Jukka Pekka Matinlinna

The University of Hong Kong | HKU · Faculty of Dentistry

In-office bleaching, using hydrogen peroxide, is effective to remove dental enamel stains. However, bleaching agents can deteriorate surface properties of CAD-CAM materials. This in vitro study aimed to investigate the effect of in-office bleaching agents on Vickers hardness and surface topography of polished and unpolished dental CAD-CAM composite...

Background: One of the crucial factors influencing the longevity of anterior aesthetic dental restorations is the colour stability of resin composites. Bleaching and whitening have become popular methods for enhancing dental aesthetics. Home whitening techniques, such as special pens, are widely available commercially. This in vitro study aimed to...

Poly (methyl methacrylate) (PMMA), is an acrylic polymer substance that is mostly used for denture base applications. The purpose of this laboratory study was to investigate the effect of adding 0.05 wt.% Ag-doped carbon nanotubes (CNT) to PMMA-based (PMMA and MMA) denture base material on the impact strength, microhardness, and antimicrobial activ...

Purpose To compare and contrast mechanical properties of experimental alkali-resistant (AR) glass fibre-reinforced composites (FRCs) silanised with one of three functional trialkoxysilanes: 3-methacryloxypropyltrimethoxysilane (3-MPS), 8-methacryloxypropyltrimethoxysilane (8-MOS) and 3-acryloxypropyltrimethoxysilane (3-APS). The experimental AR-FRC...

The presence of Si on the Ti surface is quintessential for a strong, durable silane‐based adhesion utilized in several dental applications. Silica‐coating and silanization form durable ≡Si‐O‐Si≡ bonds, which might have a positive effect on resin‐Ti adhesion. This laboratory study studied the effect of strong acids, their blends, and silica‐coating...

Background: The ability of cancer cells to be invasive and metastasize depend on several factors, of which the action of protease activity takes center stage in disease progression. Purpose/objective: To analyze function of new K21 molecule in the invasive process of oral squamous cell carcinoma (OSCC) cell line. Materials & methods: The Fusob...

Purpose To compare and contrast mechanical properties of experimental alkali-resistant (AR) glass fibre-reinforced composites (FRCs) silanised with one of three functional trialkoxy silanes: 3-methacryloxypropyltrimethoxysilane (3-MPS), 8-methacryloxypropyltrimethoxysilane (8-MOS) and 3-acryloxypropyltrimethoxysilane (3-APS). The experimental AR-FR...

Durable adhesion between resin composite cement and Ti prostheses is critical for a long clinical life. A rough surface is a prerequisite for mechanical interlocking and silica-coating followed by silanation for chemical adhesion. Commercially pure grade-2 Ti specimens were modified by silica-coating and silanized with an experimental silane blend...

Purpose To investigate mechanical properties of experimental resin composites containing 8-methacryloxyoctyltrimethoxysilane (MOS) and a more commonly used silane monomer, 3-methacryloxypropyltrimethoxysilane (MPS). Materials and methods MOS and MPS were hydrolysed in 95vol% ethanol solution at pH 4 for 1 h before silanisation of SiO2-based bioact...

Quaternary ammonium compounds (QACs) have been widely used due to their excellent antimicrobial activity. However, using the technology where nanomaterials are employed as drug carriers to deliver QAC drugs has not been fully explored. In this study, mesoporous silica nanoparticles (MSNs) with short rod morphology were synthesized in a one-pot reac...

Purpose To investigate mechanical properties of experimental resin composites contain 8-methacryloxyoctyltrimethoxysilane (MOS) and a commonly used silane, 3-methacryloxypropyltrimethoxysilane (MPS). Materials and methods MOS and MPS were hydrolysed in 95vol% ethanol solution at pH 4 for 1h before silanisation of SiO2-based bioactive glass powder...

Artificial Intelligence (AI) is the ability of machines to perform tasks that normally require human intelligence. AI is not a new term, the concept of AI can be dated back to 1950. However, it has not become a practical tool until two decades ago. Owing to the rapid development of three cornerstones of current AI technology—big data (coming throug...

