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Citations since 2017
6 Research Items
February 2019 - February 2022
- PhD Student
- Study functional changes in patients with inherited retinal diseases (IRDs), mainly Retinitis Pigmentosa but also Stargardt Disease or X linked retinoschisis Our work is aimed to detect and follow evolution of IRDs but also follow evolution of a potential therapeutic treatment (like a cell or gene based therapy) I use a psychophysical procedure to isolate different photoreceptor types and therefore postreceptoral pathways linked to those photoreceptor types.
February 2019 - October 2022
Our past anecdotal evidence prompted that a longer response window (RW) in the Trivector test (Cambridge Colour Test) improved mature observers’ estimates of chromatic discrimination. Here, we systematically explored whether RW variation affects chromatic discrimination thresholds measured by the length of Protan, Deutan and Tritan vectors. We empl...
Bipolar (BPD) patients have deficits in cognition, but there are still controversies about the effects of some medications on their cognitive performance. Here, we investigated the relationship between cognition in terms of executive function, memory, and attention in both first-episode medication-naive BPD patients and BPD patients taking olanzapi...
Background and objectives: Inherited retinal diseases (IRD) like retinitis pigmentosa (RP) and Stargardt’s disease (STGD) impair retinal function to varying degrees, often leading to severe visual disability or blindness. Our project was to develop, optimize and validate tests of retinal function based on photoreceptor physiology and the mechanisms...
Purpose: The purpose of this study was to compare L-cone-driven, S-cone-driven, and rod-driven temporal contrast sensitivities (tCSs) in patients with Stargardt disease 1/fundus flavimaculatus (STGD1/FF). Methods: Fourteen patients (eight male, six female; mean age, 43.21 ± 13.18 years) with genetically confirmed STGD1/FF participated in this st...
Purpose: Inherited retinal diseases affect the L-, M-, S-cones and rods in distinct ways, which calls for new methods that enable quantification of photoreceptor-specific functions. We tested the feasibility of using the silent substitution paradigm to estimate photoreceptor-driven temporal contrast sensitivity (tCS) functions in patients with ret...
Neue Techniken zur Quantifizierung des Farbsinns bei Störungen der ZapfenfunktionNew techniques for quantification of color vision in disorders of cone function: Cambridge-Color-Test und photorezeptorspezifische zeitliche Kontrastempfindlichkeit bei Patient/Innen mit heterozygoten RP1L1- und RPGR-MutationenCambridge color test and photoreceptor-specific temporal contrast sensitivity in patients with heterozygous RP1L1 and RPGR mutations
Background Inherited retinal diseases with cone dysfunction can be accompanied by severe visual loss and a marked loss of color vision despite relatively normal fundus appearance. Autosomal dominant occult macular dystrophy (RP1L1 gene) and X‑chromosomal retinitis pigmentosa (RPGR gene, including heterozygous female carriers) are important examples...