a parietal MC).
Data
Table S2a. Neurological signs and localization of intranasal (ethmoidal and frontal) MEC after MRI.
Data
Table S2b. Neurological signs and localization of parietal/frontal MC/MEC.
Data
Table S5a. Treatment and outcome of dogs with intranasal (ethmoidal and frontal) MEC (case 22 excluded based on the concurrent parietal MC).
Article
A seven-year-old crossbred dog presented with chronic, progressive left unilateral masticatory muscle atrophy. The neurolocalisation was to the left mandibular branch of the trigeminal nerve. MRI identified thickening of the left trigeminal nerve root, which was isointense to grey matter on T1-weighted and T2-weighted images and displayed contrast...
Article
An 8-year-old domestic short-haired cat was presented with anorexia, lethargy, ataxia and one episode of consciousness loss. A midline vertically orientated, biconcave, extra-axial mass originating from the basioccipital bone was detected on magnetic resonance images of the head. The mass was T1W iso- to hypointense when compared with normal grey m...
Article
Full-text available
Case summary A 6-month-old female domestic shorthair cat was presented with acute onset non-ambulatory right hemiparesis and horizontal nystagmus following an injection attempt in the neck, during which the cat did not cooperate. Magnetic resonance imaging (MRI) revealed a well-defined intra-axial lesion on the right side of the myelencephalon. The...
Article
Atlantoaxial subluxation was first reported in dogs nearly fifty years ago. Since that time a better understanding of the aetiologies predisposing to joint laxity and instability has been achieved. Surgeons however are still trying to address the problems associated with stabilizing this joint which by nature is often required in small juvenile dog...
Article
Full-text available
The objectives of this study were: To investigate computer-assisted digital radiographic measurement of Cobb angles in dogs with congenital thoracic vertebral malformations, to determine its intra- and inter-observer reliability and its association with the presence of neurological deficits. Medical records were reviewed (2009-2013) to identify bra...
Article
In February 2013, a flock of 20 pastured ewes was treated with oral closantel. Within 10 days of dosing, one 2-year-old Texel-cross ewe that was approximately three months in lamb was noticed to be spending a prolonged time in recumbency. On the 6th of March, the animal was referred to Scottish Centre for Production Animal Health and Food Safety (S...
Article
In people, abnormalities in vertebral column conformation, such as kyphoscoliosis, induce degenerative changes in adjacent intervertebral disc (IVD) structure and composition. It was hypothesised that canine IVDs adjacent to a vertebral malformation undergo early degeneration. In a blinded retrospective study, thoracic IVD degeneration was evaluate...
Article
Congenital vertebral malformations are common in brachycephalic “screw-tailed” dog breeds such as French bulldogs, English bulldogs, Boston terriers, and pugs. The aim of this retrospective study was to determine whether a radiographic classification scheme developed for use in humans would be feasible for use in these dog breeds. Inclusion criteri...
Article
Full-text available
Idiopathic head tremor (IHT) syndrome is a recognized but poorly characterized movement disorder in English bulldogs (EBs). The data analyzed were collected via a detailed online questionnaire and video recordings. Thirty-eight percent of the population demonstrated IHT. The first presentation was early in life. There was no sex or neutered status...
Article
Cavernous sinus syndrome is characterised by internal and external ophthalmoplegia and sensory deficits over the head due to combined deficits of the three cranial nerves (CNs) responsible for the eye movements and pupil function (CN III, IV, VI) and at least one branch of the trigeminal nerve (CN V). It has rarely been described in cats and may oc...
Article
Objective: To identify matrix metalloproteinase (MMP)-2 and -9 in CSF from dogs with intracranial tumors. Sample: CSF from 55 dogs with intracranial tumors and 37 control dogs. Procedures: Latent and active MMP-2 and -9 were identified by use of gelatin zymography. The presence of MMPs in the CSF of dogs with intracranial tumors was compared w...

Network

Cited By

Projects

Projects (2)
Project
The main objective of this project is harnessing the power of 3D printing to improve upon the placement of implants, biopsy procedures and other aspects related to spinal and intracranial surgery in veterinary species. Specific projects thus far have included patient-specific drill guides for spinal implants and guides for brain biopsy. Our main collaborators for these projects are Ola Harrysson (Center for Additive Manufacturing and Logistics at NCSU) and Julien Guevar (University of Bern).
Project
Determine the prevalence and clinical relevance of congenital vertebral malformations in 'screw-tailed' brachycephalic dogs