Julian HofmannUniversity of Turku | UTU · Turku Bioscience
Julian Hofmann
Master of Science
About
7
Publications
1,000
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29
Citations
Introduction
Doctoral Researcher in the Rantakari Group
at the University of Turku, Finland
Immunologist and 3D imaging enthusiast
(he/him)
Skills and Expertise
Additional affiliations
December 2020 - October 2021
January 2020 - November 2020
Education
October 2017 - November 2020
October 2014 - October 2017
Publications
Publications (7)
Spatial information of cells in their tissue microenvironment is necessary to understand the complexity of pathophysiological processes. Volumetric imaging of cleared organs provides this information; however, current protocols are often elaborate, expensive, and organ specific. We developed a simplified, cost-effective, non-hazardous approach for...
A better understanding of cell-cell and cell-niche interactions is crucial to comprehend the complexity of inflammatory or pathophysiological scenarios such as tissue damage during viral infections, the tumour microenvironment and neuroinflammation. Optical clearing and 3D volumetric imaging of large tissue pieces or whole organs is a rapidly devel...
The pituitary gland is the central endocrine regulatory organ underneath the brain, producing and releasing a variety of hormones that coordinate major body functions. The physical location of the pituitary gland underneath the brain, though outside the protective blood-brain barrier, leads to a unique immune environment of the pituitary that has n...
Dysregulated B cell responses have been described in inflammatory-bowel disease (IBD) patients; however, the role of B cells in IBD pathology remained incompletely understood. We here described Wiskott-Aldrich Syndrome interacting protein deficient ( Wipf1 -/- ) mice as novel mouse model of spontaneous, chronic colitis modelling human IBD. Concomit...
Purpose
Radiation-induced cognitive deficits have a severe negative impact on pediatric brain tumor patients. The severity of cognitive symptoms is related to the age of the child when radiation was applied, with the most severe effects seen in the youngest. Previous studies using whole-brain irradiation (WBRT) in mice confirmed these findings. To...
