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Jose Luis González-Carrasco

Jose Luis González-Carrasco
Centro Nacional de Investigaciones Metalúrgicas (CENIM), Madrid, Spain · Physical Metallurgy

Dr

About

176
Publications
17,694
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2,714
Citations
Additional affiliations
January 1990 - present
Spanish National Research Council
Position
  • Development of metallic bomaterials and their coatings
September 1975 - present
Centro Nacional de Investigaciones Metalúrgicas (CENIM)
Position
  • Senior Researcher
Education
January 1984 - September 1987
Complutense University of Madrid
Field of study
  • High Temperature Alloys
September 1970 - July 1975
Complutense University of Madrid
Field of study
  • Ciencias Químicas

Publications

Publications (176)
Conference Paper
Full-text available
Laser peening has recently emerged as a useful technique to overcome detrimental effects associated to another wellknown surface modification processes such as shot peening or grit blasting used in the biomedical field. It is worth to notice that besides the primary residual stress effect, thermally induced effects might also cause subtle surface a...
Article
Full-text available
Grit blasting is a surface treatment process widely used to enhance mechanical fixation of the implants through increasing their roughness. Test samples of two metallic biomaterial alloys such 316LVM and Ti6Al4V were blasted by projecting Al2O3 and ZrO2 particles which yield a coarse and a fine rough surface. Then, the blasted samples were thermall...
Article
Grit blasting is used as a cost-effective method to increase the surface roughness of metallic biomaterials, as Ti6Al4V and 316 LVM, to enhance the osteointegration, fixation and stability of implants. Samples of these two alloys were blasted by using alumina and zirconia particles, yielding rough (up to Ra~8μm) and nearly smooth (up to Ra~1μm) sur...
Article
Grit blasting is a surface plastic deformation technique aimed to increase the surface area available for bone/implant apposition, which contributes to improve fixation and mechanical stability of Ti-6Al-4V implants. Besides roughening, grit blasting also causes surface contamination with embedded grit particles and subtle subsurface microstructura...
Article
The purpose of this work is to study the elastoplastic properties of novel intermetallic coatings grown by hot dipping on medical steel 316 LVM and their correlation with the scratch resistance by means of instrumented ultramicroindentation techniques. Elastoplastic properties are defined by the plasticity index (PI), which correlates the hardness...
Article
Full-text available
Polylactic acid (PLA) is a semi-crystalline biopolymer with numerous applications in tissue engineering and regenerative medicine. PLA biodegradable devices are usually manufactured by extrusion or injection molding. The crystalline-amorphous structure that PLA acquires during processing is relevant for its applications as it determines the biodegr...
Article
Full-text available
In the last few decades, the development of new electrospun materials with different morphologies and advanced multifunctional properties are strongly consolidated. There are several reviews that describe the processing, use and characterization of electrospun nanocomposites, however, based on our knowledge, no review on electrospun nanocomposites...
Article
Laser shock processing (LSP) is increasingly applied as an effective technology for improving the properties of different metallic components. This is done principally to enhance their corrosion and fatigue life behaviour, stress corrosion cracking resistance, etc. In this paper, LSP has been applied to a commercially pure Mg and a Mg-1Zn alloy (wt...
Article
The aim of this paper is to investigate the evolution of a matrix-filler interface during the processing of novel composites formed by a matrix of polylactic acid (PLA) and Mg particles, when they are manufactured by Materials Extrusion. The particles addition to the PLA was carried out through the preparation of a Magnesium stable suspension in th...
Article
PLA/Mg composites have been successfully proposed as biodegradable and fully bioabsorbable materials for bone repair. The present work claims the benefits of Mg particles modification throughout the adsorption of surface modifiers in the in vitro biodegradation behavior of PLA/Mg composites. Additionally, the mixture of PLA with Mg particles in a c...
Article
New biocompatible and bioabsorbable materials are currently being developed for bone regeneration. These serve as scaffolding for controlled drug release and prevent bacterial infections. Films of polylactic acid (PLA) polymers that are Mg-reinforced have demonstrated they have suitable properties and bioactive behavior for promoting the osseointeg...
