Joseph Omorogiuwa Erhabor

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• Ph.D (Phytomedicine)
• Associate Professor at University of Benin

Cannabis sativa has been used in local medicine to manage cancer, ache, inflammation, diabetes, and other conditions. The aqueous extract of Cannabis sativa leaves collected from two geographical locations (South Africa, EC and Lesotho, LS) was assessed for their potential against angiogenesis, nitric oxide (NO) production, oxidative stress and cyt...

Bovine mastitis, caused mostly by Staphylococcus species, has gained global importance owing to the increasing prevalence of multi-drug resistant bacteria, which comprise a risk to food security and public health. In this study, the antibacterial, anti-biofilm and quorum quenching activities of six leaf extracts of Combretum molle R.Br. ex G. Don p...

Histopathology is an essential tool in assessing the untoward effect of toxicants, synthetic drugs, and herbal medicines in toxicological animal studies. Therefore, the effect of the oral administration of graded doses of the ethanol extract of A. barbadensis root on the histology and organ-body weight ratios of some vital rat organs was evaluated....

Nearly all nations in the globe have been impacted by COVID-19, otherwise known as coronavirus infection brought on by new SARS-Cov-2, which has been dubbed a global pandemic. Contact with sick people and handling contaminated surfaces are the main ways that coronavirus is disseminated. However, as of July 2020, it had impacted more than 33 million...

Bacterial biofilms pose health challenges both in clinical environments and the food industry. Major foodborne bacterial pathogens form biofilms on surfaces and persist, causing infections in humans that may be difficult to treat. Conventional use of antibiotics is fast becoming ineffective due to emerging resistance of pathogens to antibiotics. Pr...

Croton gratissimus Burch. is a deciduous shrub used in traditional medicines and a local traditional herbal tea in South Africa. C. gratissimus is used in treating several disease conditions, including cough, influenza, colds, malaria, fever, bleeding gums, chest complaints, indigestion, skin inflammation, earache, respiratory disorders, diabetes,...

Background: This study comparatively assessed seven indigenous traditional tea plants on several attributes that included antioxidant, nutritional, caffeine contents, and cyclooxygenase activity. Methodology: Nutritional content of all tea plants were determined for energy, fat, carbohydrates, total sugars, dietary fiber and amino acids. Antioxidan...

Ethnopharmacological relevance: Cannabis sativa L. is among numerous medicinal plants widely used in traditional medicine in treating various ailments including kidney diseases. Aims: The protective effect of C. sativa on oxidative stress, cholinergic and purinergic dysfunctions, and dysregulated glucogenic activities were investigated in oxidative...

This paper is a review of the application, relevance, advances and achievements of biotechnology in phytomedicine research and development. It also gave insight on the specific role of various biotechnological tools such as micropropagation, somatic embryogenesis, callus mediated organogenesis, cryopreservation, the bioreactor system, combinatorial...

Prostate cancer is one of the major causes of cancer-related deaths among men globally. Medicinal plants have been explored as alternative treatment options. Herein, we assessed the in vitro cytotoxic effects of 70% ethanolic root extracts of six-month-old micropropagated Prunus africana (PIR) on PC-3 prostate cancer cells as an alternative to the...

Foodborne pathogens are a major cause of concern as they are responsible for food spoilage or microbial diseases, leading to economic loss to the food industry as well as health issues. The problem of increased resistance to available antimicrobial agents, and the ability of the microorganisms to form protective biofilms, strengthens their capacity...

Foodborne pathogens are a major cause of concern as they are responsible for food spoilage or microbial diseases, leading to economic loss to the food industry as well as health issues. The problem of increased resistance to available antimicrobial agents, and the ability of the microorganisms to form protective biofilms, strengthens their capacity...

Foodborne pathogens are a major cause of concern as they are responsible for food spoilage or microbial diseases, leading to economic loss to the food industry as well as health issues. The problem of increased resistance to available antimicrobial agents, and the ability of the microorganisms to form protective biofilms, strengthens their capacity...

Background Man has a long history of utilizing herbal preparations to treat infections. Therefore, this study aimed to investigate the quantitative phytochemical components, gas chromatography–mass spectrometry analysis, and the antibacterial properties of the aqueous and ethanol leaf extracts of Moringa oleifera on some clinical bacterial isolates...

Metabolite profiling of cancer cells presents many opportunities for anticancer drug discovery. The Chinese, Indian, and African flora, in particular, offers a diverse source of anticancer therapeutics as documented in traditional folklores. In-depth scientific information relating to mechanisms of action, quality control, and safety profile will p...

The therapeutic potentials of Cannabis sativa L. on oxidative-induced testicular dysfunction were investigated in isolated testes of male albino rats. C. sativa leaves were subjected to sequential extraction to yield the hexane, dichloromethane (DCM), and ethanol extracts. Oxidative injury was induced by incubating testicular tissue homogenate with...

Ethnopharmacological relevance Combretum species are used traditionally for the treatment of diarrhea, hookworm, fever, inflammation, pain and infectious diseases. Infections are commonly caused by the intake of food contaminated with foodborne pathogens. These are a significant concern in the food industry owing to their ability to form biofilms a...

Background Annona muricata L. was identified as a popular medicinal plant in treatment regimens among cancer patients in Jamaica by a previously conducted structured questionnaire. Ethnomedically used plant parts, were examined in this study against human prostate cancer cells for the first time and mechanisms of action elucidated for the most pote...

This study investigated the effect of Chromolaena odorata aqueous leaf extract on the biochemical and haematogical parameters in Wister albino rat and the safest dose level for a prolong administration (21 days) of the doses of 700 mg/kg, 1400 mg/kg and 2100 mg/kg body weight. The extract was administered orally and the procedures outlined in the u...

