Jose A Barasona

Jose A Barasona
Complutense University of Madrid | UCM · SUAT-VISAVET, Department of Animal Health (UCM) Spain

DVM, MSc, PhD

About

118
Publications
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Publications

Publications (118)
Article
Full-text available
African Swine Fever (ASF) is one of the most complex and significant diseases from a sanitary-economic perspective currently affecting the world’s swine-farming industry. ASF has been endemic in Sardinia (Italy) since 1978, and several control and eradication programmes have met with limited success. In this traditional ASF endemic area, there are...
Article
Full-text available
The presence of Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex (MTC) is a main concern in wildlife populations such as the Eurasian wild boar (Sus scrofa). Tests detecting antibodies against the MTC are valuable for tuberculosis (TB) monitoring and control and particularly useful in suids. The development of accurat...
Article
Assessing Eurasian wild boar (Sus scrofa) mortality is a key for understanding population dynamics and adjusting hunting harvest and population management. We used radio-tagging and video-trapping to quantify piglet summer mortality in a managed (i.e. fenced and year-round fed) wild boar population from southern Spain. We used two independent tools...
Article
Full-text available
Current scientific debate addresses whether species richness in animal communities may negatively moderate pathogen transmission and disease outcome (dilution effect), or to the contrary, if disease emergence benefits from more diverse community assemblages (amplification effect). The result may not depend exclusively on patterns of host species bi...
Article
Full-text available
African swine fever (ASF), the most significant threat to the pig industry worldwide, has spread to more than 55 countries on three continents, and it affects more than 77% of the world swine population. In the European Union, wild boar (Sus scrofa) is the most severely affected host. The main reasons for the unprecedented and constant spread of AS...
Article
Full-text available
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the current pandemic disease denominated as Coronavirus Disease 2019 (COVID-19). Several studies suggest that the original source of this virus was a spillover from an animal reservoir and its subsequent adaptation to humans. Of all the different animals affected...
Article
Full-text available
Background: Fences are one of the most widespread manmade features in nature, constituting an artificial limitation to the movement of wildlife. To date, their effects on wildlife behaviour have been understudied but this knowledge is required to design effective management procedures. Using 21 GPS-monitored wild boar, we evaluated the permeability...
Article
Full-text available
African swine fever (ASF) is a highly lethal infectious disease that affects domestic pigs and wild boar. Outbreaks of ASF have grown considerably in the last decade causing important economic consequences for the swine industry. Its control is hampered by the lack of an effective treatment or vaccine. In Europe, the wild boar is a key wild reservo...
Article
Full-text available
African swine fever (ASF) is currently the most dangerous disease for the global pig industry, causing huge economic losses, due to the lack of effective vaccine or treatment. Only the early detection of ASF virus (ASFV) and proper biosecurity measures are effective to reduce the viral expansion. One of the most widely recognized risks as regards t...
Book
Full-text available
This book, aimed at professionals in the sector such as veterinarians, livestock farmers or wildlife managers, is the first volume of a manual that lists and details the different sources of risk of tuberculosis for cattle. In each section, the risk is described, its epidemiological role is detailed and control measures are proposed, providing a co...
Article
Bluetongue is a vector-borne disease affecting domestic and wild ruminants, with a major socioeconomic impact. Endemic circulation of the bluetongue virus serotype 4 (BTV-4) and BTV-1 have occurred in Spain since 2004 and 2007, respectively. However, epidemiological studies have seldom been approached from a long-term perspective in wild ruminants....
Article
Full-text available
Little is known about the role of ticks in maintaining highly prevalent zoonotic viruses in wildlife, such as hepatitis E virus (HEV), which do not require ticks for transmission between animals and humans. In this cross-sectional study, adult female ticks were collected from Eurasian wild boar (Sus scrofa) in autumn 2015 in Spain. HEV RNA in both...
Article
The ubiquitous wild boar is causing diverse and growing conflicts of socio-ecological and economic relevance worldwide. For that reason, knowledge of its spatial ecology is crucial to designing effective management programmes. But this knowledge is scarce in Mediterranean areas with mixed land uses. We describe the spatial ecology and habitat selec...