Article
During recent years, Mg reinforced polylactic acid (PLA) composites have emerged as potential biocompatible and bioabsorbable materials for biomedical applications. It has been shown that Mg particles added to a matrix based on a biodegradable polymer can address the lack of bioactivity and the low mechanical properties of the polymers and, further...
Article
Ti6Al4V ELI alloy is widely used for the fabrication of a wide range of load-bearing implants. Surface modification by laser shock processing (LSP) has demonstrated the capability to generate roughness of clinical interest, being the control of the surface and subsurface microstructural changes relevant to the intended applications. This work is ai...
Article
A deeper knowledge on the degradation pattern of a biodegradable material is required before considering it for a specific application as a bioabsorbable implant. In the last few years, composites formed by polylactic-acid reinforced with Mg-based particles have been proposed for biodegradable implants. The aim of the present work is to study the e...
Article
Laser shock processing (LSP) is increasingly applied as an effective technology for the improvement of metallic materials’ mechanical and surface properties in different types of components, mostly as a means of enhancement of their fatigue life behavior. As reported in previous contributions by the authors, a main effect resulting from the applica...
Article
Full-text available
Objective: The aim of this study was to assess the degradation behavior by measuring the H2 release of a biodegradable composite consisting of a polylactic acid matrix reinforced with 30% wt. spherical magnesium microparticles (PLA/Mg) as potential bone augmentation material in combination with dental implants of either titanium or polyetheretherk...
Chapter
The development of new materials for biodegradable and bioabsorbable implants in bone repair seeks to overcome the disadvantages implicit in the use of permanent implants. The challenge is to produce a suitable material that is gradually replaced by new bone tissue without any loss of mechanical resistance. This chapter includes the state of the ar...
Article
Full-text available
Polylactic acid/Mg composites have been recently proposed for biodegradable osteosynthesis devices because, with regards to the neat polymer, they combine an enhanced biocompatibility and bioactivity with better mechanical properties, particularly creep strength. A question still arises about their bacterial behavior. For this purpose, composites o...
Article
In the field of bioabsorbable composites for biomedical applications, extrusion has been employed as a method to prepare homogeneous blends of polymeric matrices with bioactive ceramic fillers. In this work, the suitability of processing poly-L-lactic acid/Magnesium (PLLA/Mg) composites by hot extrusion has been assessed by a systematic characteriz...
Article
Full-text available
Laser shock processing (LSP) is increasingly applied as an effective technology for the improvement of metallic materials’ mechanical and surface properties in different types of components, mostly as a means of enhancement of their fatigue life behavior. As reported in previous contributions by the authors, a main effect resulting from the applica...
Article
Full-text available
We developed biodegradable polymeric coatings loaded with increasing amounts of dexamethasone on composites based on polylactic acid and Mg particles for bone repair. Incorporation of Mg particles into the polymeric matrix improves the compressive behaviour of the polymer. Mg-containing composites release Mg²⁺ ions into the culture medium and impro...
Article
Full-text available
Abstract This work deals with the mechanical characterization by depth-sensing indentation (DSI) of PLLA and PLDA composites reinforced with micro-particles of Mg (up to 15 wt.%), which is a challenging task since the indented volume must provide information of the bulk composite, i.e. contain enough reinforcement particles. The composites were fab...
Article
Full-text available
Free access to this article until June 7, 2016 in the following link: http://authors.elsevier.com/a/1SupR3IWkbm~a4 This work deals with the surface modification of 316LVM stainless steel by Si+ ion implantation and the in vitro study of its effect on the short-term corrosion behaviour and ion release. In order to achieve a high Si content close to...
Article
Full-text available
The ductile-to-brittle transition (DBT) behavior of two similar Fe-Cr-Al oxide dispersion strengthened (ODS) stainless steels was analyzed following the Cottrell–Petch model. Both alloys were manufactured by mechanical alloying (MA) but by different forming routes. One was manufactured as hot rolled tube, and the other in the form of hot extruded b...