Objectives: This study utilised an Artificial Intelligence (AI) method, namely 3D-Deep Convolutional Generative Adversarial Network (3D-DCGAN), which is one of the true 3D machine learning methods, as an automatic algorithm to design a dental crown. Methods: Six hundred sets of digital casts containing mandibular second premolars and their adjac...

The purpose of this study was to investigate the diagnostic accuracy of CBCT for the detection of accessory mental foramina (AMFs) in dry mandibles using two different devices and three different CBCT imaging modalities. A total of 40 dry mandibles were selected to generate corresponding CBCT images, each with three different CBCT imaging modalitie...

This review aims to provide a comprehensive analysis of the characterizations of bioactive glass (BAG)-loaded dental resin-based composite materials. Online databases (Web of Science, PubMed, and Science Direct) were used to collect data published from January 2011 to January 2022. Only BAG-containing resin adhesive and resin restorative composites...

Background The design of biological active and antibacterial implant coating remains a challenging topic to ensure early implant fixation and to prevent peri-implantitis. In this laboratory work, we reported a newly designed antibacterial porous calcium phosphate (CP) bilayer functional coating on titanium implant incorporated with molybdenum triox...

Purpose: Measurement of bacterial adhesion has been of great interest for different dental materials. Various methods have been used for bacterial counting; however, they are all indirect measurements with estimated results and therefore cannot truly reflect the adhesion status. This study provides a new direct measurement approach by using a simpl...

3D Printing has become the go-to term when newer advances in medical and dental healthcare sectors are discussed in any manner. The term has become associated with futuristic technology which will revolutionise the medical and dental healthcare industry. 3D printing, however, has been functional since the 1980s, hitherto known as rapid prototyping,...

Objectives To evaluate the biocompatibility and mechanical properties of experimental bis-phenol-A and bis-GMA free E-glass fiber-reinforced composites (FRCs) prepared with hexanediol dimethacrylate (HDDMA) based resin. Methods Two ratios of HDDMA/TEGDMA resin were evaluated: exp-1 (70/30 wt.%) and exp-2 (50/50 wt.%) with two bis-GMA resin control...

Abstract: This laboratory study aimed to compare, contrast, and evaluate the effect of a novel dual surface modification method on the adhesion strength of resin composite cement to titanium. C.p.-2 grade titanium samples were silica-coated, etched with HNO3(69vol %) or a blend of HCl (35vol %) and H3PO4 (85vol %), for 1 h at 80ᵒC. Surface roughnes...

Purpose: This study explores novel solutions other than standard SBF for biomimetic evaluations of mineralization particularly for resin composites containing bioactive glass (BAG). Methods: Experimental UDMA/TEGDMA resin composites with 0.0, 1.9, 3.8 or 7.7 vol% of 45S5 BAG fillers were prepared. Besides simulated body fluid (SBF) as control, t...

Endodontics (derived from the Greek words endo – “inside” and odont – “tooth”) is the speciality of dentistry that focuses on the dental pulp tissues. The dental pulp can be diseased due to dental caries, trauma, or ascending infections from the periodontal tissues.

Purpose/Aim This study aims at explores immersion solutions other than standard SBF that could evaluate mineralization of dental resin composites containing low percentage bioactive glass (BAG). Materials and Methods Experimental UDMA/TEGDMA resin composites containing total 25 vol% glass fillers (with 0.0, 1.9, 3.8 or 7.7 vol% of 45S5 bioactive g...

The study was performed to have chairside identification of specific biomarkers for diagnosing periodontal disease in diabetic patients at a very early stage using spectroscopic probe design and parameters. Patients were divided into groups: Group (A) - healthy patients, Group (B) - patients with type 2 Diabetes Mellitus (DM) without chronic period...

The present dry-mandible study evaluated the presence of the mental (MF), lingual (LF), and retromolar (RMF) foramina to assess the accuracy of CBCT in detecting these anatomical structures. In total, 38 human dry mandibles were analyzed (30 men, 8 women; mean age: 61.9 ± 13.7 years). CBCT scans were taken using low-dose parameters, and LF, MF, and...