Article
Full-text available
The hepatitis E virus (HEV) is an emerging zoonotic pathogen whose main reservoir is suids. Most of the ecological and epidemiological aspects of its sylvatic cycle remain unknown. Thus, in this work, we study the drivers of HEV exposure in the wild boar population of Doñana National Park (DNP, southwest Spain) operating in the medium and long-term...
Article
Full-text available
African swine fever virus (ASFv) is one of the most challenging pathogens to affect both domestic and wild pigs. The disease has now spread to Europe and Asia, causing great damage to the pig industry. Although no commercial vaccine with which to control the disease is, as yet, available, some potential vaccine candidates have shown good results in...
Article
Full-text available
Wildlife management and conservation requires monitoring of species distribution and population indicators, especially when the unbalanced demographic changes of some species can affect the whole ecosystem functioning. The populations of wild boar (Sus scrofa) have, over the past few decades, undergone an expansion around the world, reaching situat...
Chapter
The study of wildlife/livestock interfaces has long suffered from the sealing among the different agricultural - including veterinary - and environmental sectors and the lack of multidisciplinary approaches. Following the SARS and H5N1 crisis, bridges have been developed between sectors and different disciplines, especially between the fields of ep...
Article
Animal tuberculosis (TB), which is caused by the Mycobacterium tuberculosis complex (MTC), is a zoonotic disease of global concern, and has a wide variety of wild and domestic reservoirs that can establish complex epidemiological systems. Of all the strategies employed to control TB, reducing the risks of interaction at the wildlife-livestock inter...
Article
The knowledge regarding the spatial ecology of red deer (Cervus elaphus) in different environments is crucial if effective management actions are to be designed. However, this knowledge continues to be scarce in the complex contexts of mixed land use and management circumstances. This study describes the spatial ecology of red deer monitored using...
Article
Full-text available
African swine fever (ASF) is currently the major concern of the global swine industry, as a consequence of which a reconsideration of the containment and prevention measures taken to date is urgently required. A great interest in developing an effective and safe vaccine against ASF virus (ASFV) infection has, therefore, recently appeared. The objec...
Article
Full-text available
Understanding the dynamics of a wildlife population in relation to hunting strategies is essential to achieve sustainable management. We used monitoring data over 25 years from two red deer (Cervus elaphus) populations with different management (with and without supplemental feeding) in South Central Spain to: (i) characterise the density dependenc...
Article
Full-text available
More effective methods to detect bovine tuberculosis, caused by Mycobacterium bovis, in wildlife, is of paramount importance for preventing disease spread to other wild animals, livestock, and human beings. In this study, we analyzed the volatile organic compounds emitted by fecal samples collected from free-ranging wild boar captured in Doñana Nat...
Article
Full-text available
Since the reappearance of African swine fever virus (ASFV), the disease has spread in an unprecedented animal pandemic in Eurasia. ASF currently constitutes the greatest global problem for the swine industry. The wild boar (Sus scrofa) in which the pathogen has established wild self-sustaining cycles, is a key reservoir for ASFV, signifying that th...
Article
Full-text available
Early detection of infectious diseases is the most cost-effective strategy in disease surveillance for reducing the risk of outbreaks. Latest deep learning and computer vision improvements are powerful tools that potentially open up a new field of research in epidemiology and disease control. These techniques were used here to develop an algorithm...
Article
The effective management of shared pathogens between wild ungulates and livestock requires the understanding of the processes of interaction between them. In this work we studied the interspecific frequency of interaction (ifreq) and its spatio-temporal pattern between wild and domestic ungulates that coexist in free-ranging farms. For this purpose...
Article
Full-text available
Abstract The physiological significance of biometric body condition indices (bBCI) is poorly understood. We hypothesized that bBCI are composite metrics of nutritional physiology, physical fitness and health. To test this hypothesis, we first compared the performance of eight bBCI, using 434 Southern European carnivores from six species as a model...
Article
Full-text available
African swine fever (ASF) is a notifiable disease that in recent years has spread remarkably in Europe and Asia. Eurasian wild boar (Sus scrofa) plays a key role in the maintenance and spread of the pathogen. Here we examined gross pathology of infection in wild boar with a highly virulent, hemadsorbing genotype II ASF virus (ASFV) strain. To this...
Article
Full-text available
Animal tuberculosis (TB) is endemic in wild boar (Sus scrofa), red deer (Cervus elaphus), fallow deer (Dama dama) and cattle in south and central Spain. In order to clarify the processes that operate in the medium and long-term, we studied TB at the wildlife–livestock interface in Doñana National Park for 14 years (2006–2018) in relation to host de...