Article
Flat fatigue specimens of biomedical Ti6Al4V ELI alloy were surface-processed by high pressure waterjet peening (WJP) without abrasive particles using moderate to severe conditions that yield roughness values in the range of those obtained by commercial grit blasting (BL) with alumina particles. Fatigue behavior of WJP and BL specimens was characte...
Article
Along this work, the feasibility of using repetitive-impact tests with a cube-corner tip and low loads for obtaining quantitative fracture toughness values will be shown. It will be displayed that the impacts are able to produce a cracking similar to the pattern developed for the classical fracture toughness tests in structural ceramics. Moreover,...
Article
The limitations of stainless steel as prosthesis material should be overcome in order to better satisfy the required specifications in bone replacements. One strategy to improve the corrosion and wear resistance and diminish the ion release is the surface modification of the implants by protective coatings. In this work, thin films of FeAlCr alloy...
Conference Paper
Full-text available
This work studies the feasibility of using repetitive-nano-impact tests with a cube-corner tip and low loads for obtaining quantitative fracture toughness values in thin and brittle coatings. However, the length of the crack has to be lower than 10% of the total coating thickness to avoid substrate contributions. For this reason, and in order to en...
Presentation
Full-text available
The design of coatings in the field of engineering applications aims at a progressive shift to the development of “hard but tough” coatings. The difficulty in assessing their mechanical behaviour by conventional methods is behind the growing relevance of “in situ” experiments using instrumented microindentation technique. Nevertheless, the question...
Article
Full-text available
We investigated a Ti6Al4V alloy modified by means of laser peening in the absence of sacrificial coatings. As a consequence of the temperature rise during laser focusing, melting and ablation generated an undulated surface that exhibits an important increase in the content of titanium oxides and OH- ions. Human mesenchymal stem cells and osteoblast...
Article
This work studies the feasibility of using repetitive-nano-impact tests with a cube-corner tip and low loads for obtaining quantitative fracture toughness values in thin and brittle coatings. For this purpose, it will be assumed that the impacts are able to produce a cracking, similar to the pattern developed for the classical fracture toughness te...
Article
Full-text available
Aluminum matrix composites (AMC) are attractive structural materials for automotive and aerospace applications. Lightweight, environmental resistance, high specific strength and stiffness, and good wear resistance are promising characteristics that encourage research and development activities in AMC in order to extend their applications. Powder me...
Article
In this work, we investigated a new approach to incorporate Mg particles within a PDLLA matrix using a solvent-free commercially available process. PDLLA/Mg composites were manufactured by injection moulding and the effects of Mg incorporated into PDLLA on MSC and macrophage responses were evaluated. Small amounts of Mg particles (≤1 wt.%) do not c...
Article
Full-text available
Statement of significance: The increasing demand for temporary orthopaedic implants is the driving force to seek new strategies to decrease costs and simultaneously improve patients comfort as well as simplify surgical procedures. Resorbable medical devices must be developed in order to have an appropriate degradation rate in agreement with the he...
Article
Full-text available
Roughening of Ti6Al4V by blasting with alumina or zirconia particles improves the mechanical fixation of implants by increasing the surface area available for bone/implant apposition. Additional thermal oxidation treatments of the blasted alloy have already shown to be a complementary low-cost solution to enhancing the in vitro biocompatibility and...
Poster
Full-text available
Instrumented indentation technique is one of few available to investigate the mechanical properties along any kind of length range, i.e. from small volume, for instance: coating or thin layers, to bulk material. The resulting load-depth curve of indentation provides abundant and varied information that be used to determine several mechanical proper...
Poster
Full-text available
Constrain of current bioresorbable polymers for osteosynthesis, as poly-Dlactide (PLDA), are mainly related to their low mechanical properties, which is behind the increasing demand of new bioresorbable materials. Mg and its alloys are among the most interesting options because their suitable mechanical strength and stiffness. However, their use a...
