Joy Perrier

Joy Perrier
Unité Inserm U1077

PhD

About

36
Publications
19,064
Reads
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270
Citations
Introduction
I am currently working at Unité Inserm/EPHE/PSL/Unicaen U1077 (Caen) as a postdoctorate (Chaire d'Excellence, Normandy Region) directed by Prof. Hervé Platel. My research focus on the sleep modifications associated with (breast) cancer and the impacts on cognition.
Additional affiliations
January 2017 - present
Unité Inserm U1077
Position
  • Fellow
January 2015 - May 2016
Netherlands Institute for Neuroscience
Position
  • Project Manager
Description
  • Our project aims to investigate the neural basis of the daytime deficits of primary insomnia patients.
September 2012 - September 2013
Maastricht University
Position
  • PhD Student

Publications

Publications (36)
Article
Full-text available
Complaints of sleep disturbance are prevalent among breast cancer (BC) patients and are predictors of quality of life. Still, electrophysiological measures of sleep are missing in patients, which prevents from understanding the pathophysiological consequences of cancer and its past treatments. Using polysomnography, sleep can be investigated in ter...
Article
Rest-activity rhythm (RAR) disruptions are frequently associated with chemotherapy in breast cancer (BC), but they are less known in BC with endocrine therapy. The aim of this ancillary study was to characterize the RAR and estimated sleep characteristics from actigraphy in BC patients either treated (ET+) or untreated with endocrine therapy (ET-),...
Article
Full-text available
Patients with non-central nervous system (CNS) cancer frequently report cognitive complaints, that are recurrent and affect their quality of life. In order to improve supportive care of these cognitive difficulties, it is important to identify associated factors. Sleep disturbance is a good candidate to study, as patients with non-CNS cancer freque...
Article
Résumé Les patientes atteintes d’un cancer du sein se plaignent fréquemment d’une altération de leur sommeil. Ce dernier joue un rôle crucial dans le fonctionnement cognitif, notamment dans les fonctions exécutives telles que la planification ou la flexibilité, ou encore dans la consolidation des souvenirs en mémoire à long terme. Ces fonctions cog...
Poster
Full-text available
Objectif L’objectif de cette étude était d’analyser les spindles, acteurs fondamentaux de la consolidation mnésique au cours du sommeil, et leurs liens avec la consolidation d’intentions en mémoire prospective (mémoire des actions à réaliser dans le futur, MP) chez des patientes traitées pour un cancer du sein. Méthodes Nous avons enregistré le so...
Article
Full-text available
Objectif L’objectif de cette étude était de décrire les corrélats neuronaux de la performance de conduite chez des patients atteints d’insomnie. Méthodes Les données issues d’une tâche en conduite automobile monotone ont été acquises pendant l’enregistrement de l’activité cérébrale en imagerie par resonance magnetique fonctionnelle (IRMf). Au tota...
Poster
Full-text available
Objectif Évaluer la macrostructure du sommeil de patientes traitées pour un cancer du sein et son influence sur la consolidation en mémoire prospective (MP). Méthodes Dix-huit patientes traitées par hormonothérapie pour un cancer du sein et 21 volontaires sains de même âge et niveau d’études ont réalisé le protocole. Le sommeil était évalué à l’ai...
Article
Full-text available
Cognitive deficits are a major complaint in breast cancer patients, even before chemotherapy. Comprehension of the cerebral mechanisms related to cognitive impairment in breast cancer patients remains difficult due to the scarcity of studies investigating both cognitive and anatomical imaging changes. Furthermore, only some of the patients experien...
Article
Full-text available
Research into insomnia disorder has pointed to large‐scale brain network dysfunctions. Dynamic functional connectivity is instrumental to cognitive functions but has not been investigated in insomnia disorder. This study assessed between‐network functional connectivity strength and variability in patients with insomnia disorder as compared with mat...
Article
A number of neurotoxicity associated with oncological treatments has been reported in non-central nervous system cancers. An expert group presents the state of the art and a guide to help the choice of appropriated tools to assess patient cognition in studies on oncology and neurobehavior in animal models. In addition, current cognitive rehabilitat...
Article
Full-text available
Background: Breast cancer (BC) is the most frequent cancer in women with more than 70% of BC patients being treated with hormonal therapy (HT). Among these patients, some report difficulties in remembering what they are supposed to do at the right moment, referring to prospective memory (PM). PM is essential for autonomy and medical adherence of p...
Article
Insomnia Disorder (ID) is the second-most common mental disorder and has a far-reaching impact on daytime functioning. A meta-analysis indicates that, of all cognitive domains, declarative memory involving the hippocampus is most affected in insomnia. Hippocampal functioning has consistently been shown to be sensitive to experimental sleep deprivat...
Article
Anses • Bulletin de veille scientifique n° 32 • Santé / Environnement / Travail • Septembre 2017 e70 Conditions psycho-sociales au travail et liens possibles sur les performances cognitives après la retraite Joy PERRIER et Marie Laure BOCCA I perrierjoy@gmail.com Inserm, Comete U1075, Caen Mots clés : Age, déclin cognitif, environnement psychosocia...
Article
The present study mainly aimed to assess whether and how sleepiness due to sleep deprivation interacts with Time on Task (ToT) effects both on electroencephalography (EEG) measures and driving performance in real driving conditions. Healthy participants performed a one hour on-the-road monotonous highway driving task while EEG was recorded continuo...
Chapter
L'utilisation d'un véhicule associé à la consommation de psychotropes relève de pratiques relativement courantes (21% des causes d'accident en 2013 selon l'Observatoire National Interministériel de Sécurité Routière). Les données épidémiologiques et les pourcentages de consommation de médicaments ne permettent pas de faire un lien de causalité dire...
Article
Full-text available
It has been shown that during the planning of a voluntary movement, the transmission of cutaneous afferent inputs to the somatosensory cortex is attenuated shortly before the motor output, as well as during movement execution. However, it is not known if the sensory suppression observed during the planning phase (i.e., before any execution) is a sy...
Article
Full-text available
Insomniacs report decreased performance in daily routines, which may have detrimental consequences for car driving. We compared changes over time in driving performance (measured as Standard Deviation of Lateral Position-SDLP) and background EEG between 20 untreated insomnia patients (52-70 years old) and 21 normal sleepers (54-73 years old) during...
Article
Full-text available
To assess drug induced driving impairment, initial screening is needed. However, no consensus has been reached about which initial screening tools have to be used. The present study aims to determine the ability of a battery of psychometric tests to detect performance impairing effects of clinically relevant levels of drowsiness as induced by one n...
Article
Full-text available
Objective: To assess the specific prefrontal activity in comparison to those in the other main cortical areas in primary insomnia patients and in good sleepers. Methods: Fourteen primary insomnia patients and 11 good sleepers were included in the analysis. Participants completed one night of polysomnography in the sleep lab. Power spectra were c...
Book
L'utilisation d'un Îhicule associé à la consommation de psychotropes relève de pratiques relativement courantes (21% des causes d'accident en 2013 selon l'Observatoire National Interministériel de Sécurité Routière). Les données épidémiologiques et les pourcentages de consommation de médicaments ne permettent pas de faire un lien de causalité direc...
Article
Full-text available
Study objectives: To evaluate driving performance and psychomotor vigilance in patients with primary insomnia. Design: After 1 night of polysomnography, participants performed a 1-h simulated monotonous driving task and a psychomotor vigilance task (PVT). Self-ratings of sleepiness, mood, and driving performance were completed. Setting: This s...
Conference Paper
Introduction Primary insomnia is characterized by complaints of non-restorative and/or insufficient sleep during at least one month in the absence of other pathologies according to the DSM-IV. However, the pathophysiology of insomnia is not well understood. According to a number of studies, primary insomniacs display cortical hyperarousal during wa...
Conference Paper
Introduction Insomnia patients consistently self-reported daytime fatigue and cognitive impairments which could contribute to traffic crashes. However, the model of hyperarousal was proposed to explain the lack of objective evidence of cognitive dysfunction in patients with primary insomnia because of the contribution of psychological and physiolog...
Article
Full-text available
Several studies showed that the transmission of afferent inputs from the periphery to the somatosensory cortex is attenuated during the preparation of voluntary movements. Here, we tested whether sensory attenuation is also observed during the preparation of a voluntary step. It would appear dysfunctional to suppress somatosensory information which...
Article
Full-text available
Est-il dangereux de conduire après une nuit de garde ? Une étude en simulation de conduite S. Arzalier-Daret a, M.-L. Boccaa,∗, J.-N. Amatoa, C. Berthelon b, J. Perrier c, P. Denise a, J.-L. Hanouza a Caen, France b Salon de Provence, France c ERI27, Caen, France Adresse e-mail : bocca-ml@phycog.org (M.-L. Bocca) Introduction.— La somnolence au vol...