Fusobacterium nucleatum (F. nucleatum) is a gram-negative obligate anaerobe bacterium that threatens human periodontal health. It can cause many oral diseases, including periodontitis, gingivitis and peri-implantitis, and even some diseases such as colorectal cancer are related to it. This paper aims to develop a novel and simple surface modificati...

Objective: The aim of this study was to investigate and evaluate the self- reported oral health knowledge, attitude and practice among university students in Myanmar. It was also aimed to provide the data essentials to planning, implementation, evaluation of the services for the prevention, control, treatment and to set up priorities among those se...

Abstract: Guided tissue regeneration (GTR) membranes are used for treating chronic periodontal lesions with the aim of regenerating lost periodontal attachment. Spatially designed functionally graded bioactive membranes with surface core layers have been proposed as the next generation of GTR membranes. Composite formulations of biopolymer and bioc...

Enterococcus faecalis as an important nosocomial pathogen is critically implicated in the pathogenesis of endocarditis, urinary tract, and persistent root canal infections. Its major virulence attributes (biofilm formation, production of proteases, and hemolytic toxins) enable it to cause extensive host tissue damage. With the alarming increase in...

The aim of the study is to investigate a new formulation, based on dioctadecyldimethyl ammonium-bromide (QA) and riboflavin (RF), combining antimicrobial activities and protease inhibitory properties with collagen crosslinking without interference to bonding capabilities in a rabbit model. Quaternary ammonium riboflavin (QARF) experimental adhesive...

Despite the widespread observations on the osteogenic effects of magnesium ion (Mg ²⁺ ), the diverse roles of Mg ²⁺ during bone healing have not been systematically dissected. Here, we reveal a previously unknown, biphasic mode of action of Mg ²⁺ in bone repair. During the early inflammation phase, Mg ²⁺ contributes to an upregulated expression of...

The purpose of the study was to measure the cement thickness obtained when ceramic rods were luted to dentin and to analyze the relation between cement thickness and the previously published tensile bond strength of similar test specimens. In addition, the ISO standard 4049:2019 method was used to determine the film thickness of the used cements. Z...

Enterococcus faecalis as an important nosocomial pathogen is critically implicated in the pathogenesis of endocarditis, urinary tract and surgical wound infections. Its major virulence attributes (biofilm formation, production of proteases and hemolytic toxins) enable it to cause extensive host tissue damage. With the alarming increase in enterococ...

Purpose: Fiber-reinforced composites (FRCs) have received considerable attention, owing to their potential use in dental prostheses or bone fracture fixation applications. The aim of this systematic review was to analyze and report the biological properties of FRCs reported in the existing literature. Study selections: A systematic search of four d...

Objective The effects of saliva on demineralized dentin and silver diamine fluoride (SDF) were investigated in vitro. Methods Dentin samples stored in deionized water (DIW), buffer solution (BS), basal medium mucin (BMM), and unstimulated whole saliva (UWS) were demineralized for 3 days and immersed in the same storage media. SDF as a 38 mass% sol...

Purpose Fiber-reinforced composites (FRCs) have received considerable attention, owing to their potential use in dental prostheses or bone fracture fixation applications. The aim of this systematic review was to analyze and report the biological properties of FRCs reported in the existing literature. Study selections A systematic search of four dat...

Objectives: The objectives of the study were (1) to develop a novel multi-element-doped porous 58S bioactive glass coating for titanium implants and (2) to investigate the physiochemical, cell cytotoxic and antibacterial properties of this novel coating for titanium implants. Methods: This study employed the sol-gel method to develop a silver-,...

Objective This literature research aimed to compare, contrast and quantify the innovations in the most commonly used dental biomaterials. Methodology Original research articles based on experimental dental biomaterials published between 2007 and 2019 were retrieved and reviewed. A search of electronic databases, PubMed, Scopus, and Web of Science...

Objective Proteolytic and demineralizing agents have a profound influence on the dentin ultrastructure, which plays a key role in the mechanical integrity of the tooth and integrity of dentin-biomaterial interfaces. In-depth characterization of dentin treated with a novel root canal irrigation protocol comprising sodium hypochlorite (NaOCl) and eti...

