Juan C Ramirez-Sandoval

Juan C Ramirez-Sandoval
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán | INNSZ · Department of Nephrology and Mineral Metabolism

MD and MSc

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49
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191
Citations

Publications

Publications (49)
Article
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein expressed by kidney tubular cells in response to ischemia, but may also be an early indicator of immunological rejection, calcineurin inhibitor toxicity, obstructive nephropathy, subclinical tubulitis or infection. Although there is currently no evidence to support the routine serial me...
Article
Full-text available
Unlabelled: ♦ Background: Vascular calcification is strongly associated with cardiovascular disease and mortality. However, some factors related to vascular calcification in patients with end-stage renal disease receiving peritoneal dialysis (PD) remain unknown. This study aimed to evaluate the associations of osteoprotegerin (OPG), osteopontin...
Article
Full-text available
Ramirez-Sandoval, Juan C., Maria F. Castilla-Peón, José Gotés-Palazuelos, Juan C. Vázquez-García, Michael P. Wagner, Carlos A. Merelo-Arias, Olynka Vega-Vega, Rodolfo Rincón-Pedrero, and Ricardo Correa-Rotter. Bicarbonate values for healthy residents living in cities above 1500 m of altitude: a theoretical model and systematic review. High Alt Med...
Article
Full-text available
Background Vitamin D deficiency is common in peritoneal dialysis (PD) patients, so its supplementation has been advocated as potentially beneficial. Methods Double-blind, placebo-controlled, randomized clinical trial. Subjects on PD treated with high calcium peritoneal dialysate (Ca 3.5 mEq/l) and serum levels of 25-hydroxi vitamin D (25D) < 20 ng...
Article
Introduction: The protein-energy wasting (PEW) syndrome is a common complication in hemodialysis (HD) patients associated to morbidity and mortality. Our objective was to assess the prevalence of PEW and its association with erythropoietin resistance index (ERI) score, body composition by impedance, health-related quality of life, and muscle stren...
Article
Full-text available
Background: Acute kidney injury (AKI) is a common complication of COVID-19. Several etiologies have been identified, including pigment deposition likely associated with myopathic damage. Nevertheless, the relationship between longitudinal creatine-kinase trends and renal outcomes is uncertain. Aim: To correlate longitudinal changes in serum crea...
Article
Full-text available
Purpose Free calcium is the gold standard for diagnosis of calcium disorders, although calcium assessment is routinely performed by albumin-adjusted calcium. Our objective was to develop a novel-specific correction equation for free calcium employing serum total calcium and other analytes. Methods Retrospective single-center cohort study. A new eq...
Book
Nefrología de bolsillo es una referenciaconcisa y práctica que brinda conocimiento y recomendaciones actualizadas y basadas en evidencia creadas por expertos del reconocido Columbia University Medical Center. En un formato conciso y de búsqueda rápida, Nefología de bolsillo puede ser utilizado como una referencia portable con el diagnóstico y opcio...
Article
Full-text available
Background . There is controversy regarding the association between hypovitaminosis D and COVID-19 outcomes. Aim of the study . We assessed the association between 25-hydroxyvitamin D levels and COVID-19 outcomes in hospitalized subjects with severe SARS-CoV-2 infection. Methods . Retrospective cohort study. Serum 25-hydroxyvitamin D levels of su...
Article
Full-text available
El hiperparatiroidismo secundario grave relacionado con la enfermedad renal crónica avanzada es una complicación acompañada de morbimortalidad cuyo diagnóstico y tratamiento son complejos. La interpretación de las mediciones de la hormona paratiroidea molécula intacta y las opciones terapéuticas con calcimiméticos, vitamina D, paratiroidectomía o m...
Article
Introduction: Acute kidney injury (AKI) is common in coronavirus disease 2019 (COVID-19). It is unknown if hospital-acquired AKI (HA-AKI) and community-acquired AKI (CA-AKI) convey a distinct prognosis. Methods: The study aim was to evaluate the incidence and risk factors associated with both CA-AKI and HA-AKI. Consecutive patients hospitalized...
Article
Aim Severe hypocalcemia following parathyroidectomy for secondary or tertiary hyperparathyroidism (SHPT/THPT) is scarcely studied. We aimed to describe and identify risk factors for early and persistent hypocalcemia after parathyroidectomy. Methods Retrospective pair‐matched cohort study. We assessed 87 dialysis patients with SHPT (n=73) or THPT (...
Article
Full-text available
Background Sequential inhibition of the vascular endothelial growth factor (VEGF) pathway with sorafenib could be useful for patients with metastatic renal cell carcinoma (RCC). Our aim was to determine the activity and tolerability of sorafenib as a second-line therapy in advanced RCC initially treated with a different VEGF-tyrosine kinase inhibit...
Chapter
