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Publications (467)
Diet, especially the intake of dietary fibre, and weaning practices may influence pig wellbeing. This study assessed changes in salivary stress and immune markers in sows and their offspring fed either hay (HAY) or sugar beet pulp (SBP), either fine (F) or coarse (C), during gestation and lactation. The effect of weaning age (conventional-CW, late-...
Background: Methionine (Met) is a popular nutritional supplement in humans and animals. It is routinely supplemented to pigs as L-Met, DL-Met, or DL-2-hydroxy-4-(methylthio) butanoic acid (DL-HMTBA). Methods: We investigated the effect of these Met supplements on jejunal amino acid (AA) transport in male castrated Piétrain × Danbred pigs, also incl...
Dietary fibre is mainly classified according to its chemical characteristics but structure and particle size of fibre-rich feedstuff can also be decisive for digestion and performance. So far, only few studies investigated this in pigs. This experiment aimed to compare coarse and finely ground dried hemp plants and apple pomace regarding performanc...
The microbiome undoubtedly plays a major role in stabilizing health and ensuring the highest possible related resilience against environmental stressors and infections. Pigs have distinctly developed microbiomes depending on age, husbandry, and diet. Furthermore, the microbial composition in the digestive tract differs depending on the localization...
Incorporating pharmacological levels of Zn in nursery pig diets is a well-recognized practice for reducing post-weaning diarrhea, enhancing growth performance, and enhancing gut health. We hypnotized that the use of a specific form of ZnO (small aggregates and agglomerated particles; SAAP), which provides a greater antibacterial property than stand...
The swine gastrointestinal tract contains a great variety of microbes, forming a complex and dynamic ecosystem. Various internal and external factors (e.g. age, breed and diet) may influence its composition. This study aimed to investigate the gut microbial diversity of German Piétrain boars housed on different deep‐litter bedding materials (region...
Investigate the effect of Gln supplementation of suckling piglets from 1 – 11 d on pre- and post-weaning BW development, and the
immunological response to an LPS challenge at 54 d.
This study examined the effects of a 3-strain Bacillus-based probiotic (BP; Bacillus amyloliquefaciens and two Bacillus subtilis) in broiler diets with different rye levels on performance, mucus, viscosity, and nutrient digestibility. We distributed 720 one-d-old female broilers into 72 pens and designed nine diets using a 3 × 3 factorial approach,...
Breeding for higher fertility has resulted in a higher number of low birthweight (LBW) piglets. It has been shown that LBW piglets grow slower than normal birthweight (NBW) littermates. Differences in growth performance have been associated with impaired small intestinal development. In suckling and weaning piglets, glutamine (Gln) supplementation...
Reducing antibiotic use is one of the biggest challenges in pig farming, as antibiotics have been used for years to control typical problems such as newborn or post-weaning diarrhea. The pressure a one health approach has created on animal production regarding antimicrobial resistance is an opportunity to find other strategies against enterobacteri...
A 3×2 experiment was conducted to investigate the
effects of different feeding systems (FS) and castration on the
growth performance and carcass traits in lambs of Dhamari
sheep. 18 lambs were divided into 3 feeding systems with 6
lambs, 3 castrated and 3 uncastrated each. In the first FS, lambs
were stall-fed and each lamb received daily 5% dried...
Livestock production in developing countries faces several difficulties such as a general shortage of feed resources, regional availability, and quality. Climate change further exacerbates these problems, leading to a massive reduction in ruminant productivity. Therefore, there is a need for the use of adaptable and resilient forage plants that can...
The present study aimed to investigate the effect of age, breed, and sex of broilers, as well as a probiotic or phytobiotic product on mucosal morphology, bacterial metabolites, and immune traits in the ileum of broilers. A total of 2,880 one-day-old male and female broiler chicks from two breeds (Ross308® and Cobb500®) were randomly assigned to 72...
Sow colostrum has been reported to protect the IPEC-J2 cells and piglet colon tissues from detrimental effect of Clostridioides difficile toxins. Since dietary fibre can influence the colostrum composition in sows, we hypothesised that it can also differentially affect the colostrum potential against C. difficile toxin-induced effects in IPEC-J2. I...
Little is known about the animal- and diet-related factors that could interfere with the plasma zinc (Zn) concentrations of equines. Additionally, the adequacy of plasma to reflect changes in the Zn intake is unclear. In the first part of this study, the plasma Zn concentrations of hospitalized horses and ponies (n = 538) were measured and evaluate...