Article
Full-text available
The presence of Mycobacterium tuberculosis complex (MTBC) in wild swine, such as in wild boar (Sus scrofa) in Eurasia, is cause for serious concern. Development of accurate, efficient, and noninvasive methods to detect MTBC in wild swine would be highly beneficial to surveillance and disease management efforts in affected populations. Here, we desc...
Article
Full-text available
Traditional VHF radio-tracking is gradually being replaced by GPS tracking devices in spatial ecology studies, although both technologies continue to be used. Differences between tracking regimes (time and fix frequency) may lead to home range estimates that are not directly comparable. Our primary aim was to test the reliability of comparisons in...
Article
Full-text available
: African swine fever (ASF) is a viral disease of domestic and wild suids for which there is currently no vaccine or treatment available. The recent spread of ASF virus (ASFV) through Europe and Asia is causing enormous economic and animal losses. Unfortunately, the measures taken so far are insufficient and an effective vaccine against ASFV needs...
Article
Full-text available
The correct management of diseases that are transmitted between wildlife and livestock requires a reliable estimate of the pathogen transmission rate. The calculation of this parameter is a challenge for epidemiologists, since transmission can occur through multiple pathways. The social network analysis is a widely used tool in epidemiology due to...
Article
Full-text available
African swine fever virus (ASFV) is spreading throughout Eurasia and there is no vaccine nor treatment available, so the control is based on the implementation of strict sanitary measures. These measures include depopulation of infected and in-contact animals and export restrictions, which can lead to important economic losses, making currently Afr...
Article
Day range (DR), the distance travelled by an individual during the day, is an important metric in movement ecology that recently gained interest by its relevance for estimating population density through the random encounter model (REM). Traditionally, DR has been estimated using GPS technology and considering raw straight-line distances between co...
Article
Wild boar (Sus scrofa) is considered the main wildlife reservoir of zoonotic hepatitis E virus (HEV) genotypes. The aim of this study was to evaluate the circulation of HEV in free‐ranging wild boar in the Doñana National Park (DNP), Spain. Blood samples were collected from 99 wild boar in the DNP during 2015. Sera were analyzed in parallel using i...
Article
Full-text available
Controlling infections shared by wildlife and livestock requires the understanding and quantification of interspecific interactions between the species involved. This is particularly important in extensive multi-host systems, in which controlled domestic animals interact with uncontrolled, abundant and expanding wild species, such as wild ungulates...
Data
Activity patterns (km/h) for cattle and wild boar in Doñana National Park, calculated from the locations obtained during the study period. (DOCX)
Data
GPS data collection and number of interspecific interactions per month for each collared individual (wild boar or cattle), throughout the study period in Doñana National Park. (DOCX)
Data
Relevant data concerning the number of recorded interspecific interaction and their date, time and coordinates. (DOCX)
Article
Full-text available
The red deer (Cervus elaphus) is a widespread wild ungulate in Europe that has suffered strong anthropogenic impacts over their distribution during the last centuries, but also at the present time, due its economic importance as a game species. Here we focus on the evolutionary history of the red deer in Iberia, one of the three main southern refug...
Data
Mitochondrial D-loop phylogeography. The red deer mitochondrial D-loop haplotypes (329 bp) included in the phylogeographic analysis at a European level. (XLSX)
Data
Mitochondrial D-loop phylogeography. Mitochondrial D-loop similarity between the red deer haplotypes found in the present study and those reported by Niedziałkowska et al. [84]. For this comparison a 248 bp fragment size was considered. (DOCX)
Data
Species distribution modelling. The bioclimatic variables used to study the climatic requirements of Cervus elaphus distribution throughout western Europe and North Africa. A ‘quarter’ refers to a fraction of the year (i.e. three months). The same variables are available for present (1950–2000), Mid-Holocene (6 ky BP), Last Glacial Maximum (22 ky B...
Data
Population demography and divergence inferred by the program DIYABC using microsatellite data. Posterior parameter estimates (median and 95% confidence intervals) for the best-supported scenario calculated using 1% of simulated datasets closest to the observed values. Simulations and approximate Bayesian computation analyses were performed includin...