Article
This aim of this study is to determine the elastoplastic properties of Ni-free Al3FeSi2 intermetallic coatings grown on medical stainless steel under different experimental conditions. Elastoplastic properties are defined by the plasticity index (PI), which correlates the hardness and the Young׳s modulus. Special emphasis is devoted to correlate th...
Article
The first part of this two-part study reported the possibility of simultaneously generating a dense, self-healing α-alumina layer by thermal oxidation and a coarse-grained microstructure with a potential goodness for high-temperature creep resistance in a FeCrAl oxide dispersion-strengthened ferritic alloy that was cold deformed after hot rolling a...
Article
Austenitic stainless steel 316 LVM (Low Vacuum Melting) is typically used in biomedical applications. However, its biocompatibility has always been in controversy since the passive film developed on the surface can release metallic ions (Ni2+, Cr3+ and Cr6+), which may cause local systemic effects into the human body and therefore, the premature fa...
Article
Laser peening has recently emerged as a useful technique to overcome detrimental effects associated with other well-known surface modification processes such as shot peening or grit blasting used in the biomedical field. It is worthwhile to notice that besides the primary residual stress effect, thermally induced effects might also cause subtle sur...
Poster
Full-text available
En la reparación ósea uno de los principales problemas del uso de materiales poliméricos, comparando con los metálicos, es su baja respuesta mecánica. Sin embargo, cada vez se demandan más materiales bioabsorbibles que combinen una buena degradación con una relativa estabilidad mecánica. Recientemente se ha publicado que la incorporación de metales...
Article
Blasting of 316 LVM steel was performed by using alumina and zirconia particles that yield rough (up to Ra ~8 µm) and nearly smooth (up to Ra ~1 µm) surfaces, respectively. Besides roughening, the severe plastic deformation imposed during blasting yields subtle sub-surface microstructural changes such as grain size refinement, α´-martensite formati...
Article
Full-text available
Poly-L-lactic acid, PLLA, is a widely studied biomaterial, currently approved for use in a range of medical devices. Its mechanical properties can be tailored giving the material different crystallinity degrees. PLLA presents a complex non-linear behaviour that depends not only on structural parameters such as crystallinity degree but also on exter...
Article
Full-text available
This paper addresses the influence of Mg on melting behaviour and thermal stability of novel bioreabsorbables PLLA/Mg composites as a way to investigate their processability by conventional techniques, which likely will require a melt process at high temperature to mould the material by using a compression, extrusion or injection stage. For this pu...
Article
A novel bone substitute incorporating biodegradable coatings on poly(D,L-lactide-co-lactide) (PLDL) implant has been developed. The polymer coatings were investigated as carrier of eugenol(EG) and dexamethasone (DM) which are suitable drugs to give antibacterial and anti-inflammatory function to the implant. The dip coating method was employed to c...
Article
AISI 316 LVM stainless steel was coated by hot-dipping into a molten bath containing Al–32 wt.% Si. The high-temperature oxidation behavior of coated AISI 316 alloy was studied between 700 and 900 °C for 150 h and the results compared with the uncoated alloy. The oxidation resistance of coated AISI 316 LVM alloy was substantially improved at 900°C...
Article
The design of coatings in the field of engineering applications aims at a progressive shift to the development of “hard but tough” coatings. The difficulty in assessing their mechanical behaviour by conventional methods is behind the growing relevance of “in situ” experiments using instrumented microindentation techniques. Determination of fracture...
Article
Full-text available
In this paper, we present a technique that can give information on surface metallic inclusions embedded in a host material, i.e. by the magnetic sensing of local thermoelectric currents produced when a temperature gradient is established in the material. These thermoelectric currents generate flux magnetic densities that are detected by a highly se...
Data
IntroductionThermoelectric TechniquesExperimental Method Results and DiscussionsConclusion Acknowledgements
Article
This work aims to develop polymer/magnesium composites as new biodegradable and bioresorbable materials for osteosynthesis implants. The polymeric matrix will benefit from the higher strength and modulus of the Mg particles, whereas Mg will benefit from the surrounded protective polymeric matrix that will control its degradation rate. To provide a...
