Julia Fine

University of California, Davis | UCD · USDA-ARS

Honey bee (Apis mellifera) colonies depend on the reproductive output of their queens, which in turn is contingent on the care provided by worker bees. Viral infections in queens can compromise reproductive output, while worker infections can inhibit the successful functioning of a colony and its ability to care for the queen. Transgenerational imm...

With their long lives and extreme reproductive output, social insect queens have escaped the classic trade-off between fecundity and lifespan, but evidence for a trade-off between fecundity and immunity has been inconclusive. This is in part because pathogenic effects are seldom decoupled from effects of immune induction. We conducted parallel, bli...

With their long lives and extreme reproductive output, social insect queens have escaped the classic trade-off between fecundity and lifespan but evidence for a trade-off between fecundity and immunity has been inconclusive. This is in part because pathogenic effects are seldom decoupled from effects of immune induction. We conducted parallel, blin...

Division of labor within a honey bee colony creates a codependence between bees performing different tasks. The most obvious example of this is between the reproductive queen and worker bees. Queen bees lay 1,000 or more eggs a day, while young worker bees tend and feed queens. Young workers and queens can be exposed to pesticides when foragers ret...

Trisiloxane surfactants are often applied in formulated adjuvant products to blooming crops including almonds, exposing the managed honey bees ( Apis mellifera ) used for pollination of these crops and persisting in colony matrices like bee bread. Despite this, little is known regarding the effects of trisiloxane surfactants on important aspects of...

Pesticide exposure and queen loss are considered to be major causes of honey bee colony mortality, yet little is known regarding the effects of regularly encountered agrochemicals on honey bee reproduction. Here, we present the results of a two-generational study using specialized cages to expose queens to commonly used insect growth disrupting pes...

Global pollinator declines threaten food production and natural ecosystems. The drivers of declines are complicated and driven by numerous factors such as pesticide use, loss of habitat, rising pathogens due to commercial bee keeping and climate change. Halting and reversing pollinator declines will require a multidisciplinary approach and internat...

Honey bees (Apis mellifera) are one of the most important pollinating species of flowering plants. Recently, populations of honey bees have been declining due to a combination of factors, including the widespread use of agricultural pesticides. Laboratory studies were conducted to determine the acute oral toxicity of different formulated pesticides...

Techniques to monitor honey bee (Apis mellifera) egg production in cages allow researchers to study how different environmental factors contribute to reproduction. However, although the conditions required to facilitate queen egg production in a laboratory setting have been established, limited work has addressed the requirements for stimulating an...

As social insects, honey bees (Apis mellifera) rely on the coordinated performance of various behaviors to ensure that the needs of the colony are met. One of the most critical of these behaviors is the feeding and care of egg laying honey bee queens by non-fecund female worker attendants. These behaviors are crucial to honey bee reproduction and a...

Honey bees are valued pollinators of agricultural crops, and heavy losses reported by beekeepers have spurred efforts to identify causes. As social insects, threats to honey bees should be assessed by evaluating the effects of stress on the long-term health and productivity of the entire colony. Insect growth disruptors are a class of pesticides en...

Honey bees (Apis mellifera) are one of the most important pollinating species of flowering plants. Recently, populations of honey bees have been declining due to a combination of factors, including the widespread use of agricultural pesticides. Laboratory studies were conducted to determine the acute oral toxicity of different formulated pesticides...

Honey bees (Apis mellifera) are highly valued pollinators that help to ensure national food security in the United States, but reports of heavy annual losses to managed colonies have caused concerns and prompted investigations into the causes of colony losses. One factor that can negatively affect honey bee health and survival is agrochemical expos...

Honey bee populations have been declining precipitously over the past decade, and multiple causative factors have been identified. Recent research indicates that these frequently co-occurring stressors interact, often in unpredictable ways, therefore it has become important to develop robust methods to assess their effects both in isolation and in...

Bee bread collection. (DOCX)

Average eggs laid per day, maximum eggs laid per day, and laying vs. non-laying queens by experiment and treatment. (DOCX)

Owing to the recent declines in honey bee (Apis mellifera L.) populations, there is a need for field and laboratory studies to investigate threats to pollinator health. This study examines the hypothesis that the organophosphate alternative, Rimon 0.83EC, can have consequences to honey bee health by combining newly acquired field residue data, labo...

In chronic feeding assays, the common agrochemical inert formulant, N-methyl-2-pyrrolidone (NMP) is at least 20 times more toxic to honey bee larvae than to adults, but the underlying cause of this difference is unknown. In other taxa, NMP is primarily detoxified via a cytochrome P450 mediated pathway. Using a LC-MS method, putative cytochrome P450...

Organosilicon surfactants are the most potent adjuvants available for formulating and applying agricultural pesticides and fertilizers, household cleaning and personal care products, dental impressions and medicines. Risk assessment of pesticides, drugs or personal care products that takes into account only active ingredients without the other form...

Honey bees are highly valued for their pollination services in agricultural settings, and recent declines in managed populations have caused concern. Colony losses following a major pollination event in the United States, almond pollination, have been characterized by brood mortality with specific symptoms, followed by eventual colony loss weeks la...

Agrochemical risk assessment that takes into account only pesticide active ingredients without the spray adjuvants commonly used in their application will miss important toxicity outcomes detrimental to non-target species, including humans. Lack of disclosure of adjuvant and formulation ingredients coupled with a lack of adequate analytical methods...

Dr. Fumio Matsumura's legacy embraced a passion for exploring environmental impacts of agrochemicals on non-target species such as bees. Why most formulations are more toxic to bees than respective active ingredients and how pesticides interact to cause pollinator decline cannot be answered without understanding the prevailing environmental chemica...