Julia Khriguian

Hôpital Maisonneuve-Rosemont | HMR

Head and neck cancers constitute a heterogeneous group of tumors with varying behaviors. Treatment of these tumors is complex and often involves high doses of radiotherapy delivered to an anatomically constrained area with many nearby organs at risk. Consequently, treatments are often quite toxic. MR-Linac (MRL) radiotherapy offers the potential to...

BACKGROUND The identification of objective pain biomarkers can contribute to an improved understanding of pain, as well as its prognosis and better management. Hence, it has the potential to improve the quality of life of cancer patients. Artificial intelligence can aid in the extraction of objective pain biomarkers for cancer patients with bone me...

Background The identification of objective pain biomarkers can contribute to an improved understanding of pain, as well as its prognosis and better management. Hence, it has the potential to improve the quality of life of patients with cancer. Artificial intelligence can aid in the extraction of objective pain biomarkers for patients with cancer wi...

Radiomics-based machine learning classifers have shown potential for detecting bone metastases (BM) and for evaluating BM response to radiotherapy (RT). However, current radiomics models require large datasets of images with expert-segmented 3D regions of interest (ROIs). Full ROI segmentation is time consuming and oncologists often outline just...

Background The optimal treatment of adult craniopharyngioma (CP) remains controversial. Although benign, these tumors tend to recur locally. The choice between gross total resection (GTR) versus subtotal resection (STR) with adjuvant or delayed radiotherapy (RT) is debated. The objective of this study is to review our experience with adult CPs over...

Radiomics-based machine learning classifiers have shown potential for detecting bone metastases (BM) and for evaluating BM response to radiotherapy (RT). However, current radiomics pipelines require large datasets of images with expert-segmented 3D regions of interest (ROIs). Full ROI segmentation is time consuming and oncologists often outline jus...

Purpose: Urothelial carcinomas (UC), also known as transitional cell carcinomas, account for the majority of upper urinary tract tumors. The gold-standard therapy for operable patients with localized disease is radical nephroureterectomy. However, some patients are not surgical candidates. Data on the use of modern radiotherapy (RT) for upper urin...

Objective The majority of cancer patients suffer from severe pain at the advanced stage of their illness. In most cases, cancer pain is underestimated by clinical staff and is not properly managed until it reaches a critical stage. Therefore, detecting and addressing cancer pain early can potentially improve the quality of life of cancer patients....

Purpose: Long-term androgen deprivation therapy (LT-ADT) has been associated with decreased bone mineral density (BMD) in men with prostate cancer (PCa). Some evidence suggests that there is no impact on fracture risk despite this BMD loss. Our study aimed to quantify changes in BMD in men with high risk PCa on LT-ADT and calcium and vitamin D sup...

Purpose or objective Management of oncologic emergencies becomes critical at the start of the second year of a radiation oncology residency. Considering the limited exposure to oncology in the medical school curriculum, this knowledge gap needs to be filled prior to managing real patients. The aim of this project was to create virtual patients (VPs...

Background: To prevent postoperative thrombosis, indications for anticoagulation in finger replantation have been described, but no consensus has yet been found for cessation protocols. The aim of this study is to investigate cessation methods of intravenous anticoagulation after finger replantation. Methods: A retrospective review of all patien...

Objectives: Ureterocele management is considered to be one of the famous debates in pediatric urology. Despite some considering transurethral ureterocele incision (TUI) as a temporary line of treatment, others have reported good results in terms of being a definitive treatment. The present study evaluated the feasibility of TUI as a definitive lin...