Juan Camilo Jaramillo-Bustamante

University CES | CES · Facultad de Medicina

Background Strong social distancing measures were quickly implemented in Chile during the SARS-CoV-2 outbreak. One of the aims of non-pharmaceutical interventions (NPI) mandates was to decrease overcrowding, thus is usually measured as mobility changes. Methods we gather data from national health statistics for pediatric emergency (PED) visits for...

Versión en Español del 1er Consenso Latinoamericano de Sepsis con link de acceso directo al artículo completo con soporte de evidencia de cada recomendación.

Objective To compare the safety and effectiveness of Continuous Positive Airway Pressure (CPAP) vs. High Flow Nasal Cannula (HFNC) to prevent therapeutic failure and the need of invasive ventilation in children with acute moderate-severe bronchiolitis. Design A systematic review and meta-analysis. Setting Medline, Embase, Lilacs, Cochrane and gra...

Sepsis is a worldwide public health problem due to its high incidence and accompanying mortality, morbidity, and financial burden. It is a major cause of admission to paediatric intensive care units; despite advances in the diagnosis and treatment, both incidence and mortality are high in low-income and middle-income countries. There are several ba...

These guidelines seek to generate recommendations based on the best available evidence, including local and regional studies in countries with limited resources, which do not replace individual clinical judgement in the care of children with sepsis. The intention is not to replace the SSC or other existing guidelines; on the contrary, the purpose i...

Abstract Objective: to develop evidence-based recommendations for the diagnosis and treatment of sepsis in children in low- and middle-income countries (LMICs), more specifically, in Latin America. Design: a panel was formed consisting of 27 experts with experience in the treatment of pediatric sepsis, and two methodologists working in Latin Americ...

Objective The aim of this study was to develop evidence-based recommendations for the diagnosis and treatment of sepsis in children in low- and middle-income countries (LMICs), more specifically in Latin America. Design: A panel was formed consisting of 27 experts with experience in the treatment of pediatric sepsis and two methodologists working i...

Background The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 (MIS-C) is widespread and presents a very low mortality rate in high-income countries. This research describes the clinical characteristics of MIS-C in critically ill children in middle-income countries and the factors associa...

The Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children was released in 2020 and is intended for use in all global settings that care for children with sepsis. However, practitioners managing children with sepsis in resource-limited settings (RLS) face several cha...

Importance: Multisystem Inflammatory Syndrome in Children (MIS-C) associated with SARS-CoV-2 infection is thought to be driven by a post-viral dysregulated immune response, where interleukin 6 (IL-6) might have a central role. In this setting, IL-6 inhibitors are prescribed as immunomodulation in cases refractory to standard therapy. Objective: To...

Several challenges exist for referral and transport of critically ill children in resource-limited regions such as Latin America; however, little is known about factors associated with clinical outcomes. Thus, we aimed to describe the characteristics of critically ill children in Latin America transferred to pediatric intensive care units for acute...

SECCION VI. Población pediátrica

Background The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 is widespread and presents a very low mortality rate in highincome countries. This research describes the clinical characteristics of MIS-C in critically ill children in middle-income countries compared to described series in...

Aims & Objectives: To describe the epidemiology, therapeutic management and outcomes of children admitted to pediatric ICU (PICU) for acute respiratory failure (ARF) in a contemporary multinational PICU cohort. Methods: Retrospective analysis using prospectively collected clinical data within the LARed Network ARF clinical registry (35 hospitals,...

Aims & Objectives: to describe contemporary invasive mechanical ventilation (IMV) practices in children admitted to Latin American PICUs with acute respiratory failure (ARF). Methods: Retrospective analysis within LARed Network ARF Registry. We analyzed all children who were prescribed IMV between May 2017 and October 2019. Data described as median...

Aims & Objectives: To determine risk factors of non-invasive ventilation techniques (NIV) failure in children admitted with acute respiratory failure (ARF) and to compare their outcomes with children treated successfully or with invasive ventilation alone (IMV). Methods: Retrospective analysis within LARed Network ARF multicenter registry. We inclu...

Aims & Objectives: To compare Bedside Physician Diagnosis (BPD) for pediatric sepsis with the new infection associated organ failure Consensus Criteria (CC) on a large Latin American registry To describe the clinical outcomes of ventilated patients with a respiratory infection. Methods:Design: Retrospective analysis within LARed Network’s Pediatric...

Aims & Objectives: To develop a comprehensive description of multisystem inflammatory syndrome temporally associated with SARS -Cov-2 (PIMS-TS) by conducting a case series quantitative systematic review. Methods: PIMS-TS studies were identified by searching Pub Med and Embase from May 1st to July 1st 2020.We extracted data on demographics, clinica...

Pediatric inflammatory multisystem syndrome associated with SARS-CoV-2 (PIMS-TS) is infrequent, but children might present as a life-threatening disease. In a systematic quantitative review, we analyzed 11 studies PIMS-TS, including 468 children reported before Jul 1st. We found a myriad of clinical features, but we were able to describe common cha...

Una nueva pandemia fue declarada por la Organización Mundial de la Salud por elvirus SARS-CoV-2 recientemente. Este virus se caracteriza por ser altamente transmisible, letaly afectar a todos los grupos etarios. Esta declaración permitió la activación en todos los paí-ses de mecanismos de urgencia para atender esta crisis de salud pública que ha ex...

