Journaux Laurent

France Génétique Elevage

The objective of this study was to better understand the positions of the stakeholders of the livestock sector with respect to the use of genome editing techniques. A qualitative survey by semi-directive interviews was conducted with different actors of the livestock sector. It allowed to establish a typology of stakeholders in five categories (opp...

Les outils de modification du génome sont nombreux et peuvent conduire à des utilisations variées : inactivation, mutation, suppression ou insertion d’un élément d’ADN ou d’un gène dans un organisme. Certaines méthodes induisent une modification aléatoire, tandis que d’autres, qui nous intéressent plus particulièrement, s’effectuent de manière cibl...

Mycobacterium avium subsp. paratuberculosis is the etiological agent of Johne’s disease in ruminants. Here, we report the annotated draft genome sequences of 142 M. avium subsp. paratuberculosis strains that were isolated from dairy cattle in France between 2014 and 2018. The genomes of these strains were sequenced using Illumina technology.

Mycobacterium avium ssp. paratuberculosis (MAP) is the etiological agent of paratuberculosis, a disease that affects ruminants worldwide. Despite global interest in the control of this disease, gaps exist in our knowledge of fecal shedding patterns and concurrent serological patterns. This longitudinal study in dairy cattle herds with high MAP sero...

During the last 15 years, France Génétique Elevage (FGE) has developed a quality management system in compliance with ISO 9001 standard, in process mode, involving more than 180 independent organisations and 6 different professional activities, in the field of cattle genetic improvement. FGE has developed a robust quality system structured with: a...

One of the challenges of the beef industry is the control and prediction of meat tenderness, an important criterion for consumers. This work was aimed at better predicting tenderness based on biochemical muscle characteristics using meta-analysis approaches. For this, we relied on the BIF-Beef database gathering individual data from several researc...

Genomic selection was simulated in a large dairy cattle population in comparison with a breeding scheme based on bull progeny-testing. The maximum increase of genetic gain (about 80% without cost increase) was obtained when bull sires, in much larger number, were selected only based on genomic information, without progeny-testing. In spite of a sho...

Numéro Hors-Série ; Session différenciation de l'offre par la qualitéPartenaires des JSMTV 2014 : Polytech Clermont-Ferrand, France.VetAgro Sup, Institut d'Enseignement Supérieur et de Recherche en Alimentation, Santé Animale, Sciences Agronomiques et de l'Environnement, France.ADIV, Association pour le Développement de l'Institut de la Viande, Fra...

Improving the traits that underlie meat quality is a major challenge in the beef industry. The objective of this paper was to detect QTLs linked to sensory meat quality traits in 3 French beef cattle breeds. We genotyped 1,059, 1,219, and 947 young bulls and their sires belonging to the Charolais, Limousin, and Blonde d'Aquitaine breeds, respective...

La variabilité forte et non maîtrisée de la tendreté de la viande bovine est un problème majeur pourtoute la filière : éleveurs, abatteurs, distributeurs et consommateurs. Actuellement cette qualité, nepeut-être évaluée qu’après abattage par des tests d’analyse sensorielle ou par des mesuresmécaniques. Aussi, les recherches conduites depuis une diz...

Despite massive research efforts, the molecular etiology of bovine polledness and the developmental pathways involved in horn ontogenesis are still poorly understood. In a recent article, we provided evidence for the existence of at least two different alleles at the Polled locus and identified candidate mutations for each of them. None of these mu...

Candidate causative mutations for Cha-PH1 and Hol-PH1 based on whole genome sequencing data. *The duplicated segment differs from the original by two mutations corresponding to g.1909354T>A and g.1909390_1909391del based on the reference sequence. The unique candidate causative mutation for the polled Celtic allele and the five candidate causative...

Distribution of the Celtic and Friesian alleles in a large panel of polled and horned animals. a: Central European horned breeds with polled strain traced back to the beginning of the 19th century. b: Western European breed with polled strain traced back to the end of the 19th century [88]. c: zebu and zebu X taurine African breeds. (DOC)

Details on primers used in this study. (DOC)

Multispecies alignment of genomic sequences encompassing the Celtic mutation in Bovidae and non-Bovidae ruminant species. Bta: Bos taurus (cattle, wild-type allele), Bbi: Bison bison (American bison), Bbu: Bubalus Bubalis (water buffalo), Btr: Boselaphus tragocamelus (Nilgai), Ace: Antilope cervicapra (blackbuck antelope), Cae: Capra aegagrus (wild...

Details of the abnormal prepuce withdrawal phenotype displayed by some polled bulls. Genital tracts of a horned Charolais bull (A) and of two PC/p Charolais bulls during penis withdrawal. (TIF)

Details of animals and designs used in the different experiments. Breed abbreviations: AAN: Aberdeen-Angus, ABO: Abondance, AUB: Aubrac, BAQ: Blonde d’Aquitaine, BAZ: Bazadaise, BSW: Brown Swiss, CHA: Charolais, FJL: Fjäll, FSI: French Simmental, GAN: German Angus, GAS: Gasconne, GFV: German Fleckvieh, GLW: Galloway, HOL: Holstein, ICL: Icelandic C...

Information on sequences replacing the UMD3.1 genome assembly gaps within the Friesian interval. (DOC)

The BIF-Beef (Beef Integrated and Functional Biology) database contains animal, carcass, muscle and meat data (331,745 entries) collected from 43 experiments over the last 20 years and a great number of variables (621) characterising muscles (fat and collagen contents, cross-section and types of fibres, metabolic activity), making it a relevant too...

