Judita Kinkorova

Teaching Hospital and Medical faculty Charles University in Pilsen

The incidence of cancer is expected to rise globally, with low-and middle-income countries affected disproportionally. One of those countries, Armenia, also faces the challenge of exhibiting one of the lowest research and scientific publication rates within Europe on cancer research. This report presents the experiences of the Twinning for the Arme...

The COVID-19 pandemic has dramatically affected spa and balneology not only in the Czech Republic. Generally, almost two years without spa patients and clients led to a dramatic outflow of labor. The article main purpose is to analyze pandemic impact on the structure of spa patients and clients, to identify main current spa problems to be overcome,...

Horizon Europe is the 9th framework programme of European Union (EU) funding research and innovation with the biggest budget ever of €95.5 billion. The main aims of the programme are to boost competitiveness and growth of European Union, to achieve EU sustainable development and to tackle climate change. The programme facilitates collaboration betw...

Biobanking as a quickly growing branch of personalised medicine has undergone enormous progress during last two decades. Nowadays it is a well developed and structured multidisciplinary field that reflects developments and advances of biomedical research based on principles of predictive, preventive and personalised medicine (PPPM/3PM). All these t...

Biobanking is entering the new era—era of big data. New technologies, techniques, and knowledge opened the potential of the whole domain of biobanking. Biobanks collect, analyse, store, and share the samples and associated data. Both samples and especially associated data are growing enormously, and new innovative approaches are required to handle...

Informed consent is an important document for every existing biobank or repository to obtain, store and use human biospecimens and associated data and information for current and future research. Biobanks have undergone great progress worldwide during the last three decades and have become an integral part of personalized medicine and health care s...

The 39th annual conference: Immunoanalytical Days took place between 11th and 13th of March 2018 in Pilsen, Czech Republic. The title was: Personalised medicine, biobanks and biomarkers for the optimal approach to the patient. The conference was co-organized by the Czech Society of Nuclear Medicine, the Czech Society of Clinical Biochemistry, the U...

this conference has a long history and covers current scientific and research problems. the title was: personalised medicine, biobanks and biomarkers for optimal approach to the patient. conference attended 150 participants form Europe and all over the world, and contributed to the exchange of knowledge and experience in the wide field of personali...

Biobanks have during last two decades gained an important role in the whole process of biomedical research and health care not only in Europe but also worldwide. Biobanks are one of the pillars in personalised medicine tackling all its aspects such as prevention, diagnosis, treatment and monitoring closely the specific characteristics of an individ...

Introduction: PSA is a serine protease composed of 240 amino acids in a single polypeptide chain and is a routine parameter in prostate cancer diagnostics. The aim of our study was to test the long-term stability of tPSA and fPSA after 10 years' storage at -80°C. Materials and methods: We analyzed two aliquots from 55 serum samples. The first wa...

The 44th Congress of the International Society of Oncology and Biomarkers: Rio de Janeiro, Brazil, 7–10 September 2017 The 44th congress followed the previous one of International Society of Oncology and Biomarkers (ISOBM) that took place in Chicago (USA) in 2016. The title of the 44th Annual congress was: ‘Biomarkers in oncology: new horizons and...

Biobanks are an important pillar of personalised medicine, and strongly support the scientific progress in stratification of population, biomarkers discovery and validation, and due to progress in personalised medicine. Biobanks are significant tool for new drug discoveries and drug development. Biobanks play an important role in the whole process...

Biobanks are structured repositories of human tissue samples connected with specific information. They became an integral part of personalized medicine In the new millennium. At the European research area biobanks are Isolated not well coordinated and connected to the network. European commission supports European Infrastructure BBMRI-ERIC (Biobank...

Plurality and individuality of hepatocellular carcinoma: PPPM perspectives Krishna Chander Sridhar, Olga Golubnitschaja Department of Radiology, Univeristy of Bonn, Bonn, Germany Correspondence: Olga Golubnitschaja (olga.golubnitschaja@ukb.uni-bonn.de) – Department of Radiology, Univeristy of Bonn, Bonn, Germany The EPMA Journal 2016, 7(Suppl 1)...

Aim: The aim of the study was to assess the degree to which TPS and TPA can assist in the detection of distant metastases. Patients and Methods: We assessed 157 patients divided into two groups. The first was a group of colorectal and breast cancer patients at stages 1, 2 and 3. The second was a group of colorectal and breast cancer patients at sta...

Signaling pathway of IGF1 belongs to the most important growth pathways in the body. This pathway has been studied for many years in connection with the growth and survival of cells. Our publication is based on the latest knowledge and our own experience and actually maps the system of growth managing of the organism - from the hypothalamus to the...

Chronic diseases are the leading causes of morbidity and mortality in Europe, accounting for more than 2/3 of all death causes and 75 % of the healthcare costs. Heart failure is one of the most prominent, prevalent and complex chronic conditions and is accompanied with multiple other chronic diseases. The current approach to care has important shor...

Biobanks are an important compound of personalized medicine and strongly support the scientific progress in stratification of population and biomarker discovery and validation due to progress in personalized medicine. Biobanks are an essential tool for new drug discoveries and drug development. Biobanks play an important role in the whole process o...