Objective To compare the safety and effectiveness of Continuous Positive Airway Pressure (CPAP) vs. High Flow Nasal Cannula (HFNC) to prevent therapeutic failure and the need of invasive ventilation in children with acute moderate-severe bronchiolitis. Design A systematic review and meta-analysis. Setting Medline, Embase, Lilacs, Cochrane and gra...

Multisystem inflammatory syndrome temporally related to COVID-19 in children and adolescents is a clinical presentation of SARS-CoV-2 infection. It shares some features with Kawasaki disease, toxic shock, sepsis, macrophage activation syndrome, and myocarditis. Few publications have addressed its initial management, which is similar to that propose...

Background: The COVID-19 pandemic reached the Southern Hemisphere in the autumn of 2020, thus coinciding with its expected annual viral respiratory season. The potential impact of national strategies aimed at mitigating COVID-19 during the pandemic on the incidence of other critical viral lower respiratory tract infections (LRTIs) in children is un...

ARTÍCULO DE REVISIÓN Resumen El enfoque moderno de la sepsis se ha centrado en la creación de consensos globales que utilizan distintos criterios para pesquisarla en forma precoz, con el fin de disminuir la morbimortalidad asociada a ella. Hasta la aparición del tercer y últi-mo consenso de adultos (Sepsis-3), el síndrome de respuesta inflamatoria...

A pesar de que la infección es más prevalente en los adultos; el número de casos en la población pediátrica ha ido en aumento. La presentación clínica es variable y puede ir desde una infección asintomática hasta presentarse como insuficiencia respiratoria aguda, requiriendo manejo en la unidad de cuidados intensivos. En la población pediátrica, so...

INTRODUCCIÓN. La Bronquiolitis grave (BG) es causa principal mundial de ingreso a unidades de cuidado intensivo pediátrico (UCIP). La variabilidad de prácticas en su manejo es extendida y en Colombia aún no ha sido descrita. OBJETIVO. Caracterización epidemiológica de niños admitidos por BG en 3 UCIP adscritas a una red colaborativa (LARed Network...

Objetivo: Describir terapias utilizadas lactantes con bronquiolitis aguda admitidos en 20 Unidades de Cuidados Intensivos (UCI) pediátricos miembros de LARed en 5 países latinoamericanos. Pacientes y métodos: Estudio observacional retrospectivo, multicéntrico, de datos recabados en forma prospectiva en Registro Latinoamericano de Falla Respiratori...

INTRODUCCION. La Bronquiolitis grave (BG) es causa principal mundial de ingreso a unidades de cuidado intensivo pediátrico (UCIP). La variabilidad de prácticas en su manejo es extendida y en Colombia aún no ha sido descrita. OBJETIVO. Caracterización epidemiológica de niños admitidos por BG en 3 UCIP adscritas a una red colaborativa (LARed Network...

The goal was to reach consensus with all the participating experts for every recommendation. An agreement of at least 80% of the participating experts had to exist in order to deliver a recommendation. Two Delphi voting rounds were sent out electronically. The experts were asked to score between 1 and 9 their level of agreement for each recommendat...

Design: Expert consensus recommendations with Delphi methodology. Setting: Latin American countries. Subjects: Experts in pediatric cardiopulmonary resuscitation from Interventions: Delphi methodology for expert consensus. Measurements and Main Results: The goal was to reach consensus with all the participating experts for every recommendation. An...

Resumen Las unidades de cuidados intensivos están concebidas para atender niños críticamente enfermos; en ellas se reúne personal médico y paramédico altamente capacitado y tecnología de punta buscando la mejor atención de estos pacientes, con el fin de lograr su estabilización y mejoría, con las mínimas secuelas posibles. Debido a que se trata de...

Vasconcellea spp., is a species of Andean papaya commonly cultivated in rural communities close to Medellin, Colombia. Due to the pleasant and sweet flavor of its fruits, children frequently ingest its seeds accidentally. After ingestion, the seeds are engaged in the colonic lumen and block the exit of stools, causing pain and bloating, and promoti...

Rationale: Limited data exist about the international burden of severe sepsis in critically ill children. Objectives: To characterize the global prevalence, therapies, and outcomes of severe sepsis in pediatric intensive care units to better inform interventional trials. Methods: A point prevalence study was conducted on 5 days throughout 2013...

: In 2002, the Surviving Sepsis Campaign pointed out the need to recognize sepsis as an important cause of death and high economic and social costs. There are few epidemiologic studies of this disease in pediatrics and none in Colombia. The objective of this study was to describe the sociodemographic and clinical characteristics of patients with se...

In 2002, the Surviving sepsis campaign defined a strategy that aimed to reduce the high mortality due to sepsis. One point of this strategy was a recommendation to recognize that the sepsis is an important cause of deaths and high economic costs in the pediatric intensive care units. Knowledge of the disease is the first step to impact it. There ar...

BACKGROUND: Even though the implementation of the Law 100 of 1993 has given rise to profound changes in the medical attention services and working conditions of health service personnel, there are few studies that explore the impact on the latter. The purpose of the present study was to describe the current situation of pediatricians and pediatric...

The Kawasaki disease is a systemic vasculitis that mainly affects children under five years. It has become the first cause of acquired cardiac illnesses in industrialized countries. Although it can be a self-limited disease, it usually damages medium caliber arteries, especially the coronaries, causing serious sequels and even death. Aside from car...