Ethnicity is a powerful element that affects the incidence, prevalence, and course of chronic kidney disease (CKD) worldwide. Complex interactions of genetic, biologic, cultural, environmental, and socioeconomic factors are associated with CKD differences among countries, including several disadvantaged communities and ethnic minorities in develope...
Article
Introduction: Patients with acute respiratory distress syndrome (ARDS) secondary to COVID-19 frequently develop severe acute kidney injury (AKI). Although continuous renal replacement therapy is the standard of care for critically ill patients, prolonged intermittent renal replacement therapy (PIRRT) may be a feasible option. We aimed to describe t...
Preprint
Full-text available
Background: Sequential inhibition of the vascular endothelial growth factor (VEGF) pathway with sorafenib could be useful for patients with metastatic renal cell carcinoma (RCC). Our aim was to determine the activity and tolerability of sorafenib as a second-line therapy in advanced RCC initially treated with a different VEGF-tyrosine kinase inhibi...
Preprint
Full-text available
Background: Sequential inhibition of the vascular endothelial growth factor (VEGF) pathway with sorafenib could be useful for patients with metastatic renal cell carcinoma (RCC). Our aim was to determine the activity and tolerability of sorafenib as a second-line therapy in advanced RCC initially treated with a different VEGF-tyrosine kinase inhibi...
Preprint
Full-text available
Background: Sequential inhibition of the vascular endothelial growth factor (VEGF) pathway with sorafenib could be useful for patients with metastatic renal cell carcinoma (RCC). Our aim was to determine the activity and tolerability of sorafenib as a second-line therapy in advanced RCC initially treated with a different VEGF-tyrosine kinase inhibi...
Article
Full-text available
Background and Aims The FGF23-lowering effect of different phosphate-sources (vegetable versus animal) in low-phosphorus diets are scarcely known. In this trial, we assess the effect on intact FGF23 (iFGF23) of two low-phosphorus diets, animal versus mixed (vegetable + animal), in dialysis patients. Method A randomized, two-center, open-label, cli...
Article
e17077 Background: Sequential inhibition of the vascular endothelial growth factor (VEGF) pathway with sorafenib could be useful for patients with advanced or metastatic renal cell carcinoma (RCC). Our aim was to determine the activity and tolerability of sorafenib as a 2nd-line therapy in advanced RCC initially treated with a different VEGF-tyrosi...
Article
Full-text available
Clinical Presentation A 27-year-old woman was hospitalized for the treatment of new-onset seizures, fever, tachycardia, hyper-tensive crisis, and anasarca. Two weeks prior, severe hyperthyroidism with thyroid storm was diagnosed (Burch-Wartofsky score, 60 points) and she was treated with potassium iodide-iodine (Lugol solution), hy-drocortisone, me...
Data
Sorafenib as a Second-Line Treatment in Metastatic Renal Cell Carcinoma: A Prospective Cohort Study
Data
A new formula to predict Free Calcium. Download app for IOS (it´s free!!!) https://apps.apple.com/mx/app/true-calcium/id1479639808?l=en https://www.asn-online.org/education/kidneyweek/2019/program-abstract.aspx?controlId=3233853 Authors Ramirez-Sandoval, Juan Carlos, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, México cit...
Poster
Authors Ramirez-Sandoval, Juan Carlos, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico Paz-Cortes, Jose A., Universidad Nacional Autónoma de México, Mexico City, Mexico García-Sánchez, Lourdes G., Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico Vergara-Juarez, Josue J...
Article
Full-text available
Kidney transplant (KT) is the best treatment for patients who progress to end-stage renal disease. Short-term outcomes in patients with systemic lupus erythematosus (SLE) following KT are not well known. To describe the postoperative outcomes and complications in SLE patients undergoing KT, we conducted a case–control study from 2010 to 2015 includ...
Presentation
Full-text available
Presentación en el marco del curso anual del IMIN, celebrado el 26 de junio de 2019 en el auditorio del Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Article
Kidney transplant for patients with lupus nephritis (LN) has satisfactory outcomes in studies with short-term or mid-term follow up. Nevertheless, information about long-term outcomes is scarce. We performed a retrospective matched-pair cohort study in 74 LN recipients compared with 148 non-LN controls matched by age, sex, immunosuppressive treatme...
Article
Hyperuricemia may be a major contributor to the development or progression of chronic kidney disease (CKD). Although there is no clear cutoff uric acid (UA) value associated to the risk for kidney damage, it appears to be an increased risk as UA rises. Lifestyle interventions such as exercise, weight reduction, low consumption of purine-rich meat,...
Article
Full-text available
We report a case of capillary leak that developed during treatment of antibody-mediated rejection in a kidney transplant recipient. A 53-year-old female transplant recipient experienced an increase in serum creatinine from 1.1 to 1.8 mg/dL. Antibody-mediated rejection was diagnosed by graft biopsy. She was treated with five plasmapheresis sessions...
