Jose Criado

• University of Salamanca

In this study, binary logistic regression and linear regression analyses were used to examine the relationship between interoceptive body awareness and suicidal orientation among Colombian university students. Additionally, the bootstrap technique was employed to resample and estimate the distribution of the data. The results support the idea that...

Suicide is a public health problem influenced by a variety of biological, psychological, social, and environmental factors. Recognizing the warning signs at each stage is crucial for prevention and helping those at risk. In this context, body awareness, especially interoceptive body awareness, emerges as a potentially relevant and underexplored fac...

Introduction: The transition to college life can impact the mental health of students. There are mental health care strategies that promote connection with the body's internal signals, which can help to improve mental well-being, manage emotions, and reduce the risk of suicide in university students. Aim: This study aimed to examine the associat...

The barriers faced by people with intellectual disabilities are many. One of the areas in which many problems have been identified is the sexual domain. This descriptive study aims to analyze the attitudes of the family environment, professional carers, and the general population toward their sexuality. A cross-sectional descriptive study was carri...

Introduction: The university student population is influenced by multiple factors that affect body awareness. Identifying the body awareness status of students is crucial in creating self-care and emotion management programs to prevent diseases and promote health. The Multidimensional Assessment of Interoceptive Awareness (MAIA) questionnaire eval...

Traumatic brain injury represents one of the main health problems in developed countries. Growth hormone (GH) and rehabilitation have been claimed to significantly contribute to the recovery of lost motor function after acquired brain injury, but the mechanisms by which this occurs are not well understood. In this work, we have investigated cell pr...

Traumatic brain injury represents one of the main health problems in developed countries. Growth Hormone (GH) and rehabilitation have been claimed to significantly contribute to the recovery of lost motor function after acquired brain injury, but the mechanisms by which this occurs are not well understood. In this work, we have investigated cell pr...

Background: Heart failure (HF) is a progressive and debilitating condition that represents an ever-growing problem for health systems worldwide. HF patients feel that they are a burden on their families, they feel socially isolated and have a low perception of their health. Accordingly, the objectives of this study were to: (1) to explore the profi...

Previously we demonstrated, in rats, that treatment with growth hormone (GH) and rehabilitation, carried out immediately after a motor cortical ablation, significantly improved the motor affectation produced by the lesion and induced the re-expression of nestin in the contralateral motor cortex. Here we analyze cortical proliferation after ablation...

Previously we demonstrated, in rats, that the treatment with growth hormone (GH) and rehabilitation, carried out immediately after a motor cortical ablation, significantly improved the motor affectation produced by the lesion and induced the re-expression of nestin in the contralateral motor cortex. Here we analyze cortical proliferation after abla...

Using an immunohistochemical technique, we have studied the distribution of kynuneric acid (KYNA) and 3-hydroxyanthranilic acid (3-HAA) in a rat brain injury model (trauma). The study was carried out inducing a cerebral ablation of the frontal motor cortex. Two mouse monoclonal specific antibodies previously developed by our group directed against...

We previously demonstrated that the administration of GH immediately after severe motor cortex injury, in rats, followed by rehabilitation, improved the functionality of the affected limb and reexpressed nestin in the contralateral motor cortex. Here, we analyze whether these GH effects depend on a time window after the injury and on the reexpressi...

Background Due to the absence of agreement about an effective unified treatment for temporomandibular disorders, non-invasive therapies such as EMG-biofeedback generate a greater interest. Furthermore, most studies to the present show methodological deficiencies that must be solved in the future, which makes important to emphasize this line of stud...

En este libro se recogen terapias psicológicas y neurológicas novedosas, de última generación, de uso en personas mayores con demencia o con deterioros asociados a la edad, pero terapias basadas en la evidencia, así como publicadas y refrendadas en estudios científicos. De una forma muy sencilla, se ofrecen pautas prácticas para el uso de estas ter...

Intracellular recordings in slice preparations of the basolateral amygdala were used to test which excitatory amino acid receptors mediate the excitatory postsynaptic potentials due to stimulation of the external capsule. These recordings were also used to examine the action of muscarinic agonists on the evoked excitatory potentials. Intracellular...

The aging of the population has led to the increase of chronic diseases, especially dementia and cardiovascular diseases, and it has become necessary for their relatives to dedicate more time in caregiving.The objective in the first phase of this study is to evaluate the effectiveness of a Primary Health Care procedure to increase the physical acti...

Objetive: To investigate whether transplants of encapsulated astrocytes in alginate spheres were able to recover the deficit in motor skills produced by frontal cortex lesion, in adult rats. Material and method: Male Wistar rats were used. Behavioral test, tissue culture, astrocyte transplants and immunocytochemical and histological techniques were...

Transplants of embryonic nervous tissue ameliorate motor deficits induced by motor cortex lesions in adult animals. Restoration of lost brain functions has been recently shown in grafts of homotopic cortical origin, to be associated with a functional integration of the transplant after development of reciprocal host–graft connections. Nevertheless...

Objective: Lesions of the frontal cortex produce motor deficits which are evident at three months post-injury. The aim of this study was to investigate whether short-term rehabilitation in a critical period post-injury improves the deficit in motor ability produced by motor cortex lesions in adult rats. Additionally, we studied the expression of t...

Objective: We have previously shown the functional recovery of skilled forelimb use in rats after grafting of the frontal cortex lesion with cortical or amygdalar fetal tissue when rats were obliged to use the impaired limb. Here, we aimed to explore the effects of astrocyte grafts on the motor impairments caused by frontal cortex lesion in adult...

Lesions in specific areas of the rat motor cortex generate deficits related to fine movement performance affecting the forelimb. We have previously shown that transplants of embryonic frontal cortex ameliorate these motor deficits. Amelioration has been associated with a functional integration of the transplant due to the connections established be...

