Jouni J.K. Jaakkola

Jouni J.K. Jaakkola
University of Oulu · Center for Environmental and Respiratory Health Research (CERH)

MD, DSc, PhD

About

257
Publications
60,879
Reads
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15,435
Citations
Citations since 2017
19 Research Items
4810 Citations
20172018201920202021202220230200400600800
20172018201920202021202220230200400600800
20172018201920202021202220230200400600800
20172018201920202021202220230200400600800
Additional affiliations
November 2008 - present
University of Oulu
Position
  • Managing Director
May 2003 - August 2008
University of Birmingham
Position
  • Managing Director
April 2000 - April 2003
Nordic School of Public Health
Position
  • Professor of Public Health

Publications

Publications (257)
Preprint
Background: Previous inconsistent evidence on effects of green space on the development of allergic rhinitis could be explained by the season of exposure. We explored whether the season and timing of exposure to green space play a role in the development of allergic rhinitis during the first 27 years of life. Methods: In a longitudinal study of 256...
Article
Background and aim The associations between COVID-19 transmission and meteorological factors are scientifically debated. Several studies have been conducted worldwide, with inconsistent findings. However, often these studies had methodological issues, e.g., did not exclude important confounding factors, or had limited geographic or temporal resolut...
Preprint
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Background: Identifying how greenspace impacts the temperature-mortality relationship in urban environments is crucial, especially given climate change and rapid urbanization. To date, studies on this topic have indicated conflicting findings and typically focus on a localized area or single country. We evaluated the effect modification of greenspa...
Preprint
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There is accumulating evidence that prenatal exposure to air pollution disturbs fetal growth and development, but little is known about these effects in cold climates or their season-specific or joint effects. Our objective was to assess independent and joint effects of prenatal exposure to specific air pollutants on the risk of low birth weight (L...
Article
This study determined the association of cold-related symptoms with workplace temperature and thermal insulation of clothing among Thai chicken industry workers. Three hundred workers were interviewed regarding cold-related symptoms, which were regressed on worksite temperature and protective clothing. In total, 80% of workers reported respiratory...
Article
Purpose: We summarized the evidence on the effects of heat and cold exposures on mortality in China. We included studies published on this topic in both Chinese and English, thereby filling a gap in knowledge using data from a country that consists of one-fifth of the world's population. Methods: We conducted a systematic search of peer-reviewed...
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Background: The health burden associated with temperature is expected to increase due to a warming climate. Populations living in cities are likely to be particularly at risk, but the role of urban characteristics in modifying the direct effects of temperature on health is still unclear. In this contribution, we used a multi-country dataset to stud...
Article
Introduction: Phthalate exposure may reduce intellectual development in young children. In 2011, numerous Taiwanese children had been reported to have consumed phthalate-tainted products. We investigated the effects of phthalate exposure on the intellectual development of these children after the 2011 Taiwan di-2-ethylhexyl phthalate (DEHP) episod...
Article
Background: China's rapid economic development has resulted in severe particulate matter (PM) air pollution and the control and prevention of infectious disease is an ongoing priority. This study examined the relationships between short-term exposure to ambient particles with aerodynamic diameter ≤2.5µm (PM2.5) and measles incidence in China. Met...
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Sudden cardiac death (SCD) is the leading cause of death. The current paradigm in SCD requires the presence of an abnormal myocardial substrate and an internal or external transient factor that triggers cardiac arrest. Based on prior mechanistic evidence, we hypothesized that an unusually cold weather event (a cold spell) could act as an external f...
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Background Asthma subtyping is a complex new field of study. Usually both etiological and outcome factors of asthma have been used simultaneously for subtyping thus making the interpretation of the results difficult. Identification of subtypes of asthma based on questionnaire data only will be useful for both treatment of asthma and for research. O...
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Early-life respiratory tract infections (RTIs) and dental caries are among the most common infectious diseases worldwide. The relations between early RTIs and development of caries in permanent teeth have not been studied earlier. We assessed childhood RTIs as potential predictors of caries in young adulthood in a 20-year prospective population-bas...
Article
The prevalence of heat-related cardiorespiratory symptoms among vulnerable groups is not well known. We therefore estimated the prevalence of heat-related cardiorespiratory symptoms among the Finnish population and their associations with social and individual vulnerability factors. The data came from the National FINRISK 2007 Study, in which 4007...
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Abstract: Both temperature and humidity may independently or jointly contribute to the risk of human rhinovirus (HRV) infections, either through altered survival and spread of viruses in the environment or due to changes in host susceptibility. This study examined the relationship between short-term variations in temperature and humidity and the ri...
Article
Uncontrolled urbanization in developing countries has led to widespread urban poverty and increased susceptibility to environmental exposures owing to the hazardous occupational activities of the urban poor. Street vending and waste picking are the dominant works undertaken by the urban poor, and besides the physical hazards, it also exposes them t...
Article
Aims: To examine the seasonality and effects of temperature on levels of fasting plasma glucose (FPG). Methods: We collected health data from the Kailuan cohort study. FPG, blood pressure and individual information including age, gender, body mass index, smoking status, drinking habit, physical activities, income, work type, education level, and...