Beneficial effects of pro- and prebiotics in weanling piglets are of great interest in livestock production. Similarly, the use of specific vaccines is of interest as alternative to antibiotics to reduce post-weaning performance losses. The aim of this study was the assessment of the effect of a dual-strain probiotic (B. subtilis and B. licheniform...
The effects of dietary zinc on the immune function of equines have not been evaluated in detail so far. In the present study, eight healthy adult ponies and two healthy adult horses were fed a diet supplemented with either zinc chloride hydroxide or zinc methionine in six feeding periods of four weeks each (according to maintenance zinc requirement...
Dietary fiber (DF) is receiving increasing attention, and its importance in pig nutrition is now acknowledged. Although DF for pigs was frowned upon for a long time because of reductions in energy intake and digestibility of other nutrients, it has become clear that feeding DF to pigs can affect their well-being and health. This review aims to summ...
Dietary supplementation with arginine (Arg) or glutamine (Gln) has been considered as an option to improve nursing performance in reproductive sows. This study investigated whether a low-level supplementation of Arg or Gln or a blend of both could modify milk nutrients and improve piglets’ growth beyond weaning. Seventy-two multiparous sows were as...
Maternal dietary factors have been reported to influence Clostridioides difficile colonization in the offspring. Twenty suckling piglets from sows fed diets supplemented with high-fermentable sugar beet pulp (SBP) or low-fermentable lignocellulose (LNC) fibers during gestation and lactation were dissected in the first week after birth. Postmortem a...
Antibiotic resistance poses a risk for human and animal health, leading to a growing demand for effective alternatives. Combining nutritional tools and parent stock vaccination could be an approach to achieve sufficient protection against bacterial infections in poultry. In an Escherichia coli O1/O18 challenge trial, we investigated the protective...
Mortality, impaired development and metabolic dysfunctions of suckling low-birthweight piglets may be influenced by modulating the intestinal microbiome through glutamine supplementation. Therefore, this study examined whether glutamine supplementation may affect the colonic development and microbiome composition of male low- and normal-birthweight...
The cost of feed ingredients in poultry production is constantly increasing and it is one of the main constraints globally and especially in low income countries. As a consequence, scientists search for cheap and available sources of feed protein. The M. oleifera leaves have not only high protein but also excellent nutritive and biological properti...
A total of 2,880 one-day-old male and female broiler chicks from two breeds, Ross308 and Cobb500 were randomly assigned to 72 pens. Broilers were offered three diets: a wheat-soybean diet without (CO), or with either a probiotic (probiotic; 2.4 x 10⁹ CFU/kg diet of Bacillus subtilis DSM32324 and DSM32325 and B. amyloliquefaciens DSM25840) or a phyt...
Introduction: Sow-piglet association is crucial for the early microbial development and resilience to diseases in the offspring [1]. Dietary fibre has a potential to modulate gut microbiota in pigs [2]. Still little is known about the sow-piglet early microbial programming. Therefore, it was hypothesised that a maternal diet rich in either high- or...
Fast optimisation of farming practices is essential to meet environmental sustainability challenges. Hologenomics, the joint study of the genomic features of animals and the microbial communities associated with them, opens new avenues to obtain in-depth knowledge on how host-microbiota interactions affect animal performance and welfare, and in doi...
The supplementation of feed with phytases enables broilers to utilize more efficiently phosphorus (P) from phytic acid (IP6), the main storage form of P in plants. The current study evaluated the addition of 500, 1000, and 3000 FTU of phytase per kg to a phytate-containing diet with low P level (LP) fed to broilers from 1 to 21 days of age and comp...
Health and well-being of dogs are of paramount importance to their owners. Digestion plays a key role in dog health, involving physicochemical, mechanical and microbial actors. However, decades of breeding selection led to various dog sizes associated with different digestive physiology and disease sensitivity. Developing new products requires the...
Clostridioides difficile is one of the pioneer gut colonisers in pigs and ithas also been documented as a major cause of enteritis outbreaks inneonatal piglets. The sow-piglet relationship is crucial for the earlymicrobial programming in the offspring. We hypothesised that a sow’sdiet rich in either high- (SBP) or low-fermentable (LNC) fibre during...
Adequate levels of dietary fibre can reduce the risk of intestinal health disorders in rabbits after weaning. Therefore, it was the aim of the study to investigate the impact of different lignocellulose and cellulose addition to rabbits' diets on performance and intestinal traits in lactating does and weaned rabbits. A total of 60 rabbit does (4.41...
An increasing world population along with increasing human needs have raised demand for animal origin products. Moreover, high prices of conventional animal feeds have led to a demand for alternative feedstuff. Food waste can be an alternative feed ingredient. The aim of the present study was to investigate the effect of dietary inclusion of dried...