Article
Grit blasting is a low cost surface modification treatment widely used to enhance mechanical fixation of implants through increasing their roughness. As a result of the severe surface plastic deformation, beneath the surface it produces additional effects such as grain size refinement, work hardening and compressive residual stresses, which are gen...
Article
Full-text available
This study reports on the biocompatibility of 316 LVM steel blasted with small and rounded ZrO(2) particles or larger and angular shaped Al(2)O(3) particles. The effect of blasting on the in vitro corrosion behavior and the associated ion release is also considered. Surface of Al(2)O(3) blasted samples was rougher than that of ZrO(2) blasted sample...
Patent
Full-text available
La presente invención se refiere a un procedimiento de obtención de un biomaterial, con recubrimiento metálico, mediante un método metalúrgico de inmersión de un sustrato metálico de base de titanio en una aleación fundida de aluminio y silicio. A su vez la presente invención se refiere al uso de dicho biomaterial para aplicaciones biomédicas
Patent
Full-text available
La presente invención se refiere a un material de matriz polimérica y partículas de magnesio, biocompatible y reabsorbible con aplicaciones médicas en concreto para su aplicación como material de osteosíntesis y en ingeniería tisular ósea para la regeneración de tejido óseo
Conference Paper
Full-text available
The grit blasting is a low-cost technique successfully used to enhance mechanical fixation of the implants through increasing their roughness. As a result of the severe plastic surface deformation, it produces subsurface effects such as grain refinement, hardening and compressive residual stresses which are generally evaluated with destructive tech...
Article
The colonization of an implant surface by bacteria is an extremely important medical problem, which often leads to the failure of medical devices. Modern surface modification techniques, such as ion implantation, can confer to the surfaces very different properties from those of the bulk underlying material. In this work, austenitic stainless steel...
Patent
Full-text available
The invention relates to a process for producing a metal-coated biomaterial, by means of a metallurgic method of immersing a titanium metal substrate in a molten alloy of aluminum and silicon. The invention further relates to the use of said biomaterial in biomedical applications.
Article
This study addresses the roughening of AISI 316 LVM and Ti6Al4V by waterjet peening (WJP) without abrasive particles, looking for rough surfaces free of embedded particles that could act as severe notches. Strong parameters have been selected to characterize and check viability of abrasiveless WJP; a water pressure of 360MPa and two slow traverse v...
Article
Full-text available
Commercial 316 LVM austenitic stainless steel samples have been coated by immersion in a bath of molten Al-12.6%Si alloy for 120 s. The coating consists of the Al(12)(Fe,Cr)(3)Si(2) intermetallic. In vitro corrosion behaviour has been evaluated in the Ringer's solution by means of potentiodynamic curves and electrochemical impedance spectroscopy. T...
Article
Patterned surfaces direct cell spatial dynamics, yielding cells oriented along the surface geometry, in a process known as contact guidance. The Rho family of GTPases controls the assembly of focal adhesions and cytoskeleton dynamics, but its role in modulating bone-cell alignment on patterned surfaces remains unknown. This article describes the in...
Article
Advanced nanomechanical testing has been used to evaluate mechanical properties of Ni-free Al12(Fe,Cr)3Si2 intermetallic coatings grown on the 316 LVM steel by hot dipping in a Al-12.6 at.% Si liquid alloy for various immersion times. Despite the ultrafine-grained structure of the coating (∼200 nm), the indentation size effect is more pronounced fo...
Data
The colonization of an implant surface by bacteria is an extremely important medical problem, which often leads to the failure of medical devices. Modern surface modification techniques, such as ion implantation, can confer to the surfaces very different properties from those of the bulk underlying material. In this work, austenitic stainless steel...
Data
Full-text available
Introduction The austenitic stainless steel 316 LVM combines both good mechanic properties with a reasonable in vitro biocompatibility and in vivo tolerance. Thus, it is used for orthopedic applications. One method to improve the implant osseointegration is to increase the roughness by grit blasting. This study focus on the in vitro corrosion behav...