The objective of this study is to evaluate the effect of an experimental adhesive silane blend system in achieving optimal orthodontic bonding to zirconia surfaces. Also, the effect of the sandblasting distance on the adhesion strength and surface roughness of the zirconia bonding surface was determined. A total of 180 zirconia specimens were used...

Objectives: To use both absolute anteroposterior maxillary complex length (APMCL) and relative APMCL to investigate the relationship between the maxillary complex, its individual bony segments, and their association to the anterior cranial base. In addition, the relationship between length and position of the maxillary complex was analyzed. Materia...

Purpose: To seek a simple solution that can recycle and regenerate dental CAD/CAM zirconia green blanks from its waste residuals. Methods: Waste residuals (3M® Lava™ Plus HT) were pulverized after dry milling and cutting, and subsequently sieved before pickling in a 0.5 M nitric acid. These powders were then dry-pressed and pre-sintered into blo...

Technological advances have made it possible to examine dental resin composites using 3D nanometer resolution. this investigation aims to characterize existing dental nano-hybrid and micro-hybrid resin composites through comparing and contrasting nano-computed tomography (nano-ct) with micro-ct and high-resolution SeM images. eight commercially ava...

Objective: To investigate the effect of blue light photoactivated riboflavin modified universal adhesives on dentin collagen biodegradation resistance, dentin apparent elastic modulus, and resin-dentin bond strength with interfacial morphology. Methods: Dentin slabs were treated with 0.1% riboflavin-5-phosphate modified (powder added slowly whil...

Objectives: Evaluate a new modified quaternary ammonium silane irrigant solution for its antimicrobial, cytotoxic and mechanical properties of dentine substrate. Methods: Root canal preparation was performed using stainless steel K-files™ and F4 size protaper with irrigation protocols of 6% NaOCl + 2% CHX; 3.5% QIS; 2% QIS and sterile saline. Bi...

Purpose: To test the hypothesis that surface roughening and polishing of ceramics have no effect on their surface roughness and biofilm adhesion. Materials and methods: Feldspathic ceramic Vitablocks™ TriLuxe forte (VTF), lithium disilicate glass IPS e.max Press™ (IPS) and zirconia reinforced lithium silicate Vita Suprinity™ (VS) ceramic blocks...

Enterococcus faecalis is a biofilm-forming, nosocomial pathogen that is frequently isolated from failed root canal treatments. Contemporary root canal disinfectants are ineffective in eliminating these biofilms and preventing reinfection. As a result, there is a pressing need to identify novel and safe antibiofilm molecules. The effect of short-ter...

Enterococcus faecalis is a biofilm-forming, nosocomial pathogen that is frequently isolated from failed root canal treatments. Contemporary root canal disinfectants are ineffective in eliminating these biofilms and preventing reinfection. As a result, there is a pressing need to identify novel and safe antibiofilm molecules. The effect of short-ter...

To study the antimicrobial effects of quaternary ammonium silane (QAS) exposure on Streptococcus mutans and Lactobacillus acidophilus bacterial biofilms at different concentrations. Streptococcus mutans and Lactobacillus acidophilus biofilms were cultured on dentine disks, and incubated for bacterial adhesion for 3-days. Disks were treated with dis...

This aim was to assess the biomechanical and biocompatibility properties of novel glass fibre-reinforced composites (FRCs) with a fluorinated urethane dimethacrylate (FUDMA) resin. Three ratios of FUDMA/TEGDMA (30/70 wt%, 50/50 wt%, 70/30 wt%) and two ratios of control FRCs with bis-GMA/TEGDMA (50/50 wt% and 70/30 wt%) containing long silanized E-g...

Despite the vast literature on the effects of root canal irrigants on the dentin characteristics, the precise effects of clinically relevant irrigation sequences remain unclear. In this review, we systematically dissect the role of different sequential irrigation approaches that are used in clinical endodontics. Using a systematic search strategy,...