Data
Species distribution modelling. Climatic suitability for the occurrence of Cervus elaphus in western Europe and North Africa during the Mid-Holocene (6 ky BP), Last Glacial Maximum (LGM, 22 ky BP) and interglacial period (120 ky BP) represented for the generalized boosting model (GBM), classification tree analysis (CTA) and the ensemble of their fo...
Data
Archaeological data and species distribution model for red deer during the LGM. Map showing the geographic distribution of the red deer fossil records dated within the period of Last Glacial Maximum (Fig 9) and the climatic suitability for occurrence of red deer at 22 kyBP (Fig 8), predicted according to the climatic niche for the species determine...
Data
Mitochondrial D-loop phylogeography. Mitochondrial D-Loop similarity between the red deer haplotypes found in the present study and those reported by Meiri et al. [15]. For this comparison a 316 bp fragment size was considered, which after excluding nucleotide sites with gaps and missing data resulted in a total of 180 nucleotide sites analysed. (D...
Data
Mitochondrial D-loop phylogeography. Mitochondrial D-Loop similarity between the red deer haplotypes found in the present study and those reported by Rey-Iglesia et al. [37]. For this comparison a 670 bp fragment size was considered, which after excluding nucleotide sites with gaps and missing data resulted in a total of 449 nucleotide sites analys...
Data
Analysis of population structure. Plots showing the results for both the Bayesian clustering analyses conducted in STRUCTURE software (see Figs 3A and 4A and S4 Fig) and the highest ΔK value obtained following Evanno et al. [59] procedures. (DOCX)
Data
Isolation-by-distance in the Iberian red deer populations. Plots showing the relationship between genetic distance [pairwise FST/(1-FST)] and geographic distance (log km) between the Iberian red deer populations quantified for both microsatellites and mitochondrial datasets (isolation-by-distance). (DOCX)
Data
Population structure of the European red deer populations. Bayesian clustering analyses performed in STRUCTURE [56] on microsatellite data from the central and north European red deer populations, considering the best ΔK values obtained following Evanno et al. [59] procedures (see also S1 Fig). Proportional membership to each cluster is indicated f...
Data
Mitochondrial D-loop phylogeography of red deer. Median joining network showing the evolutionary relationship of D-loop haplotypes found in this study (670 bp fragment size) for the red deer in Europe. Numbers within circles correspond to haplotype name described in the main manuscript for the 329 bp haplotypes (see details in S1 Table). A bar on e...
Data
Mitochondrial D-loop phylogeography. Mitochondrial D-Loop similarity between the red deer haplotypes found in the present study and those reported by Stanton et al. [26]. For this comparison a 328 bp fragment size was considered, which after excluding nucleotide sites with gaps and missing data resulted in a total of 264 nucleotide sites analysed....
Data
Pairwise FST values for both microsatellite (above diagonal) and mitochondrial (below diagonal) datasets for the red deer populations studied. Population codes are described as in Fig 1 of the main manuscript. (DOCX)
Data
European red deer differentiation inferred using nuclear and mitochondrial markers. Neighbor-joining trees representing the genetic differentiation among populations measured as pairwise FST for both microsatellite (left) and mtDNA (right) datasets. Population codes are described in Fig 1 of the main manuscript. (DOCX)
Data
Mitochondrial D-loop evolutionary rate. Ancient DNA mitochondrial D-loop sequences used for the inference of within-species evolutionary rate. (DOCX)
Data
Mitochondrial D-loop evolutionary rate. Bayesian MCMC analysis performed to estimate the evolutionary rate of the D-loop mitochondrial fragment studied, using calibrated fossil ages of red deer from Europe (see S6 Table). Results of independent runs were combined using TRACER, version 1.5 [87], the final result was given based on average Log10 of t...
Data
Species distribution modelling. Results of the generalized linear model (GLM) model developed for the current distribution of Cervus elaphus in western Europe and North Africa. Predictors are listed following the order of inclusion in a stepwise procedure (the first one on top). The coefficient and its standard error (SE) and z-value test statistic...
Data
Species distribution modelling. Results of the generalized additive model (GAM), generalized boosting model (GBM), classification tree analysis (CTA), artificial neural network (ANN), flexible discriminant analysis (FDA) and, in addition, an ensemble of their forecasts, developed on the current distribution of Cervus elaphus in western Europe and N...