Objetive: To investigate the mechanisms by which neural transplants contribute to functional recovery of the motor disorders produced by frontal cortex damage in adult rats. Material and methods: Male Wistar rats were used, with the application of behavioral tests, electrophysiologi-cal methods and immunohistochemical and histological techniques. T...

The precision of human movements to generate skills as accurate as the exercises performed by athletes are the consequence of a long and complex learning process. These processes involve a great amount of the nervous system's structures. Electrophysiological techniques have been largely used to highlight brain functions related to the control of th...

The medial septum/diagonal band region, which participates in learning and memory processes via its cholinergic and GABAergic projection to the hippocampus, is one of the structures affected by beta amyloid (betaA) deposition in Alzheimer's disease (AD). The acute effects of betaA (25-35 and 1-40) on action potential generation and glutamatergic sy...

The effects of beta-amyloid peptide25-35 on resting membrane potential, spontaneous and evoked action potential and synaptic activity have been studied in basolateral amygdaloid complex on slices obtained from adult rats. Intracellular recordings reveal that perfusion with beta-amyloid peptide25-35 at concentrations of 400 nM and less did not gener...

Cisplatin-bile acid derivatives belonging to the Bamet-family maintain both liver organotropism and cytostatic activity. "In vivo" toxicity and usefulness as chemotherapeutic agent versus liver tumors of a novel drug, Bamet-UD2 [cis-diamminechlorocholylglycinate platinum (II)], with enhanced "in vitro" cytostatic activity was investigated. Using or...

The long-term effect of transplanting embryonic frontal cortex into a unilateral frontal cortex lesion has been studied in adult rats. Before surgery, activity in an open field, muscular strength of both forelimbs, and performance in a paw-reaching-for-food task were scored in 26 rats. In 21 animals a unilateral cortex lesion was then made in the f...

Intracellular recordings in slice preparations of the basolateral amygdala were used to test which excitatory amino acid receptors mediate the excitatory postsynaptic potentials due to stimulation of the external capsule. These recordings were also used to examine the action of muscarinic agonists on the evoked excitatory potentials. Intracellular...

1. The discharge patterns of 117 lateral cerebellar neurones were studied in cats during visually guided stepping on a horizontal circular ladder. Ninety per cent of both nuclear cells (53/59) and Purkinje cells (53/58) showed step-related rhythmic modulations of their discharge frequency (one or more periods of 'raised activity' per step cycle of...

In the present study, a cationic membrane conductance activated by the acetylcholine agonist carbachol was characterized in vitro in neurons of the basolateral amygdala. Extracellular perfusion of the K+ channel blockers Ba2+ and Cs+ or loading of cells with cesium acetate did not affect the carbachol-induced depolarization. Similarly, superfusion...

Two human neural cell lines were examined after intracerebral transplantation in nonimmunosuppressed adult rats. BE(2)-M17 neuroblastoma cells or NT2 teratocarcinoma cells genetically modified with the tyrosine hydroxylase (TH) gene were transplanted into four brain regions: neocortex, cerebellum, striatum and amygdala. The survival and proliferati...

1. The discharge patterns of 166 lateral cerebellar neurones were studied in cats at rest and during visually guided stepping on a horizontal circular ladder. A hundred and twelve cells were tested against one or both of two visual stimuli: a brief full-field flash of light delivered during eating or rest, and a rung which moved up as the cat appro...

The electrophysiological properties, the response to cholinergic agonists and the morphological characteristics of neurons of the basolateral complex were investigated in rat amygdala slices. We have defined three types of cells according to the morphological characteristics and the response to depolarizing pulses. Sixty-six of the recorded cells (...

The prefrontal cortex is involved in many processes, some of which are related to motor activity such eye movements and speech. Experimental data exist that suggest that prefrontal cortical activity occurs in relation to attention, short-term memory, affective discrimination, and complex forms of motor behaviour, i.e. anticipatory preparation, moto...

1. The impulse activity of single neurones in the forelimb part of the motor cortex was recorded extracellularly in unrestrained cats during self-paced locomotion on a horizontal circular ladder. 2. Fifty-one cells (forty-nine of which discharged rhythmically in time with the step cycle) were recorded during encounters with a number of rungs that c...

Single unit activity was recorded in the basolateral amygdaloid nucleus in two series of rats. In the first series, activity was recorded under control conditions and 1 minute and 24 hours after the application of a foot-shock. In the second series, activity was recorded in control conditions, during a low intensity flash stimulation and 1 minute l...

Lesion studies have shown that the functional integrity of prefrontal and posterior parietal cortex is necessary for complex behavioural performance. Recordings were made from 137 prefrontal cells in awake cats. Parietal cortex stimulation affected fifty-four cells (39.5%); thirty-four (63%) increased and twenty (37%) decreased their discharge freq...

Single unit activity was recorded in the basolateral nucleus of amygdala in rats in a passive avoidance test. Simultaneously, visual control of exploratory behaviour was carried out. Prior to establishing the conditioning, the mean frequency of the unit discharge was 14 Hz (SD = 9) and 1 minute after conditioning this unit activity decreased to val...

Acute experiments were performed on anaesthetized rats using standard techniques of electrical stimulation and single-unit recording in order to study the responses of the bed nucleus of the stria terminalis (BNST) neurons to homo- and contralateral stria terminalis (ST) inputs. Satisfactory records were obtained from 174 BNST neurons. The majority...

The commissural component of the stria terminalis (S. T.) was studied in Equi-Thesin (92.7 mg/kg) anesthetized rats after their exposure in the caudothalamic surface of both hemispheres. Two types of connection between right and left S. T. across the anterior commissure are described: A "direct" connection set up by fibres that run through the S. T...