Article
Full-text available
Individuals with chronic kidney disease (CKD), especially older adults, are at increased risk of developing cognitive impairment associated with renal disease, may present as minor neurocognitive disorder (NMS) or as a major neurocognitive disorder (dementia). Studies have shown that up to 87% of patients in the final stage of CKD have some degree...
Chapter
Hyperuricemia may be a major contributor to the development or progression of chronic kidney disease (CKD). Although there is no clear cutoff uric acid (UA) value associated to the risk for kidney damage, it appears to be an increased risk as UA rises. Lifestyle interventions such as exercise, weight reduction, low consumption of purine-rich meat,...
Poster
Full-text available
HBS was a common complication after PTx and closely related to severity of HPT. At one year of follow up it was associated with continued prescription of higher doses of calcium and calcitriol. Consequences of this prolonged exposure to calcium and calcitriol could have deleterious systemic/vascular complications. Preoperative prophylactic calcitri...
Article
Purpose: The use of colistin for multi-drug resistant (MDR) infections has led to an increase of colistin-associated acute kidney injury (AKI). Nevertheless, information on long-term renal prognosis is scarce. We aimed to determine the predictors of chronic kidney disease (CKD) in survivors of MDR-infections with colistin-associated AKI. Methods:...
Article
Controversy exists with regard to the causal role of hyperuricemia in chronic kidney disease. Vascular stiffness may be the link that explains the relation between hyperuricemia and kidney disease. Hyperuricemia is associated with a number of effects on the vascular endothelium and vascular smooth muscle cells, including an increase in oxidative st...
Chapter
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein expressed by kidney tubular cells in response to ischemia but may also be an early indicator of immunological rejection, calcineurin inhibitor toxicity, obstructive nephropathy, subclinical tubulitis, or infection. Although there is currently no evidence to support the routine serial me...
Chapter
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein expressed by kidney tubular cells in response to ischemia but may also be an early indicator of immunological rejection, calcineurin inhibitor toxicity, obstructive nephropathy, subclinical tubulitis, or infection. Although there is currently no evidence to support the routine serial me...
Article
Full-text available
Los diseños de investigación clínica, cuyo propósito es responder preguntas sobre causalidad, se pueden clasificar en relación con cuatro ejes: el número de grupos de estudio, la aplicación de una maniobra experimental, la direccionalidad causa-efecto y la fuente de la que se recaban los datos. Los diseños básicos más utilizados en epidemiología so...
Book
A change in the epidemiology of disease has occurred across the world. There has been a marked increase in the incidence and prevalence of chronic non-communicable disease including CKD in most countries. Rates of CKD in parts of the world outside the United States may be affected by factors related to lower socioeconomic status, racial heritage, a...
Chapter
A change in the epidemiology of disease has occurred across the world. There has been a marked increase in the incidence and prevalence of chronic non-communicable disease including CKD in most countries. Rates of CKD in parts of the world outside the United States may be affected by factors related to lower socioeconomic status, racial heritage, a...
Book
Inadequate predialysis nephrological care may be strongly associated with morbidity and mortality during the first months of dialysis. Careful planning before dialysis initiation should prevent hospitalizations for the management of untreated acute or chronic complications of advanced uremia and should allow the use of a functioning permanent acces...
Article
To evaluate the performance of urinary neutrophil gelatinase-associated lipocalin (uNGAL), kidney injury molecule, interleukin-18, and heat shock protein 72 for differential diagnosis between causes of acute kidney injury in kidney transplant recipients, especially immunological rejection. We measured these biomarkers in 67 kidney transplant recipi...
Article
Objective: Establish the prognostic value for graft loss of urinary neutrophil gelatinase-associated lipocalin (uNGAL), kidney injury molecule-1 (uKIM-1), interleukin-18 (uIL-18), and heat shock protein 72 (uHsp72) in kidney transplant recipients (KTR) with acute kidney injury (AKI). Methods: Biomarkers were measured in 67 KTR with AKI caused by...
Article
Full-text available
La prevalencia de la enfermedad renal crónica(ERC) ha aumentado progresivamente en las últimas décadas, convirtiéndose en una necesidad prioritaria de salud pública su detección y tratamiento tempranos. Desafortunadamente, la referencia al nefrólogo frecuentemente ocurre en estadios avanzados de la ERC. El presente artículo plantea la necesidad de...

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