Feeding high-energy (HED) or high-fat diets during gestation and lactation to pigs may help cover the energy requirements of high-prolific sows but may also adversely affect their reproductive performance. The microalga Arthrospira plantensis (Sp), rich in bioactive compounds, has been described to exert beneficial health effects. The present study...
Dietary fiber has a potential to modulate the gut microbiota in sows. We hypothesized that a maternal diet rich in either high- or low-fermentable fiber during gestation and lactation influences Clostridioides difficile gut colonization in suckling piglets. Twenty sows were fed gestation and lactation diets enriched with either high-fermentable sug...
Background
It has been shown that small intestine development in low birth weight (LBW) piglets is impaired. Glutamine (Gln) has been reported to improve piglet health and intestinal function in weaned piglets, but data is scarce in suckling piglets. This study was conducted to investigate the effects of oral Gln supplementation compared to Alanine...
Methionine (Met) as an essential amino acid has key importance in a variety of metabolic pathways. This study investigated the influence of three dietary Met supplements (0.21% L-Met, 0.21% DL-Met and 0.31% DL-2-hydroxy-4-(methylthio)butanoic acid (DL-HMTBA)) on the metabolome and inflammatory status in the small intestine of pigs. Epithelia from d...
The large quantities of food waste that are generated every year have raised management concerns. Animal diets might be a feasible strategy for utilizing food waste and partially replacing commercially available feedstuffs. The present study examined the potential use of food waste originating from hotels for broiler chickens’ diets. Two hundred an...
Numerous bioactive plant additives have shown various positive effects in pigs and chickens. The demand for feed additives of natural origin has increased rapidly in recent years to support the health of farm animals and thus minimize the need for antibiotics and other drugs. Although only in vivo experiments can fully represent their effect on the...
Low birthweight (LBW) neonates show impaired growth compared with normal birthweight (NBW) neonates. Glutamine supplementation benefits growth of weaning piglets, while the effect on newborn piglets is not sufficiently clear. We examined the effect of early neonatal glutamine supplementation on piglet growth, milk intake, and metabolic parameters....
Objectives
From the authors’ experience, the consumption of a balanced prescription home-prepared diet that includes zucchini (courgette) benefits cats with recurrent urolithiasis, but there is no published evidence to support this. The aim was to study the effects on urinary parameters of (1) a balanced prescription home-prepared diet containing z...
Feline diets can markedly differ in their protein concentration and quality, which might also affect the intestinal microbiota of cats. In the present study, 6 canned diets, differing in their protein quality (high/low, achieved by varying amounts of meat and collagen-rich ingredients) and concentration (high quality/low quality: 36.2/36.7% in dry...
Dogs occupy a full place in the family and their well-being is of paramount importance to their owners. Digestion, a complex process involving physicochemical, mechanical, and microbial parameters, plays a central in maintaining animals healthy. As in vivo studies in dogs are more and more restricted by ethical, regulatory, societal, and cost reaso...
Due to the global spread of antibiotic resistance, there is a strong demand to replace antimicrobial growth promotors in livestock. To identify suitable additives that inhibit the growth of avian pathogenic Escherichia coli O1/O18 and Salmonella enterica serotype Enteritidis strains, an ex vivo screening was performed. Inulin and fructooligosacchar...
This study aimed to investigate the effect of fiber-rich rye and rapeseed meal (RSM)
compared to wheat and soybean meal (SBM) on fiber digestibility and the composition and metabolic activity of intestinal microbiota. At weaning, 88 piglets were allocated to four feeding groups: wheat/SBM, wheat/RSM, rye/SBM, and rye/RSM. Dietary inclusion level was...
Extensive research in recent years into the use of various fiber sources in poultry nutrition has led to the perception that dietary fiber is more than a simple diet diluent. Several studies showed that the feeding of insoluble fiber sources such as oat hulls, sunflower hulls or wood shavings may affect digestive physiology and function improving c...
Background
Given the key role of methionine (Met) in biological processes like protein translation, methylation, and antioxidant defense, inadequate Met supply can limit performance. This study investigated the effect of different dietary Met sources on the expression profile of various Met transporters along the gastrointestinal tract (GIT) of pig...
Immunomodulation of airway hyperreactivity by excretory-secretory (ES) products of the first larval stage (L1) of the gastrointestinal nematode Trichuris suis is reported by us and others. Here, we aimed to identify the proteins accounting for the modulatory effects of the T. suis L1 ES proteins and studied six selected T. suis L1 proteins for thei...