This study evaluated the in vitro antibacterial, antioxidant, nutritional and cytogenotoxic potentials of Aloe barbadensis (AB) root extract. The antimicrobial activity of AB was determined using agar well diffusion and microdilution techniques while the nutritional analyses were done using standard procedures. The antioxidant activities were evalu...

Bauhinia galpinii is one of several plant species native to South Africa that has been reported to be used traditionally to manage ailments including gastrointestinal disorders, infectious diseases and inflammation. This study was designed to evaluate the in vitro antibacterial, antifungal, antioxidant, cytotoxicity and anti-inflammatory activities...

Background: Microbial infection of the genital tract or semen is one of the leading causes of male infertility. Consequently, there is a need to seek alternative products from natural sources. Objectives: The antibacterial, phytochemical and cytogenotoxicological assessments of the aqueous extract of Cymbopogon citratus leaf were evaluated. Met...

Microbial biofilm and quorum sensing are two intertwined traits that have been used by microorganisms for their survival and improved virulence. They have been implicated as the cause of severe infections in humans as their incidence makes it difficult to treat common infections and the possibility of recurrent infections is high. Microbial biofilm...

Ethnoveterinary medicine (EVM), although not documented well, still serves as an alternative or complementary medication for curing or preventing bacterial, fungal and helminth diseases, as well as other maladies such as ticks and tick-borne diseases in South Africa. The aim of this study was to document plant species used as EVM by the Mnisi commu...

Physostigma venenosum Balf. known as calabar beans (Fabaceae family) is a very poisonous plant with reported therapeutic properties. Many studies have shown its use in medicine for eye problems, glaucoma, constipation, epilepsy, cholera, hypertension and tetanus. In this study, quantitative phytochemistry, proximate analysis and mineral constituent...

The phytochemical screening and antibacterial activity of the acetone root extract of Aloe vera were investigated in this study. Different concentrations (200 mg/ml, 100 mg/ml and 50 mg/ml) were prepared and tested against seven different bacterial isolates which included Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas...

Background Aloe barbadensis (AB) is a short stemmed succulent medicinal herb that is being used by locals in Nigeria to enhance libido. Therefore this study evaluates the aphrodisiac potential and acute toxicological effect of A. barbadensis (AB) root in male Wistar rats. Methods Aphrodisiac potential was determined following the oral administrati...

Seeds of Physostigma venenosum (Balf.), used in traditional medicine for the treatment of glaucoma, Alzheimer’s disease, delayed gastric emptying and acute tetanus, underwent an extraction process by way of maceration and evaporation in ethanol. The 16 Wister rats of either sex were weighed and placed into four groups of four animals per group. Gra...

The antimicrobial activities and phytochemical constituents of aqueous and hexane extracts of both the bark and roots of Dennettia tripetala F. Baker (Annonaceae) were determined using routine methods. Flavonoids, saponins, phenolic compounds, volatile oil, carbohydrate and reducing sugars were present in the aqueous extract of the root and bark, b...

Ethnopharmacological relevance: The present study entails the medicinal plant species used to manage sickle cell disorder in Southern States of Nigeria. Materials and methods: The ethnomedicinal information was gathered through multistage approach from three geopolitical zones of Southern Nigeria, which were purposively selected. Semi-structured...

Khaya senegalensis seed oil is a non-drying oil, which consist of long chain fatty acids. The antimicrobial attributes of the seed oil was investigated using disc diffusion and broth dilution methods. The test microbial cultures used in the study were; Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albic...

Market survey was conducted in five markets (uselu, New Benin, Oba, Oliha and Lagos Street) in Benin City, Nigeria. Fifty medicinal plants used for the cure of various ailments (including malaria, stomach disorder, skin infection, dysentery, cough, constipation, veneral diseases, and also as anthelminthic and purgatives) were documented. Heavy meta...

The use of medicinal plants had increased significantly in the last one decade in Nigeria but linked with bogus claims. The microbial quality of 15 medicinal plants randomly selected from 50 medicinal plants obtained from five local markets in Benin City, Edo State, Nigeria was ascertained in this study. The pour plate method was used to cultivate...

This study presents investigations into the epidermal and phytochemical features of Eragrostis tremula (S.W.Beauv.), Cymbopogon citratus (Stapf.) and Axonopus compressus.(P.Beauv.). Epidermal features of the different species in the three genera showed slight differences for both the adaxial and abaxial parts with respect to prickles, papillae, mac...

Purpose: To evaluate the microbial load on 17 randomly selected plant samples from 60 ethnobotanically collected medicinal plants from five local markets in Abeokuta, Ogun State, Nigeria. Method: The pour plate method was used to cultivate serially diluted portions of the medicinal plant samples investigated. Enumeration of bacteria was carried out...

Purpose: To document the medicinal values, local names, method of preparation, dosage forms and parts of common medicinal plants sold in some markets in Abeokuta, Nigeria. Methods: Ethnobotanical data were collected by oral interview and with the aid of a structured questionnaire administered to men, women and young girls. The data from respondents...

A comparative study of the morphological and anatomical features of the leaves and stems of Stachytarphetajamaicensis and S. cayennensis was undertaken; both species have been widely reported in several herbal medicines. The presence of angular stem and pubescent leaves in the latter distinguishes it morphologically from the former, which is charac...

The study reports oral information on the ethnomedicinal uses of plant remedies in traditional health-care among Otuo tribe of Edo State, Nigeria. Records of 51 plant species belonging to 47 genera of 34 families are presented with their local names, parts used, preparations, modes of administration, dosage and uses.