Objective: Monitoring and evaluation of benefit of the soluble cytokeratin fragments determination for the liver metastases diagnostics. Design: Combinated retrospective and prospective study Settings: Faculty Hospital Pilsen, Charles University in Prague, Faculty of Medicine in Pilsen, Czech Republic Material and Methods: In the period from Janua...

The aim of the present study was to evaluate the usefulness of four interleukins (IL-2, IL-6, IL-8 and IL-10) for melanoma detection and correlate these interleukins with sentinel node metastasis positivity. A group of 236 persons was assessed: 175 patients with melanomas and 61 healthy persons. Melanoma patients were divided to four groups accordi...

IGF1 is responsible for regulation of growth, metabolism, and differentiation of human cells. IGFBP3 is the most abundant of the carrier proteins for IGF1 in the blood. IGF1/IGFBP3 molar ratio is an indicator of IGF1 bioavailability. We decided to create a file of reference ranges of IGF1, IGFBP3 and IGF1/IGFBPP3 ratio for the adult Czech populatio...

Objective: Monitoring and evaluation of benefit of the soluble cytokeratin fragments determination for the liver metastases diagnostics. Design: Combined retrospective and prospective study. Material and Methods: In the period from January 2010 to December 2014 was in the Laboratory of immunoanalysis examined 1616 serum samples of patients from lun...

Horizon 2020 is a financial instrument implementing the Innovation Union, a Europe 2020 flagship initiative aimed at securing Europes global competitiveness. Running from 2014 to 2020 with a budget of just over € 80 billion, the EUs new programme for research and innovation is part of the drive to create new growth and jobs in Europe. Societal chal...

The European Association for Predictive, Preventive and Personalised Medicine (EPMA) considers acute problems in medical sciences as well as the quality and management of medical services challenging health care systems in Europe and worldwide. This actuality has motivated the representatives of EPMA to comment on the efforts in promoting an integr...

European Commission has announced the first preliminary results of participation in the 7th Framework Programme (FP7), priority Health. The overview presents the basic statistics regarding the participation of the Czech teams, universities, institutions, and small and medium size enterprises (SMEs) in FP7 projects. The aim of the article is to pres...

The aim of the Joint Program-ming process is to pool national research efforts in order to make better use of European precious public research and development resources and to tackle common European challenges more effectively in a few key areas. Joint programming is a structured and strategic process whereby Member States agree, on a voluntary ba...

Portal vein embolization (PVE) may increase the resectability of liver metastases. However, the problem of PVE is insufficient growth of the liver or tumor progression in some patients. The aim of this study was to evaluate the significance of commonly available clinical factors for the result of PVE. Portal vein embolization was performed in 38 pa...

The healthcare system in the Czech Republic underwent and still is undergoing dramatic changes since the Velvet revolution in 1989. History of the Czech healthcare system, main healthcare laws, and the current status of healthcare documented in the main healthcare indicators is described based on the several main sources as well as delivery of heal...

This report is the collective product of word-leading experts working in the branches of integrative medicine by predictive, preventive and personalised medicine (PPPM) under the coordination of the European Association for Predictive, Preventive and Personalised Medicine. The general report has been prepared as the consortium document proposed at...

The healthcare system in the Czech Republic has undergone and still is undergoing dramatical changes since the Velvet revolution in 1989. A brief history of a Czech healthcare system from the beginning in 1883, through the World Wars I. and II., and later during a period of being a part Soviet sphere countries is given. Main healthcare laws and the...

International cooperation, in EU -funded health research with research partners on five continents, with project opportunities is open to applicants from every country on the map, with generous funding for international teams exploring issues of relevance to the global community, the EU is fostering ambitious undertakings involving scientists and o...

The work describes the emergence and development of personalized medicine in biomedical research. We discuss the current status of personalized medicine in Europe, in the world, and in the Czech Republic, and its prospects and perspectives.

Eighth framework programme (FP8) of the European Union for years 2014-2020 undergoes the preparatory process. The overview presents current status of the programme preparation. European Commission organized three workshops (-omics in personalised medicine, 4D biology for health and disease, and Stratification biomarkers in personalised medicine) wi...

Chaetostomella cylindrica (Robineau-Desvoidy) is a polyphagous fly widely distributed in most of Europe. Its life history, with emphasis oil the previously unknown developmental stages, and reproductive behavior, is described. The development of C. cylindrica was followed oil the knapweed Centaurea pseudophrygia C.A.Meyer (Asteraceae) that has been...

The tephritid fauna in California was studied in May and June 2002 on a two-week field trip and in September 2003 during a 16-day round trip through most of California. Records are given for 22 species of Tephritidae from 26 collection sites. Establishment of three introduced species, Urophora jaculata Rondani, Terellia fuscicornis (Loew), and Chae...

The community structure and population dynamics of Heteroptera was studied in an apple orchard in the Czech Republic, between 1992 and 1995. The study investigated the changes which occurred after introduction of integrated pest management (IPM) practices into an intensive apple orchard. The IPM consisted of establishing grass ground cover or plant...

Cirsium vulgare is a widespread weed in Czechoslovakia. U. stylata produces galls in the flower heads of this weed causing a reduction in the number of achenes. T. serratulae does not produce galls, but larve feeding on achenes decrease the seed production of the host plant. Larvae of both specis can develop in the same flower head and thus it is r...