The present study evaluated effects of fermentation with or without enzymes (phytase, pectinase and β-glucanase) on the nutritional quality of rapeseed cake (RSC). The impact on growth performance and nutrient digestibility in broilers as a consequence of substituting soybean meal (SBM) in the diet with fermented RSC was also investigated. A standa...
Zinc supplements are often used in equine nutrition to support skin and hoof quality or the immune function. However, no data on the effects of dietary zinc on the intestinal microbiota of horses and ponies are available so far. In the present study, varying dietary zinc concentrations (maintenance (4 mg/kg BW0.75/day), 120 mg/kg dry matter (DM)/da...
The potential use of food residues for pet food could significantly contribute to food waste reduction. In the present study, the effects of the inclusion of dried food residues (DFR) (0, 5, 10 and 15%) in a complete diet were evaluated in seven healthy adult cats. At the end of each three-week feeding period, feces were collected. The analysis of...
Supplementation of pharmacological levels of ZnO (3000 ppm) is widely used for prevention and treatment of diarrhea in weaning piglets and to improve their performance. However, this practice has raised concerns about environmental impact, antimicrobial resistance and nutritional interactions. In this study we compared graded amounts of regular ZnO...
Urinary tract infections influence the mortality rate in pigs and are linked to extensive antibiotic usage in the farm industry. Filipendula ulmaria (L.) Maxim. and Orthosiphon aristatus (Blume) Miq. are widespread medicinal plants traditionally used to treat urinary tract disorders. As their preparations are orally administered, the metabolism of...
Segmented filamentous bacteria (SFB) are present in various animal species including pigs. The aim of this work was to analyze the occurrence of SFB in different parts of the gastrointestinal tract of piglets of different ages. A total of 377 DNA extracts from stomach, jejunum, ileum, cecum and colon digesta, and from feces collected on different t...
Rye and rapeseed meal (RSM) are alternatives to wheat and soybean meal (SBM) in pig nutrition. The inclusion of rye and RSM instead of wheat and SBM may increase dietary fibre content in the feed, which may affect digestive physiology and intestinal function. However, research on the combined feeding of rye and RSM in piglets is still scarce. The a...
Strategies to combat microbiota-associated health problems are of high interest in pig production. Successful intervention strategies with beneficial long-term effects are still missing. Most studies on pig microbiota have been conducted under standardized experimental conditions, but the situation in commercial farms differs dramatically. This stu...
Background
Microbial colonization and immune cell maturation coincide at mucosal sites and are decisive for postnatal lung development. How external factors influence neonatal pulmonary immune development is poorly understood.
Objective
To elucidate the impact of key determinants in early life, nutrition, and maternal bonding, on postnatal lung ma...
The use of food residues for animal nutrition might imply ecological and economic advantages; however, their effects as a potential ingredient have not yet been evaluated in dogs. In the present study, four diets with 0, 5, 10 and 15% dried food residues (DFR), derived from hotel catering, were fed to 10 healthy adult dogs. At the end of each three...
Purpose:
Ellagitannins are high molecular weight polyphenols present in high quantities in various food products. They are metabolized by human and animal gut microbiota to postbiotic metabolites-urolithins, bioavailable molecules of a low molecular weight. Following absorption in the gut, urolithins rapidly undergo phase II metabolism. Thus, to f...
Ethnopharmacological relevance
Solidago virgaurea L. (also known as European goldenrod) is a pharmacopoeial plant material popularly used by patients in the form of an infusion. It was traditionally used in Europe and North America for the treatment of urinary tract conditions. It is also reported as a topical agent for skin disorders.
Aim of the...
In order to evaluate the potential prebiotic effects of cellobiose, 10 healthy adult research beagle dogs received a complete diet containing 0, 0.5 and 1 g cellobiose/kg bodyweight (BW)/day. At the end of each feeding period, faeces, urine and blood of the dogs were collected. The results demonstrated a significant increase of faecal lactate conce...
Lythrum salicaria herb (LSH) was applied in diarrhea therapy since ancient times. Despite empirically referenced therapeutic effects, the bioactivity mechanisms and chemical constituents responsible for pharmacological activity remain not fully resolved. Taking into consideration the historical use of LSH in treatment of diarrhea in humans and farm...
Insects have experienced an increasing interest as a protein source in recent years. However, their suitability as a protein source for dogs was not yet widely investigated. Therefore, the aim of the study was to compare two extruded diets for adult dogs containing either larvae meal from black soldier fly (Hermetia illucens; HI) or lamb meal as th...