Questions

Questions (4)
Question
Dear all,
We would like to investigate mind-wandering in relationship with resting state fMRI. Should we ask participants to keep eyes open or eyes closed ? I could not find a consensus in the litterature.
Any feedback is helpful.
Thanks !
Question
I would like to use Eprime file to import maker in EEG file (Brain Vision). Data in the Eprime files correspond to good and wrong answers and I want to use it for ERPs analysis. Can someone give me some advice?
Question
I want to calculate the alpha/theta ratio for our EEG datas. Do I have to use BrainVision for this or can I do it by myself?
Question
I am analyzing Psychomotor Vigilance Test (PVT) data. Can somebody tell me if I have to include reaction times associated to "laspes" when I calculate the mean reaction time?

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Projects

Projects (5)
Project
The aim of this special issue is to elucidate the impact of sleep and circadian rhythms disturbances associated with cancer and its treatments on quality of life and survivorship issues. We thus welcome submission to reviews, original articles, as well as methodological papers contributing to this topic. For more information, please visit this link: https://www.frontiersin.org/research-topics/20447/sleep-and-circadian-rhythms-in-cancer-patients-and-relationship-with-quality-of-life Extended deadline for submission: 17th of December 2021 Topic Editors: Ali Amidi, PhD, Josée Savard, Prof. Lisa Wu, PhD, Bénédicte Giffard, Prof. Joy Perrier, PhD
Project