To study the beef meat quality traits at the molecular level and find genetic markers associated to these traits, the project “Qualvigène” was set in. A total of 1,059 Charolais, 1,219 Limousin and 947 Blond d’Aquitaine purebred young bulls from respectively 48, 36 and 30 sire families were genotyped with the Illumina Bovine SNP50® Beadchip. We mea...

The BIF-Beef (Beef Integrated and Functional Biology) database contains animal, carcass, muscle and meat data (331,745 entries) collected from 43 experiments over the last 20 years and a great number of variables (621) characterising muscles (fat and collagen contents, cross-section and types of fibres, metabolic activity), making it a relevant too...

In order to identify new markers of beef tenderness, a proteomic analysis was performed on Longissimus thoracis muscle to compare two extreme groups in terms of meat tenderness, consisting of 10 animals each of the three main French beef breeds: Blond d’Aquitaine, Charolais, and Limousin. Animals were grouped on the basis of an index combining a te...

Un des enjeux de la filière bovine est la maîtrise et la prédiction de la tendreté de la viande, critère important pour les consommateurs. Ce travail avait pour objectif de mieux prédire la tendreté par méta-analyse à partir des caractéristiques biochimiques du muscle. Pour cela, nous nous sommes appuyés sur la base de données BIF-Beef regroupant d...

Background An important controversy in the relationship between beef tenderness and muscle characteristics including biochemical traits exists among meat researchers. The aim of this study is to explain variability in meat tenderness using muscle characteristics and biochemical traits available in the Integrated and Functional Biology of Beef (BIF-...

Without routine measurement of sensory meat quality traits , breeding companies wonder how to take advantage of the genetic variability of these traits at the molecular level. The projects “Qualvigène” and “Qualvigène + ABQV” were set in to find markers associated to beef quality therefore. A total of 1,059 Charolais, 1,219 Limousin and 947 Blond d...

Beef is characterized by a high and uncontrolled variability of its palatability, which is one reason for consumer dissatisfaction. In Europe, there is still no reliable tool to predict beef quality to deliver consistent quality beef to consumer. Faced to the number of factors influencing beef quality, scientists and professional partners of the Pr...

This study used the BIF-Beef data warehouse to determine whether semitendinosus (ST) was a muscle with a faster contraction speed and more glycolytic than longissimus thoracis (LT), regardless of the sex and breed of animals. With more than 500 animals from 7 breeds, we confirmed that LT was more oxidative than ST in males and females, but not in s...

Genomic selection is implemented in French Holstein, Montbéliarde, and Normande breeds (70%, 16% and 12% of French dairy cows). A characteristic of the model for genomic evaluation is the use of haplotypes instead of single-nucleotide polymorphisms (SNPs), so as to maximise linkage disequilibrium between markers and quantitative trait loci (QTLs)....

Background: An important controversy in the relationship between beef tenderness and muscle characteristics including biochemical traits exists among meat researchers. The aim of this study is to explain variability in meat tenderness using muscle characteristics and biochemical traits available in the Integrated and Functional Biology of Beef (BI...

Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access

Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access

The objectives of the study were to evaluate allelic frequencies and to test the association of polymorphisms in the calpastatin (CAST) and µ-calpain (CAPN1) genes with meat tenderness in 3 French beef breeds. A total of 1,114 Charolais, 1,254 Limousin, and 981 Blonde d'Aquitaine purebred young bulls were genotyped for 3 SNP in the CAST gene and 4...

Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access

1 page Diffusion du document : Abstracts"Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access "

Cet article présente une simulation de sélection génomique dans une grande population de bovins laitiers en comparaison à un programme basé sur le testage des taureaux sur descendance. L’accroissement de progrès génétique est maximum (au moins 80% sans augmentation de coût) quand les pères à taureaux, dont les effectifs sont en forte augmentation,...

Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access

The availability of genetic tests to detect different mutations in the myostatin gene allows the identification of heterozygous animals and would warrant the superiority of these animals for slaughter performance if this superiority is confirmed. Thus, 2 mutations of this gene, Q204X and nt821, were studied in 3 French beef breeds in the program Qu...

Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access

The first international joint genetic evaluation between France, Ireland and United Kingdom for pure bred Limousin weaning weights offers the opportunity to review the Interbeef story and detail the different steps to achieve before implementing a common genetic evaluation for beef cattle. This study along with the previous EUBEEVAL works reveals t...

*INRA SAGA BP27 31326 Castanet-tolosan Cedex Diffusion du document : INRA SAGA BP27 31326 Castanet-tolosan Cedex

Compte rendu 2597*INRA, Centre de Jouy Diffusion du document : INRA, Centre de Jouy

*INRA, Centre de Jouy Diffusion du document : INRA, Centre de Jouy

Compte rendu 2482*INRA, Centre de Jouy Diffusion du document : INRA, Centre de Jouy

Summary We can discribe 3 principal steps in the recent development of international genetic evaluation in beef cattle. At the beginnings of the 90's the first attempts were multi-countries genetic evaluation of close countries using a single model without country effect. In 1999 the Irish initiative named EUBEEVAL provided a Frame to study the bes...

Weaning weights of Limousine calves recorded in France (n=1439088), Luxemburg (n=13175) and Ireland (n=7041) were analyzed. First, the connectedness level across these three countries was shown to be satisfactory. Within and across-country genetic parameter REML estimations were ran with a multivariate animal model. Direct heritabilities vary from...

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