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Previous epidemiologic studies have assessed the role of the exposure to ambient air pollution in the development of cardiac birth defects, but they have provided somewhat inconsistent results. To assess the associations between exposure to ambient air pollutants and the risk of cardiac defects, a population-based case-control study was conducted u...
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Previous studies have provided contradictory evidence on the role of early childhood respiratory infections in the development of asthma and other allergic diseases during childhood. We investigated early-life respiratory infections as predictors of the development of asthma in a 20-year prospective cohort study (the Espoo Cohort Study, 1991–2011)....
Article
Background: IL33 is an important cytokine in the pathogenesis of asthma, and associations of IL33 gene polymorphisms with asthma have been suggested by several genome-wide analyses. However there are no studies regarding the association of IL33 with adult-onset asthma. Objective: To investigate if IL33 single-nucleotide polymorphisms (SNPs) associ...
Article
Background: There are only few studies on subtypes of asthma among adult asthmatics based on clustering methods. Even fewer studies elaborated the effects of current smoking on asthma subtypes defined by variables of asthma control. Objectives: We investigated statistically the subtypes of asthma among 1995 17-73 year-old asthmatics from the Northe...
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Exposure to perfluorooctane sulfonic acid (PFOS) or to perfluorooctanoic acid (PFOA) increases mouse and human PPARα subtype activity which influences lipid metabolism. Because cholesterol is the substrate from which testosterone is synthesized exposure to these substances has the potential to alter testosterone concentrations. Explore associations...
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There is substantial evidence that mortality increases in low temperatures. Less is known about the role of prolonged cold periods denoted as cold spells. We conducted the first systematic review and meta-analysis to summarize the evidence on the adverse health effects of cold spells in varying climates. Four databases [Ovid Medline, PubMed, Scopus...
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Previous studies have shown that phthalate exposure in childhood is associated with the development of respiratory problems. However, few studies have assessed the relative impact of prenatal and postnatal exposure to phthalates on the development of asthma later in childhood. Therefore, we assessed the impact of prenatal and postnatal phthalate ex...
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Physiological calibration (Physiocal) improves the quality of continuous blood pressure (BP) signal from finger. However, the effects of Physiocal on spectral characteristics of systolic BP (SBP) variability are not well-known. We tested the hypothesis that the use of Physiocal may alter the results on SBP variability when compared with BP recordin...
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About 41% of households globally, mainly in developing countries rely on solid fuels for cooking with consequences for fetal growth and development. Previous reviews were limited in scope, assessing only two outcomes (birth weight, stillbirth). With important evidence accumulating, there is a need to improve the previous estimates and assess additi...
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Background Family history of asthma and other allergic diseases have been linked to the risk of childhood asthma previously, but little is known about their effect on the age-of-onset and persistency of asthma until young adulthood.Methods We assessed the effect of the family history of asthma and allergic diseases on persistent vs. transient, and...
Chapter
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This chapter describes the importance of housing in the context of climate change and the health effects of climate change. The contribution of housing life cycle to production of greenhouse gases (GHGs), and the association between climate change, housing dampness, mould problems and respiratory health are discussed. The impact of housing-related...
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Encouraging individuals to take action is important for the overall success of climate change mitigation. Campaigns promoting climate change mitigation could address particular groups of the population on the basis of what kind of mitigation actions the group is already taking. To increase the knowledge of such groups performing similar mitigation...
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Bayesian statistical inference with a case-crossover design was used to examine the effects of air pollutants {Particulate matter <10 μm in aerodynamic diameter (PM10), sulphur dioxide (SO2), and ozone (O3)} on mortality. We found that all air pollutants had significant short-term impacts on non-accidental mortality. An increase of 10 μg/m(3) in PM...
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Objectives: The aim of our study was to assess the effect of short-term cold exposure, typical in subarctic climate, on cardiac electrical function among untreated middle-aged hypertensive men. Methods: We conducted a population-based recruitment of 51 hypertensive men and a control group of 32 men without hypertension (age 55-65 years) who unde...
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Climate change is a major public health threat that is exacerbated by food production. Food items differ substantially in the amount of greenhouse gases their production generates and therefore individuals, if willing, can mitigate climate change through dietary choices. We conducted a population-based cross-sectional study to assess if the underst...
Article
Background Indoor mold exposure is common worldwide and constitutes an important health problem. There are very few studies assessing the relation between mold exposure and lung function levels among non-asthmatic adults. Our objective was to assess the relations between dampness and mold exposures at home and at work and lung function. We elaborat...
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Little evidence is available about the association between temperature and cerebrovascular mortality in China. This study aims to examine the effects of ambient temperature on cerebrovascular mortality in different climatic zones in China. We obtained daily data on weather conditions, air pollution and cerebrovascular deaths from five cities (Beiji...
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Both temperature and humidity may independently or jointly contribute to the risk of influenza infections. We examined the relations between the level and decrease of temperature, humidity and the risk of influenza A and B virus infections in a subarctic climate. We conducted a case-crossover study among military conscripts (n = 892) seeking medica...