Zirconia (ZrO2) ceramic is widely used in dentistry as a clinical dental biomaterial. In this review, we are focusing on and summarizing the biological performance of zirconia under different surface characteristics. We have included an initial tissue cell attachment study on zirconia and bacterial adhesion on zirconia. Our results suggest that sur...

The use of magnesium ion (Mg2+)-modified biomaterials in bone regeneration is a promising and cost-effective therapeutic. Despite the widespread observation on the osteogenic effects of Mg2+, the diverse roles played by Mg2+ in the complex biological process of bone healing have not been systematically dissected. Here, we reveal a previously unknow...

Objectives To evaluate transesterification based dissolution of dimethacrylate and epoxy polymers, the former containing ester groups. Polymer substrates were treated with an adhesive resin (Stick™ Resin) and an organic catalyst-alcohol solution (ethylene glycol and triazabicyclodecene). The surface was chemically and nanomechanically analyzed with...

Objectives: Enterococcus faecalis is the most prevalent species isolated from failed root canal therapy. E. faecalis has also recently emerged as a life-threatening multidrug-resistant nosocomial pathogen and thus, therapeutic options for serious enterococcal infections are critical, yet limited. Selected yeasts with GRAS (Generally Recognized as S...

Zirconia has become an excellent choice of dental implants because of its excellent mechanical strength, aesthetic, and biocompatibility. Although some studies have shown ultraviolet (UV) irradiation is effective to photofunctionalize dental zirconia that can improve osteoblastic function, the scattered information has not identified the most effec...

The powered toothbrush has become a modern dental tool that is available in the supermarket. Indeed, the design of the powered toothbrush, e.g., mechanical and electrical, would affect not only the efficacy but also the safety of the products. This narrative review attempted to view the powered toothbrush from design, safety, and application points...

Titanium and its alloys are widely used in biomedical devices, e.g. implants, due to its biocompatibility and osseointegration ability. In fact, fungal (Candida spp.) infection has been identified as one of the key reasons causing the failure of the device that is inevitable and impactful to the society. Thus, this study evaluated the surface morph...

Purpose: The purpose of this study was to evaluate the effect of surface treatments on zirconia-resin bonding and the effect of aging on bond durability for one year. Method: Three hundred and twenty zirconia blocks were divided into 4 equal study groups. Group 1 (control): as-sintered, group 2: (GB): grit-blasted, group 3: (LAS): laser-etched,...

The veneers are restorations generally performed on the labial surface of aesthetically compromised anterior teeth. The tooth preparation is restricted to the removal of a small layer of the tooth surface, on the area visible during smile or conversation, conserving the proximal and lingual surfaces. The restoration can be performed directly, with...

Abstract The aim of this laboratory study was to evaluate the effect of titanium dioxide (TiO2) nanoparticles reinforced experimental adhesive resin for orthodontic bonding. The experimental resin (bis-Phenol-A free) was prepared using urethane dimethacrylate, hydroxypropyl methacrylate, camphorquinone and N, N-cyanoethyl methylaniline. TiO2 nanopa...

Reconstruction of long-bone segmental defects (LBSDs) has been one of the biggest challenges in orthopaedics. Biomaterials for the reconstruction are required to be strong, osteoinductive, osteoconductive, and allowing for fast angiogenesis, without causing any immune rejection or disease transmission. There are four main types of biomaterials incl...

Sutures are greatly involved in both normal craniofacial growth and developmental anomalies. Having clear parameters for defining their morphology is fundamental to properly investigate their physiological or pathological development. However, the current literature is lacking of well‐defined methods for the assessment of these structures. This stu...

Aim: To investigate the null hypothesis that neither the surface conditioning (collagen, serum, saliva) of HA discs, nor the biofilm age (3 days vs 21 days) have a significant effect on the cellular and matrix composition of biofilms, using Enterococcus faecalis as the model organism. Methodology: Sterile Hydroxyapatite (HA) discs were condition...

Aim:Bis-GMA has been most commonly used in dental resin composites over 40 years. Concerns have arisen with respect to the presence of the estrogen analogue, Bis-phenol A from Bis-GMA materials. Therefore, the development of new monomers is important to eliminate this concern. The aim of this study was to investigate the degree of conversion, polym...