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The epidemiological evidence linking socioeconomic deprivation with adverse pregnancy outcomes has been conflicting mainly due to poor measurement of socioeconomic status (SES). Studies have also failed to evaluate the plausible pathways through which socioeconomic disadvantage impacts on pregnancy outcomes. We investigated the importance of matern...
Article
The occurrence of cold temperature-related symptoms has not been investigated previously in young adults, although cold weather may provoke severe symptoms leading to activity limitations, and those with pre-existing respiratory conditions may form a susceptible group. We tested the hypothesis that young adults with asthma and allergic rhinitis exp...
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The occurrence of subjective symptoms related to heat strain in the general population is unknown. The present study aimed to describe the temperatures considered to be comfortable or hot and the prevalence of heat-related complaints and symptoms in the Finnish population. Four thousand and seven men and women aged 25-74 years, participants of the...
Article
A substantial proportion of the world's population is exposed to indoor dampness-related exposures. Since the 1990s, studies have assessed the relation between indoor dampness and mold and rhinitis, but the evidence has been inconclusive. No previous meta-analysis has been reported on this topic. We conducted a systematic review and meta-analysis o...
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Rationale: Identification of the subpopulation especially susceptible to the adverse effects of second-hand smoke exposure (SHS) would be useful for preventive actions and interventions. Objectives: To investigate whether asthmatic heredity indicates susceptibility to the effects of SHS on the risk of adult-onset asthma. Methods: A population-...
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Short- and long-term exposures to cold increase blood pressure and may explain the higher wintertime cardiovascular morbidity and mortality. Hypertensive subjects may be more susceptible to adverse cold-related cardiovascular health effects. The aim of our study was to assess the effect of short-term cold exposure on central aortic blood pressure a...
Article
Street vending, a dominant occupation in urban areas of developing countries exposes the vendors to several environmental pollutants. We investigated whether work as street vendor impairs foetal growth and shortens gestational duration, and evaluated to what extent exposure to traffic-related air pollution is responsible for these adverse effects....
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Atopic diseases, including allergic rhinitis, allergic dermatitis and asthma, are common diseases with a prevalence of 30-40% worldwide and are thus of great global public health importance. Allergic inflammation may influence the immunity against infections, so atopic individuals could be susceptible to respiratory infections. No previous populati...
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Exposure to cold weather increases blood pressure (BP) and may aggravate the symptoms and influence the prognosis of subjects with a diagnosis of hypertension. We tested the hypothesis that subjects with hypertension alone or in combination with another cardiovascular disease (CVD) experience cold-related cardiorespiratory symptoms more commonly th...
Article
Background Seasonal variation in the occurrence of birth defects provides indirect evidence of the causal role of environmental factors, because genetic factors do not exhibit seasonality.AimThis study was undertaken to assess the seasonal variation of birth defects in Norway.Methods We conducted a nationwide cross-sectional study of 326,560 births...
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Background: Disregard of Hippocratic medical ethics by major leaders in the Public Health establishment and the leadership role played by physicians during the Nazi era in Germany (1933-1945) pose continuing challenges for later generations to investigate and disclose. Aims: We review the history of evolution from humiliation of mental patients, ot...
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Objective To examine the effects of extremely cold and hot temperatures on ischaemic heart disease (IHD) mortality in five cities (Beijing, Tianjin, Shanghai, Wuhan and Guangzhou) in China; and to examine the time relationships between cold and hot temperatures and IHD mortality for each city. Design A negative binomial regression model combined wi...
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Context: Studies from different geographical regions have assessed the relations between indoor dampness and mold problems and the risk of asthma, but the evidence has been inconclusive. Objective: To assess the relations between indicators of indoor dampness and mold problems and the risk of developing new asthma, and to investigate whether suc...
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Background Effect of indoor air pollution (IAP) on birth weight remains largely unexplored but yet purported as the most important environmental exposure for pregnant women in developing countries due to the effects of second-hand smoke. We investigated the associations between the determinants of indoor air quality in households and birth weight....
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This study was carried out to examine the association between exposure to polycyclic aromatic hydrocarbon with traffic exhaust and biomarkers of lipid peroxidation and antioxidant levels among highway toll station workers. We conducted a cross-sectional study of 47 female highway toll station workers exposed to traffic exhausts and 27 female classr...
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Pesticide poisoning is an important public health problem worldwide. The study aimed to determine the risk of all-cause and cause-specific inpatient mortality and to identify prognostic factors for inpatient mortality associated with unintentional insecticide and herbicide pesticide poisonings. We performed a retrospective cohort study of 3,986 inp...
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Cooking oil fumes (COF) contain polycyclic aromatic hydrocarbons (PAHs), heterocyclic aromatic amines, benzene, and formaldehyde, which may cause oxidative damages to DNA and lipids. We assessed the relations between exposure to COF and subsequent oxidative DNA damage and lipid peroxidation among military cooks and office-based soldiers. The study...
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Background Many studies have examined the association between ambient temperature and mortality. However, less evidence is available on the temperature effects on coronary heart disease (CHD) mortality, especially in China. In this study, we examined the relationship between ambient temperature and CHD mortality in Beijing, China during 2000 to 201...